A Man Found Blood In His Urine. This Is What Was Growing In His Kidneys. Chubbyemu 2021-08-18 | @HemeReview video ► youtu.be/j7WGP6sJBLkAnother case of RMC ► youtu.be/kyR6QNBBdSIPatient HC by Marcus Ellison Jr, Review by Dr. Pavlos MsaouelA Student Drank 2 Liters Fiber Supplement. This Is What Happened To His Organs. ► youtu.be/1MggKIfEld4A TikToker Chugged 8 Scoops PreWorkout Supplement. This Is What Happened To His Brain. ► youtu.be/MXoJghz4ctkThank you Dr Nizar Tannir, Dr Pavlos Msaouel, Cora and Herman Connor, and Dr Loren StaggProduction Assistant: Nick BrownIG me: instagram.com/chubbyemusTweet me: twitter.com/chubbyemuSearch for Chubbyemu on Snapchat, I have videos there 😌Music by @Lifeformed ► lifeformed.bandcamp.comSome images courtesy Getty ImagesRenal Medullary Carcinoma is a sickle cell related kidney malignancy that is usually diagnosed in young patients (median age at diagnosis 28 years old). It is considered a rare malignancy but likely afflicts more people than prior literature suggests given that review of that literature shows patients more in line with Renal Medullary Carcinoma rather than Collecting Duct Carcinoma. 3 year overall survival of RMC is 3%. Upfront chemotherapy then surgery is the suggested treatment. Response rate to platinum based chemotherapies, gemcitabine, doxorubicin is 29%.These cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.A Man Saw Blood In His Urine. This Is What Happened To His Kidney.References:Renal medullary carcinoma. The seventh sickle cell nephropathy. Am J Surg Pathol. 1995 Jan;19(1):1-11. pubmed.ncbi.nlm.nih.gov/7528470A Model Linking Sickle Cell Hemoglobinopathies and SMARCB1 Loss in Renal Medullary Carcinoma. Clin Cancer Res. 2018 May 1;24(9):2044-2049. pubmed.ncbi.nlm.nih.gov/29440190Updated Recommendations on the Diagnosis, Management, and Clinical Trial Eligibility Criteria for Patients With Renal Medullary Carcinoma. Clin Genitourin Cancer. 2019 Feb;17(1):1-6. pubmed.ncbi.nlm.nih.gov/30287223Five decades of urologic pathology: the accelerating expansion of knowledge in renal cell neoplasia. Hum Pathol. 2020 Jan;95:24-45. pubmed.ncbi.nlm.nih.gov/31655169GG Malouf, NM Tannir, P Rao, P Msaouel. Renal Medullary Carcinoma in Rare Kidney Tumors.Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma. Cancer Cell. 2020 May 11;37(5):720-734.e13. pubmed.ncbi.nlm.nih.gov/32359397The DNA sequence of human chromosome 22. Nature. 1999 Dec 2;402(6761):489-95. pubmed.ncbi.nlm.nih.gov/10591208High-intensity exercise is a risk factor for renal medullary carcinoma in individuals with sickle cell trait. Preprint. Atypical carcinoma of kidney originating from collecting duct epithelium. Urology. 1982 Jan;19(1):89-92. pubmed.ncbi.nlm.nih.gov/7058597Genes affecting the regulation of SUC2 gene expression by glucose repression in Saccharomyces cerevisiae. Genetics. 1984 Dec;108(4):845-58. pubmed.ncbi.nlm.nih.gov/6392017Purification and biochemical heterogeneity of the mammalian SWI-SNF complex. EMBO J. 1996 Oct 1; 15(19): 5370–5382. ncbi.nlm.nih.gov/pmc/articles/PMC452280
A Family Ate 1 Year Old Frozen Leftovers For Breakfast. This Is What Happened To Their Organs. Chubbyemu 2024-07-15 | Patient DC by Ray ZhengPatient MC by Alice CaiPatient BC by June Zhou (MS3 Shanghai Jiaotong University Medical School)Patient SC by Ivy ZhaoAce by AcePhysician by Dr. Yuqin CaoPhysician by Jason WongCoworker in shorts by Jason WhangGrip and Electric: David ZhangCasting: Q ChenFilmed at Xingxi Studios, ShanghaiMusic by @Lifeformed Additional music inspired by R PrinceIn-depth channel @HemeReview Secret channel @BigEmus Medicine ► youtube.com/playlist?list=PL26HeTCO57qcMQB6CrU6QRzEi9tt9l1FIA Foodborne Bongkrekic Acid Poisoning Incident — Heilongjiang Province, 2020. ncbi.nlm.nih.gov/pmc/articles/PMC8393157Bongkrekic Acid—a Review of a Lesser-Known Mitochondrial Toxin. ncbi.nlm.nih.gov/pmc/articles/PMC5440313Description of a Mass Poisoning in a Rural District in Mozambique: The First Documented Bongkrekic Acid Poisoning in Africa. pubmed.ncbi.nlm.nih.gov/29155976Bongkrekic acid poisoning: Severe liver function damage combined with multiple organ failure caused by eating spoiled food. sciencedirect.com/science/article/abs/pii/S1344622319302834CT diagnosis of toxic brain injury in cyanide poisoning: considerations for forensic medicine. ncbi.nlm.nih.gov/pmc/articles/PMC8332338Bongkrekic Acid and Burkholderia gladioli pathovar cocovenenans: Formidable Foe and Ascending Threat to Food Safety. ncbi.nlm.nih.gov/pmc/articles/PMC10648470Burkholderia gladioli and bongkrekic acid: An under-recognized foodborne poisoning outbreak.journalofinfection.com/article/S0163-4453(24)00116-6/fulltextATRACTYLOSIDE AND BONGKREKIC ACID SITES IN THE MITOCHONDRIAL ADP/ATP CARRIER PROTEIN.febs.onlinelibrary.wiley.com/doi/pdf/10.1016/0014-5793(81)80370-5The effect of lipids on bongkrekic (Bongkrek) acid toxin production by Burkholderia cocovenenans in coconut media. pubmed.ncbi.nlm.nih.gov/10435074Bongkrekic Acid – Uncommon but Fatal Toxin in Certain Foods. https://www.cfs.gov.hk/english/multimedia/multimedia_pub/multimedia_pub_fsf_214_02.htmlBurkholderia gladioli and bongkrekic acid: An under-recognized foodborne poisoning outbreak. journalofinfection.com/article/S0163-4453(24)00116-6/fulltextCT Scan courtesy of David Puyó, Radiopaedia.org, rID: 22276These cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.
A Woman Put Mercury Skin Cream On Her Face. This Is What Happened To Her Brain. Chubbyemu 2024-05-18 | Get Nebula using my link for 40% off an annual subscription: go.nebula.tv/chubbyemuWatch my exclusive video on Nebula: nebula.tv/videos/chubbyemu-a-man-inhaled-white-rocks-from-a-glass-pipe-this-is-what-happened-to-his-colonPatient DB by Dawn BradleyProducer: Dr Katherine JohnsIn-depth channel: @HemeReview Secret channel: @BigEmus Music by @Lifeformed ► lifeformed.bandcamp.comMedicine ► youtube.com/playlist?list=PL26HeTCO57qcMQB6CrU6QRzEi9tt9l1FIMercury and Minamata Disease: a Lesson from Japan | United Nations | UN in Action ► youtube.com/watch?v=80KJ9gqHrYoThese cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.References:MMWR 2019: Methylmercury Toxicity from a Skin Lightening Cream. cdc.gov/mmwr/volumes/68/wr/mm6850a4.htmMercury Poisoning Linked to Skin Products. fda.gov/consumers/consumer-updates/mercury-poisoning-linked-skin-productsClinical management of chronic mercury intoxication secondary to skin lightening products: A proposed algorithm. ncbi.nlm.nih.gov/pmc/articles/PMC8112557Minamata Disease The History and Measures. env.go.jp/en/chemi/hs/minamata2002/ch3.htmlMethylmercury poisoning: Long-term clinical, radiological, toxicological, and pathological studies of an affected family. psycnet.apa.org/record/1994-41898-001
A Man Had 2 Week Old Baked Potato For Dinner. This Is What Happened To His Brain. Chubbyemu 2024-04-13 | Use code EMU50 to get 50% OFF your first Factor box plus 20% off your next box at bit.ly/3PQu5C6! Thanks Factor for sponsoring this video!This case series in link belowPatient PD by Wolfgang NelsonMaster Brewer Inmate by Bryan AssataProduction Assistant: Tristyn SmithDirector of Photography: John MyungProducer: Dr Katherine JohnsIn-depth channel: @HemeReview Secret channel: @BigEmus Music by @Lifeformed ► lifeformed.bandcamp.comOther music inspired by R Prince, performed by Chubbyemume on @DaisyFoko's podcast youtu.be/1xrIF_wRRl4Medicine ► youtube.com/playlist?list=PL26HeTCO57qcMQB6CrU6QRzEi9tt9l1FITimestamp:0:00 A Prisoner Consumed 2 Week Old Baked Potato 🥔 For Dinner0:24 Introducing PD0:54 Good 🍊 fruit1:09 Getting 🤔 an idea1:45 haha juice go glug glug2:35 what's wrong sweaty, got a little 🤧 sneeze ?3:01 Guy: "Doc, can you take a closer look?" Doc: "no."3:26 Doc takes a closer look3:50 braaap4:25 pay attention to the symptoms together5:26 This is called Pace, the speed of onset and evolution of symptoms6:00 This is called Localization. Where are things going wrong?7:27 Too slow to be vascular etiology, too fast to be genetic or neoplastic8:34 Factor9:43 Eat potato🥔, brain 🧠 becomes potato. i dont make the rules around 🤷♂️ here11:00 Drink good12:21 mmm 😋 delicious13:23 Pace + Localization = Syndrome14:52 What do you think of this?These cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.References:CDC. Botulism from drinking prison-made illicit alcohol—Utah, 2011. MMWR 2012;61:782–4. cdc.gov/mmwr/preview/mmwrhtml/mm6139a2.htmWilliams BT et. al. Emergency department identification and critical care management of a Utah prison botulism outbreak. Ann Emerg Med. 2014 Jul;64(1):26-31. pubmed.ncbi.nlm.nih.gov/24331717Botulinum Toxin: Mechanism of Action and Clinical Use. openanesthesia.org/keywords/botulinum-toxin-mechanism-of-action-and-clinical-use
A Man Ate 120 Gummy Probiotics For Lunch. This Is What Happened To His Organs. Chubbyemu 2024-03-16 | Get a browser that’s better at everything, download Opera today! https://opr.as/Opera-browser-Chubbyemu. Thanks to Opera for sponsoring this video!In-depth Channel: @HemeReview Secret Channel: @BigEmus Gummy dosage forms are a nice innovation that can help with adherence, however should be approached with caution as the downside risk can be substantialMusic by @Lifeformed ► lifeformed.bandcamp.comAdditional Music by @T4N3 Medicine ► youtube.com/playlist?list=PL26HeTCO57qcMQB6CrU6QRzEi9tt9l1FIMy videos are on Nebula! Sign up to see extended cuts and exclusive videos: nebula.tv/chubbyemuTimestamp:0:00 A Man Ate 120 Gummy Probiotics 🦠 For Lunch0:29 29 seconds in and we're already 😏 here1:52 haha gummy probiotic 😋 go nom nom2:50 stomach 😞 hurt (but is it the stomach?)3:25 What's happening 😳 in 😳 his 😳 abdomen?4:51 There's a country of more than 1 billion people where dentistry is not separate from medicine. As insurance spirals out of control here, separating them makes us even less healthy.5:39 Another important clue7:04 Despite any memes, we've told you many details of this case to give you an idea of what's happening8:10 What 😳 is 😳 that??10:38 Sorry Bacteria 🦠 u can't 😩 be 😖 here11:24 So what 😲 exactly 😲 happened?11:58 I'm definitely not wearing a different suit than earlier in the video12:18 These are scarier than BC's case, but very rare and not likely to happen to you13:05 Greek Yogurt good13:19 The answer to this question might be yes. But ask your dentist for your particular case.14:08 Take only as directed. Do not exceed suggested dosage. That's the takeaway from this video. Take care of yourself 🙏 and be well.These cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. We do not give medical advice over the internet.References:Infective endocarditis and oral health—a Narrative Review. ncbi.nlm.nih.gov/pmc/articles/PMC8748486Lactobacillus Bacteremia and Probiotics: A Review. ncbi.nlm.nih.gov/pmc/articles/PMC10145752How safe is safe?--a case of Lactobacillus paracasei ssp. paracasei endocarditis and discussion of the safety of lactic acid bacteria.pubmed.ncbi.nlm.nih.gov/14606618Endocarditis by Lactobacillus rhamnosus due to yogurt ingestion? pubmed.ncbi.nlm.nih.gov/11669233Infective Endocarditis by Lactobacillus Species-A Narrative Reviewpubmed.ncbi.nlm.nih.gov/38247612Endocarditis Caused by Bacillus subtilis. academic.oup.com/ajcp/article-abstract/60/5/714/1770854?redirectedFrom=PDFFINAL RISK ASSESSMENT OF BACILLUS SUBTILIS. epa.gov/sites/default/files/2015-09/documents/fra009.pdfMedication Adherence: The Elephant in the Room. uspharmacist.com/article/medication-adherence-the-elephant-in-the-roomDefining “Candy-Like” Nonprescription Drug Products. fda.gov/media/172272/downloadNative Valve Endocarditis Secondary to Lactobacillus paracasei Bacteremia. consultant360.com/article/consultant360/native-valve-endocarditis-secondary-lactobacillus-paracasei-bacteremiaSurgical Treatment of Infective Endocarditis: When to Repair, When to Replace?consultqd.clevelandclinic.org/surgical-treatment-of-infective-endocarditis-when-to-repair-when-to-replaceInitial Presentation of Brucella Endocarditis in a Previously Healthy Eighteen-Year-Old Young Man. karger.com/crd/article-abstract/125/3/170/80052/Initial-Presentation-of-Brucella-Endocarditis-in-a?redirectedFrom=PDF
