Derek is a fitness educator, the entrepreneur behind More Plates More Dates, and an expert in exogenous molecules commonly used and misused by bodybuilders and athletes. In this episode, Derek returns to the podcast to explore the impact of exogenous molecules on male and female health. He covers testosterone, DHT, DHEA, progesterone, clomiphene (Clomid), hCG, and various peptides, alongside updates from the FDA affecting peptide use. Additionally, he addresses the recent hype around increasing muscle mass through myostatin inhibition via follistatin gene therapy and supplementation. Additionally, Derek discusses the various strategies that bodybuilders use for losing fat while preserving muscle, including insights on weight loss drugs.
We discuss: 0:00:00 - Intro 0:00:11 - Testosterone and DHT: mechanisms of action, regulation of muscle growth, and influence on male and female characteristics 0:07:38 - TRT in women: the complexities and potential risks associated with testosterone use in women 0:22:08 - DHEA supplementation: exploring the benefits and risks for women, and the differing effects on men vs. women 0:28:38 - The role of progesterone in both men and women, pros and cons of supplementation, the importance of tailored doses, and more 0:38:32 - Measuring levels of free testosterone 0:43:42 - The trend towards earlier interest in TRT, and the risks of underground sources of testosterone 0:48:00 - The complexities and considerations surrounding the use of Clomid, E-Clomid, and hCG in TRT 0:56:46 - Low testosterone: diagnosis, potential causes, treatment options, and other considerations 1:07:44 - Growth hormone-releasing peptides: rationale and implications of the recent FDA categorization as high-risk substances 1:20:00 - Follistatin gene therapy and myostatin inhibition for increasing muscle mass: the recent hype online, human and animal data, and the need for more research 1:39:53 - Simple tips for lowering calorie intake and losing fat 1:48:32 - Methods of sustainable fat loss with muscle preservation: insights gleaned from bodybuilders 2:05:11 - Could prolonged fasting impact testosterone levels? 2:06:56 - High-protein ice cream 2:12:36 - Exploring fat loss supplements and drugs: L-carnitine, yohimbine, and more 2:23:57 - Potential remedies for individuals experiencing metabolic dysfunction due to hypercortisolemia 2:31:17 - The cornerstones of body composition improvement remain nutrition and exercise, even in the presence of exogenous testosterone 2:36:12 - The importance of approaching health advice found online with a critical eye and a healthy dose of skepticism
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-use
Derek is a fitness educator, the entrepreneur behind More Plates More Dates, and an expert in exogenous molecules commonly used and misused by bodybuilders and athletes. In this episode, Derek returns to the podcast to explore the impact of exogenous molecules on male and female health. He covers testosterone, DHT, DHEA, progesterone, clomiphene (Clomid), hCG, and various peptides, alongside updates from the FDA affecting peptide use. Additionally, he addresses the recent hype around increasing muscle mass through myostatin inhibition via follistatin gene therapy and supplementation. Additionally, Derek discusses the various strategies that bodybuilders use for losing fat while preserving muscle, including insights on weight loss drugs.
We discuss: 0:00:00 - Intro 0:00:11 - Testosterone and DHT: mechanisms of action, regulation of muscle growth, and influence on male and female characteristics 0:07:38 - TRT in women: the complexities and potential risks associated with testosterone use in women 0:22:08 - DHEA supplementation: exploring the benefits and risks for women, and the differing effects on men vs. women 0:28:38 - The role of progesterone in both men and women, pros and cons of supplementation, the importance of tailored doses, and more 0:38:32 - Measuring levels of free testosterone 0:43:42 - The trend towards earlier interest in TRT, and the risks of underground sources of testosterone 0:48:00 - The complexities and considerations surrounding the use of Clomid, E-Clomid, and hCG in TRT 0:56:46 - Low testosterone: diagnosis, potential causes, treatment options, and other considerations 1:07:44 - Growth hormone-releasing peptides: rationale and implications of the recent FDA categorization as high-risk substances 1:20:00 - Follistatin gene therapy and myostatin inhibition for increasing muscle mass: the recent hype online, human and animal data, and the need for more research 1:39:53 - Simple tips for lowering calorie intake and losing fat 1:48:32 - Methods of sustainable fat loss with muscle preservation: insights gleaned from bodybuilders 2:05:11 - Could prolonged fasting impact testosterone levels? 2:06:56 - High-protein ice cream 2:12:36 - Exploring fat loss supplements and drugs: L-carnitine, yohimbine, and more 2:23:57 - Potential remedies for individuals experiencing metabolic dysfunction due to hypercortisolemia 2:31:17 - The cornerstones of body composition improvement remain nutrition and exercise, even in the presence of exogenous testosterone 2:36:12 - The importance of approaching health advice found online with a critical eye and a healthy dose of skepticism
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useWhat is muscle hypertrophy? | Peter Attia and Andy GalpinPeter Attia MD2024-03-24 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/4agioMq
This clip is from episode 239 ‒ The science of strength, muscle, and training for longevity with Andy Galpin, Ph.D. Andy Galpin is a professor of Kinesiology at California State University at Fullerton, where he studies muscle adaptation and applies his research to work with professional athletes.
