Uploaded August 2026 | Updated September 2026, 3 weeks ago
Guest: Mackram Eleid, M.D.
Host: Malcolm Bell, M.D.
Dr. Malcolm Bell interviews Dr. Dr. Mackram Eleid on the diagnosis and management of aortic stenosis in younger patients, as well as discussing patient-centered decision-making considerations for lifetime management of aortic stenosis. After review, listeners will understand current indications as well as advantages and disadvantages of transcatheter versus aortic valve replacement for younger patients with aortic stenosis.
Topics Discussed:
• What factors are taken into account when considering lifetime management of aortic stenosis?
• Can valve in valve be performed inside of a transcatheter aortic valve replacement (TAVR) prosthesis?
• Who are the patients that are better served with surgical aortic valve replacement (SAVR)?
0:00 Managing Aortic Stenosis in Younger Patients
1:10 Defining the Younger Aortic Stenosis Patient
3:25 Evidence Comparing TAVR and Surgical Replacement
5:20 Bicuspid Valves and Emerging Clinical Trials
7:07 Planning for Future Valve-in-Valve Procedures
8:26 How Valve-in-Valve Replacement Works
10:54 When Surgery May Be the Better Choice
13:18 Choosing Between Tissue and Mechanical Valves
15:32 Trials and Guidelines for Younger Patients
16:55 Preserving Future Access to Coronary Arteries
18:20 Shared Decision-Making and Treatment Priorities
20:40 Continuing Cardiovascular Education at Mayo Clinic
Guest: Mackram Eleid, M.D.
Host: Malcolm Bell, M.D.
Dr. Malcolm Bell interviews Dr. Dr. Mackram Eleid on the diagnosis and management of aortic stenosis in younger patients, as well as discussing patient-centered decision-making considerations for lifetime management of aortic stenosis. After review, listeners will understand current indications as well as advantages and disadvantages of transcatheter versus aortic valve replacement for younger patients with aortic stenosis.
Topics Discussed:
• What factors are taken into account when considering lifetime management of aortic stenosis?
• Can valve in valve be performed inside of a transcatheter aortic valve replacement (TAVR) prosthesis?
• Who are the patients that are better served with surgical aortic valve replacement (SAVR)?
0:00 Managing Aortic Stenosis in Younger Patients
1:10 Defining the Younger Aortic Stenosis Patient
3:25 Evidence Comparing TAVR and Surgical Replacement
5:20 Bicuspid Valves and Emerging Clinical Trials
7:07 Planning for Future Valve-in-Valve Procedures
8:26 How Valve-in-Valve Replacement Works
10:54 When Surgery May Be the Better Choice
13:18 Choosing Between Tissue and Mechanical Valves
15:32 Trials and Guidelines for Younger Patients
16:55 Preserving Future Access to Coronary Arteries
18:20 Shared Decision-Making and Treatment Priorities
20:40 Continuing Cardiovascular Education at Mayo Clinic