A Man Squatted 500 Pounds After Chugging 3 Energy Drinks And This Happened. Chubbyemu 2024-02-24 | Click my trainwell (formerly CoPilot) link go.trainwell.net/chubbyemu-cp to get 14 days FREE with your own personal trainer!In-depth channel: @HemeReview Secret channel: @BigEmus IG me: instagram.com/chubbyemusTweet me: twitter.com/chubbyemuMusic by @Lifeformed ► lifeformed.bandcamp.comOther music inspired by R Prince, Performed by ChubbyemuMedicine ► youtube.com/playlist?list=PL26HeTCO57qcMQB6CrU6QRzEi9tt9l1FITimestamp0:00 A Man Squatted 500 Pounds After Chugging 3 Energy Drinks0:24 Introducing 👨⚕️ LF0:56 Big Lifts1:28 LF has seen this before? But in others3:36 Thoughts about what could have happened7:44 Surgical 🔪 evaluation, and it was done...8:35 ...but something's wrong11:36 What risk factors predisposed LF to this?15:49 A proposal for the final treatment?These cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.References:Patient LF's vascular surgery is described in here: Open aortic septectomy for complicated type B aortic dissection. ncbi.nlm.nih.gov/pmc/articles/PMC9958067Acute Type A Aortic Dissection in a Young Weightlifter: A Case Study with an In-Depth Literature Review. swjpcc.com/critical-care/2020/8/7/acute-type-a-aortic-dissection-in-a-young-weightlifter-a-cas.htmlAortic Dissection in a Healthy Male Athlete: A Unique Case with Comprehensive Literature Review.pubmed.ncbi.nlm.nih.gov/27738530Management strategy for lower extremity malperfusion due to acute aortic dissection. sciencedirect.com/science/article/pii/S0741521421006728Aortic dissection is a disease of the vasa vasorum. ncbi.nlm.nih.gov/pmc/articles/PMC9390580Energy Drinks and the Risk of Cardiovascular Disease: A Review of Current Literature. ncbi.nlm.nih.gov/pmc/articles/PMC5501707The Valsalva And Stroke startingstrength.com/article/the_valsalva_and_strokeAcute Vascular Endothelial Changes Associated with Increased Blood Velocity Gradients.ahajournals.org/doi/10.1161/01.RES.22.2.165Turbulent Blood Flow in the Ascending Aorta of Humans with Normal and Diseased Aortic Valves. ahajournals.org/doi/pdf/10.1161/01.RES.39.1.58Turbulent Intensity of Blood Flow in the Healthy Aorta Increases With Dobutamine Stress and is Related to Cardiac Output. frontiersin.org/journals/physiology/articles/10.3389/fphys.2022.869701/fullBlood flow analysis of the aortic arch using computational fluid dynamics. academic.oup.com/ejcts/article/49/6/1578/2197449Caffeine for the Sustainment of Mental Task Performance: Formulations for Military Operations. ncbi.nlm.nih.gov/books/NBK223808
A Farmer Sprayed 1 Liter Pesticide Inbetween His Legs. This Is How His Organs Shut Down. Chubbyemu 2024-01-27 | Some details in paper different from video, link belowPatient PT by Wolfgang Nelson, PA Desiree Troy, Review Dr Katherine JohnsIn-depth channel: @HemeReview Secret channel: @BigEmus Music by @Lifeformed ► lifeformed.bandcamp.comMusic by @T4N3 ► soundcloud.com/t4n3Timestamps:0:00 A Farmer 👩🌾 Sprayed 1 Liter Pesticide Between His Legs0:30 A secret 🥶 encounter1:25 A wild idea 💡 appears3:10 Please 👩⚕️ stop 🛑 spraying this there4:27 A lab 🧪 test reveals 😲 something5:14 Good 🌱 plants 6:03 It was never 🤨 inside so what 😳 happened?7:05 Hard to breathe.. but why?9:32 How did it get in?11:30 It's circulating in his body, but where is it accumulating?Additional references:Based on publication [warning: explicit and difficult topics are discussed in the paper]: The toxicokinetics of acute paraquat poisoning in specific patients: a case series. journals.sagepub.com/doi/full/10.1177/03000605221122745Tox and Hound – Fellow Friday – Bipyridyl Herbicide Poisonings: Diquat and Paraquat. toxandhound.com/toxhound/ff-di-paraquatRegional variation in percutaneous penetration of 14C cortisol in man. pubmed.ncbi.nlm.nih.gov/6020682Polyamines in the lung: polyamine uptake and polyamine-linked pathological or toxicological conditions. journals.physiology.org/doi/full/10.1152/ajplung.2000.278.3.L417Prediction of outcome after paraquat poisoning by measurement of the plasma paraquat concentration. pubmed.ncbi.nlm.nih.gov/19228776/TEPA Finalizes New, Stronger Safety Measures for Pesticide Paraquat. epa.gov/pesticides/epa-finalizes-new-stronger-safety-measures-pesticide-paraquatBiochemical Mechanisms of Paraquat Toxicity. Anne P Autor. 1978.Vaginally Applied Diquat Intoxication. tandfonline.com/doi/abs/10.1081/CLT-100102470.Paraquat Poisoning. UpToDate.Paraquat and Diquat. Michael Eddleston. Critical Care Toxicology. 2017.Goldfrank's Toxicology.These cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.
A Husband Was Found With Another Woman. This Is What Was Done To His Organs. Chubbyemu 2023-12-18 | 🌏 Get NordVPN 2Y plan + 4 months free nordvpn.com/chubbyemu Risk-free with Nord’s 30-day money-back guarantee! ✌In order of appearance: RB by Wolfgang Nelson, Neighbor by Tristyn Smith, Woman by Star M, Zoe by Dawn Bradley, PA Tristyn SmithReviewer: Dr Katherine JohnsWatch this video ad-free on Nebula (40% off with my link!): go.nebula.tv/chubbyemuIn-depth channel: @HemeReview Secret channel: @BigEmus Music inspired by R. Prince. Arranged and performed by ChubbyemuOther Music by @Lifeformed ► lifeformed.bandcamp.comCT Head Case courtesy of Mohd Radhwan Bin Abidin, Radiopaedia.org, rID: 156961Timestamps:0:00 RB is a 42 year old man ☝️ presenting to the emergency room0:18 A history ⏰ of the history1:05 A wild thief 🥷 appears1:22 "I'll take care of u bebe"1:50 The only real way to butter 🧈 your bread2:18 Where we are 🚑 now3:37 "Not life threatening..." but is it really?4:11 This rapid pace becomes 🤨 concerning5:48 Something is very 😩 heavy6:44 A solid foundation 🌎 of understanding nature (as seen on Earth)9:01 An imposter 🥸 appears and the body cant discern 😳 the difference10:15 The mitochondria is no longer 😞 the powerhouse of the cell11:39 A connection to 😳 ancient esoteric 😳 knowledge12:44 Can iron and cyanide 😲 be involved in the help?13:54 Speaking of "life-threatening" and "energy" and "nerves," it brings us here now14:27 An incorrect assumption15:24 Enclosed herein is a case preserved into the written recordThese cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.References, starting with the case this video is based off of:Cerebrospinal fluid analysis in fatal thallium poisoning: evidence for delayed distribution into the central nervous system. pubmed.ncbi.nlm.nih.gov/15166769nytimes.com/2000/11/25/nyregion/police-charge-li-woman-in-poisoning.htmlAcute thallium poisoning: series of ten cases. pubmed.ncbi.nlm.nih.gov/21735311Case Files of the Medical Toxicology Fellowship at the Oregon Poison Center: Thallotoxicosis. ncbi.nlm.nih.gov/pmc/aRticles/PMC9198136Thallium toxicity and the role of Prussian blue in therapy. pubmed.ncbi.nlm.nih.gov/14579545Kinetic analysis of enzyme reactions. II. The potassium activation and calcium inhibition of pyruvic phosphoferase. pubmed.ncbi.nlm.nih.gov/13034826Pyruvate kinase revisited: the activating effect of K+. pubmed.ncbi.nlm.nih.gov/16147999Revised effective ionic radii and systematic studies of interatomic distances in halides and chalcogenides. scripts.iucr.org/cgi-bin/paper?S0567739476001551Francis Bacon - Experiments touching Sulphur and Mercury alchemywebsite.com/baconsul.htmlStructures of pyruvate kinases display evolutionarily divergent allosteric strategies. royalsocietypublishing.org/doi/10.1098/rsos.140120Sulfur mediated heavy metal biogeochemical cycles in coastal wetlands: From sediments, rhizosphere to vegetation. link.springer.com/article/10.1007/s11783-022-1523-x
A Man Ate Only Instant Noodles For 6 Months. This Is What Happened To His Organs. Chubbyemu 2023-12-02 | Gift hydration this holiday season with air up! Save up to 30% off: https://airup.link/Chubbyemu Thanks air up for sponsoring this video! Patient GN by Wolfgang Nelson, Sarah by Joanna Ferbrache, PA Tristyn SmithWatch this video ad-free on Nebula (40% off with my link!): go.nebula.tv/chubbyemuIn-depth channel: @HemeReview Secret channel: @BigEmus Music by @Lifeformed ► lifeformed.bandcamp.comAdditional Music by @T4N3 ► soundcloud.com/T4N3 Medicine ► youtube.com/playlist?list=PL26HeTCO57qcMQB6CrU6QRzEi9tt9l1FISome images by Getty ImagesTimestamp:0:00 A Man Ate 600 Pounds Ramen Over 6 Months0:18 He isn't pregnant, but he's here 😳 to deliver0:32 An important 🥶 history 1:16 Noodle 🍜 Good2:10 Is this stress 😳 or is something else 🤔 going on here3:06 I'd have my wife to drive me too instead of getting charged $9000 for 🚑 ambulance via high deductible unsurance3:39 Gut health 😌 very important5:06 Have you ever eaten noodles 🍜 so good that you look like this?6:35 haha water go 😳 glug glug8:00 What if we 😳 deamidated our glutamine residues 😳 after lunch9:28 Pack it up boys 👨⚕️ everything's cured10:00 noooo u cant just eat 4 pounds of instant noodles everyday10:45 I have no idea what my husband is doing but I think he's smuggling forbidden noodles into his workplace11:24 What 😲 are 😲 those12:54 New Oma13:41 U think 🤔 it's refractory but how can we be sure?14:43 This is what the noodles revealed was happening in his gutThese cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.References:Overview and pathogenesis of celiac disease. gastrojournal.org/article/S0016-5085(05)00177-0Celiac disease: a comprehensive current review. ncbi.nlm.nih.gov/pmc/articles/PMC6647104A case of celiac disease with hallucinations. ncbi.nlm.nih.gov/pmc/articles/PMC5765830Update on the Pathogenesis of Enteropathy-Associated T-Cell Lymphoma. ncbi.nlm.nih.gov/pmc/articles/PMC10453492Recent advances upper gastrointestinal lymphomas: molecular updates and diagnostic implications. pubmed.ncbi.nlm.nih.gov/33382495Hemophagocytic Lymphohistiocytosis in Refractory Celiac Disease Type II Transformed into Enteropathy-Associated T-Cell Lymphoma. acpjournals.org/doi/10.7326/aimcc.2022.0155#F1Enteropathy-type intestinal T-cell lymphoma: clinical features and treatment of 31 patients in a single center. pubmed.ncbi.nlm.nih.gov/10673521How I treat enteropathy-associated T-cell lymphoma. ashpublications.org/blood/article/119/11/2458/29625/How-I-treat-enteropathy-associated-T-cell-lymphomaTreatment response in enteropathy associated T-cell lymphoma; survival in a large multicenter cohort. pubmed.ncbi.nlm.nih.gov/25716069Enteropathy Associated T Cell Lymphoma – A Case Report of An Uncommon Extranodal T Cell Lymphoma. ncbi.nlm.nih.gov/pmc/articles/PMC4253173
