Is Free 25OH Vitamin D The Next Generation Vitamin D Marker? Labroots 2024-10-23 | Is Free 25OH Vitamin D The Next Generation Vitamin D Marker?
Tips, Tricks, and Optimization: A Users Guide to BOND RX and Chromogenic Multiplexing in Research.. Labroots 2022-11-19 | Presented By: Mark LawsonSpeaker Biography: Mark Lawson is an Applications Specialist on the Life Sciences team at Leica Biosystems, providing technical support for the Life Sciences portfolio including but not limited to the BOND RX, BOND RXm, and a wide array of reagents. Mark has worked in the field of histology for 15 years in both the clinical and research spaces, in roles ranging from histotechnologist to laboratory administrator.Webinar: Tips, Tricks, and Optimization: A User's Guide to BOND RX and Chromogenic Multiplexing in Research ApplicationsWebinar Abstract: Mark will help identify common problems researchers face when developing protocols in IHC and multiplex staining and share some helpful guidance, tips, and tricks for BOND RX users in solving these dilemmas. Topics will include developing best practices for setting up and running chromogenic multiplex slides, providing participants with step-by-step guides on configuring the BOND RX v7.0 software, and sharing insights on optimizing IHC and multiplex staining.Earn PACE Credits:1. Make sure you’re a registered member of Labroots ( labroots.com/ms/webinar/tips-tricks-optimization-user-s-guide-bond-rx-chromogenic-multiplexing-research-applications)2. Watch the webinar on YouTube or on the Labroots Website ( labroots.com/ms/webinar/tips-tricks-optimization-user-s-guide-bond-rx-chromogenic-multiplexing-research-applications)3. Click Here to get your PACE credits (Expiration date – 11/17/2024): (labroots.com/credit/pace-credits/7727/cert) Labroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
The evolution of carbon fixation: Studying Form I Rubisco using ancestral sequence reconstruction... Labroots 2022-11-19 | Presented By: Luca SchulzSpeaker Biography: I am a graduate student at the Max Planck Institute for Terrestrial Microbiology in Marburg, Germany under shared supervision by Georg Hochberg and Tobias Erb. My research focuses on understanding the evolution of protein complexes, particularly the carboxylase Rubisco that assimilates most inorganic carbon from the atmosphere.Webinar: The evolution of carbon fixation: Studying Form I Rubisco using ancestral sequence reconstruction and mass photometryWebinar Abstract: Up to now, the evolutionary trajectory of the most prevalent CO2-fixing enzyme – Rubisco Form I, has been difficult to study. The Rubisco found in today’s plants and algae has 8 small subunits (SSU) that are absent from its ancestral form. The SSU has become essential for the enzyme’s solubility and activity, hindering biochemical studies into its influence on Rubisco. Our research aimed to decipher how the obligate interaction between Rubisco and its SSU evolved. Earn PACE Credits:1. Make sure you’re a registered member of Labroots (labroots.com/ms/webinar/evolution-carbon-fixation-studying-form-rubisco-using-ancestral-sequence-reconstruction-mass-photome)2. Watch the webinar on YouTube or on the Labroots Website (labroots.com/ms/webinar/evolution-carbon-fixation-studying-form-rubisco-using-ancestral-sequence-reconstruction-mass-photome)3. Click Here to get your PACE credits (Expiration date – 11/17/2024): (labroots.com/credit/pace-credits/7723/cert) Labroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
Getting started in Cryo-EM: Virtual Workshop Labroots 2022-11-19 | Presented By: Natalia de Val / Zuben Brown / Veer BhattWebinar: Getting started in Cryo-EM: Virtual WorkshopWebinar Abstract: Cryo-electron microscopy (cryo-EM) has become the go-to method for life scientists around the world to view molecular details and protein structures in 3D, generating breakthroughs in the research of cancers, infectious and neurodegenerative diseases, and more. In this virtual workshop, join our experts for a demonstration of the EM workflow—from sample preparation to data collection—on the Thermo Scientific™ Tundra™ Cryo-TEM and see how easy and convenient is to get started with cryo-EM.Earn PACE Credits:1. Make sure you’re a registered member of Labroots (labroots.com/ms/webinar/getting-started-cryo-em-virtual-workshop)2. Watch the webinar on YouTube or on the Labroots Website (labroots.com/ms/webinar/getting-started-cryo-em-virtual-workshop)3. Click Here to get your PACE credits (Expiration date – 11/17/2024): (labroots.com/credit/pace-credits/7701/cert) Labroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
EM ICE - Workflows in Every Direction Labroots 2022-11-18 | Presented By: Seth VillarrealSpeaker Biography: Seth Villarreal is an Advanced Workflow Specialist in the nanotechnology products of Leica Microsystems, providing training and assistance with protocol refinement across a variety of room temperature and cryo-workflows. Seth performs extensive hands-on and virtual training in assisting the preparation of samples for research involving electron microscopy. He graduated from Case Western Reserve University, through single particle cryoTEM research in the areas of DNA repair and circadian rhythm, and then a subsequent fellowship at NINDS of the NIH to study vesicle fusion by TEM from primary cell culture.Webinar: EM ICE - Workflows in Every DirectionWebinar Abstract: High pressure freezing offers versatile and deep capability in the study of intricate changes in fine structure or cellular dynamics. From the internals of a single cell to complex layers within small whole organisms, the EM ICE occupies a key point in many electron microscopy (EM) workflows. These workflows extend from correlative light and electron microscopy (CLEM) methods to straightforward freeze substitution by resin embedding for ultramicrotomy. Labroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
