Uploaded June 2020 | Updated September 2026, 2 weeks ago

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"A common gut microbe secretes a carcinogen"
Our latest animation to help communicate the following paper published in Nature Journal by CleversLab: rdcu.be/b2f45 @hubrechtinstitute1313

From Hans Clevers tweet: "Our phD students Cayetano, Jens and Axel explain how a common E coli variant secretes a mutagen and induces a unique mutational signature upon chronic exposure inside gut #organoids. This signature also occurs in some colon cancers."
twitter.com/HansClevers/status/1233352114707058688

CONTENT
00:00 Gut bacteria
00:26 E. coli vs. pks+ E. coli
01:09 Antibiotics Treatment
01:18 Injection cycle
01:39 Clonal Expansion
01:58 Mutation Analysis
02:22 Mutation Induction


SOURCE
https://www.hubrecht.eu/
rdcu.be/b2f45

#biology #medical #microbiology

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