A Bodybuilder Mistook An Aphrodisiac for Pre-Workout Supplement. This Is What Happened To His Brain. Chubbyemu 2023-11-04 | Get a 60-day free trial at shipstation.com/chubbyemu Thanks to ShipStation for sponsoring the show!Patient JC by Chad Collins, PA Tristyn Smith, Special Thanks to Jena MarxMusic by @Lifeformed ► lifeformed.bandcamp.comMore music by T4N3 ► soundcloud.com/t4n3Good Playlist ► youtube.com/playlist?list=PL26HeTCO57qcMQB6CrU6QRzEi9tt9l1FITimestamps:0:00 A Bodybuilder 💪 Mistook An Aphrodisiac 😳 for Pre-Workout Supplement0:22 JC was getting ready 🏋️ for a show0:55 A wild 😲 supplement appears1:35 Hey IRS 💵 we doing research 👨🔬 and development1:50 Good ☁️ powder2:16 haha preworkout 💪 go glug 😳 glug3:13 The emergency 🚑 room where we are now4:07 How does 🌳 do all of these??4:50 Rumors of this toxicity... are not exaggerated at all. It's not good.5:50 Neuro 🧠 transmitters gotta 😳 go 😲 fast6:48 Inside you(r autonomic nervous system) are 2 wolves (just kidding, they're more nervous systems)7:27 What happens 😳 here? 8:16 Alpha vs beta (not alpha male vs beta male)9:11 In the central nervous system9:47 Feedback 🛑 mechanism (in normal function)10:51 The CEO of systemic... response to adrenergic agents11:35 Multiple reports in existence12:02 "Just pull it out of his body bro"12:23 An Antidote 🐴 But How 🤔 Did We Find It?14:45 Yea lets not use that here, but we could use something else15:15 It takes 5 half lives to reach steady state, but Half Life 3 still isn't 😞 hereI don't think anyone reads anything that's written here. But here's for the metadata: this video is explicitly about adrenergic receptors. More specifically, the Alpha subtype, and even more specifically, Alpha 2 Adrenergic Receptors. This thing throws a massive curveball to learners in all medical disciplines because Alpha 2 agonism / antagonism are opposite of Alpha 1. The topic of these receptors can be a few weeks long in a Pharm course in Medical and Pharmacy schools, and that course would be dedicated specifically to cardiac pharmacology, so this is as much I can cover in an 18 minute video. There might be people who will go "nooooo u cant just say that about my tree bark supplement" but the point is and has always been to teach about the pharmacology, its mechanism and how the setting of excess changes the pharmacokinetics-- the agent serves as a means for me to teach that because it has that activity. If it didn't have that activity, I'd talk about something else that does in this setting. It's a fascinating molecule, like all natural products. If you don't need to ingest it, don't ingest it, but I trust you are well in your best capacity to make decisions for yourself.These cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.References:Acute neurotoxicity after yohimbine ingestion by a bodybuilder. pubmed.ncbi.nlm.nih.gov/19640235Yohimbine: a clinical review. pubmed.ncbi.nlm.nih.gov/11744068Alpha-2 Adrenoreceptor Antagonist Yohimbine Potentiates Consolidation of Conditioned Fear. academic.oup.com/ijnp/article/25/9/759/6617231Adrenergic receptors: structure and function. pubmed.ncbi.nlm.nih.gov/2164898Biopharmaceutics and metabolism of yohimbine in humans. pubmed.ncbi.nlm.nih.gov/10494000Yohimbe bark extract. ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/chem_background/exsumpdf/yohimbe_508.pdfYohimbine or NO-himbine? A Potentially Fatal Over-the-Counter Supplement. vumc.org/poison-control/toxicology-question-week/feb-15-2022-yohimbine-or-no-himbine-potentially-fatal-over-counter[PREPRINT] Xylazine is an agonist at kappa opioid receptors and exhibits sex-specific responses to naloxone administration. biorxiv.org/content/10.1101/2023.09.08.556914v1Xylazine, an Emerging Adulterant. acep.org/talem/newsroom/oct-2021/xylazine-an-emerging-adulterantYohimbine. pubmed.ncbi.nlm.nih.gov/4037464
A Mom Ate Chicken Burrito From A Suspicious Restaurant. This Is What Happened To Her Gut. Chubbyemu 2023-10-25 | Use code EMU50 to get 50% off your first Factor box at bit.ly/3qyFRHm!Patient DC by Kazia Steele, PA Tristyn Smith and Mike BurlingIn-depth channel: @HemeReview Secret Channel: @BigEmus Music by @Lifeformed ► lifeformed.bandcamp.comMedicine ► youtube.com/playlist?list=PL26HeTCO57qcMQB6CrU6QRzEi9tt9l1FISome images by Getty ImagesTimestamps:0:00 Good 🌯 Burrito0:31 Gotta 😳 go 😳 fast1:30 Where did it 🦷 go?2:24 Bacteria 🦠 good?3:42 Bacteria 🦠 good.4:47 The right bacteria 🦠 rly good5:46 What if the wrong species 😳 is growing?6:33 A wild headache 😩 appears7:16 Something was 🚽 different 7:51 Bacteria 🦠 coulda been good, but now what?9:42 Not the species 😨 you want...11:58 Banana 🍌 good13:43 A medicolegal 🩺 rationale16:26 The Swiss Cheese 🧀 Model (of errors like this one)16:56 I thought I was ok 😃 but now ???These cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.References:Clostridium difficile Toxins A and B: Insights into Pathogenic Properties and Extraintestinal Effects. ncbi.nlm.nih.gov/pmc/articles/PMC4885049C. diff survivor and advocate shares her story. blogs.cdc.gov/safehealthcare/c-diff-survivor-and-advocate-shares-her-story-2Aetiology of antimicrobial-agent-associated colitis pubmed.ncbi.nlm.nih.gov/85818Colitis associated with clindamycin therapy pubmed.ncbi.nlm.nih.gov/1202637Clostridioides difficile infection in adults: Treatment and prevention. UpToDate. Accessed 25 Oct 2023.Clostridioides difficile infection in adults: Clinical manifestations and diagnosis. UpToDate. Accessed 25 Oct 2023.Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients. science.org/doi/10.1126/science.aan4236Intestinal microbiota signatures of clinical response and immune-related adverse events in melanoma patients treated with anti-PD-1 nature.com/articles/s41591-022-01698-2. Gut microbiome is associated with the clinical response to anti-PD-1 based immunotherapy in hepatobiliary cancers. jitc.bmj.com/content/9/12/e003334Gut Microbiota in Anxiety and Depression: Unveiling the Relationships and Management Options. mdpi.com/1424-8247/16/4/565Clostridium difficile colitis following treatment with metronidazole and vancomycin. ncbi.nlm.nih.gov/pmc/articles/PMC2428710Durham Humphrey Amendment of 1951: gpo.gov/fdsys/pkg/STATUTE-65/pdf/STATUTE-65-Pg648.pdfIDSA Guidelines C Diff journals.lww.com/ajg/fulltext/2021/06000/acg_clinical_guidelines__prevention,_diagnosis,.12.aspx
This Quiz 😳 Answer Surprised Me 😲 #food #fish #foodie Chubbyemu 2023-09-27 | Me: Fish good 🐠Also Me: 🐟Scombroid 🐟 Poisoning 🐟
A Man Drank 7 Liters Soda Everyday For 10 Years. This Is What Happened To His Organs. Chubbyemu 2023-09-25 | Thanks to SoFi for sponsoring the video! Learn more about refinancing your student loans at: sofi.com/chubbyemuPatient BA by Bryan Assata; Hospitalist by Eric Nelson; Student by Dustin Petrillo; PA Desiree TroyIn-depth channel @HemeReview Secret channel @BigEmus Timestamps:0:00 Soda 🥤 good 1:06 Past medical 🩻 history2:26 Haha soda go glug glug2:49 One day he wasn't 😳 feeling well3:18 Chief 😩 complaint4:46 Human body ⚡️ electricity7:00 The P in SOAP (click like if you get this reference 👹)8:14 Haha soda go glug glug8:54 3 Gallons of WHAT is in his body??9:28 Haha urine 🤨 go glug glug10:45 The student 👨⚕️ sees 👀 something13:00 Soda 🥤 good, small science experiment better14:09 Stimulating by blocking inhibition16:21 Things we're actually concerned with in this setting19:22 Reasonably and sparingly is probably fineA Man Ate 8 Pound Hamburger in 30 Minutes. This Is How His Organs Shut Down. ► youtu.be/inXkUvHjhekMusic by @Lifeformed ► lifeformed.bandcamp.comMore music by T4N3 ► soundcloud.com/t4n3Medicine (Playlist) ► youtube.com/playlist?list=PL26HeTCO57qcMQB6CrU6QRzEi9tt9l1FISome images by Getty ImagesThese cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.References:Chronic hypokalemia due to excessive cola consumption: a case report. ncbi.nlm.nih.gov/pmc/articles/PMC2481241Caffeine-induced hypokalemia: a case report. bmcnephrol.biomedcentral.com/articles/10.1186/s12882-021-02465-0A cola-induced hypokalemic rhabdomyolysis with electromyographic evaluation: A case report. pubmed.ncbi.nlm.nih.gov/28321307Paroxysmal Paralytic Attacks Secondary to Excessive Cola Consumption. ncbi.nlm.nih.gov/pmc/articles/PMC4453309On the mechanism of rhabdomyolysis in potassium depletion. ncbi.nlm.nih.gov/pmc/articles/PMC292322Adenosine Receptors and the Kidney. ncbi.nlm.nih.gov/pmc/articles/PMC6027627Theophyllin As A Diuretic. pubmed.ncbi.nlm.nih.gov/18734158Comparative natriuretic and diuretic efficacy of theophylline ethylenediamine and of bendroflumethiazide during long-term treatment with the potent diuretic bumetanide. Permutation trial tests in patients with congestive heart failure. pubmed.ncbi.nlm.nih.gov/343509Soda and Other Beverages and the Risk of Kidney Stones. ncbi.nlm.nih.gov/pmc/articles/PMC3731916Changes in beverage intake between 1977 and 2001. pubmed.ncbi.nlm.nih.gov/15450632
Man Eats 8 Pound Burger: Report vs Video Differences Chubbyemu 2023-08-30 | Patient GF portrayed by @GugaFoods 🍔#science #burger
A Man Ate 8 Pound Burger In 30 Minutes. This Is What Happened To His Organs. ft @GugaFoods Chubbyemu 2023-08-27 | Use code EMU50 to get 50% off your first Factor box at bit.ly/3qyFRHm!Patient GF by @GugaFoods (see our collab! youtu.be/lsQzxB2mvbw)Cashier by Angel, Chef by Chef Howard (IG howardwight), Crowd by Team GugaThe case in publication: gastrojournal.org/article/S0016-5085(17)36093-6/fulltextIn-depth channel @HemeReview Secret channel @BigEmus Music by @Lifeformed ► lifeformed.bandcamp.comMedicine (playlist) ► youtube.com/playlist?list=PL26HeTCO57qcMQB6CrU6QRzEi9tt9l1FI0:00 Good 🍔 Burger 0:23 8 Hours ⏰ Earlier... (a history)1:57 At home now (review of symptoms)2:47 The emergency 🏥 room where we are now7:19 Competitive Eating8:55 An imaging study of top-level competitive eater9:42 Are there long-term consequences of competitive eating?11:39 What is clear, is....These cases are usually patients who I, or my colleagues have seen but this one was published in literature. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.References:The Perils of Competitive Speed Eating! gastrojournal.org/article/S0016-5085(17)36093-6/fulltextDon’t test for amylase in cases of suspected acute pancreatitis. Instead, test for lipase. aafp.org/pubs/afp/collections/choosing-wisely/317.htmlCompetitive consumption: Ten minutes. 20,000 calories. Long-term trouble? ncbi.nlm.nih.gov/pmc/articles/PMC3589306Competitive Speed Eating: Truth and Consequences. ajronline.org/doi/10.2214/AJR.07.2342They took blockbuster drugs for weight loss and diabetes. Now their stomachs are paralyzed. cnn.com/2023/07/25/health/weight-loss-diabetes-drugs-gastroparesis/index.html
A Farmer Mistakenly Drank His Own Herbicide. This Is What Happened To His Brain. Chubbyemu 2023-08-07 | Get Nebula using my link for 40% off an annual subscription: go.nebula.tv/chubbyemuSee the secret herbicide video on Nebula first here: nebula.tv/videos/chubbyemu-a-farmer-sprayed-1-liter-herbicide-between-his-legs-this-is-what-happened-to-his-organsPatient PT by Wolfgang Nelson, PA Desiree Troy, Review Dr Yue WuBehind the scenes: @BigEmus ► youtu.be/-cL7UkKkH1IIn-depth channel: @HemeReview IG me: instagram.com/chubbyemusTweet me: twitter.com/chubbyemuMusic inspired by R Price, Performed by ChubbyemuMusic by @Lifeformed ► lifeformed.bandcamp.comMedicine ► youtube.com/playlist?list=PL26HeTCO57qcMQB6CrU6QRzEi9tt9l1FIThese cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.References:Tox and Hound – Fellow Friday – Bipyridyl Herbicide Poisonings: Diquat and Paraquat. toxandhound.com/toxhound/ff-di-paraquatHigh-dose diquat poisoning: a case report. ncbi.nlm.nih.gov/pmc/articles/PMC8246526Urine sodium dithionite test: a useful clinical test for paraquat poisoning. journals.lww.com/jcsr/fulltext/2020/09030/urine_sodium_dithionite_test__a_useful_clinical.11.aspxHuman and experimental toxicology of diquat poisoning: Toxicokinetics, mechanisms of toxicity, clinical features, and treatment. pubmed.ncbi.nlm.nih.gov/29569487Case series: Diquat poisoning with acute kidney failure, myocardial damage, and rhabdomyolysis. frontiersin.org/articles/10.3389/fpubh.2022.991587/fullDiquat causes caspase-independent cell death in SH-SY5Y cells by production of ROS independently of mitochondria. ncbi.nlm.nih.gov/pmc/articles/PMC4572080Human and experimental toxicology of diquat poisoning: Toxicokinetics, mechanisms of toxicity, clinical features, and treatment. journals.sagepub.com/doi/10.1177/0960327118765330Ferroptosis: past, present and future. nature.com/articles/s41419-020-2298-2Where ferroptosis inhibitors and paraquat detoxification mechanisms intersect, exploring possible treatment strategies. pubmed.ncbi.nlm.nih.gov/32061663Methylene blue attenuates acute liver injury induced by paraquat in rats. sciencedirect.com/science/article/abs/pii/S1567576915002088Case report: Successful outcome of a young patient with rhabdomyolysis and shock caused by diquat poisoning. frontiersin.org/articles/10.3389/fmed.2023.1116912/fullBright Red Nuclei. https://n.neurology.org/content/62/4/619Biochemical Mechanisms of Paraquat Toxicity. Anne P Autor. 1978.Paraquat Poisoning. UpToDate.Paraquat and Diquat. Michael Eddleston. Critical Care Toxicology. 2017. doi.org/10.1007/978-3-319-17900-1_10Goldfrank's Toxicology.