In this clip, they discuss:
- When a person wants to have bigger muscles, what is happening at the cellular level with their muscle fibers? - Do different types of training increase sarcoplasmic versus contractile hypertrophy? - Why is it that a bodybuilder can have more muscle, yet they’re not stronger than a strong man or a weightlifter? - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useWhat factors influence your total daily energy expenditure? | Peter Attia and Layne NortonPeter Attia MD2024-03-23 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/3wYmFpL
This clip is from episode 205 - Energy balance, nutrition, & building muscle with Layne Norton, Ph.D. Layne Norton holds a Ph.D. in nutritional sciences and is a physique coach, natural bodybuilder, and previous guest on The Drive.
In this clip, they discuss:
- What is basal metabolic rate? - How can you test someones metabolic rate? - Why lean mass is so heavily correlated with total daily energy expenditure - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useDo portable VO2 testing devices actually work? | Peter Attia and Olav Aleksander BuPeter Attia MD2024-03-22 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/4cjnBF7
This clip is from episode 294 - Peak athletic performance: How to measure it and how to train for it from the coach of the most elite athletes on earth with Olav Aleksander Bu. Olav is an internationally renowned sports scientist acclaimed for his coaching prowess with elite athletes spanning a diverse range of sports disciplines.
In this clip, they discuss:
- Are there devices that you can buy at home to test and measure your VO2 max? - How accurate are portable VO2 max testing devices? - How do portable VO2 max tests work? - And more -------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useHow VO2 max is measured in the lab and why everyone should get theirs tested | Olav Aleksander BuPeter Attia MD2024-03-21 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/48R7JqA
This clip is from episode 294 - Peak athletic performance: How to measure it and how to train for it from the coach of the most elite athletes on earth with Olav Aleksander Bu. Olav is an internationally renowned sports scientist acclaimed for his coaching prowess with elite athletes spanning a diverse range of sports disciplines.
In this clip, they discuss:
- If Peter came to Olav’s lab to have his VO2 max measured, what would they do? - Why is oxygen consumption important? - Why having a higher VO2 max can help to fight illness - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useThe relationship between VO2 max, power output, and endurance | Peter Attia and Olav Aleksander BuPeter Attia MD2024-03-20 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/3TDc1xq
This clip is from episode 294 - Peak athletic performance: How to measure it and how to train for it from the coach of the most elite athletes on earth with Olav Aleksander Bu. Olav is an internationally renowned sports scientist acclaimed for his coaching prowess with elite athletes spanning a diverse range of sports disciplines.
In this clip, they discuss:
- Why VO2 max is not the greatest predictor of exceptional human performance - What is the best proxy surrogate metric for VO2 max when measuring for cylcing performance? - Is power at VO2 max a more insightful metric than VO2 max alone, for measuring athletic performance? - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useTraining interventions to increase VO2 max from the coach of elite athletes | Olav Aleksander BuPeter Attia MD2024-03-19 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/3Pnh3vB
This clip is from episode 294 - Peak athletic performance: How to measure it and how to train for it from the coach of the most elite athletes on earth with Olav Aleksander Bu. Olav is an internationally renowned sports scientist acclaimed for his coaching prowess with elite athletes spanning a diverse range of sports disciplines.
In this clip, they discuss:
- What standard Olav uses to train for increasing VO2 max? - The difference between VO2 max and aerobic capacity - The value of "exhaustion workouts in an exercise program" - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-use294 ‒ Peak athletic performance: How to measure it and how to train for itPeter Attia MD2024-03-18 | View show notes here: bit.ly/3Pq29od Become a member to receive exclusive content: peterattiamd.com/subscribe Sign up to receive Peter's email newsletter: peterattiamd.com/newsletter
Olav Aleksander Bu is an internationally renowned sports scientist acclaimed for his coaching prowess with elite athletes spanning a diverse range of sports disciplines. In this episode, Olav delves deep into the intricacies of VO2 max and its profound impact on performance. They explore the relationship between VO2 max and ATP production, energy efficiency, and power, as well as the impact of low-intensity training on VO2 max. The conversation extends to Olav’s experiences pushing the boundaries with high-performance athletes and the data driven interventions he uses to improve performance. They also dissect the role of lactate threshold, discuss other important metrics to track, and explore the exciting possibility of utilizing a portable VO2 testing device as a practical alternative to traditional lab-based assessments.
We discuss: 0:00:00 - Intro 0:01:29 - Olav’s background, expertise in exercise physiology, coaching experience, and interest in the extremes of human capability 0:08:03 - The processes of energy conversion within the human body and its implications for performance 0:19:50 - Improving movement efficiency, and the importance of mindfulness in training to optimize performance 0:36:34 - The relationship between VO2 max, power output, and endurance performance in different sporting contexts 0:47:36 - How VO2 max is measured in the lab, and why it’s a crucial predictor of both lifespan and quality of life 0:58:15 - Absolute vs relative VO2 max, the significance of functional threshold power in cycling, and the importance of longer duration tests for accurate assessments 1:10:35 - Portable VO2 testing devices as a practical alternative to lab-based tests 1:22:19 - The complexities of measuring ventilation and its impact on performance metrics like VO2 max and heart rate 1:30:54 - Training interventions to increase VO2 max, and factors that impact performance outcomes 1:41:15 - The respiratory exchange ratio (RER) and endurance sports, and how factors such as diet composition and exercise intensity influence RER values and performance 1:50:30 - Science-guided training for versatile athletes: maximizing VO2 max, power, torque, and cadence in cycling, and the importance of incorporating diverse stimuli to enhance performance 2:14:28 - Physiological limitations on VO2 max 2:19:07 - The different energy systems used during work, and other things to monitor like VCO2 and heart rate 2:24:03 - Lactate threshold and other metrics to guide your training 2:38:48 - Analysis of a lactate power curve: exploring lactate dynamics in endurance training and performance
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useWhy humans evolved to have better vision over smell | Peter Attia and Andrew HubermanPeter Attia MD2024-03-17 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/3vhz8UK
This clip is from episode 249 ‒ How the brain works, Andrew’s fascinating backstory, improving scientific literacy, and more with Andrew Huberman, Ph.D. Andrew Huberman is a Professor of Neurobiology at Stanford University and host of the Huberman Lab podcast.
