The Lancet | Amyloid accumulation in genetic forms of Alzheimer’s disease | The Lancet Neurology @TheLancetTV | Uploaded December 2022 | Updated October 2024, 2 hours ago.
In people carrying mutations for autosomal dominant Alzheimer’s disease, early amyloid accumulation occurs in the occipito-parietal cortices, closely followed by the frontal lobe and striatum. In people with Down syndrome, early amyloid accumulation occurs in the frontal region and striatum followed by regions in the parietal and temporal lobes.
Find out more at thelancet.com/journals/laneur/article/PIIS1474-4422(22)00408-2/fulltext and at thelancet.com/neurology
In people carrying mutations for autosomal dominant Alzheimer’s disease, early amyloid accumulation occurs in the occipito-parietal cortices, closely followed by the frontal lobe and striatum. In people with Down syndrome, early amyloid accumulation occurs in the frontal region and striatum followed by regions in the parietal and temporal lobes.
Find out more at thelancet.com/journals/laneur/article/PIIS1474-4422(22)00408-2/fulltext and at thelancet.com/neurology
