Uploaded May 2015 | Updated September 2026, 3 weeks ago
Here, we use UCSF Chimera to morph between two conformations of the Muscarinic Acetylcholine Receptor M2, program a random walk from one conformation to the next with a preference towards the inactive conformation when the ligand is unbound and towards the active conformation when the ligand binds. We add random walks to the atoms to simulate some intramolecular atomic Brownian motion.
Here, we use UCSF Chimera to morph between two conformations of the Muscarinic Acetylcholine Receptor M2, program a random walk from one conformation to the next with a preference towards the inactive conformation when the ligand is unbound and towards the active conformation when the ligand binds. We add random walks to the atoms to simulate some intramolecular atomic Brownian motion.