Optimizing Immunopeptide Analysis Sample Preparation in Needle Biopsy Size Tissue Samples with AFA® Labroots 2022-11-18 | Presented By: Nicolas Autret, PhD & Marco Tognetti, PhDSpeaker Biography: Nicolas Autret earned a PhD in Microbiology from Université Paris 7 in 2003. He’s been holding several commercial roles in the past 16 years for different companies and his fields of expertise are biochemistry, molecular biology and cell culture. He works for Covaris since April 2018 as senior business development manager and he is responsible for the development of new applications in the field of protein analysis, using Covaris AFA technology. Recently, he set up collaborations with world leading mass spectrometry labs, including Jeroen Krijgsveld’s lab, to help establish high throughput sample preparation workflows for research and clinical proteomics.Dr. Tognetti is a principal scientist at Biognosys. He leads the R&D development of novel sample-processing solutions to enable deep, robust, and scalable proteome profiling. Most notably, he has recently contributed to deep plasma profiling and immunopeptide enrichment approaches and has developed optimized and automated workflows for large-scale proteomics. Dr. Tognetti obtained his B.Sc., M.Sc., and Ph.D. from ETH Zurich. Before joining Biognosys in 2020, his research at ETH Zurich and the University of Zurich brought him to integrate multiomics approaches to improve drug response prediction in breast cancer.Webinar: Optimizing Immunopeptide Analysis Sample Preparation in Needle Biopsy Size Tissue Samples with AFA®Webinar Abstract: Immunopeptides play an essential role in adaptive immunity by activating and ensuring T-cell specificity. Mass spectrometry (MS) is currently the only technology that can reliably measure and identify the immunopeptide profiles of biological samples at a large scale. However, quality of data in these assays is limited by sample input, extraction efficiency, and poor scalability. To address this issue, we optimized the native lysis of cells with AFA-based ultrasonication and immunoprecipitation while ensuring 96-well compatibility, scalability and reproducibility.Labroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
Verification of Autoantibody Serology Tests: Practical Considerations for the Clinical Laboratory Labroots 2022-11-18 | Presented By: Melissa R. Snyder, PhD, DABCCSpeaker Biography: Melissa R. Snyder, PhD completed her doctoral degree in Biochemistry through the Mayo Graduate School in 1997. She followed that with a post-doctoral fellowship in clinical/basic immunology, during which time she studied T-cell function in autoimmune disease, specifically rheumatoid arthritis. She then completed a clinical chemistry fellowship at the Mayo Clinic, where she focused on laboratory diagnostics and autoimmune disease. After completing her clinical fellowship, she was board-certified in Clinical Chemistry by the American Board of Clinical Chemistry.Webinar: Verification of Autoantibody Serology Tests: Practical Considerations for the Clinical LaboratoryWebinar Abstract: This webinar will examine how laboratories can fulfill regulatory requirements for verification of an autoantibody serology test, while acknowledging the unique challenges presented by these methods and heterogeneous analytes.Earn PACE Credits:1. Make sure you’re a registered member of Labroots (labroots.com/ms/webinar/verification-autoantibody-serology-tests-practical-considerations-clinical-laboratory)2. Watch the webinar on YouTube or on the Labroots Website (labroots.com/ms/webinar/verification-autoantibody-serology-tests-practical-considerations-clinical-laboratory)3. Click Here to get your PACE credits (Expiration date – 11/16/2024): (labroots.com/credit/pace-credits/7717/cert) Labroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
Enhance Your Cell and Gene Therapy Workflow with GenScript Tools Labroots 2022-11-17 | Presented By: Yuanyuan Shen & Yifan YuSpeaker Biography: Dr. Yuanyuan Shen got her Ph.D. degree from the University of Connecticut. She is now the Director for R&D team of Protein Product at GenScript, where she is directly responsible for the development of CRISPR gene editing related products.Yifan Yu received his PhD degree in the Department of Chemical Engineering at University of Florida, United States. During his PhD, his research work was focused on the modification of contact lenses to improve lubricity and using it as a novel drug delivery platform for the eye diseases. In his last stage of PhD, he joined Dr. Tanmay Lele’s lab, focusing on the quantitatively analysis of the cell nuclear migration and stalling forces and its impact for the cancer treatment.Webinar: Enhance Your Cell and Gene Therapy Workflow with GenScript Tools Webinar Abstract: In this webinar, the reagents, consumables and platform developed by GenScript will be shared for cell therapy workflow. The immunomagnetic technology for T cell and NK cell isolation will also be introduced by Dr. Yu. You will be able to learn how researchers scale up their operations and integrate with other instruments for all necessary cell processing steps easily.Labroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