In this clip, we discuss:
- Why did we trade out olfactory ability for color vision? - What is the definition of a pheromone? - Unique aspects of the human visual system - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useAre all calories created equal? | Peter Attia and Layne NortonPeter Attia MD2024-03-16 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/3V9iBNp
This clip is from episode 205 - Energy balance, nutrition, & building muscle with Layne Norton, Ph.D. Layne Norton holds a Ph.D. in nutritional sciences and is a physique coach, natural bodybuilder, and previous guest on The Drive.
In this clip, we discuss:
- Defining what a calorie is - How many calories are in each macronutrient - Does the gut microbiome play a roll in the absorption of energy from calories? - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useThe difference between fast-twitch and slow-twitch muscles | Peter Attia and Andy GalpinPeter Attia MD2024-03-15 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/3TxnCOs
This clip is from episode 239 ‒ The science of strength, muscle, and training for longevity with Andy Galpin, Ph.D. Andy Galpin is a professor of Kinesiology at California State University at Fullerton, where he studies muscle adaptation and applies his research to work with professional athletes.
In this clip, we discuss:
- Is there a force difference between fast and slow-twitch muscle fibers or just velocity difference? - Deep dive into what happens during a muscle contraction - How muscle fibers of animals differ from those of humans - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useAre high protein diets effective for fat loss? | Peter Attia and Don LaymanPeter Attia MD2024-03-14 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/3Iyih3i
This clip is from episode 224 ‒ Dietary protein: amount needed, ideal timing, quality, and more with Don Layman, Ph.D. Don Layman is a Professor of Food Science and Human Nutrition at the University of Illinois Urbana-Champaign.
In this clip, Don and Peter discuss:
- Peter's three strategies for approaching weight loss - How Don thinks about manipulating macros to achieve energy deficit - Why the high satiety of protein is very helpful for weight loss - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useWhy is progesterone so important for women? | Peter Attia and Derek MPMDPeter Attia MD2024-03-13 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/48v2EEj
This clip is from episode 291 ‒ The role of testosterone in males and females, performance-enhancing drugs, sustainable fat loss, supplements, and more with Derek, More Plates More Dates. Derek is a fitness educator, the entrepreneur behind More Plates More Dates, and an expert in exogenous molecules commonly used and misused by bodybuilders and athletes.
In this clip, Derek and Peter discuss:
- How Peter's thoughts on prescribing progesterone for women have changed over time - Is there a role for progesterone use by men? - Why Derek thinks progesterone is so important for women - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useMitigating age-related decline in strength and stability | Peter Attia and Mike JoynerPeter Attia MD2024-03-12 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/3TGVPeN
This clip is from episode 217 ‒ Exercise, VO2 max, and longevity with Mike Joyner, M.D. Mike Joyner is a physician-researcher and one of the world’s leading experts on human performance and exercise physiology.
In this clip, Mike and Peter discuss:
- How exercise can mitigate declines in physical ability as we age - The importance of stability for preventing falls in old age - How Peter approaches the Centenarian Decathlon - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useHigh-intensity interval training: benefits, risks, protocols, longevity impact (AMA 57 sneak peek)Peter Attia MD2024-03-11 | View show notes here: bit.ly/48KaNVl Become a member to receive exclusive content: peterattiamd.com/subscribe Sign up to receive Peter's email newsletter: peterattiamd.com/newsletter
In this “Ask Me Anything” (AMA) episode, Peter delves into the topic of high-intensity interval training (HIIT), starting with addressing some common misunderstandings around this type of exercise and breaking down what HIIT truly entails. He examines the correlation between HIIT and VO2 max, a vital metric for overall health and longevity, and describes the beneficial impact of HIIT on longevity when incorporated properly. Additionally, he emphasizes the importance of building a wide base of cardiovascular fitness, reveals the optimal protocols for incorporating HIIT into a balanced routine, and discusses the risk of injury and other potential drawbacks of HIIT.
In this sneak peek, we discuss: 00:00 - Intro 00:10 - Common questions about high-intensity interval training (HIIT) 02:04 - The origins of HIIT 04:55 - Defining HIIT training and differentiating it from sprint interval training (SIT) 14:02 - Why HIIT is often touted as a more efficient way to exercise
In the full episode, we also discuss: -Navigating the nuances of HIIT research: understanding limitations and the importance of a blended exercise routine; -The four pillars of exercise; -Using HIIT to improve VO2 max; -HIIT training for the untrained individual: impact on VO2 max and the interplay between exercise-induced adaptations and potential weight loss; -Sprint interval training (SIT) vs. HIIT: comparing the relative improvements in VO2 max and the impact of longer duration intervals; -Benefits and limitations of HIIT, drawbacks of overtraining with HIIT, and the importance of a diversified routine to increase total cardiorespiratory capacity; -HIIT protocols Peter recommends; -The risk of injury and other potential drawbacks of HIIT; -The importance of incorporating a balance of continuous moderate-intensity cardio and HIIT when aiming for longevity; and -More.