A Man Put Cheese Making Ingredient In-between His Legs. This Is What Happened To His Soft Tissue. Chubbyemu 2023-07-11 | Adapted from this report: pubmed.ncbi.nlm.nih.gov/37184545In-depth channel: @HemeReview Secret channel: @BigEmus Music by @Lifeformed ► lifeformed.bandcamp.comMore music by T4N3 ►soundcloud.com/t4n3Medicine ► youtube.com/playlist?list=PL26HeTCO57qcMQB6CrU6QRzEi9tt9l1FIOne should always approach calcium with caution in the hospitalTimestamps:0:00 Important ⚠️ Notice0:13 A Man Put Cheese 🧀 Making Ingredient In-between His Legs1:40 Doing his own 🤔 research 2:43 Symptoms3:01 The emergency room 🚑 where we are now3:41 The cheese 🧀 and milk 🥛 saga 4:13 A mineral that can be an electrolyte5:12 This is called second messenger6:54 But this wouldn't be his only problem..8:18 A blood 🩸 test finds...10:33 A dearth of informationThese cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.References:Evaluation of single ... injection of calcium chloride for nonsurgical sterilization in adult albino rats. pubmed.ncbi.nlm.nih.gov/16472573Evaluation of single ... injection of calcium chloride for nonsurgical sterilization of male Black Bengal goats (Capra hircus): a dose-dependent study. pubmed.ncbi.nlm.nih.gov/157216611Regulation of cell death: the calcium–apoptosis link. nature.com/articles/nrm1150Intracellular Ca2+ sensing: role in calcium homeostasis and signaling. ncbi.nlm.nih.gov/pmc/articles/PMC5657234Skin and soft tissue necrosis from calcium chloride in a deicer jem-journal.com/article/S0736-4679(06)00633-0/fulltextRegulation of cell death: the calcium–apoptosis link. nature.com/articles/nrm1150Calcium Gluconate ncbi.nlm.nih.gov/books/NBK557463Calcium Chloride extravasation injury emergencymedicalminute.org/calcium-burnsMuscle cells need calcium ions. https://www.mpg.de/14590554/muscle-cells-need-calcium-ionsCalcium, mitochondria and cell metabolism: A functional triangle in bioenergetics. sciencedirect.com/science/article/pii/S0167488918304798Imaging of ... Masses: The Essentials. ncbi.nlm.nih.gov/books/NBK543804Severe Iatrogenic Calcinosis Cutis From Extravasated Calcium Gluconate. ncbi.nlm.nih.gov/pmc/articles/PMC7489317
A Man Ate Pork Tacos From An Illegal Food Truck. This Is What Happened To His Brain. Chubbyemu 2023-06-20 | Patient CD by Bryan Assata, Mustached Man by Wolfgang Nelson, Family Physician by Eric Nelson, Coworker by Marcus Ellison Jr, PA Tayler Miller, Special Thanks to Angie Burger!Music by @Lifeformed ► lifeformed.bandcamp.comMusic by T4N3 ► soundcloud.com/T4N3Some images by Getty ImagesVietnamese translation by Cao NguyênChinese translation by Jason Wong, 2BB, Marlon XuMedicine (playlist) ► youtube.com/playlist?list=PL26HeTCO57qcMQB6CrU6QRzEi9tt9l1FITimestamps:0:00 Taco 🌮 good0:25 A Man Ate Pork Tacos 😳 From An Illegal Food Truck2:42 A regular health 👨🏻⚕️ checkup3:12 Suspicious rumors of a 🚚 truck4:37 The emergency room 🚑 where we are now5:18 What can we rule out?6:31 Pigs 🐷 and humans 👨👩👧👦 throughout history7:37 Clean 😌 hygiene8:15 Factor9:17 An image 🧠 appears (with 4 stages)11:00 An important distinction13:55 Where did the meat 😳 come from?14:46 Food Truck 🚚 good15:20 OptionsThese cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.References:... from Cysticercosis, United States ncbi.nlm.nih.gov/pmc/articles/PMC2725874Parasites- Taeniasis. cdc.gov/parasites/taeniasis/biology.html#Case 34-2021: A 38-Year-Old Man with Altered Mental Status and New Onset of Seizures nejm.org/doi/full/10.1056/NEJMcpc2027080Imaging spectrum of neurocysticercosis. sciencedirect.com/science/article/pii/S2352621115000030Cysticercosis of the eye. ncbi.nlm.nih.gov/pmc/articles/PMC5554854Neurocysticercosis. radiopaedia.org/cases/neurocysticercosis-34Neurocysticercosis- Nodular Calcified. radiopaedia.org/cases/neurocysticercosis-nodular-calcifiedUnder seize: neurocysticercosis in an immigrant woman and review of a growing neglected disease. ncbi.nlm.nih.gov/pmc/articles/PMC4691866Diagnosis and Treatment of Neurocysticercosis: 2017 Clinical Practice Guidelines by the Infectious Diseases Society of America (IDSA) and the American Society of Tropical Medicine and Hygiene (ASTMH). ncbi.nlm.nih.gov/pmc/articles/PMC5928844Disseminated cysticercosis in a child: whole-body MR diagnosis with the use of parallel imaging.link.springer.com/article/10.1007/s00247-009-1438-8Pseudomuscular male with seizures: disseminated cysticercosis. semanticscholar.org/paper/Pseudomuscular-male-with-seizures%3A-disseminated-Goenka-Garg/3c547cf40956c0eff14217a576e74fc970221442Neurocysticercosis. medlink.com/articles/neurocysticercosisabqjournal.com/2543999/700-pounds-of-illegal-meat-cheese-seized-at-el-paso-border.htmldairyherd.com/news/education/meat-smuggling-threatens-us-livestock-biosecurityinsider.com/man-tried-smuggle-more-than-300-meat-across-us-border-2021-9businessinsider.com/us-customs-found-194-pounds-of-illegal-bologna-in-mans-car-2021-2
No Button Batteries In Your Stomach, Please 😩 Chubbyemu 2023-06-06 | Button Battery Ingestion Hotline: batteryingestionhotline.comMedicine ► youtube.com/playlist?list=PL26HeTCO57qcMQB6CrU6QRzEi9tt9l1FIIn-depth channel ► @HemeReview Secret channel ► @BigEmus IG me: instagram.com/chubbyemusTweet me: twitter.com/chubbyemu
Inhalant Brain Damage 🧠 Chubbyemu 2023-05-24 | Full @chubbyemu video: youtu.be/rQz-AoQx44YIn-depth channel @HemeReview Behind the Scenes @BigEmus References:Toluene Related Leukoencephalopathy radiopaedia.org/cases/toluene-related-leukoencephalopathy-1Cranial MR Findings in Chronic Toluene ncbi.nlm.nih.gov/pmc/articles/PMC8185739Neurotoxicity of solvents in brain pubmed.ncbi.nlm.nih.gov/21783541
What Was Growing In Her Body Was Said To Not Exist... Chubbyemu 2023-05-10 | Patient KC by Joanna Ferbrache, Cardiologist by Bryan Assata, Gynecologist by Star MEmergency Physician by Kazia Steele, Medical Oncologist by Eric Wolfgang NelsonReview (and KC's medical oncologist): Dr Pavlos MsaouelProduction Assistants: Erin Goodenough, Nick BrownKC's YouTube Channel ► @katiekickscancer_kidney Chromophobe and Oncocytic Tumor Alliance: kidneycoa.orgNational Institute of Health, Katie Coleman: ccr.cancer.gov/news/article/all-about-the-drive-a-rare-kidney-cancer-meets-its-match-at-nihKatie received her second opinion and treatment at MD Anderson Cancer Center and her surgery was done at the National Cancer Institute, where 2 other confirmed metastatic oncocytoma cases are documented. Her case report to publish in a medical journal is currently pending.Big Data Paradox@HemeReview in-depth with Dr Msaouel ► youtu.be/fuFzv1AwBKQCancer Patient Speaks Candidly With Her Physician ► youtu.be/Nddft_nc3Yc@BigEmus Behind The Scenes ► youtu.be/vdyP0YtGfTAKatie's Story (playlist) ► youtube.com/playlist?list=PL26HeTCO57qcQzfyqkC6RG2ECAxQgAjClJapanese Translation and Dub: Chihaya Hanai @rasha1m833 Japanese Voice KC: Kasumi SekiSpanish Translation and Dub: Cenzontle Voices, Inc CDMXSpanish Narration: Jerry MezaSpanish Voice KC: Jahel MorgaSpanish Review: Dr Araceli Morga VeraPortuguese Translation and Dub: Cenzontle Voices, Inc CDMXPortuguese Translation: Zyanya PoncePortuguese Narration: Santiago ÁlvarezPortuguese Voice KC: Gabriela PelliciaPortuguese Review: Lenin SagreroVietnamese translation and subtitles by Cao NguyênMusic by R Prince, performed by ChubbyemuAdditional Music by @Lifeformed ► lifeformed.bandcamp.comSome Images by Getty ImagesTimestamps:0:00 A Woman 💁♀️ Had A Headache Lasting 3 Days0:05 KC is a 28 year old woman ☝️ presenting 🚑 to the emergency room0:30 At the Urgent Care0:58 Over the next few months1:18 Abdominal pain2:06 The anticipation of an imaging 👀 modality3:03 Back in the 🚑 emergency room4:12 A phenomenon of nature5:06 An implication of heterogeneity5:43 The mitochondria is the powerhouse of the cell, but something's 😳 wrong6:41 Searching online cannot give you important contextual metadata7:59 How do you know your plan is the one for you?9:14 A powerful clinical reasoning tool10:53 If you hear hooves think horses 🐴 not 🦓 zebras, but play telephone and people may hear ????12:32 Presenting☝️ to the emergency 🚑 room13:04 This is called 'treatment resistance'These cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.References:Metastatic renal oncocytoma. ncbi.nlm.nih.gov/pmc/articles/PMC1955059Renal oncocytoma, yet another tumour that does not fit in the dualistic benign/malignant paradigm? ncbi.nlm.nih.gov/pmc/articles/PMC1955085Oncocytoma and metastatic potential: myth or reality? link.springer.com/article/10.1007/BF00327061Renal oncocytoma: clinicopathological study of 166 patients. J Urogenital Pathol 1991141–52.Classification of tumours. Pathology and genetics of tumours of the urinary system and male genital organs. Lyon: IARC Press, 2004Oncocytoma. pathologyoutlines.com/topic/kidneytumoroncocytoma.htmlChromophobe Kidney Cancer. pathologyoutlines.com/topic/kidneytumormalignantrccchromo.htmlImmunohistochemical analysis for cytokeratin 7, KIT, and PAX2: value in the differential diagnosis of chromophobe cell carcinoma.pubmed.ncbi.nlm.nih.gov/17210525The Big Data Paradox in Clinical Practice. tandfonline.com/doi/full/10.1080/07357907.2022.2084621A Causal Framework for Making Individualized Treatment Decisions in Oncology. mdpi.com/2072-6694/14/16/3923There is Individualized Treatment. Why Not Individualized Inference? arxiv.org/abs/1510.08539Causal inference and the data-fusion problem. pnas.org/doi/10.1073/pnas.1510507113
A Man Swallowed Wireless Earbud. This Is What Happened To His Esophagus. Chubbyemu 2023-04-22 | This is not the case that was in the news Patient HB portrayed by Eric Wolfgang Nelson. PA Erin GoodenoughUnited States has a Button Battery Ingestion Hotline poison.org/batterySpanish translation and dub by Cenzontle Voices, Inc CDMXSpanish Medical Advisor: Dr Araceli Morga VeraMusic by R Price, rearranged and performed by meOther Music by @Lifeformed ► lifeformed.bandcamp.comMedicine ► youtube.com/playlist?list=PL26HeTCO57qcMQB6CrU6QRzEi9tt9l1FISome images by Getty ImagesThese cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.References:Battery Ingestion Hotline (USA Poison Centers) batteryingestionhotline.comMechanism of Battery-Induced Injury. rmpds.org/mechanism-of-battery-induced-injury.htmlVascular Complications in Children Following Button Battery Ingestions: A Systematic Review.pubmed.ncbi.nlm.nih.gov/36032017Button battery ingestion: a review. pubmed.ncbi.nlm.nih.gov/2278232Obstruction of the GI tract. pubmed.ncbi.nlm.nih.gov/1718351Mechanical bowel obstruction: a tale of 2 eras. pubmed.ncbi.nlm.nih.gov/22351916Mechanical obstruction of the small bowel and colon. pubmed.ncbi.nlm.nih.gov/18387377Severe esophageal injuries caused by accidental button battery ingestion in children. pubmed.ncbi.nlm.nih.gov/25400396
Dont Bathe Your 4 Year Old In Alcohol To Reduce Fever Chubbyemu 2023-04-08 | Medicine ► youtube.com/playlist?list=PL26HeTCO57qcMQB6CrU6QRzEi9tt9l1FIReferences:4-year-old daughter admitted to ICU after parents wiped alcohol to reduce fever Report: b23.tv/pmqQjOrFever And Your Child, National Center on Early Childhood Health And Wellness. downloads.aap.org/DOCHW/FeverAndYourChild.pdfAlcohol-induced hypoglycemia and coma caused by alcohol sponging. pubmed.ncbi.nlm.nih.gov/5454799The Use of Folk Remedies Among Children in an Urban Black Community: Remedies for Fever, Colic, and Teething. web.archive.org/web/20070105020218/http://pediatrics.aappublications.org/cgi/content/full/115/3/e297
A Man Huffed Paint Thinner For 7 Hours And This Happened Chubbyemu 2023-03-31 | All references below. Inhalant misuse is well-documented to cause permanent damage to the body. The neurological damage can be acute, and continued misuse will progress to multi-organ damage. Sudden cardiac death is also known to happen with this misuse, along with a variety of additional problems.Music by @Lifeformed ► lifeformed.bandcamp.comMore music by T4N3 ► soundcloud.com/t4n3More music inspired by R PrinceMedicine ► youtube.com/playlist?list=PL26HeTCO57qcMQB6CrU6QRzEi9tt9l1FISome images by Getty ImagesToluene Toxic Leukoencephalopathy Image case courtesy of Dr Chee Kok Yoon, Radiopaedia.org, rID: 17082These cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.References:Syndromes of toluene sniffing in adults. Ann Intern Med. 1981;94:758-762.Glue-sniffing and distal renal tubular acidosis: sticking to the facts. pubmed.ncbi.nlm.nih.gov/1912400Laboratory approach for diagnosis of toluene-based inhalant abuse in a clinical setting. ncbi.nlm.nih.gov/pmc/articles/PMC4766772Neurotoxicity of solvents in brain of glue abusers. pubmed.ncbi.nlm.nih.gov/21783541Neural basis of inhalant abuse. pubmed.ncbi.nlm.nih.gov/9716942A rare but serious case of toluene-induced sudden sniffing death. sciencedirect.com/science/article/pii/S2211558715000953Hydrocarbon toxicity: A review. tandfonline.com/doi/full/10.3109/15563650.2014.923904Inhalant Misuse in children and adolescents. UpToDate. Accessed 28 Mar 2023.Effect of benzene, toluene, xylene on the .. quality of exposed workers. pubmed.ncbi.nlm.nih.gov/11601277Effects of pH on Potassium: New Explanations for Old Observations. ncbi.nlm.nih.gov/pmc/articles/PMC3231780THE EFFECT IN HUMANS OF EXTRACELLULAR pH CHANGE ON THE RELATIONSHIP BETWEEN SERUM POTASSIUM CONCENTRATION AND INTRACELLULAR POTASSIUM. ncbi.nlm.nih.gov/pmc/articles/PMC441665MR Imaging of "Spray Heads": Toluene Abuse via Aerosol Paint Inhalation ncbi.nlm.nih.gov/pmc/articles/PMC8332768/pdf/8237703.pdfReview of toluene action: clinical evidence, animal studies and molecular targets. ncbi.nlm.nih.gov/pmc/articles/PMC4211428On the mechanism of rhabdomyolysis in potassium depletion. ncbi.nlm.nih.gov/pmc/articles/PMC292322The Effects of Toluene on the Central Nervous System academic.oup.com/jnen/article/63/1/1/2916394Goldfrank’s Toxicologic Emergencies. 11th ed.
