WEHImovies | Art of Science behind the scenes | M-Galaxy by Roberto Bonelli @WEHImovies | Uploaded July 2018 | Updated October 2024, 2 hours ago.
Like charting new territory in a vast galaxy, Roberto is exploring the body’s metabolism to uncover the cause of a rare and incurable eye disease that can lead to blindness called macular telangiectasia (MacTel).
Previous Institute research revealed that abnormalities in the metabolism of patients with MacTel could help to explain how the disease occurs.
Roberto – a bioinformatician – is making sense of masses of data from studies on the metabolism of MacTel patients. M-Galaxy is a visualisation of the clues found in these data.
In this image, each dot represents a different molecule found in the metabolism, called a metabolite. The bigger the dot the more likely that metabolite plays a role in MacTel, warranting further investigation. The dots in the outer ring are metabolites of no particular consequence to the disease and therefore limited interest to the study.
By highlighting key differences between metabolites in the blood of MacTel patients versus those without the disease, Roberto is advancing the quest to hopefully one day cure or prevent the devastating disease.
https://www.wehi.edu.au/artofscience
Like charting new territory in a vast galaxy, Roberto is exploring the body’s metabolism to uncover the cause of a rare and incurable eye disease that can lead to blindness called macular telangiectasia (MacTel).
Previous Institute research revealed that abnormalities in the metabolism of patients with MacTel could help to explain how the disease occurs.
Roberto – a bioinformatician – is making sense of masses of data from studies on the metabolism of MacTel patients. M-Galaxy is a visualisation of the clues found in these data.
In this image, each dot represents a different molecule found in the metabolism, called a metabolite. The bigger the dot the more likely that metabolite plays a role in MacTel, warranting further investigation. The dots in the outer ring are metabolites of no particular consequence to the disease and therefore limited interest to the study.
By highlighting key differences between metabolites in the blood of MacTel patients versus those without the disease, Roberto is advancing the quest to hopefully one day cure or prevent the devastating disease.
https://www.wehi.edu.au/artofscience