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useSimple metrics for identifying if youre training in Zone 2 | Peter Attia and Iñigo San-MillánPeter Attia MD2024-03-10 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/49OIq9A
This clip is from episode 201 - Deep dive back into Zone 2 Training with Iñigo San-Millán, Ph.D. Iñigo San-Millán is an internationally renowned applied physiologist and a previous guest on The Drive.
In this clip, Iñigo and Peter discuss:
- Metrics for characterizing Zone 2 training - How would Iñigo and Peter recommend you train in Zone 2? - How to use heart rate as a guide for determining if you're in Zone 2. - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useDo protein needs change as we age? | Peter Attia and Don LaymanPeter Attia MD2024-03-09 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/3V24Akm
This clip is from episode 224 ‒ Dietary protein: amount needed, ideal timing, quality, and more with Don Layman, Ph.D. Don Layman is a Professor of Food Science and Human Nutrition at the University of Illinois Urbana-Champaign.
In this clip, Don and Peter discuss:
- What do we know about the assimilation of amino acids into new muscle tissue across people of different ages? - How does the response to protein differ between 16 and 65 year olds. - Does muscle protein synthesis become less efficient as we age? - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useRisks and benefits of DHEA supplementation | Peter Attia & Derek MPMDPeter Attia MD2024-03-08 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/3T8QtIF
This clip is from episode 291 ‒ The role of testosterone in males and females, performance-enhancing drugs, sustainable fat loss, supplements, and more with Derek, More Plates More Dates. Derek is a fitness educator, the entrepreneur behind More Plates More Dates, and an expert in exogenous molecules commonly used and misused by bodybuilders and athletes.
In this clip, Derek and Peter discuss:
- Why are a lot of women asking to be put on DHEA? - What does the data say about DHEA's effect on hormones? - What are the possible side effects of using DHEA in women? - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useMaximize your VO2 max and fitness levels to live longer and healthier | Peter Attia and Mike JoynerPeter Attia MD2024-03-07 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/3uZE2pt
This clip is from episode 217 ‒ Exercise, VO2 max, and longevity with Mike Joyner, M.D. Mike Joyner is a physician-researcher and one of the world’s leading experts on human performance and exercise physiology.
In this clip, Mike and Peter discuss:
- How predictive is VO2 max of an individual’s mortality? - Why people that are quite fit continue to gain benefit in terms of all cause mortality - Why it is incredibly dangerous to be unfit cardiovascularly - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useThe most common injuries from rucking and how to avoid them | Peter Attia and Jason McCarthyPeter Attia MD2024-03-06 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/3V5xCzS
This clip is from episode 292 ‒ Rucking: benefits, gear, FAQs, and the journey from Special Forces to founding GORUCK, with Jason McCarthy. Jason is a former US Special Forces member and the founder of GORUCK, a company specializing in rucking equipment.
In this clip, Jason and Peter discuss:
- What are the most common rucking injuries? - Why it's important to start slow and light to avoid injury. - How often and how long should you ruck when you're first starting? - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useAnswering frequently asked questions about rucking | Peter Attia and Jason McCarthyPeter Attia MD2024-03-05 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/4c2BWpg
This clip is from episode 292 ‒ Rucking: benefits, gear, FAQs, and the journey from Special Forces to founding GORUCK, with Jason McCarthy. Jason is a former US Special Forces member and the founder of GORUCK, a company specializing in rucking equipment.
In this clip, Jason and Peter discuss:
- Do you have to buy a specific rucksack to start rucking? - How much weight should you start with? - What's the difference between a rucksack and a weight vest? - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-use292 ‒ Rucking: benefits, gear, FAQs, and the journey from Special Forces to founding GORUCKPeter Attia MD2024-03-04 | View show notes here: bit.ly/3Ipx2oI Become a member to receive exclusive content: peterattiamd.com/subscribe Sign up to receive Peter's email newsletter: peterattiamd.com/newsletter
Jason McCarthy is a former US Special Forces member and the founder of GORUCK, a company specializing in rucking equipment. In this episode, Jason recounts his journey from military service to navigating the challenging transition back into civilian life and ultimately embracing the mission of introducing rucking to the masses. Delving into the significance of rucking in military training and its applicability to the wider population, he discusses the mental and physical benefits of rucking as a mode of training, provides practical tips for beginners, and answers frequently asked questions about packs, weights, footwear, and more.
