Uploaded April 2023 | Updated September 2026, 2 weeks ago
Viroporins are pore-forming peptides found in more than 30 viruses of relevance to human health and agriculture and are validated drug targets for the development of antiviral therapies. Because viroporins are challenging to study using traditional structural biology approaches, the development of viroporin inhibitors is hindered by the lack of high-resolution structures
Jiayu's project will use low-resolution data from impedance spectroscopy experiments with simulations to determine the structure of viroporin in membrane environments.
Viroporins are pore-forming peptides found in more than 30 viruses of relevance to human health and agriculture and are validated drug targets for the development of antiviral therapies. Because viroporins are challenging to study using traditional structural biology approaches, the development of viroporin inhibitors is hindered by the lack of high-resolution structures
Jiayu's project will use low-resolution data from impedance spectroscopy experiments with simulations to determine the structure of viroporin in membrane environments.