Farmers Accidental Cow Antibiotic Injection: Report vs Video Differences Chubbyemu 2023-03-12 | Full video: youtu.be/Al8BSBBurI4NIOSH Case report cdc.gov/niosh/face/stateface/ne/03ne004.htmlIn-depth Channel: @HemeReview Secret Channel: @BigEmus
Daylight Saving Bad 😡 Chubbyemu 2023-03-11 | A Grandpa Set His Clock Forward 1 Hour. youtu.be/bJ_ptg9GnDIReferences:michiganmedicine.org/health-lab/why-daylight-saving-time-could-increase-your-heart-attack-riskCircadian clocks and insulin resistance. Nat Rev Endocrinol. 2019 Feb;15(2):75-89. pubmed.ncbi.nlm.nih.gov/30531917Surgery: Circadian rhythms influence surgical outcomes. Nat Rev Cardiol. 2018 Jan;15(1):5.pubmed.ncbi.nlm.nih.gov/29143811A Review of Data of Findings on Night Shift Work and the Development of DM and CVD Events: a Synthesis of the Proposed Molecular Mechanisms. Curr Diab Rep. 2018; 18(12): 132. pubmed.ncbi.nlm.nih.gov/30343445Effects of season and climate on the first manic episode of bipolar affective disorder in Korea. Psychiatry Res . 2002 Dec 15;113(1-2):151-9. pubmed.ncbi.nlm.nih.gov/12467954washingtonian.com/2022/03/15/the-us-tried-permanent-daylight-saving-time-in-the-70s-people-hated-itsmithsonianmag.com/smart-news/what-happened-the-last-time-the-us-tried-to-make-daylight-saving-time-permanent-180979742
Achalasia Chubbyemu 2023-03-08 | Gas Station Nachos: youtu.be/KNb_MoqxA5oReferences:Treatment of Achalasia — From Whalebone to Botulinum Toxin. nejm.org/doi/full/10.1056/NEJM199503233321211Treating achalasia: from whalebone to laparoscope. pubmed.ncbi.nlm.nih.gov/9718057
A Farmer Injected Cow Antibiotic Into His Leg. This Is What Happened To His Organs. Chubbyemu 2023-03-04 | Report by NIOSH: cdc.gov/niosh/face/stateface/ne/03ne004.html Patient JC by Eric Wolfgang Nelson, some minor details of case changed due to logisticsThanks to the Bouckaert Family FarmMusic by R. Prince, rearrangedSome music by @Lifeformed ► lifeformed.bandcamp.comSpanish Translation and Dub: Cenzontle Voices Inc, CDMXMedical Reviewer: Dr Araceli Morga VeraPortuguese Translation and Dub: George FredericoChinese Translation and Subtitling: Jason Wong, Marlon X, KayaJapanese Translation and Dub: Chihaya Hanai @rasha1m833 In-depth channel: @HemeReview Secret channel: @BigEmus Medicine (playlist) ► youtube.com/playlist?list=PL26HeTCO57qcMQB6CrU6QRzEi9tt9l1FIThese cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.References:Second Case Report: cdc.gov/niosh/face/stateface/ne/04ne099.html Macrolide Antibiotics and the Risk of Cardiac Arrhythmias. ncbi.nlm.nih.gov/pmc/articles/PMC4061901 Toxicity of macrolide antibiotics on isolated heart mitochondria: a justification for their cardiotoxic adverse effect. tandfonline.com/doi/abs/10.3109/00498254.2015.1046975Cardiotoxicity of macrolides, ketolides and fluoroquinolones that prolong the QTc interval. pubmed.ncbi.nlm.nih.gov/12904146 Micotil Injection. journals.lww.com/em-news/fulltext/2005/08000/micotil_injection.40.aspx American Association of Poison Control Centers database characterization of human tilmicosin exposures, 2001–2005. ncbi.nlm.nih.gov/pmc/articles/PMC3550109 Analysis of reports of human exposure to Micotil 300 (tilmicosin injection). avmajournals.avma.org/view/journals/javma/229/11/javma.229.11.1737.xml Micotil Injection. content.elanco.com/en-us/product/beef/micotil/micotil-tilmicosin-injection Another tilmicosin case report: journals.lww.com/em-news/fulltext/2005/08000/micotil_injection.40.aspx ILE Failure in CCB Toxicity. casereports.bmj.com/content/15/1/e245711 Simplified Heart Muscle Cell Diagramkids.frontiersin.org/articles/10.3389/frym.2019.00065 Tutorial on Electrophysiology of the Heart. https://icerm.brown.edu/materials/Slides/tw-14-1/Tutorial_on_Electrophysiology_of_the_Heart_]_Sam_Dudley,_Brown_University.pdfMacrolides. https://tmedweb.tulane.edu/pharmwiki/doku.php/macrolides16S Ribosomal RNA Methylation: Emerging Resistance Mechanism against Aminoglycosides. academic.oup.com/cid/article/45/1/88/481913
Is Dont Break The Seal 🍻 Fact Or Myth? Chubbyemu 2023-02-15 | My in-depth channel @HemeReview References (there's way too many for a 53 second video)The diuretic action of alcohol and its relation to pituitrin. pubmed.ncbi.nlm.nih.gov/16994356MECHANISM OF DEHYDRATION FOLLOWING ALCOHOL INGESTION. pubmed.ncbi.nlm.nih.gov/14044808Alcohol diuresis. pubmed.ncbi.nlm.nih.gov/14894109The effect of alcohol on the renal excretion of water and electrolyte. pubmed.ncbi.nlm.nih.gov/15436874Effect of ethanol ingestion on plasma vasopressin and water balance in humans. pubmed.ncbi.nlm.nih.gov/7081477Medicine ► youtube.com/playlist?list=PL26HeTCO57qcMQB6CrU6QRzEi9tt9l1FI#shorts
A Man Drank Throat Numbing Spray While Eating Spicy Food. This Is What Happened To His Brain. Chubbyemu 2023-02-11 | Patient RJ by Jake Rattan, Friend 1 by Matt Hernandez, Food Enjoyer by Lexi Richmond, PA/Friend 4 by Luke MenziesMark Rober Hot Ones: youtube.com/watch?v=CJbP71RI-V4Peer Review: Dr Araceli Morga Vera, Dr Yue Wu, Dr Katherine JohnsSpanish translation and dub: Cenzontle Voices Inc, CDMXPortugese translation and dub: George FredericoMusic by @Lifeformed ► lifeformed.bandcamp.comIn-depth (podcast) channel @HemeReview Secret Channel @BigEmus Medicine ► youtube.com/playlist?list=PL26HeTCO57qcMQB6CrU6QRzEi9tt9l1FIThere's a secret version of this video in 8k: youtu.be/EA4y7gzbog0 the music levels were out of whack on that one so I elected to publish this one instead0:00 Throat Numbing Spray Label0:14 A Man Swallowed 1 Bottle Throat Numbing Spray While Eating Spicy Food2:00 haha spray go glug 😳 glug 3:29 The emergency room 🚑 where we are now4:10 Cyanosis and oxygen saturation5:05 Arterial blood gas vs oxygen saturation5:58 ...but something's wrong6:38 This brings us back to the spray...7:16 I promise you that stuff you learned in high school chemistry was worth it because it applies here10:07 What does the throat numbing spray have to do with this?12:10 ONOO😞- (Biochemical breakdown)14:49 Throat numbing spray misuse isn't new15:52 When you misuse the antidote and it becomes a poison itselfSome images by Getty ImagesThese cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.References: Benzocaine-induced Methemoglobinemia. ncbi.nlm.nih.gov/pmc/articles/PMC1586795Reported Adverse Event Cases of Methemoglobinemia Associated With Benzocaine Products. jamanetwork.com/journals/jamainternalmedicine/fullarticle/217060Safety Information on Benzocaine-Containing Products. fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/safety-information-benzocaine-containing-productsBenzocaine. cureus.com/articles/68795-a-rare-case-of-benzocaine-induced-methemoglobinemiaContinuous Methylene Blue Infusions for Treating Recurrent Methemoglobinemia. toxandhound.com/toxhound/refractory-methemoglobinemiaMethemoglobinemia emcrit.org/ibcc/methemoglobinemiaPulse Oximetry emcrit.org/pulmcrit/pulse-oximetryCharacterization of the methemoglobin forming metabolites of benzocaine and lidocaine. tandfonline.com/doi/abs/10.1080/00498254.2016.1196402Identification of N-Hydroxy-para-aminobenzoic acid in a cyanotic child after benzocaine exposure. pubmed.ncbi.nlm.nih.gov/25211007A mitochondrial superoxide theory for oxidative stress diseases and aging. ncbi.nlm.nih.gov/pmc/articles/PMC43066594.2 Oxygen Binding: chem.libretexts.org/Bookshelves/General_Chemistry/Book%3A_Structure_and_Reactivity_in_Organic_Biological_and_Inorganic_Chemistry_(Schaller)/V%3A__Reactivity_in_Organic_Biological_and_Inorganic_Chemistry_3/04%3A_Oxygen_Binding_and_Reduction/4.02%3A_Oxygen_BindingBenzocaine Label without Methemoglobinemia warning: https://fda.report/DailyMed/29890aa7-915a-46db-943d-a041d42f3637Acute Phenol Poisoning: jstor.org/stable/27720955Goldfrank's Toxicologic Emergencies 11th Edition TextMethemoglobinemia. UpToDate. Accessed 01 Feb 2023.
A Man Took 1176 Ibuprofen Tablets In A Month. This Is What Happened To His Kidneys. Chubbyemu 2023-01-19 | All references listed belowPortuguese translation and dub: George FredericoSpanish translation and dub: Cenzontle Voices, Inc. CDMXSpanish Medical Review: Dr Araceli Morga VeraMusic by R. Prince, rearrangedMusic by @Lifeformed lifeformed.bandcamp.comMusic by T4N3 soundcloud.com/t4n3Some images by Getty ImagesThese cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.References: Gastrointestinal injury associated with NSAID use: a case study and review of risk factors and preventative strategies. dovepress.com/gastrointestinal-injury-associated-with-nsaid-use-a-case-study-and-rev-peer-reviewed-fulltext-article-DHPSOesophageal perforation following ingestion of over-the-counter ibuprofen capsules. cambridge.org/core/journals/journal-of-laryngology-and-otology/article/abs/oesophageal-perforation-following-ingestion-of-overthecounter-ibuprofen-capsules/C46DB13A1F2DDAFD9073D8A6BB863691Esophageal ulcer induced by ibuprofen tablets. ncbi.nlm.nih.gov/pmc/articles/PMC5643597Kidney damage from non steroidal anti-inflammatory.. bpspubs.onlinelibrary.wiley.com/doi/epdf/10.1002/prp2.817Gastrointestinal injury associated with NSAID use: a case study and review of risk factors and preventative strategies. pubmed.ncbi.nlm.nih.gov/25653559Nonsteroidal antiinflammatory and acute renal failure in elderly persons. pubmed.ncbi.nlm.nih.gov/10707917 Many People Take Dangerously High Amounts of Ibuprofen. reuters.com/article/us-health-nsaids-overdosing/many-people-take-dangerously-high-amounts-of-ibuprofen-idUSKBN1FS336Does Ibuprofen Come in 1000 Tablet Bottles in America? Can the buyer finish it? zhihu.com/question/573412407NSAIDS: Acute Kidney Injury in UpToDate. Retrieved January 2023.