We discuss: 0:00:00 - Intro 0:01:21 - Jason’s upbringing and what inspired him to join the military 0:09:45 - Jason’s path to becoming a Green Beret, his calling to serve, and staying true to oneself 0:20:46 - About the Green Berets: their role in the military, unique abilities, missions, and more 0:26:31 - The mental and physical challenges of special forces training and selection 0:40:54 - Rucking challenges as a Green Beret 0:51:51 - How Jason trained in his off-time and stayed mentally prepared 0:57:27 - Jason’s difficult decision to leave the army, and the challenges many veterans face returning to civilian life 1:04:32 - Jason’s struggles after leaving the army: loss of identity, feelings of shame, and the how he overcame a period of despair 1:20:34 - The origin of GORUCK 1:36:06 - The GORUCK Challenge 1:48:50 - The company's evolution from event organizer to manufacturing specialist, spurred by the growing interest in rucking as a form of training 1:52:24 - FAQs about rucking: packs, weight, rucksack vs. weighted vest, chest straps, and more 2:06:52 - Commemorating Normandy: GORUCK's plans for the 80th anniversary of the Normandy landings 2:13:54 - Footwear for rucking, and how GORUCK got into the footwear business 2:22:37 - How to avoid the most common injuries from rucking, and the benefits of rucking for VO2 max, strength, and sleep quality 2:31:48 - Advice for using rucking as a mode of training, and the advantages of rucking over other forms of training
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useExploring fat loss supplements and drugs: L-carnitine, yohimbine, & more | Peter Attia & Derek MPMDPeter Attia MD2024-03-03 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/3OPui7J
This clip is from episode 291 ‒ The role of testosterone in males and females, performance-enhancing drugs, sustainable fat loss, supplements, and more with Derek, More Plates More Dates. Derek is a fitness educator, the entrepreneur behind More Plates More Dates, and an expert in exogenous molecules commonly used and misused by bodybuilders and athletes.
In this clip, Derek and Peter discuss:
- Why do people inject L-carnitine? - How effective is caffeine both in terms of its effect on appetite and potentially its effect on fat oxidation? - How does caffeine compare to ephedrine? - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-usePotential risks associated with TRT in women | Peter Attia and Derek MPMDPeter Attia MD2024-03-02 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/3T9AHgR
This clip is from episode 291 ‒ The role of testosterone in males and females, performance-enhancing drugs, sustainable fat loss, supplements, and more with Derek, More Plates More Dates. Derek is a fitness educator, the entrepreneur behind More Plates More Dates, and an expert in exogenous molecules commonly used and misused by bodybuilders and athletes.
In this clip, Derek and Peter discuss:
- How testosterone can cause masculinization in women - Why testosterone is an important hormone for women - What is Natesto and what are the pros and cons of using it? - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useSimple tips for lowering calorie intake and losing fat | Peter Attia and Derek MPMDPeter Attia MD2024-03-01 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/3OR0o36
This clip is from episode 291 ‒ The role of testosterone in males and females, performance-enhancing drugs, sustainable fat loss, supplements, and more with Derek, More Plates More Dates. Derek is a fitness educator, the entrepreneur behind More Plates More Dates, and an expert in exogenous molecules commonly used and misused by bodybuilders and athletes.
In this clip, Derek and Peter discuss:
- Low-hanging fruit for reducing caloric density - What are budget-friendly options for lean meat? - How to easily reduce your caloric intake by 500-600 calories - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useThe amazing potential to increase muscle mass via myostatin inhibition | Peter Attia and Derek MPMDPeter Attia MD2024-02-29 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/3IadR2d
This clip is from episode 291 ‒ The role of testosterone in males and females, performance-enhancing drugs, sustainable fat loss, supplements, and more with Derek, More Plates More Dates. Derek is a fitness educator, the entrepreneur behind More Plates More Dates, and an expert in exogenous molecules commonly used and misused by bodybuilders and athletes.
In this clip, Derek and Peter discuss:
- Gene therapy for follistatin - What does a myostatin knockout look like? - Is there a certified assay for measuring follistatin? - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useLow testosterone: diagnosis, potential causes, and treatment options | Peter Attia and Derek MPMDPeter Attia MD2024-02-28 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/49OxF7h
This clip is from episode 291 ‒ The role of testosterone in males and females, performance-enhancing drugs, sustainable fat loss, supplements, and more with Derek, More Plates More Dates. Derek is a fitness educator, the entrepreneur behind More Plates More Dates, and an expert in exogenous molecules commonly used and misused by bodybuilders and athletes.
In this clip, Derek and Peter discuss:
- What can impair pituitary function? - Are there guys that can recover after 10 years of TRT? - What can you do to maximize testosterone production? - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useHow to sustainably lose fat while maintaining muscle | Peter Attia and Derek MPMDPeter Attia MD2024-02-27 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/49KQFTZ
This clip is from episode 291 ‒ The role of testosterone in males and females, performance-enhancing drugs, sustainable fat loss, supplements, and more with Derek, More Plates More Dates. Derek is a fitness educator, the entrepreneur behind More Plates More Dates, and an expert in exogenous molecules commonly used and misused by bodybuilders and athletes.
In this clip, Derek and Peter discuss:
- Advice for someone who wants to lose 10lbs and keep it off - How to track your daily caloric intake - What is a sustainable caloric deficit? - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useThe major health benefits of light exercise | Peter Attia and Mike JoynerPeter Attia MD2024-02-25 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/49fRcNP
This clip is from episode 217 ‒ Exercise, VO2 max, and longevity with Mike Joyner, M.D. Mike Joyner is a physician-researcher and one of the world’s leading experts on human performance and exercise physiology.
In this clip, Mike and Peter discuss:
- The health benefits of walking - The importance of increasing daily movement - Why light exercise is beneficial for longevity - And more
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The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useWhat is Zone 2 and how is it measured? | Peter Attia and Iñigo San-MillánPeter Attia MD2024-02-24 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/3SIevc7
This clip is from episode 201 - Deep dive back into Zone 2 Training with Iñigo San-Millán, Ph.D. Iñigo San-Millán is an internationally renowned applied physiologist and a previous guest on The Drive.
