Uploaded May 2020 | Updated September 2026, 2 weeks ago
It's difficult to visually follow proteins in the mitochondria when they are also located in the cytosol of the cell. To overcome this problem, Marine Hemmerle and her colleagues developed a tool called "Big Mito Split-GFP" so that a protein is only visible when it is inside mitochondria. Watch Marine's video to learn how it works!
Marine Hemmerle is a PhD student in the lab DyPS (Dynamique et Plasticité des Synthétases) which is part of the IPCB (Institut de Physiologie et Chimie Biologique) at the University of Strasbourg (France).
It's difficult to visually follow proteins in the mitochondria when they are also located in the cytosol of the cell. To overcome this problem, Marine Hemmerle and her colleagues developed a tool called "Big Mito Split-GFP" so that a protein is only visible when it is inside mitochondria. Watch Marine's video to learn how it works!
Marine Hemmerle is a PhD student in the lab DyPS (Dynamique et Plasticité des Synthétases) which is part of the IPCB (Institut de Physiologie et Chimie Biologique) at the University of Strasbourg (France).
![Fluorescence: a tool to study molecular dynamics in biology
Fluorescence is used in Biology as a tool to study the internal of cells. In this video, Rémi Berthoz explains the basics of interactions between light and matter to schematically describe how fluorescent molecules can be used to monitor the flow of calcium ions in living cells. Watch Rémis video to learn more.
Rémi Berthoz is a student in the Cell Physics Master at the University of Strasbourg, France.
https://www.cellphysics-master.com
Related Resources :
Roger Y. Tsien et al. Nature Chemical Biology [Nat Chem Biol. 2007 Jul; 3(7): 423–431.].
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909385/ Fluorescence: a tool to study molecular dynamics in biology](https://i.ytimg.com/vi/KQhAS7OYu94/mqdefault.jpg)



![Gyrification: how the brain folds
Gyrification is the process occurring during the fetal stage that leads to the formation of the folds that appear on the surface of our brain. Because it can shed light on the functioning of the brain and some neurological diseases, understanding how and why these structures form is important. This led us to distinguish two complementary mechanisms that rule this phenomenon: biomechanics and genetically determined cellular processes. In this video, Thomas Perros summarizes these works and explanations to give a quick overview of the research on gyrification.
Thomas Perros is a student in the Cell Physics Master at the University of Strasbourg, France.
References:
[1]: Essen, D. A tension-based theory of morphogenesis and compact wiring in the central nervous system.https://www.nature.com/articles/385313a0
[2]: K roenke CD, Bayly PV. How Forces Fold the Cerebral Cortex. https://www.jneurosci.org/content/38/4/767
[3]: Van Essen DC. A 2020 view of tension-based cortical morphogenesis. https://pubmed.ncbi.nlm.nih.gov/33323481/
[4]: Tallinen T., Chung J., Rousseau F. et al. On the growth and form of cortical convolutions. https://www.nature.com/articles/nphys3632
[5]: Borrell V. How Cells Fold the Cerebral Cortex. https://www.jneurosci.org/content/38/4/776 Gyrification: how the brain folds](https://i.ytimg.com/vi/Mrm8a8wt9vQ/mqdefault.jpg)