Single cell antibody discovery using Islands of Automation Labroots 2022-11-17 | Presented By: Paul AndersonSpeaker Biography: Paul earned his bachelor’s degree in Chemical Engineering from the University of California, Santa Barbara then went on to Case Western Reserve University where he received a master’s in Biomedical Engineering in 2005. From 2005 to 2018 he worked in the Advanced Automation Technologies group at the Genomics Institute of the Novartis Research Foundation, better known as GNF. In the summer of 2018 he joined Eli Lilly in San Diego where he has helped build out automated platforms to support Lilly's Biologics Discovery efforts.Webinar: Single cell antibody discovery using 'Islands of Automation'Webinar Abstract: Eli Lilly, a global healthcare leader, has implemented a next generation research (NGR) initiative to improve the value output of the R&D portfolio. One of the NGR pillars focuses on decreasing the timeline to bring medicines to patients. Lilly has invested in ‘Islands of Automation’ to advance the B cell antibody discovery platform at the Lilly Biotechnology Center in San Diego with the goal of significantly increasing throughput and reducing project timelines.Labroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
Innovation in Science and Technology: Translating Cellular Therapies from Bench to Bedside Labroots 2022-11-17 | Presented By: Khalid Shah & Jean QiuSpeaker Biography: Dr. Khalid Shah is the Vice Chair of Research at Brigham and Women's Hospital (BWH) in Boston, MA. He is also the Director of the Center for Stem Cell and Translational Immunotherapy at BWH and a Principal Faculty at Harvard Stem Cell Institute in Boston.Dr. Jean Qiu started the company in 2003 from the basement of her home, intending to automate manual cell counting on the biologist’s lab bench. Today, the Cellometer-branded cell counting systems, including instrument, software, consumables, and reagents, are distributed globally and used in laboratories of pharmaceutical companies, government institutions, universities for cancer research, vaccine development, drug discovery, and cellular therapy manufacturing. Nexcelom Bioscience was acquired by PerkinElmer in June 2021.Webinar: Innovation in Science and Technology: Translating Cellular Therapies from Bench to BedsideWebinar Abstract: In this webinar, Dr. Khalid Shah, MS, Ph.D. Vice-Chair of Research Neurosurgery, from BWH, Harvard Medical School, will present strategies for effective development of cellular therapies via gene editing. He will also discuss how to develop and validate relevant tumor models to ensure the clinical translation of therapeutic cells.Earn PACE Credits:1. Make sure you’re a registered member of Labroots (labroots.com/ms/webinar/innovation-science-technology-translating-cellular-therapies-bench-bedside)2. Watch the webinar on YouTube or on the Labroots Website (labroots.com/ms/webinar/innovation-science-technology-translating-cellular-therapies-bench-bedside)3. Click Here to get your PACE credits (Expiration date – 11/16/2024): (labroots.com/credit/pace-credits/7668/cert) Labroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
Beyond SARS-CoV-2, application of Absolute Q digital PCR system for waterborne pathogens Labroots 2022-11-17 | Presented By: Huiyun WuSpeaker Biography: Dr. Huiyun Wu is a research scientist at Tulane University, School of Public Health and Tropical Medicine. Dr. Wu’s research activities are focused on waterborne pathogens in natural and built environment, the detection and surveillance, the fate and transport, and the metagenomic microbial community analysis.Webinar: Beyond SARS-CoV-2, application of Absolute Q digital PCR system for waterborne pathogensWebinar Abstract: Waterborne pathogens lead to deteriorating water quality and challenge global health and economy. The latest U.S. Environmental Protection Agency (EPA) Contaminant Candidate List (CCL4) contained 12 microbial contaminants, such as human adenoviruses, enteroviruses, noroviruses, Salmonella enterica, and Campylobacter jejuni, which are linked to enteric disease outbreaks. One of the challenges to detect enteric pathogens in environmental water samples is their low ambient concentrations, thus direct monitoring may not be possible. Labroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
Reverse engineering the human heart with pluripotent stem cells Labroots 2022-11-17 | Presented By: Aitor Aguirre, PhDSpeaker Biography: Dr. Aguirre is a stem cell biologist, developmental biologist and bioengineer working at Michigan State University. He completed his Ph.D. in stem cell applications for cardiovascular tissue engineering in 2010, and followed up as a postdoc in 2011 at the Salk Institute and the University of California San Diego to acquire training in cardiac development, regeneration, stem cell reprogramming, functional genomics and mass spectrometry-based metabolomics using both human induced pluripotent stem cells and animal models. Webinar: Reverse engineering the human heart with pluripotent stem cellsWebinar Abstract: Recent advances in stem cell technologies, synthetic development and organoid biology are enabling us to create more accurate in vitro models of human organs. Here we will discuss methods to generate developmentally relevant human heart organoids by self-organization strategies using human pluripotent stem cells. Our procedure is fully defined, efficient, reproducible, and compatible with high-content approaches. These organoids develop sophisticated internal chambers with well-organized multi-lineage cardiac cell types, recapitulate heart field formation, atrioventricular specification, develop a complex vasculature, anterio-posterior heart patterning, and exhibit robust functional activity. We also show that our organoid platform can recreate complex metabolic disorders associated with congenital heart defects.Labroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