In this clip, Iñigo and Peter discuss:
- How is Zone 2 measured? - How is fat oxidation measured? - What is Zone 2 at a cellular level? - And more
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The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useHow was the human genome sequenced? | Peter Attia and Alex AravanisPeter Attia MD2024-02-23 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/4bJMgTh
This clip is from episode 290 - Liquid biopsies for early cancer detection, the role of epigenetics in aging, and the more with Alex Aravanis, M.D., Ph.D. Alex Aravanis is a leader in research and development of technologies and clinical tests utilizing the latest tools in DNA analysis and data science.
In this clip, Alex and Peter discuss:
- How DNA sequencing has changed over time - When was the human genome first sequenced? - What is the cost of genome sequencing? - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useDo high saturated fat diets lead to heart disease? | Peter Attia and Don LaymanPeter Attia MD2024-02-22 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/3SZ1FaS
This clip is from episode 224 ‒ Dietary protein: amount needed, ideal timing, quality, and more with Don Layman, Ph.D. Don Layman is a Professor of Food Science and Human Nutrition at the University of Illinois Urbana-Champaign.
In this clip, Don and Peter discuss:
- How do dietary cholesterol, saturated fat, and overall fat effect human health? - What studies have been done to test the effects of saturated fat on heart health? - Is it more important to worry about saturated fat or overall calories consumed? - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useThe role of epigenetics in aging | Peter Attia and Alex AravanisPeter Attia MD2024-02-21 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/3I2WKiR
This clip is from episode 290 - Liquid biopsies for early cancer detection, the role of epigenetics in aging, and the more with Alex Aravanis, M.D., Ph.D. Alex Aravanis is a leader in research and development of technologies and clinical tests utilizing the latest tools in DNA analysis and data science.
In this clip, Alex and Peter discuss:
- A primer on methylation of our genome - Why epigenetic alterations are one of the 12 hallmarks of aging - Lifestyle factors that influence epigenetic changes - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useHow to increase your VO2 max | Peter Attia and Mike JoynerPeter Attia MD2024-02-20 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/3OLSjN2
This clip is from episode 217 ‒ Exercise, VO2 max, and longevity with Mike Joyner, M.D. Mike Joyner is a physician-researcher and one of the world’s leading experts on human performance and exercise physiology.
In this clip, Mike and Peter discuss:
- Peter's 4x4 protocol for increasing VO2 max - Mike Joyner's approach to increasing VO2 max - Exploring your limits with interval training - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-use290 ‒ Liquid biopsies for early cancer detection, the role of epigenetics in aging, and the morePeter Attia MD2024-02-19 | View show notes here: bit.ly/4bHY6wS Become a member to receive exclusive content: peterattiamd.com/subscribe Sign up to receive Peter's email newsletter: peterattiamd.com/newsletter
Alex Aravanis is a leader in research and development of technologies and clinical tests utilizing the latest tools in DNA analysis and data science. In this episode, Alex delves into two interconnected topics: liquid biopsies and epigenetics. He begins by tracing the trajectory of genome sequencing and tumor sequencing, setting the stage for a detailed exploration of liquid biopsies as an early cancer detection method. The discussion encompasses key concepts such as cell-free DNA, DNA methylation, sensitivity, specificity, and the predictive values associated with liquid biopsies. Transitioning to epigenetics, Alex examines the intricate interplay of DNA methylation and aging biology and explores the possibility of using cellular reprogramming to reverse epigenetic changes that occur with aging.
We discuss: 0:00:00 - Intro 0:00:08 - Alex’s background in applying engineering to problems in medicine 0:19:57 - A primer on human genetics, and the history and current landscape of DNA sequencing 0:24:05 - The advent and evolution of liquid biopsies for early detection of cancer 0:44:14 - The role of cell-free DNA in cancer detection: how incidental findings in non-invasive prenatal testing led to the development of liquid biopsies 0:51:05 - The development of a universal blood test for cancer detection and a discussion of specificity of tests 0:56:48 - Advancements in cell-free DNA analysis and development of a multi-cancer screening test at GRAIL 1:05:27 - DNA methylation explained 1:11:00 - Optimizing cancer detection with methylation analysis of cfDNA in small blood samples 1:17:22 - The importance of understanding sensitivity, specificity, positive predictive value, and negative predictive value in cancer screening 1:32:57 - The performance of the GRAIL Galleri test and its ability to detect various types and stages of cancer 1:41:05 - Do early cancer detection methods, like liquid biopsies, translate to improvement in overall survival? 1:54:45 - The role of epigenetics in aging 2:01:58 - How cell-free DNA methylation patterns can help identify a cancer’s tissue of origin 2:09:48 - Cellular and epigenetic reprogramming and other exciting work in the field of aging
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useHow your internal narrative affects your relationships with others | Peter Attia and Esther PerelPeter Attia MD2024-02-18 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/3OG8VWp
This clip is from episode 172 ‒ Trauma, how narratives shape our worldview, and accepting uncomfortable emotions with Esther Perel. Esther Perel is a psychotherapist and New York Times bestselling author who is an expert on modern relationships.
