AlphaFold Tutorial @SirajRaval
AlphaFold Tutorial  @SirajRaval
Uploaded February 2020 | Updated September 2026, 2 weeks ago
AlphaFold is DeepMind's newly released State of the Art AI system for Protein Folding prediction. I tried it out myself and was able to predict and visualize several protein shapes, so in this episode I'm going to show you step by step how to install and run it on your computer too! And of course explain how it all works along the way. AlphaFold has applications in Health, Sustainability, and Materials Design, and IMHO is the most promising application of AI yet. Protein Folding is a nontrivial problem that has been worked on for decades by billion dollar pharmaceutical companies and research institutions. For DeepMind (an incumbent) to enter into a protein folding competition out of nowhere and win 1st place by out-predicting all of them is a HUGE deal. I really hope that I can convey how amazing AlphaFold is to you and that you're able to test it out yourself. Enjoy!

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DeepMind's AlphaFold Code:
github.com/deepmind/deepmind-research/tree/master/alphafold_casp13

Coding Challenge Instructions + submission form (Winners announced in next weeks video, Due date is Feb 9 at 12 PM PST):
https://forms.gle/cGgeW1DCLM7SFUBg9

My previous video on AlphaFold:
youtube.com/watch?v=cw6_OP5An8s

Are you a total beginner to machine learning? Watch this:
youtube.com/watch?v=Cr6VqTRO1v0

Learn Python:
youtube.com/watch?v=T5pRlIbr6gg

A more detailed video of AlphaFold by PipelineAI:
youtube.com/watch?v=EtUzTBWiZvE

Another detailed video of AlphaFold by IPD:
youtube.com/watch?v=uQ1uVbrIv-Q

The AlphaFold blogpost:
deepmind.com/blog/article/AlphaFold-Using-AI-for-scientific-discovery

An Dockerized implementation of AlphaFold by dellacortelab:
github.com/dellacortelab/prospr

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Credits:
DeepMind for the code
All images & GIFs used in this video were curated from across the Web via a public Google Image Search, I do not claim credit for creating any of them (except some memes)

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AlphaFold Tutorial

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