Go with the flow for rapid viscosity results with Honeybun Labroots 2022-11-16 | Presented By: Kevin Lance, Ph.D.Speaker Biography: Kevin Lance is the Director of Biologics & Gene Therapy Marketing covering the global Analytical Instrument portfolio at Unchained Labs. His expertise covers biophysical characterization of proteins, nucleic acids, viral vectors, and LNPs. Prior to Unchained Labs, his research experience covered the fields of sustained antibody delivery and nanotechnology. He earned his Ph.D. in Bioengineering from the joint UC Berkeley – UCSF Bioengineering Graduate Program.Webinar: Go with the flow for rapid viscosity results with HoneybunWebinar Abstract: Learning Objectives-See how microfluidics make viscosity measurements simple and fast-Understand the impact concentration and formulation make on viscosity-Learn how viscosity can be an important part of your antibody and protein screening workflowLabroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
Antibody Discovery by Single B Cell Screening on Beacon® Labroots 2022-11-15 | Presented By: Amy Sheng, Ph.D.Speaker Biography: Dr. Amy Sheng is a technical account manager in Sino Biological. Dr. Sheng joined Sino Biological in 2021 supporting CRO services and project management in Eastern US region. Prior to joining Sino Biological, she worked in Caprico Biotechnologies as production manager in charge of antibody development and production for flow cytometry. She has a Ph.D. in Molecular and Cell Biology from Georgia Institute of Technology, and is ASCP-certified molecular biologist and ASQ-certified CSSGB.Webinar: Antibody Discovery by Single B Cell Screening on Beacon®Webinar Abstract: Single B cell screening is a powerful and efficient strategy for generating antigen-specific monoclonal antibodies. Distinguished with fluorescence-activated B cell sorting, the Beacon® platform is based on plasma cell screening, making it easier to obtain antibody genes.Earn PACE Credits:1. Make sure you’re a registered member of Labroots (labroots.com/ms/webinar/antibody-discovery-single-cell-screening-beacon)2. Watch the webinar on YouTube or on the Labroots Website (labroots.com/ms/webinar/antibody-discovery-single-cell-screening-beacon)3. Click Here to get your PACE credits (Expiration date – 11/10/2024): (labroots.com/credit/pace-credits/7704/cert) Labroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
Sample collection and concentration methods impact on wastewater-based surveillance for multi... Labroots 2022-11-15 | Presented By: Suporn PholwatSpeaker Biography: Suporn Pholwat grew up in a small village in northeastern Thailand. She left rural Thailand to seek a better education and received a PhD in Medical and Molecular Microbiology from Mahidol University in Thailand. After receiving the 2009 Pfizer Initiative in International Health Research Fellowship through Center for Global Health Equitiy at the University of Virginia, she moved to Charlottesville, VA to pursue a research career in infectious diseases. Webinar: Sample collection and concentration methods -- impact on wastewater-based surveillance for multi-pathogen panelsWebinar Abstract: Wastewater-based surveillance has gained wide recognition throughout the COVID-19 pandemic to monitor trends of SARS-CoV-2. While the current approaches focus on a single pathogen at a time, multi-pathogens surveillance is the future. Method to capture multi-pathogens in one go is not trivial. In our previous studies, we have found success recovering multi-pathogens from 6 liters of wastewater using the Bag Mediated Filtration System (BMFS) followed by skim milk flocculation. While this method performs well, it is costly and labor intensive. Therefore, we developed a new method using the Ceres Nanotrap® Microbiome A Particle, to capture pathogens from much smaller volumes of wastewater samples in Dhaka, Bangladesh. Earn PACE Credits:1. Make sure you’re a registered member of Labroots (labroots.com/ms/webinar/sample-collection-concentration-methods-impact-wastewater-based-surveillance-multi-pathogen-panels)2. Watch the webinar on YouTube or on the Labroots Website (labroots.com/ms/webinar/sample-collection-concentration-methods-impact-wastewater-based-surveillance-multi-pathogen-panels)3. Click Here to get your PACE credits (Expiration date – 11/10/2024): (labroots.com/credit/pace-credits/7642/cert) Labroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
The Basics of Protein AnalysisTopic 1: Fundamental of antibodies for applied research.... Labroots 2022-11-15 | Presented By: Dr. Audrey Lim & Dr. Anthony LimSpeaker Biography: A Product Manager (SEA) at Thermo Fisher Scientific since 2018, Audrey's mission is to advance science by empowering scientists with the latest innovations and technologies to propel their research forward. In her current role, Audrey’s expertise is in the fields of protein analysis, sample preparation and molecular biology.Anthony graduated from University of Melbourne with his BSc (Hons) degree before pursuing his PhD at the National University of Singapore, where he worked on Proteomics in Neuroscience. He has 6 years of post-doctoral experience in Cancer Research with A*STAR, before joining the industries where he took on several commercial roles, in drug discovery and commercial modalities. Anthony is currently the Technical Sales Leader for SEATW, focusing on enabling scientists with latest innovations and information.Webinar: The Basics of Protein AnalysisTopic 1: Fundamental