In this clip, we discuss:
- Developing and changing narratives about our lives - The two most fundamental narratives rooted in trauma - The importance of fostering relationships with others to better know oneself - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useKeeping your spine healthy from a young age | Peter Attia and Stuart McGillPeter Attia MD2024-02-17 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/3w9pJyG
This clip is from episode 287 - Lower back pain: causes, treatment, and prevention of lower back injuries and pain with Stuart McGill, Ph.D. Stuart McGill is a distinguished professor emeritus at the University of Waterloo and the chief scientific officer at Backfitpro Inc. (backfitpro.com/about-us) where he specializes in evaluating complex cases of lower back pain from across the globe.
In this clip, Peter and Stuart discuss:
- How to maximize the longevity of the spine - How young people should be thinking about keeping their spine healthy - The best exercises and resources for promoting back health - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useHow to properly incorporate isometric exercises into a workout | Peter Attia and Andy GalpinPeter Attia MD2024-02-16 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/3UFfA7k
This clip is from episode 239 ‒ The science of strength, muscle, and training for longevity with Andy Galpin, Ph.D. Andy Galpin is a professor of Kinesiology at California State University at Fullerton, where he studies muscle adaptation and applies his research to work with professional athletes.
In this clip, we discuss:
- Why is it that isometric training can elicit the same hypertrophy response as isotonic or movement-based contraction? - Does isometric offer any other advantage over safety? - Benefits of lifting with bands - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useIdentifying the cause of your lower back pain in order to resolve it | Peter Attia and Stuart McGillPeter Attia MD2024-02-15 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/4bsI9dY
This clip is from episode 287 - Lower back pain: causes, treatment, and prevention of lower back injuries and pain with Stuart McGill, Ph.D. Stuart McGill is a distinguished professor emeritus at the University of Waterloo and the chief scientific officer at Backfitpro Inc. (backfitpro.com/about-us) where he specializes in evaluating complex cases of lower back pain from across the globe.
In this clip, Peter and Stuart discuss:
- The psychological trauma that exists in patients with lower back pain - Why the medical system gives up on some patients with chronic back pain - Showing patients that they have the ability to mitigate pain through understanding the mechanical systems of the back - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useHow to gain muscle and strength if youre untrained and out of shape | Peter Attia and Andy GalpinPeter Attia MD2024-02-14 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/42EbHkX
This clip is from episode 239 ‒ The science of strength, muscle, and training for longevity with Andy Galpin, Ph.D. Andy Galpin is a professor of Kinesiology at California State University at Fullerton, where he studies muscle adaptation and applies his research to work with professional athletes.
In this clip, we discuss:
- Why it is important to spend time initially getting physically fit before trying to pack on muscle - Changes in muscle and muscular function that occur with aging - Advice for the first six months of getting into training - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-usePeters experience with debilitating back pain | Peter Attia & Stuart McGillPeter Attia MD2024-02-13 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/3Sz22HP
This clip is from episode 287 - Lower back pain: causes, treatment, and prevention of lower back injuries and pain with Stuart McGill, Ph.D. Stuart McGill is a distinguished professor emeritus at the University of Waterloo and the chief scientific officer at Backfitpro Inc. (backfitpro.com/about-us) where he specializes in evaluating complex cases of lower back pain from across the globe.
In this clip, Peter and Stuart discuss:
- Why the topic of biomechanics for a healthy back is of great interest to Peter - How Peter hurt his back and why the pain kept returning - Why MRI doesn't always tell the full story of back pain - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useCancer screening: pros and cons, screening options, interpreting results, & more (AMA 56 sneak peek)Peter Attia MD2024-02-12 | View show notes here: bit.ly/4bMnAtp Become a member to receive exclusive content: peterattiamd.com/subscribe Sign up to receive Peter's email newsletter: peterattiamd.com/newsletter
In this “Ask Me Anything” (AMA) episode, the conversation focuses on cancer screening, a topic often shrouded in confusion yet crucial to understand given that early identification of a cancer is an essential part of survival strategy. Peter examines the arguments both for and against cancer screening, including addressing why some trials may show no benefit to screening. He then delves into the various screening modalities available for different cancers, highlights the pros and cons associated with each, and explains how to interpret the results. Additionally, Peter provides guidance for navigating outside of the relatively narrow and confined screening guidelines for various types of screening tests.
In this sneak peek, we discuss: 00:00 - Intro 00:12 - Why understanding cancer screening is crucial 02:08 - The prevalence of cancer diagnosis and mortality rates 09:09 - Why cancer screening and early detection is such an important part of the strategy to survive a cancer diagnosis 11:18 - Data on how cancer screening impacts survivability of cancer 14:45 - Inconsistencies between cancer screening trials regarding benefits to survival rates
In the full episode, we also discuss: -What are some of the reasons why clinical trials don’t always improve cancer-specific mortality?; -What are the arguments against population-level cancer screening?; -Cancer screening outside the recommended guidelines: risks and benefits, interpreting results, and other considerations; -Understanding sensitivity and specificity when reviewing screening results; -Risks and complications associated with colonoscopies; -Cancer screening modalities: options for cancer screening both within standard recommendations and beyond; -The strengths and limitations of various types of cancer screening; -Understanding positive and negative predictive value using sensitivity, specificity, and pretest probability; -Factors that influence an individual's pretest probability of cancer; -How to interpret cancer screening results; -The importance of having an advocate when considering out-of-guideline cancer screening tests; -How stacking multiple cancer screening modalities can decrease the risk of false positives; -Advice and guidance for making decisions related to cancer screening; and -More.