Getting Some Gastric Juices Flowing 🌊 Chubbyemu 2023-01-11 | Disorders of stomach secretion were revolutionized at the discovery of proton pump inhibitor therapy. For example, treatment of peptic ulcer disease before 1989 sometimes would be surgery. On a less severe scale, heartburn sometimes happen spontaneously, but is there something we could just change without any other intervention if it appears often? Maybe. PPI's profoundly increase stomach acid levels, so evidence for limiting proton pump activity as a way to control stomach acid is plausible, but we likely cannot and should not completely eliminate dietary potassium intake. However limiting it for a time may be help.References:Role of potassium in acid secretion ncbi.nlm.nih.gov/pmc/articles/PMC4622792Gastric acid level of humans must decrease in the future ncbi.nlm.nih.gov/pmc/articles/PMC7684463The impact of proton pump inhibitors on the human gastrointestinal microbiome. ncbi.nlm.nih.gov/pmc/articles/PMC4254461Diet and Gastroesophageal Reflux Disease asge.org/docs/default-source/about-asge/newsroom/doc-gerd_infographic_final.pdfThe effect and mechanism of action of capsaicin on gastric acid output.pubmed.ncbi.nlm.nih.gov/19296048The Physiology of the Gastric Parietal Cell. ncbi.nlm.nih.gov/pmc/articles/PMC7327232Substituted benzimidazoles inhibit gastric acid secretion by blocking (H+ + K+) ATPase.nature.com/articles/290159a0Priming the (Proton) Pump. ncbi.nlm.nih.gov/pmc/articles/PMC4844173A nonelectrogenic H+ pump in plasma membranes of hog stomach. jbc.org/article/S0021-9258(17)32907-1/pdf#shorts #stomach #gas #candy
A Man Drank Expired Coconut Water. This Is What Happened To His Brain. Chubbyemu 2022-12-13 | Based on case: ncbi.nlm.nih.gov/pmc/articles/PMC7774558Music by R. Prince, rearranged; References belowIn-depth channel: @HemeReview Secret channel: @BigEmus A Scientist Huffed Gas In A Balloon. ► youtu.be/LnkwxKHVLeUA Boy Ate 180 Gummy Melatonins For Lunch. ► youtu.be/nJR8Nfi8wg8A Man Dry Scooped 35000 Milligrams Caffeine. ► youtu.be/sylqJ0NEVJwMedicine (playlist) ► youtube.com/playlist?list=PL26HeTCO57qcMQB6CrU6QRzEi9tt9l1FIReferences: Fatal 3-Nitropropionic Acid Poisoning after Consuming Coconut Water. ncbi.nlm.nih.gov/pmc/articles/PMC7774558Structural Basis for Malfunction in Complex II. ncbi.nlm.nih.gov/pmc/articles/PMC3471735A pioneer study on human 3-nitropropionic acid intoxication: Contributions from metabolomics. analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/jat.42593-Nitropropionic acid-exogenous animal neurotoxin and possible human striatal toxin. pubmed.ncbi.nlm.nih.gov/17826163-Nitropropionic Acid - Exogenous Animal Neurotoxin and Possible Human Striatal Toxin. web.archive.org/web/20180728043418id_/cambridge.org/core/services/aop-cambridge-core/content/view/0F665A46A822D5149FDA63A410C448AE/S0317167100032212a.pdf/div-class-title-3-nitropropionic-acid-exogenous-animal-neurotoxin-and-possible-human-striatal-toxin-div.pdf3-nitropropionic acid is a suicide inhibitor of mitochondrial respiration that, upon oxidation by complex II, forms a covalent adduct with a catalytic base arginine in the active site of the enzyme ncbi.nlm.nih.gov/pmc/articles/PMC14828303-Nitropropionic acid animal model and Huntington' s disease. sciencedirect.com/science/article/abs/pii/S0149763496000279A phylogenetic re-evaluation of Arthrinium. doi:10.5598/imafungus.2013.04.01.13“Dazed and diffused”: making sense of diffusion abnormalities in neurologic pathologies ncbi.nlm.nih.gov/pmc/articles/PMC3856542Change in the Brain’s White Matter. ncbi.nlm.nih.gov/pmc/articles/PMC3201847Bongkrekic Acid—a Review of a Lesser-Known Mitochondrial Toxinncbi.nlm.nih.gov/pmc/articles/PMC5440313Burkholderia gladioli causes bacterial internal browning in sweetpotato of China. link.springer.com/article/10.1007/s13313-020-00691-yThese cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.
A Girl Ate 96 Gummy Edibles. This Is What Happened To Her Brain. Chubbyemu 2022-11-26 | All references are in the description belowPatient NP by Ceci, Tony by Wolfgang Nelson, Rebecca by Dawn Bradley, PA Erin GoodenoughUS FDA Alert: fda.gov/food/alerts-advisories-safety-information/fda-warns-consumers-about-accidental-ingestion-children-food-products-containing-thcMusic by @Lifeformed ► lifeformed.bandcamp.comIn-depth channel: @HemeReview Secret channel: @BigEmus This video was recorded and produced in English, and has been dubbed using an artificial voice via aloud.area120.google.com to increase accessibility. You can change the audio track language in the Settings menu.A Man Dry Scooped 35000 Milligrams Caffeine. This Is What Happened To His Organs: youtu.be/sylqJ0NEVJwA Boy Ate 180 Gummy Melatonins For Lunch. This Is What Happened To His Brain: youtu.be/nJR8Nfi8wg8Medicine (Playlist) ► youtube.com/playlist?list=PL26HeTCO57qcMQB6CrU6QRzEi9tt9l1FIIG me: instagram.com/chubbyemusTweet me: twitter.com/chubbyemuThese cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.References:Cannabis Edibles and Pediatric Toxicity Risk. uspharmacist.com/article/cannabis-edibles-and-pediatric-toxicity-riskPediatric Concerns Due to Expanded Cannabis Use: Unintended Consequences of Legalization.pubmed.ncbi.nlm.nih.gov/27139708Implications of Plasma Δ9-Tetrahydrocannabinol, 11-Hydroxy-THC, and 11-nor-9-Carboxy-THC Concentrations in Chronic. ncbi.nlm.nih.gov/pmc/articles/PMC3159863Promises and Challenges of Edibles. ncbi.nlm.nih.gov/pmc/articles/PMC5260817Innovative Therapeutics or Designer ncbi.nlm.nih.gov/pmc/articles/PMC3139381Trial of Cannabidiol for Drug-Resistant Seizures in the Dravet Syndrome. nejm.org/doi/10.1056/NEJMoa1611618Marijuana Equivalency in Portion and Dosage. researchgate.net/publication/316977045_Marijuana_Equivalency_in_Portion_and_DosageReview of delta-8-tetrahydrocannabinol (Δ8-THC): Comparative pharmacology with Δ9-THC bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15865Sedation and Acute Encephalopathy in a Pediatric Patient Following Ingestion of Delta-8-Tetrahydrocannabinol Gummies. ncbi.nlm.nih.gov/pmc/articles/PMC8594112Delta-8- and delta-9-tetrahydrocannabinol comparison in man by oral and intravenous administrationpubmed.ncbi.nlm.nih.gov/4698563An efficient new cannabinoid antiemetic in pediatric oncology pubmed.ncbi.nlm.nih.gov/7776837Cannabinoid Receptors in the Central Nervous System: Their Signaling and Roles in Disease. frontiersin.org/articles/10.3389/fncel.2016.00294/full
A Man Dry Scooped 35000 Milligrams Caffeine. This Is What Happened To His Organs. Chubbyemu 2022-10-24 | Caffeine in-depth @HemeReview ► youtu.be/rn-WLpa_nyQThis Is What Happened merch ► crowdmade.com/collections/chubbyemuPatient ET by Eric Wolfgang Nelson, PA Erin GoodenoughSpecial thanks to Jena Partida at The Training Ground and Steve ConnellyAnother caffeine approach ► youtu.be/wj_AOzSSDMMSecond channel: @HemeReview Secret channel: @BigEmus Music by @Lifeformed ► lifeformed.bandcamp.comMusic by @T4N3 ► soundcloud.com/t4n3Medicine ► youtube.com/playlist?list=PL26HeTCO57qcMQB6CrU6QRzEi9tt9l1FIIG me: instagram.com/chubbyemusFB me: facebook.com/chubbyemuTweet me: twitter.com/chubbyemuSome Images by Getty ImagesThese cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.References:Geib, AJ. (2016). Methylxanthines. In: Brent, J., Burkhart, K., Dargan, P., Hatten, B., Megarbane, B., Palmer, R. (eds) Critical Care Toxicology. Springer, Cham. doi.org/10.1007/978-3-319-20790-2_30-1. link.springer.com/referenceworkentry/10.1007/978-3-319-20790-2_30-1Ciszowski K, Biedron W, Gomolka E. Acute caffeine poisoning resulting in atrial fibrillation after guarana extract OD. Przegl Lek. 2014;71:495–8. pubmed.ncbi.nlm.nih.gov/25632790Wang HR, Woo YS, Bahk WM. Caffeine-induced psychiatric manifestations: a review. Int Clin Psychopharmacol. 2015;4:179–82. pubmed.ncbi.nlm.nih.gov/25856116Jabbar SB, Hanly MG. Fatal caffeine OD: a case report and review of literature. Am J Forensic Med Pathol. 2013;34:321–4. pubmed.ncbi.nlm.nih.gov/24196726McCleave DJ, Phillips PJ, Vedig AE. Compartmental shift of potassium – a result of sympathomimetic OD. Aust N Z J Med. 1978;8:180–3. pubmed.ncbi.nlm.nih.gov/277167Amitai Y, Lovejoy Jr FJ. Hypokalemia in acute theophylline poisoning. Am J Emerg Med. 1988;6:214–8. pubmed.ncbi.nlm.nih.gov/3370094Holstege CP, Hunter Y, Baer AB, et al. Massive caffeine OD requiring vasopressin infusion and hemodialysis. J Toxicol Clin Toxicol. 2003;41:1003–7. pubmed.ncbi.nlm.nih.gov/14705850High-Dose Insulin Euglycemic Therapy in the Treatment of a Massive Caffeine Overdose. pubmed.ncbi.nlm.nih.gov/32386647EAPCCT/AACT position paper: single-dose activated charcoal. Clin Toxicol. 2005;43:61–87. pubmed.ncbi.nlm.nih.gov/15822758Volume of Distribution. ncbi.nlm.nih.gov/books/NBK545280Intralipid and haemodialysis in caffeine overdose. pubmed.ncbi.nlm.nih.gov/32414776
A Man Cooked Chicken In Nighttime Flu Medicine. This Is What Happened To His Liver. Chubbyemu 2022-09-26 | Chubbyemu's in-depth channel ► @HemeReview My secret channel ► @BigEmus References in description belowIG me: instagram.com/chubbyemusTweet me: twitter.com/chubbyemuSearch for Chubbyemu on Snapchat, I have videos there 😌Some images by Getty ImagesMusic by @Lifeformed ► lifeformed.bandcamp.comAdditional music by T4N3 ► soundcloud.com/t4n3 Medicine ► youtube.com/playlist?list=PL26HeTCO57qcMQB6CrU6QRzEi9tt9l1FIThese cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet. No nighttime cold and flu medicine chicken 🙅♂️🙅♂️🙅♂️References:FDA Consumer Update A Recipe For Danger: Social Media Challenges Involving Medicines fda.gov/consumers/consumer-updates/recipe-danger-social-media-challenges-involving-medicinesAcetaminophen-Induced Hepatotoxicity: a Comprehensive Update pubmed.ncbi.nlm.nih.gov/27350943Acetaminophen-related hepatotoxicity. pubmed.ncbi.nlm.nih.gov/24099020Patient perception and knowledge of acetaminophen in a large family medicine service. pubmed.ncbi.nlm.nih.gov/24813653Acetaminophen (APAP) hepatotoxicity-Isn't it time for APAP to go away? pubmed.ncbi.nlm.nih.gov/28734939Acute acetaminophen toxicity in adults. pubmed.ncbi.nlm.nih.gov/31651762Acetaminophen (Paracetamol). D Nicholas Bateman. in Critical Care Toxicology. link.springer.com/referenceworkentry/10.1007/978-3-319-20790-2_108-2Acute liver necrosis following overdose of paracetamol. ncbi.nlm.nih.gov/pmc/articles/PMC1943529Acetaminophen and acetylcysteine dose and duration: past, present and future. pubmed.ncbi.nlm.nih.gov/22320209Management of paracetamol poisoning. doi.org/10.1136/bmj.d2218
A Wife Put Drain Cleaner In Husbands Coffee. This Is What Happened To His Stomach. Chubbyemu 2022-09-08 | Patient PB by Wolfgang Nelson, Katie by Amanda Love, PA Josh MannucciIn-depth channel: @HemeReview Secret third channel: @BigEmus Follow Wolfgang on IG instagram.com/wolfgangnelsonFollow Amanda on IG instagram.com/adthegIG me: instagram.com/chubbyemusTweet me: twitter.com/chubbyemuSearch for Chubbyemu on Snapchat, I have videos there 😌Music by @Lifeformed ► lifeformed.bandcamp.comMedicine ► youtube.com/playlist?list=PL26HeTCO57qcMQB6CrU6QRzEi9tt9l1FIThese cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.References:CT Esophagography for Evaluation of Esophageal Perforation. pubs.rsna.org/doi/full/10.1148/rg.2021200132Caustic ingestion: CT findings of esophageal injuries and thoracic complications. link.springer.com/article/10.1007/s10140-021-01918-1A case of severe corrosive esophagitis, gastritis, and liver necrosis caused by ingestion of methyl ethyl ketone peroxide. pdfs.semanticscholar.org/f87a/50e556d7b0bd7b412b00743ff60d6ad3e803.pdfCatastrophic Caustic Ingestion: A Case Report. sciendo.com/article/10.2478/jccm-2020-0017pubs.rsna.org/doi/10.1148/rg.327125035Caustic Ingestions. ncbi.nlm.nih.gov/books/NBK557442Calello, D.P. (2017). Caustics. In: , et al. Critical Care Toxicology. Springer, Cham. doi.org/10.1007/978-3-319-17900-1_90
