Uploaded December 2025 | Updated September 2026, 2 weeks ago

---

Chronic Myelogenous Leukemia (CML) is a myeloproliferative disorder caused by the BCR-ABL fusion gene formed due to the Philadelphia chromosome translocation t(9;22). In this video, we clearly explain the molecular pathogenesis of CML, focusing on BCR-ABL tyrosine kinase activity, uncontrolled cell proliferation, and reduced apoptosis. This video is highly useful for USMLE, NEET, AIIMS, and medical entrance exam preparation. Learn the genetics behind CML, clinical significance of the Philadelphia chromosome, and how targeted therapy like imatinib works. Ideal for medical students, pathology, molecular biology, and oncology learners seeking concept clarity and quick revision.
For Notes, flashcards, daily quizzes, and practice questions follow
Instagram page: instagram.com/animatedbiologywitharpan
Facebook page: facebook.com/Animated-biology-with-Arpan-109894017509038/?ref=pages_you_manage

Follow me on other social media -
Facebook : https://www.facebook.com/arpan.parich...
Instagram : instagram.com/arpanparichha
Linked in : https://in.linkedin.com/in/arpan-pari...
Twitter : https://twitter.com/arpan_parichha?la...

Link to my other channel - Lets crack bio exams youtube.com/channel/UC4IpyopsGWSjaPACNTZLuqg

The Nerd Medic YouTube channel:
Youtube: youtube.com/c/TheNerdMedic00
Instagram: https://instagram.com/ayan_parichha00...
Facebook: facebook.com/poetsoflens

For Physics part of bio exams - Physics for IIT JAM biotechnology
youtube.com/channel/UCJvSHjOoL2FDN85hQbu7vfw

#animated_biology #animated_biology_with_arpan #biology #bio_facts #CSIR_NET #IIT_JAM #IIT_JAM_BT #biotechnology #bioscience #biological_sciences #microbiology #genetics #zoology #molecular_biology #cell_biology #botany #immunology #ecology