An Introduction to Paired-Difference Procedures @jbstatistics
An Introduction to Paired-Difference Procedures  @jbstatistics
Uploaded June 2013 | Updated September 2026, 2 hours ago
An introduction to paired-difference procedures. I briefly discuss how paired-difference scenarios arise, and briefly outline how we can use the paired-difference t procedure to construct confidence intervals and carry out hypothesis tests. (Paired-difference procedures are sometimes referred to as matched-pairs procedures, depending on the setting.)

The alcohol/reaction time data is loosely based on information in:

Anderson et al. (2011). Functional Imaging of Cognitive Control During Acute
Alcohol Intoxication. Alcoholism: Clinical and Experimental Research, 35(1):156-165.

The identical twin-schizophrenia data is from:

Suddath et al. (1990). Anatomical abnormalities in the brains of monozygotic twins discordant for schizophrenia. New England Journal of Medicine, 322:789-794. Values used in this video are simulated values based on the summary statistics found in the paper.
An Introduction to Paired-Difference ProceduresInference for One Variance: An Example of a Confidence Interval and a Hypothesis TestYou sir, are no normal distributionInference for Two Variances: An Example of a Confidence Interval and a Hypothesis TestHypothesis Tests on One Mean:  t or z?An Example of a Paired-Difference t Test and Confidence IntervalHypothesis tests on one mean:  t test or z test?Hypothesis Testing in 17 SecondsSimple Linear Regression:  An ExampleLeverage and Influential Points in Simple Linear Regression1000 normal QQ plots in 30 minutes (n = 25, sampling from N(10,5^2))Pooled-Variance t Procedures: Investigating the Normality Assumption
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An Introduction to Paired-Difference Procedures

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