A Scientist Huffed Gas In A Balloon. This Is What Happened To His Kidneys. Chubbyemu 2022-08-07 | All references including the book are in this description, see belowPatient MB portrayed by Abram Cutshall, Toast Scientist by Jake RattanSpecial thanks Westminster Christian AcademyProduction Assistant Jake RattanIn-depth channel @HemeReview Secret channel @BigEmus This video has been dubbed using an artificial voice via aloud.area120.google.com to increase accessibility. You can change the audio track language in the Settings menu.IG me: instagram.com/chubbyemusTweet me: twitter.com/chubbyemuMusic by @Lifeformed_ ► lifeformed.bandcamp.comMusic by T4N3 ► soundcloud.com/t4n3Medicine ► youtube.com/playlist?list=PL26HeTCO57qcMQB6CrU6QRzEi9tt9l1FIThese cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.References:Poisoning by arseniuretted hydrogen of hydrogen arsenide, its properties, sources, relations to scientific and industrial operations, symptoms, post-mortem appearances, treatment, and prevention. John Glaister. 1908. archive.org/details/poisoningbyarsen00glaiuoftTox and Hound Fellow Friday- Metal Hydries I. toxandhound.com/toxhound/ff-metal-hydridesSun HD, Ma L, Hu XC, Zhang TD. Treatment of acute promyelocytic leukemia by Ailing-1 therapy with use of syndrome differentiation of traditional Chinese medicine. Chin J Comb Trad Chin Med West Med 1992;12:170-171Complete Remission after Treatment of Acute Promyelocytic Leukemia with Arsenic Trioxide. nejm.org/doi/full/10.1056/NEJM199811053391901Acute on Chronic Arsenic Poisoning nejm.org/doi/full/10.1056/NEJMcps1716775Mechanisms of arsenic: https://sites.dartmouth.edu/toxmetal/arsenic/the-facts-on-arsenic/Severe acute arsine poisoning treated by plasma exchange. tandfonline.com/doi/full/10.1080/15563650701502675Interaction of Arsine with Hemoglobin in Arsine-Induced Hemolysis. academic.oup.com/toxsci/article/90/1/142/1692217Arsine toxicity: Chemical and mechanistic implications tandfonline.com/doi/abs/10.1080/15287399509532045 Arsenate replacing phosphate - alternative life chemistries and ion. ncbi.nlm.nih.gov/pmc/articles/PMC3070116Arsenic Binding to Proteins. ncbi.nlm.nih.gov/pmc/articles/PMC3797521A biography of arsenic and medicine hkmj.org/system/files/hkm1112p507.pdfMemorial Sloan Kettering Image by Kenneth C. Zirkel
A Boy Ate 180 Gummy Melatonins For Lunch. This Is What Happened To His Brain. Chubbyemu 2022-06-26 | Gummy yum yum 😋😋Chubbyemu's in-depth channel: @HemeReview References belowA Woman ate 23 Bananas After Fasting 7 Days: youtu.be/nQC_GDTNkQQMy third secret BTS channel @BigEmus IG me: instagram.com/chubbyemusTweet me: twitter.com/chubbyemuMusic by @Lifeformed ► lifeformed.bandcamp.comMore music by @T4N3 ► soundclound.com/t4n3 Some images by Getty ImagesThese cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.References:Pediatric Melatonin Ingestions — United States, 2012–2021. CDC Morbidity and Mortality Weekly Report / June 3, 2022 / 71(22);725–729.cdc.gov/mmwr/volumes/71/wr/mm7122a1.htmThe Importance of Melatonin Detection in Pediatric D ncbi.nlm.nih.gov/pmc/articles/PMC8351052Isolation of melatonin and 5-methoxyindole-3-acetic acid from bovine pineal glands. J Biol Chem. 1960 Jul;235:1992-7. pubmed.ncbi.nlm.nih.gov/14415935Physiology of the Pineal Gland and Melatonin. ncbi.nlm.nih.gov/books/NBK550972Total and Cause-Specific Mortality of U.S. Nurses Working Rotating Night Shifts. ajpmonline.org/article/S0749-3797%2814%2900623-0/fulltextTennessee Daycare Shut Down For Dosing Kids With Melatonin. crimeonline.com/2022/05/08/tennessee-daycare-shut-down-over-dosing-kids-with-melatoninPineal Calcification, Melatonin Production, Aging, Associated Health Consequences and Rejuvenation of the Pineal Gland. ncbi.nlm.nih.gov/pmc/articles/PMC6017004Annual reproductive rhythms in mammals: mechanisms of light synchronization. pubmed.ncbi.nlm.nih.gov/2934016NTP Nonneoplastic Lesion Atlas. ntp.niehs.nih.gov/nnl/endocrine/adrenal/cxatrophy/adrenal-gland-cortex-atrophy-pdf_508.pdf
A Boy Put On A Pair Of Suspicious Socks. This Is What Happened To His Kidneys. Chubbyemu 2022-06-08 | @HemeReview in-depth: youtu.be/aCSz6lKDJJEChubbyemu behind the scenes channel: @BigEmus These spiders are synanthropic so they live among us 😳Assistant camera: Jake RattanIG me: instagram.com/chubbyemusTweet me: twitter.com/chubbyemuMusic by @Lifeformed ► lifeformed.bandcamp.comAdditional music by @T4N3 ► soundcloud.com/t4n3Medicine (playlist) ► youtube.com/playlist?list=PL26HeTCO57qcMQB6CrU6QRzEi9tt9l1FIDaddy Longlegs by VengolisLoxosceles gaucho by HaliesSome images by Getty ImagesThese cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.References:CMS Malaque, RS Vetter, M Entres. Loxosceles spiders. Critical Care toxicology. link.springer.com/referenceworkentry/10.1007/978-3-319-17900-1_119Brown recluse spider (Loxosceles reclusa) envenomation leading to acute hemolytic anemia in six adolescents. ncbi.nlm.nih.gov/pmc/articles/PMC4902007Acute kidney injury and dermonecrosis after Loxosceles reclusa envenomation. ncbi.nlm.nih.gov/pmc/articles/PMC4119339Spider Bites: Part 1. lacerationrepair.com/wound-blog/spider-bitesBites of Brown Recluse Spiders and Suspected Necrotic Arachnidism. nejm.org/doi/full/10.1056/NEJMra041184CASE OF ARACHNOIDISM (SPIDER BITE). jamanetwork.com/journals/jama/article-abstract/265718Detection of Loxosceles species venom in dermal lesions: A comparison of 4 venom recovery methods.annemergmed.com/article/S0196-0644(02)04713-3/fulltextBrown spider (Loxosceles sp.) bite and COVID-19: A case report. sciencedirect.com/science/article/pii/S0041010122000861Loxosceles intermedia spider envenomation induces activation of an endogenous metalloproteinase, resulting in cleavage of glycophorins from the erythrocyte surface and facilitating complement-mediated lysis. sciencedirect.com/science/article/pii/S000649712036568X?via%3DihubNecrotic arachnidism. pubmed.ncbi.nlm.nih.gov/11260528Brown Recluse Michigan. ncbi.nlm.nih.gov/pmc/articles/PMC8384389Myth: Idiopathic wounds are often due to brown recluse or other spider bites throughout the United States ncbi.nlm.nih.gov/pmc/articles/PMC1071166Correspondance: Bites of the Brown Recluse Spider. nejm.org/doi/full/10.1056/nejm200505123521922Brown Recluse Pest Management Tips for The Spider That's Not As Common As You Think. entomologytoday.org/2018/01/29/brown-recluse-pest-management-tips-for-the-spider-thats-not-as-common-as-you-think/brown-recluse-range-mapThe Chilean Recluse. fdacs.gov/content/download/68159/file/Pest_Alert_-_Loxosceles_laeta,_The_Chilean_Recluse.pdfAn Infestation of 2,055 Brown Recluse Spiders (Araneae: Sicariidae) and No Envenomations in a Kansas Home: Implications for Bite Diagnoses in Nonendemic Areas. academic.oup.com/jme/article/39/6/948/862215
A Woman Nibbled On A Burger Sitting On Her Desk For Days. This Is What Happened To Her Kidneys. Chubbyemu 2022-05-02 | Based on a case from 2018, references to subject matter are belowIn-depth Channel @HemeReview Chubbyemu mug: http://crowdmade.com/collections/chubbyemuChubbyemu behind the scenes: @BigEmus Music by @Lifeformed ► lifeformed.bandcamp.comAdditional Music by T4N3 ► soundcloud.com/t4n3Medicine (playlist) ► youtube.com/playlist?list=PL26HeTCO57qcMQB6CrU6QRzEi9tt9l1FISecret Video 1 youtu.be/bq1kwlGhPyESecret Video 2 youtu.be/gBJiq3tMeBoUS CDC Presentation on the 1993 E coli O157:H7 Outbreak: youtube.com/watch?v=Ull53xGkRT4Patient KC portrayed by Joanna FerbracheDad by Keith NussbaumYoung KC by Olivia WalshSome images by Getty ImagesThese cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.References:A new route of transmission for Escherichia coli: infection from dry fermented salami. pubmed.ncbi.nlm.nih.gov/8712275Ricin and Shiga Toxins: Effects on Host Cell Signal Transduction ncbi.nlm.nih.gov/pmc/articles/PMC7120278Hemorrhagic colitis associated with a rare Escherichia coli serotype. pubmed.ncbi.nlm.nih.gov/6338386Isolation of Escherichia coli O157:H7 from dairy cattle associated with two cases of haemolytic uraemic syndrome. pubmed.ncbi.nlm.nih.gov/2877210Administration of Ricin Induces a Severe Inflammatory Response via Nonredundant Stimulation of ERK, JNK, and P38 MAPK and Provides a Mouse Model of Hemolytic Uremic Syndrome ncbi.nlm.nih.gov/pmc/articles/PMC1602309Entry of ricin and shiga toxin into cells: molecular mechanisms and medical perspectives. ncbi.nlm.nih.gov/pmc/articles/PMC305844Crystallographic refinement of ricin to 2.5. pubmed.ncbi.nlm.nih.gov/1881880Crystal structure of the holotoxin from Shigella dysenteriae at 2.5 A resolution. pubmed.ncbi.nlm.nih.gov/7656009Pathogenesis of Shiga Toxin-Associated Hemolytic Uremic Syndrome. nature.com/articles/pr2001160US Centers For Disease Control: cdc.gov/ecoli/outbreaks.html
A Boy Rubbed 1 Tube Pain Relief Cream Between His Legs. This Is What Happened To His Brain. Chubbyemu 2022-03-29 | @HemeReview In-depth video: youtu.be/TyIiM-02IqsPatient CG portrayed by Abram Cutshall, Jake by Matt Hernandez, Pizza Friend Isaah Williams, Friend 4 Jake RattanProduction Assistant: Jake RattanSecond in-depth channel: @HemeReview Third behind the scenes channel: @BigEmus A Student Ate Suspicious Leftovers ► youtu.be/EqHpnoV00j4A Boy Ate 25 Brownies in 1 Hour ► youtu.be/TMy0vJfKvzIIG me: instagram.com/chubbyemusTweet me: twitter.com/chubbyemuSearch for Chubbyemu on Snapchat, I have videos there 😌Music by @Lifeformed ► lifeformed.bandcamp.comMusic by @T4N3 ► soundcloud.com/t4n3Some images by Getty.These cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.References:Salicylate Toxicity from Exposure to a Methylsalicylate-Containing Rubefacient. ncbi.nlm.nih.gov/pmc/articles/PMC4786239Regional variation in percutaneous penetration of 14C cortisol in man. jidonline.org/article/S0022-202X(15)47268-9/pdfAnatomy and physiology of chronic s pain ncbi.nlm.nih.gov/pmc/articles/PMC5503924Ketone bodies: a review of physiology, pathophysiology and application of monitoring to diabetes. pubmed.ncbi.nlm.nih.gov/10634967 In DKA: acetoacetate (AcAc) and 3-beta-hydroxybutyrate (3HB), while acetone is the thirdISPAD Clinical Practice Consensus Guidelines 2018: DKA and the hyperglycemic hyperosmolar state. pubmed.ncbi.nlm.nih.gov/29900641Salicylates. Goldfrank, Lewis R, and Neal Flomenbaum. Goldfrank's Toxicologic Emergencies. New York: McGraw-Hill, 2006.Unconscious Uncoupling – Managing pH in Salicylate. Tox and Hound. toxandhound.com/toxhound/phinasaCounterproductive effects of sodium bicarbonate in DKA. pubmed.ncbi.nlm.nih.gov/8550770