of antibodies for applied researchTopic 2: Practical considerations for quantitation in western blottingWebinar Abstract: Antibodies are vital tools in many of the laboratory techniques that are used to answer basic research questions. Due to their high specificity and selectivity, antibodies have always had the potential to be of great use as biochemical tools for a range of applications including selection, identification, purification and as therapeutics. Being some of the most critical reagents used in the research lab, qualified validated antibodies will highly enhance research outcome by enabling superior performance for researchers. Along with ELISA, western blotting is still one of the most widely performed protein detection/immuno-detection applications.Earn PACE Credits:1. Make sure you’re a registered member of Labroots (labroots.com/ms/webinar/basics-protein-analysis-topic-1-fundamental-antibodies-applied-research-topic-2-practical-considerat)2. Watch the webinar on YouTube or on the Labroots Website (labroots.com/ms/webinar/basics-protein-analysis-topic-1-fundamental-antibodies-applied-research-topic-2-practical-considerat)3. Click Here to get your PACE credits (Expiration date – 11/07/2024): (labroots.com/credit/pace-credits/7557/cert) Labroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
How to improve patient management with molecular solutions for cervical cancer screening .... Labroots 2022-11-15 | Presented By: Anja Oštrbenk Valencak & Wieke KremerSpeaker Biography: Dr. Anja Oštrbenk Valencak is currently an Analyst in Laboratory Biomedicine at the Institute of Microbiology and Immunology and Faculty of Medicine at the University of Ljubljana, Slovenia. Throughout her career and extensive research in field of molecular diagnostics specifically in Human Papillomavirus (HPV), Anja has published over 30 peer reviewed articles. Known for her work in validating HPV molecular diagnostics tests in VALGENT framework to assess clinical performance, Anja has presented her research at international congresses such IPV and Eurogin. Wieke Kremer is a resident in obstetrics and gynaecology and currently working in OLVG, Amsterdam. From 2015-2019 she worked as a PhD candidate under supervision of prof. dr. Peter Snijders, prof. dr. Chris Meijer, prof. dr. Hans Berkhof and prof. dr. Gemma Kenter at the VU medical center, Amsterdam. Her research is focussed on the application of methylation markers in screening for cervical cancer and management of women with CIN.Webinar: How to improve patient management with molecular solutions for cervical cancer screening and CIN2/3 diagnosed womenWebinar Abstract: An increasing number of cervical cancer screening programs are converting from cytology to primary HPV-based organized screening because of better clinical performance. HPV assays need to be clinically validated and comply with international guidelines to assure high quality of primary HPV-based screening. Nevertheless screening also results in considerable overtreatment because many CIN2/3 lesions show spontaneous regression so a triage strategy is necessary and methylation can be used to support a wait-and-see policy in women with CIN2/3.Labroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
The Life of Her Mind Episode 3: Dr. Kisha Supernant Labroots 2022-11-15 | Dr. Kisha Supernant (Métis/Papaschase/British), Associate Professor at the University of Alberta, is a groundbreaking archaeologist revolutionizing the way we think about archaeology. She is an original contributor both to the body of knowledge about Indigenous communities and Indigenous feminism, and both mentors and supervises graduate students. Among her many professional commitments, Dr. Supernant is the Director of the Institute of Prairie & Indigenous Archaeology, and the Co-Director of the Situated Knowledges: Indigenous Peoples & Place Signature Area (SKIPP), and the Chair of Unmarked Graves Working Group of the Canadian Archaeological Association. Dr. Supernant research has led to numerous journal articles, book chapters, reports, and conference presentations. In addition, Dr. Supernant co-edited both ‘Archaeologies of the Heart’ (Springer, 2020) and ‘Blurring Timescapes, Subverting Erasure: Remembering Ghosts on the Margins of History’ (Berghahn Books, 2020). Dr. Supernant prioritizes “heart-centered archaeological practice,” which includes building collaborative research relationships between archaeology and indigenous communities. In furtherance of heart-centered practice, Dr. Supernant co-founded the H.E.A.R.T. collective in 2017 with fellow archaeologists, Natasha Lyons, Jane Baxter, and Sonya Atalay. By recognizing and integrating different knowledge systems into archaeological practice, a more robust and accurate understanding of the archaeological record can emerge.Archaeologies of the Heart - link.springer.com/book/10.1007/978-3-030-36350-5Blurring Timescapes, Subverting Erasure: Remembering Ghosts on the Margins of History - berghahnbooks.com/title/Surface-EvansBlurringAbout the series:The Life of Her Mind is dedicated to learning about how these women think — how they think about their careers, disciplines, and future. Each episode focuses on a single professional working in or around the sciences, with an eye toward uncovering what makes each individual’s contributions unique.The series is hosted by Labroots Science Writer Mia Wood, Ph.D., a philosophy professor and writer living and working at the intersection of philosophy and everything else. Among her relevant interests are the philosophy of early modern science, the nature of consciousness, and personal identity.
