Uploaded September 2026 | Updated September 2026, 3 hours ago
We dive into a science-heavy breakdown of vitamin C formulations, focusing on the recent updates to the gold-standard C E Ferulic serum. We explore the history of L-ascorbic acid efficacy studies dating back to the 1990s by Dr. Pinnell’s lab, highlighting the classic UV-induced erythema protocol used to validate antioxidant skin protection. Then, we analyze emerging clinical data around new CE Ferulic additions: carnosine and dandelion endophytol and discuss the available data to see if the chemists can figure out whether or not this is worth the Skinceuticals price tag.
00:00 | Intro!
03:15 | L-Ascorbic Acid: A Brief Review
12:48 | What is Dandelion Endophytol?
25:00 | Carnosine's Clinical UV MED Study
29:30 | Reviewing Carnosine's Clinical Testing
34:15 | The Challenges of Plant Extracts and Actives
38:30 | Chemists discuss CE Ferulic vs. CE Ferulic 2.0
41:45 | The Chemists' Feelings on Patents
We dive into a science-heavy breakdown of vitamin C formulations, focusing on the recent updates to the gold-standard C E Ferulic serum. We explore the history of L-ascorbic acid efficacy studies dating back to the 1990s by Dr. Pinnell’s lab, highlighting the classic UV-induced erythema protocol used to validate antioxidant skin protection. Then, we analyze emerging clinical data around new CE Ferulic additions: carnosine and dandelion endophytol and discuss the available data to see if the chemists can figure out whether or not this is worth the Skinceuticals price tag.
00:00 | Intro!
03:15 | L-Ascorbic Acid: A Brief Review
12:48 | What is Dandelion Endophytol?
25:00 | Carnosine's Clinical UV MED Study
29:30 | Reviewing Carnosine's Clinical Testing
34:15 | The Challenges of Plant Extracts and Actives
38:30 | Chemists discuss CE Ferulic vs. CE Ferulic 2.0
41:45 | The Chemists' Feelings on Patents