A Student Ate Suspicious Leftovers For Lunch. This Is What Happened To His Limbs. Chubbyemu 2022-02-17 | Patient JC portrayed by Abram CutshallRoomate portrayed by Brandon GuzmanThis video is based on a case published in New England Journal of Medicine 2021 link belowMy second in-depth channel: @HemeReview My secret third behind the scenes channel: @BigEmus A Toddler Drank His Mom's Essential Oils. ► youtu.be/TZr0nt2hxbsA Woman Drank "35% Food Grade Hydrogen Peroxide." ► youtu.be/Eec98ie0PlgIG me: instagram.com/chubbyemusTweet me: twitter.com/chubbyemuSearch for Chubbyemu on Snapchat, I have videos there 😌Music by @Lifeformed ► lifeformed.bandcamp.comAdditional music by T4N3 ► soundcloud.com/t4n3Medicine ► youtube.com/playlist?list=PL26HeTCO57qcMQB6CrU6QRzEi9tt9l1FISome images by GettyPhoto from: doi.org/10.1038/s41467-018-06948-xMeningococcemia can be a life-threatening problemThese cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.References:Case 7-2021: A 19-Year-Old Man with Shock, Multiple Organ Failure, and Rash. nejm.org/doi/full/10.1056/NEJMcpc2027093Pathogenesis of meningococcal purpura fulminans academic.oup.com/femspd/article/75/3/ftx027/3064884Sepsis-associated disseminated intravascular coagulation and its differential diagnoses. jintensivecare.biomedcentral.com/articles/10.1186/s40560-019-0387-zPurpura fulminans: mechanism and management of dysregulated hemostasis. pubmed.ncbi.nlm.nih.gov/29157918Persistence of endothelial thrombomodulin in a patient with infectious purpura fulminans treated with protein C concentrate. pubmed.ncbi.nlm.nih.gov/30396911
A Boy Drank His Moms Essential Oils. This Is What Happened To His Brain. Chubbyemu 2022-01-25 | Please consult your local poison control center in cases like this 👶Megan and Patient BB portrayed by Megan Pulley and her sonReferences to subject matter and related cases belowA Woman Drank "35% Food Grade Hydrogen Peroxide." ► youtu.be/Eec98ie0PlgA Toddler Chewed Lead Paint Off His Toys. ► youtu.be/5qHxEjINCAgSecond Channel: @HemeReview Secret Channel: @BigEmus Music by @Lifeformed ► lifeformed.bandcamp.comIG me: instagram.com/chubbyemusTweet me: twitter.com/chubbyemuSearch for Chubbyemu on Snapchat, I have videos there 😌These cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.References:Regulation of Cell Volume in Health and Disease nejm.org/doi/full/10.1056/NEJM199511093331906Molecular Mechanisms of Ischemic Cerebral Edema: Role of Electroneutral Ion Transport journals.physiology.org/doi/pdf/10.1152/physiol.00015.2009Laryngeal oedema caused by accidental ingestion of Oil of Wintergreen. pubmed.ncbi.nlm.nih.gov/11335011Oil of Wintergreen. Annals of Emergency Medicine, Volume 31, Issue 6, 793 - 794.Measuring a toddler's mouthful. Annals of Emergency Medicine, Vol. 43, Issue 6, 792.Accidental Ingestion of Oil Of Wintergreen. The Journal of Family Practice, Vol 29, No 6, 1989.Managing pH in Salicylate. toxandhound.com/toxhound/phinasa
A Woman Drank 35% Food Grade Hydrogen Peroxide. This Is What Happened To Her Brain. Chubbyemu 2022-01-04 | I'd like some H2O too 😌😌😏😏😏😏😏😏😏😏😏😏Adult Patient KJ portrayed by Jennifer Wryn, PA Ben AnthonyReferences to subject matter and related cases belowA Student Ate 108 Gummy Antacids For Breakfast. ► youtu.be/sx93aUj4A_oA Mukbanger Ate 1 Gallon Pickles. ► youtu.be/gF69voHU_ysA Gamer Drank 12 Energy Drinks In 10 Minutes. ► youtu.be/tAtaIZD0EbsIG me: instagram.com/chubbyemusTweet me: twitter.com/chubbyemuSearch for Chubbyemu on Snapchat, I have videos there 😌Music by @Lifeformed ► lifeformed.bandcamp.comMedicine ► youtube.com/playlist?list=PL26HeTCO57qcMQB6CrU6QRzEi9tt9l1FISome images by GettyThese cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.References: Outcomes After High-Concentration Peroxide Ingestions. annemergmed.com/article/S0196-0644(16)31389-0/fulltextHydrogen Peroxide Poisoning—A Rare Cause of Portal Venous Gasncbi.nlm.nih.gov/pmc/articles/PMC8448209 Hydrogen peroxide poisoning pubmed.ncbi.nlm.nih.gov/15298493Massive hepatic gas embolism from a health food additive pubmed.ncbi.nlm.nih.gov/14980354Cerebral air gas embolism from concentrated hydrogen peroxide ingestion. tandfonline.com/doi/full/10.1080/15563650701725136Iatrogenic gas embolism following surgical lavage of a wound with hydrogen peroxide. pubmed.ncbi.nlm.nih.gov/10730173
When You Swallow Gum And This Happens To Your Intestines #shorts Chubbyemu 2021-12-06 | Fiber Supplement Bezoar ▶️ youtu.be/1MggKIfEld4Be Careful With Psyllium Husk ▶️ youtu.be/mPHXldh4_H4Chubbyemu shorts ▶️ youtu.be/fOPP9Qe10RgCheck out my other channels: @HemeReview @BigEmus References:Lessons Learned From a Rare Type of Gastric Bezoar somatopublications.com/lessons-learned-from-a-rare-type-of-gastric-bezoar.pdfChewing Gum Bezoars of the Gastrointestinal Tract publications.aap.org/pediatrics/article-abstract/102/2/e22/65601/Chewing-Gum-Bezoars-of-the-Gastrointestinal-Tract#shorts
A Student Ate 108 Gummy Antacids For Breakfast. This Is What Happened To Her Kidneys. Chubbyemu 2021-11-23 | Patient JT Portrayed by Joanna FerbracheMug is here 😉 ► crowdmade.com/collections/chubbyemuCase from 2019 seen by a colleague of mine on US east coast. See references below for more information on the disease state.My second channel where I go more in-depth ► @HemeReview Secret third channel ► @BigEmus IG me: instagram.com/chubbyemusTweet me: twitter.com/chubbyemuMusic by @Lifeformed ► lifeformed.bandcamp.comAdditional Music by T4N3 ► soundcloud.com/t4n3A Mukbanger Ate 1 Gallon Pickles. This Is What Happened To Her Brain. ► youtu.be/gF69voHU_ysA Gamer Drank 12 Energy Drinks In 10 Minutes. This Is What Happened To His Organs. ► youtu.be/tAtaIZD0EbsA Man Ate 100 Zinc Vitamin C Gummies Everyday. This Is What Happened To His Spinal Cord. ► youtu.be/oeyt2zVqCG8Flamin Hot Cheetos Pizza by Bianca Taylor Flamin Hot Cheetos Pizza by Kari SteeleFatimas Grill Flamin Hot Cheetos QuesadillaSome images licensed by Getty Images, Adobe StockThese cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.Peptic Ulcers need to be diagnosed by a clinician and appropriate treatment needs to be monitored. Psychiatric signs and symptoms from antibiotics are a rare reaction and should be monitored by a physician. This does not mean to avoid antibiotics, the benefit in the face of a bacterial infection generally outweighs the risk, at the discretion of the prescribing physician for the specific patient's illness. Milk Alkali Syndrome has been increasing in incidence over the last decade, despite H2 Antagonist and Proton Pump Inhibitor over-the-counter availability in the United States. This could be due to the common use of over-the-counter preparations of calcium for the prevention and treatment of osteoporosis in post-menopausal women. Calcium carbonate is also frequently prescribed to patients with chronic kidney disease for the prevention of secondary hyperparathyroidism. Milk-alkali syndrome now accounts for more than 10% of the cases of hypercalcemia and is the third most common cause of hypercalcemia in hospitalized patients. See references below for more information.References:Rare Causes of Hypercalcemia: 2021 Update. academic.oup.com/jcem/advance-article-abstract/doi/10.1210/clinem/dgab504/6317644?redirectedFrom=fulltextA review of antibiotics, d and the gut microbiome. sciencedirect.com/science/article/abs/pii/S0165178119303701Milk-Alkali Syndrome. ncbi.nlm.nih.gov/pmc/articles/PMC2664604/#R7Extreme metabolic alkalosis in intensive care. ncbi.nlm.nih.gov/pmc/articles/PMC2856150Second Messengers. ncbi.nlm.nih.gov/pmc/articles/PMC4968160Hypercalcemia. physio-pedia.com/Hypercalcemia#cite_note-p2-2Effects of Ca2+ and Mg2+ on Neuronal Excitability. http://pittmedneuro.com/ions.htmlCalcium block of Na+ channels and its effect on closing rate. ncbi.nlm.nih.gov/pmc/articles/PMC22436/#B6The dual role of calcium: Pore blocker and modulator of gating. ncbi.nlm.nih.gov/pmc/articles/PMC34267Nephrolithiasis secondary to inherited defects in the thick ascending loop of henle and connecting tubules. researchgate.net/figure/Schematic-representation-of-a-TALH-cell-NKCC2-Na-K-2Cl-cotransporter-ROMK-renal-outer_fig1_329073769
A Man Drank 6 Glowsticks For Dinner. This Is What Happened To His Stomach. Chubbyemu 2021-10-30 | In the US, call 1-800-222-1222 for State Poison Control poisonhelp.orgInternational Poison Centers contact https://apps.who.int/poisoncentres/Patient AC portrayed by Oscar Mansky and thanks to my friends at Nyoka Design Labs for the video suggestion!Get Chubbyemu Merch: crowdmade.com/collections/chubbyemuMy 2nd, in-depth YouTube Channel 👉 @HemeReview My Secret Third Channel 👉 @BigEmus IG me: instagram.com/chubbyemusTweet me: twitter.com/chubbyemuSearch for Chubbyemu on Snapchat, I have videos there 😌Music by @Lifeformed ► lifeformed.bandcamp.comEating 1 Gallon Pickles ► youtu.be/gF69voHU_ysMedicine (playlist) ► youtube.com/playlist?list=PL26HeTCO57qcMQB6CrU6QRzEi9tt9l1FISome images by Getty ImagesThese cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet. In context of this video, call the poison center if you have any doubts!!References:https://www.chop.edu/centers-programs/poison-control-center/glow-sticksillinoispoisoncenter.org/my-child-ate/glow-stickjamanetwork.com/journals/jamapediatrics/fullarticle/203843ncpoisoncontrol.org/types-of-poisons/common-poisons-at-home-and-work/glow-sticks
A Mukbanger Ate 1 Gallon Pickles. This Is What Happened To Her Brain. Chubbyemu 2021-10-04 | Chubbyemu merch ☕️ ► crowdmade.com/collections/chubbyemuPatient BT portrayed by Sheena Laird💜💕❤️🫀💋😌 Live, laugh, love 😌💋🫀❤️💕💜See my second channel @HemeReview for more in depth videosIG me: instagram.com/chubbyemusTweet me: twitter.com/chubbyemuSearch for Chubbyemu on Snapchat, I have videos there 😌1 Galllon Dill Pickle Jar (Inspired by Matt Stonie) ► youtu.be/SlXTNSAoSsA1 GALLON JAR of PICKLES ► youtu.be/yXVXgswb3qEA Woman Ate 23 Bananas After Fasting 7 Days ► youtu.be/nQC_GDTNkQQA Gamer Drank 12 Energy Drinks In 10 Minutes. ► youtu.be/tAtaIZD0EbsMusic by @Lifeformed ► lifeformed.bandcamp.comMore music by T4N3 ► soundcloud.com/t4n3Medicine (playlist) ► youtube.com/playlist?list=PL26HeTCO57qcMQB6CrU6QRzEi9tt9l1FIThese cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.References:Fatal Hypernatremia From Exogenous Salt Intake: Report of a Case and Review of the Literature. mayoclinicproceedings.org/article/S0025-6196(12)62194-6/fulltext this is not the case from this video. it's a review for students to understand the nature of hypernatremia, and how both excess exogenous sodium intake coupled with severe water loss contributes to symptomatic hypernatremia.Physiology, Gastrocolic Reflex ncbi.nlm.nih.gov/books/NBK549888Extra pickle reference health.clevelandclinic.org/6-health-benefits-of-drinking-pickle-juice
A Gamer Drank 12 Energy Drinks In 10 Minutes. This Is What Happened To His Organs. Chubbyemu 2021-09-13 | Mug is here 😳 ► crowdmade.com/collections/chubbyemu@HemeReview Weird Time When Energy Drinks Cured My Insomnia ► youtu.be/d_qKA6KTvs8Patient JS by Justin Silverman https://linktr.ee/justysilverman@MedlifeCrisis Energy Drink Video: youtu.be/na6tkBVVHCQSpanish Translation and dub: Cenzontle Voices, Inc. CDMXSpanish Medical Translation Reviewer: Dr Araceli Morga VeraMusic by @Lifeformed ► lifeformed.bandcamp.comAdditional Music by T4N3 ► soundcloud.com/t4n3Medicine ► youtube.com/playlist?list=PL26HeTCO57qcMQB6CrU6QRzEi9tt9l1FIIG me: instagram.com/chubbyemusTweet me: twitter.com/chubbyemuSearch for Chubbyemu on Snapchat, I have videos there 😌These cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.References:Energetic etiologies of acute pancreatitis: A report of five cases. ncbi.nlm.nih.gov/pmc/articles/PMC4644889Recurrent Acute Pancreatitis With Energy Drinks Consumption: Rare but Definite Association. eventscribe.com/2018/ACG/ajaxcalls/PosterInfo.asp?efp=RFNSWFFHSFY2NDI0&PosterID=162352&rnd=0.2438452A Rare Cause of Acute Pancreatitis. journals.lww.com/ajg/fulltext/2018/10001/a_rare_cause_of_acute_pancreatitis__1328.1328.aspxEnergy drink-induced cardiomyopathy casereports.bmj.com/content/14/4/e239370