Addressing common challenges in lentiviral vector clarification using closed, automated counter.... Labroots 2022-11-10 | Presented By: Carl Dargitz & Magda TomalaSpeaker Biography: Carl Dargitz is a Manager in the Cell & Gene Therapy Platforms R&D group developing cell therapy instrumentation at Thermo Fisher Scientific. Previously, he developed reprogramming and characterization assays for PSCs and immune cells at Thermo Fisher. Before joining Thermo Fisher, he worked at the Salk Institute for Biological Studies at the stem cell core facility managing the core’s reprogramming and characterization services. He received his M.S. from California Polytechnic State University, San Luis Obispo in Biomedical Engineering with a specialization in stem cell research in 2013Magda Tomala, Manager of Testing Solutions and Analytics at Sartorius, is providing technological and process leadership in the field of viral and non-viral based applications. Before joining Sartorius, Magda worked for Crucell (now Janssen Vaccines) and Novartis, where she held various scientific and managerial roles in the process development areas for Cell Based Vaccines, Biologics and Cell and Gene Therapies. Amongst her involvement in process intensification and technology transfer, she contributed to the successful submissions of several viral vector INDs and the BLA for the CAR-T cell therapy Kymriah, which obtained FDA approval in 2017. Magda holds a PhD degree in Biotechnology / Technical Chemistry from Leibniz University of Hannover (Germany).Webinar: Addressing common challenges in lentiviral vector clarification using closed, automated counterflow centrifugation systemsWebinar Abstract: The field of cell and gene therapy is rapidly growing. In particular, the use of lentiviruses in CAR-T applications is becoming of higher importance. Lentiviruses are enveloped viruses that are rather large (100-150nm) and are therefore very fragile due to the membrane surrounding the capsid produced when lentiviruses are budding from cells. Large enveloped viruses pose serious challenges during the downstream operation, leading to poor recovery and low infectivity and thus high manufacturing costs. One key challenge in the downstream process of lentivirus production is the clarification step where you need to separate this large virus from the cells that produced it.Earn PACE Credits:1. Make sure you’re a registered member of Labroots (labroots.com/ms/webinar/addressing-common-challenges-lentiviral-vector-clarification-using-closed-automated-counterflow-cent)2. Watch the webinar on YouTube or on the Labroots Website (labroots.com/ms/webinar/addressing-common-challenges-lentiviral-vector-clarification-using-closed-automated-counterflow-cent)3. Click Here to get your PACE credits (Expiration date – 11/09/2024): (labroots.com/credit/pace-credits/7643/cert) Labroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
Clinical and Operational Aspects of Measuring Hemoglobin A1c by Capillary Electrophoresis Labroots 2022-11-10 | Presented By: David G. Grenache, PhD, D(ABCC)Speaker Biography: Dr. Grenache is the chief scientific officer for TriCore Reference Laboratories in Albuquerque, New Mexico. In that role, he leads the TriCore Research Institute and works cooperatively to develop and implement TriCore's scientific research strategy.Webinar: Clinical and Operational Aspects of Measuring Hemoglobin A1c by Capillary ElectrophoresisWebinar Abstract: Hemoglobin A1c is used clinically as a biomarker for the diagnosis and management of diabetes mellitus. Various methods are available to measure HbA1c and each has advantages and limitations. The focus of this presentation is on the clinical and operational aspects of using capillary electrophoresis as an analytical method for HbA1c measurement.Labroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
Fundamentals of Hematoxylin and Eosin Staining Labroots 2022-11-10 | Presented By: Cindy SampiasSpeaker Biography: Cindy Sampias is a board certified Cyto- and Histo-technologist and one of the original Core Histology Applications Specialists at Leica Biosystems. She is currently an Applications Technical Team Lead at Leica Biosystems. With more than 25 years of experience, she is a guest speaker at histology and cytology meetings around the country. She is a technical author for Media Lab, publishing a variety of technical courses and sharing best practices in histology.Webinar: Fundamentals of Hematoxylin and Eosin StainingWebinar Abstract: For characterizing tissue, the use of H&E is by far preferred for viewing cellular and tissue structure detail. The variation of stain intensity is often driven by the slide reviewers' learning experience and what they are comfortable seeing. Because this stain demonstrates a broad range of cytoplasmic, nuclear, and extracellular matrix features, nearly all teaching texts use H&E images. We continue to use this simple and essential stain today, which has remained unchanged for over a century.Earn PACE Credits: 1. Make sure you’re a registered member of Labroots ( labroots.com/ms/webinar/fundamentals-hematoxylin-eosin-staining)2. Watch the webinar on YouTube or on the Labroots Website ( labroots.com/ms/webinar/fundamentals-hematoxylin-eosin-staining)3. Click Here to get your PACE credits (Expiration date – 11/08/2022): (labroots.com/credit/pace-credits/7602/cert) Labroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