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useHow increasing muscle mass can reduce joint pain | Peter Attia and Stuart McGillPeter Attia MD2024-02-11 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/493w910
This clip is from episode 287 - Lower back pain: causes, treatment, and prevention of lower back injuries and pain with Stuart McGill, Ph.D. Stuart McGill is a distinguished professor emeritus at the University of Waterloo and the chief scientific officer at Backfitpro Inc. (backfitpro.com/about-us) where he specializes in evaluating complex cases of lower back pain from across the globe.
In this clip, Peter and Stuart discuss:
- How stiffness in old age can lead to pain relief - Why increased muscle stiffness allows for pain reduction - Why having some arthritis can be a good thing - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useCreating a plan to finish strong at the end of life | Peter Attia and Walter GreenPeter Attia MD2024-02-10 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/3wcsLCg
This clip is from episode 288 - The impact of gratitude, serving others, embracing mortality, and living intentionally with Walter Green
In this clip, Peter and Walter discuss:
- When should people start thinking about finishing strong in life - The value of giving before you pass away - The importance of staying current with your relationships - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useFinding purpose in life through gratitude and serving others | Peter Attia and Walter GreenPeter Attia MD2024-02-09 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/480jc6Q
This clip is from episode 288 - The impact of gratitude, serving others, embracing mortality, and living intentionally with Walter Green
In this clip, Peter and Walter discuss:
- Why you should practice showing gratitude early in life - Why people who have a sense of purpose seem to live longer - The key to finding peace at the end of one's life - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useThe key to cultivating deep, authentic friendships | Peter Attia and Walter GreenPeter Attia MD2024-02-08 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/3HKpm0h
This clip is from episode 288 - The impact of gratitude, serving others, embracing mortality, and living intentionally with Walter Green
In this clip, Peter and Walter discuss:
- The importance of authenticity, empathy, and compassion - Building the skill of being a good friend - Why would someone want to be more authentic? - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useWhy mortality is a gift and what it can teach us | Peter Attia and Walter GreenPeter Attia MD2024-02-07 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/4btUC0U
This clip is from episode 288 - The impact of gratitude, serving others, embracing mortality, and living intentionally with Walter Green
In this clip, Peter and Walter discuss:
- How mortality can guide intentionality - Knowing when to say no - The concept of thinking in reverse - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useTell people what they mean to you before theyre gone | Peter Attia and Walter GreenPeter Attia MD2024-02-06 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/3SKMW3e
This clip is from episode 288 - The impact of gratitude, serving others, embracing mortality, and living intentionally with Walter Green
In this clip, Peter and Walter discuss:
- What started the “Say It Now” movement - How to get involved in the “Say It Now” movement - How to get younger people involved with “Say It Now” - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-use288 ‒ The impact of gratitude, serving others, embracing mortality, and living intentionallyPeter Attia MD2024-02-05 | View show notes here: bit.ly/3wckb6v Become a member to receive exclusive content: peterattiamd.com/subscribe Sign up to receive Peter's email newsletter: peterattiamd.com/newsletter
Walter Green is a remarkable philanthropist, mentor, author of This Is the Moment!, and founder of the impactful “Say It Now” movement. In this episode, Walter delves into the unique insights gained from his challenging upbringing, discusses embracing mortality, and highlights the mindset of “finishing strong.” He shares insights on intentionality, thinking in reverse, saying “no,” prioritizing relationships, and the essence of focusing on others. The conversation focuses on the “Say It Now” movement, which stresses the importance of expressing sentiments to loved ones well before the end of life.
We discuss: 0:00:00 - Intro 0:01:15 - How Peter and Walter met through Ric Elias 0:04:36 - The unique perspectives and life lessons provided by Walter’s challenging childhood 0:11:15 - Walter’s harrowing experience with a sudden mental breakdown and his subsequent recovery with the help of therapy 0:19:10 - A diverse professional journey ending in great success 0:24:00 - The birth of a movement: celebrating friendships through public tributes and expressing gratitude to those who have shaped your life’s journey 0:32:15 - Intentionality, thinking in reverse, saying “no”, and other guiding principles for Walter 0:42:45 - Walter’s global journey of gratitude on his 70th birthday: visiting friends and creating memorable experiences 0:50:40 - The profound impact of acknowledging and expressing gratitude for the people who contribute to our lives 0:57:32 - The key elements for creating meaningful connections and cultivating deep, authentic friendships 1:04:35 - The “Say It Now” movement: the inspiration behind the remarkably impactful initiative 1:24:43 - What “finishing strong” means to Walter 1:31:54 - Finding peace at the end of life through expressing gratitude and finding purpose in serving others 1:36:15 - Resources to learn about “Say It Now”
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-useDo the benefits of deadlifts and squats outweigh the risk of injury? | Peter Attia and Stuart McGillPeter Attia MD2024-02-04 | Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): bit.ly/3UggpmM
This clip is from episode 287 - Lower back pain: causes, treatment, and prevention of lower back injuries and pain with Stuart McGill, Ph.D. Stuart McGill is a distinguished professor emeritus at the University of Waterloo and the chief scientific officer at Backfitpro Inc. (backfitpro.com/about-us) where he specializes in evaluating complex cases of lower back pain from across the globe.
In this clip, Peter and Stuart discuss:
- The importance of correct movement patterns - Common injuries of people who deadlift - The idea of sufficient fitness - And more
-------- About:
The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 70 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: peterattiamd.com/terms-of-use