Uploaded June 2020 | Updated September 2026, 2 weeks ago
This video shows two different 3D views of TetX7 (green), a tetracycline-destroying enzyme that causes resistance to all tetracycline antibiotics (the small multicolored molecule in the center). Researchers at Washington University in St. Louis and the National Institutes of Health (NIH) have found that genes that confer the power to destroy tetracyclines are widespread in bacteria that live in the soil and on people. But the researchers have also created a chemical compound that shields tetracyclines from destruction. When the chemical compound was given in combination with tetracyclines, the antibiotics’ lethal effects were restored. The findings, available online in Communications Biology, indicate an emerging threat to one of the most widely used classes of antibiotics — but also a promising way to protect against that threat.
Video from Timothy Wencewicz/Washington University in St. Louis.
Read the news release: https://medicine.wustl.edu/news/antibiotic-destroying-genes-widespread-in-bacteria-in-soil-and-on-people/
This video shows two different 3D views of TetX7 (green), a tetracycline-destroying enzyme that causes resistance to all tetracycline antibiotics (the small multicolored molecule in the center). Researchers at Washington University in St. Louis and the National Institutes of Health (NIH) have found that genes that confer the power to destroy tetracyclines are widespread in bacteria that live in the soil and on people. But the researchers have also created a chemical compound that shields tetracyclines from destruction. When the chemical compound was given in combination with tetracyclines, the antibiotics’ lethal effects were restored. The findings, available online in Communications Biology, indicate an emerging threat to one of the most widely used classes of antibiotics — but also a promising way to protect against that threat.
Video from Timothy Wencewicz/Washington University in St. Louis.
Read the news release: https://medicine.wustl.edu/news/antibiotic-destroying-genes-widespread-in-bacteria-in-soil-and-on-people/