Thinking translational: Things to consider in CAR T cell workflows Labroots 2022-11-10 | Presented By: Robert DaviesSpeaker Biography: Robert earned a B.S. in Molecular, Cell and Developmental Biology at the University of California Santa Cruz and a Master of Bioscience (M.B.S) degree at the Keck Graduate Institute of Applied Life Sciences. After spending time as an academic researcher and marketing professional in various life science companies, Robert now manages the cell culture portfolio at Miltenyi Biotec Inc. As a product manager, Robert is dedicated to supporting industry leaders with the discovery, development and commercialization of various therapies, including cell and gene therapies.Webinar: Thinking translational: Things to consider in CAR T cell workflowsWebinar Abstract: Developing safe and effective CAR T cell therapies is a challenging task. That’s why thinking translational early in research experiments is important. Suitable tools will later enable a smooth transition from small-scale to large-scale workflows. Join us as we discuss how to set up your small-scale research workflow to ease up the transition to large-scale manufacturing in preclinical development. There will be time for questions and discussion after the 30-minute presentation.Earn PACE Credits:1. Make sure you’re a registered member of Labroots (labroots.com/ms/webinar/thinking-translational-consider-car-cell-workflows-2)2. Watch the webinar on YouTube or on the Labroots Website (labroots.com/ms/webinar/thinking-translational-consider-car-cell-workflows-2)3. Click Here to get your PACE credits (Expiration date –11/08/2024): (labroots.com/credit/pace-credits/7724/cert) Labroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
22x Assays Revolutionized and Still Turning! - DURAClone Dry Reagents for Flow Cytometry Labroots 2022-11-10 | Presented By: Michael Kapinsky, PhDSpeaker Biography: Michael Kapinsky has a strategic marketing role at Beckman Coulter's Flow Cytometry division. As a member of the global business unit, Michael owns responsibility for the clinical research product line branded as DURAClone and contributes to Beckman Coulter's strategic clinical research initiative. Michael joined Beckman Coulter in 2002. Webinar: 22x Assays Revolutionized and Still Turning! - DURAClone Dry Reagents for Flow CytometryWebinar Abstract: While flow cytometry shines by its flexibility, it requires a high level of expertise in antibody panel development, relies on experienced operators and is often challenged by inconsistent and unstable reagent quality. DURAClone dry antibody panels and stimulation mixes are a game-changer in conducting flow cytometry as they eliminate the burden of panel design, reduce reagent aging and at the same time remove antibody pipetting and stimulant handling from the resulting streamlined workflow.Labroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labroots Instagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
Power up your LNP & AAV sample prep with Unagi Labroots 2022-11-10 | Presented By: Del Ray JacksonSpeaker Biography: Del Ray Jackson, PhD has been working as a product manager for nearly a decade, helping several biopharma groups accelerate their drug discovery and development processes with lab automation. Since coming to Unchained Labs, he’s been able to focus on delivering automated, high throughput solutions for buffer exchange in biologics and gene therapy research and development.Webinar: Power up your LNP & AAV sample prep with UnagiWebinar Abstract: Learning Objectives-1) Outline how buffer exchange used across biologics & gene therapy2) Discuss limitations of manual buffer exchange for LNPs and AAVs3) Discover benefits of automated buffer exchange in improved results Labroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labroots SnapChat: labroots_inc
Targeting The Glyco-immune Checkpoints, Siglecs, to Enhance Anti-Viral Innate Immune Functions Labroots 2022-11-04 | Presented By: Mohamed Abdel-MohsenSpeaker Biography: My research focuses on understanding the role of the host glycosylation machinery in viral persistence and immunopathogenesis. Over the last decade, I have significantly contributed to over 70 peer-reviewed studies.Webinar: Targeting The Glyco-immune Checkpoints, Siglecs, to Enhance Anti-Viral Innate Immune FunctionsWebinar Abstract: Most known immune checkpoints exert their effects upon protein-protein interactions, such as the PD1 checkpoint on CD8+ T cells suppresses their functions upon binding to the PDL-1 molecule on target cells. However, recently, it became clear that another emerging class of immune checkpoints exert their effects upon protein-glycan (sugar) interactions, and therefore they are called glyco-immune checkpoints. Every immune cell expresses several sugar-binding proteins called lectins on its surface, and the binding between these lectins and their glycan ligands (on target cells) plays an essential role in the ability of these immune cells to recognize and lyse their target cells.Labroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
Prepare your lab for Flu Season with Multiplex PCR Labroots 2022-11-04 | Presented By: Peter Friebe, Ph.D. & Lauren MillerSpeaker Biography: Dr. Peter Friebe (Ph.D.) is a Senior Manager for Clinical Application and Marketing Support at Thermo Fisher Scientific. He has decades of research experience and brings extensive knowledge and experience in the fields of molecular diagnostic application development and support. Lauren Miller is a Scientist in the Clinical Application and Marketing Support team at Thermo Fisher Scientific, with a background in regulatory, molecular biology, and biotechnology. Prior to joining Clinical Application and Marketing Support, Lauren worked as a medical device auditor at a Notified Body, authorized as Lead Auditor for ISO 13485:2016, MDSAP, and IVDD.Webinar: Prepare your lab for Flu Season with Multiplex PCRWebinar Abstract: In this webinar, our speakers will provide an introduction into the epidemiology of influenza A/B, RSV, COVID-19, Adenovirus, Human Metapneumovirus, Rhinovirus, Enterovirus, and Parainfluenza, explaining why it is important to test and differentiate all these respiratory viruses using broader multiplex PCR testing.Earn PACE Credits:1. Make sure you’re a registered member of Labroots (labroots.com/ms/webinar/prepare-lab-flu-season-multiplex-pcr)2. Watch the webinar on YouTube or on the Labroots Website (labroots.com/ms/webinar/prepare-lab-flu-season-multiplex-pcr)3. Click Here to get your PACE credits (Expiration date – 11/3/2024): (labroots.com/credit/pace-credits/7658/cert) Labroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
X9 Real-Time PCR System: An Innovative High-Capacity Genomics System for Superior Efficiency Labroots 2022-11-04 | Presented By: Luca Boveri, PhD & Michael Gonzales, PhDSpeaker Biography: Luca Boveri joined Standard BioTools in 2020 as Director of Global Product Management and is now responsible for the Microfluidic Instruments portfolio. He earned an MSc and a PhD in Molecular Biology and Genetics from the University of Pavia in Italy.Michael Gonzales has served in various roles at Standard BioTools since 2013 and is now Director of Systems Integration for microfluidics systems. He received his PhD from in Molecular and Cellular Pharmacology from the University of Wisconsin-MadisonWebinar: X9 Real-Time PCR System: An Innovative High-Capacity Genomics System for Superior EfficiencyWebinar Abstract: Join the webinar to learn how the X9 Real-Time PCR System can empower your laboratory to obtain deeper insights from a large number of samples in a single experiment and help you better profile your biological system while saving time and resources.Labroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
Vertical rotors and how to achieve higher purity and yield viral vectors with greater efficiency Labroots 2022-11-02 | Presented By: Shawn Sternisha PhDSpeaker Biography: Shawn Sternisha is currently a Senior Field Applications Scientist in the Biotechnology Business Unit at Beckman Coulter Life Sciences where he develops applications and supports all centrifuge product lines. Shawn attended Illinois State University for his undergraduate studies and went on to earn his Ph.D. in Biochemistry at Florida State University. Webinar: Vertical rotors and how to achieve higher purity and yield viral vectors with greater efficiencyWebinar Abstract: Density gradient ultracentrifugation is known to provide high purity and high yield viral vector separations required for gene therapy therapeutics. By using a vertical rotor purpose-built for density gradient separations, users can separate empty and full viral capsids faster and with better resolution. Furthermore, with the launch of Beckman Coulter’s VTi 50.1 rotor, the advantages that inherently come with vertical rotors are coupled with 50% more throughput than the Type 70 Ti rotor.Labroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
Unveil the inflammatory response with novel assays for protein and gene expression Labroots 2022-11-02 | Presented By: Sigrun Badrnya, PhDSpeaker Biography: Sigrun Badrnya is a Manager in Product Development at the Thermo Fisher Scientific Center of Excellence for Immunoassays in Vienna, Austria. Sigrun received her PhD in vascular biology from the Medical University of Vienna in Austria. She continued as postdoctoral researcher at the Karolinska Institute in Stockholm, Sweden and within an industry-academia joint project, where she focused on the development of multiplex protein biomarker assays. In her current role she is supervising an R&D team to develop immunoassays across diverse platforms including InvitrogenTM ELISA, ProcartaPlexTM and ProQuantumTM technologies.Webinar: Unveil the inflammatory response with novel assays for protein and gene expressionWebinar Abstract: As part of the immune response, inflammation plays a vital role in the host defense and is dictated by the balance between stimulatory and inhibitory mediators. Inappropriate regulation of inflammation is an underlying contributor to many common pathological conditions. RNA and protein biomarkers can be effective indicators of (patho-)physiological processes and therefore their accurate quantitation critical to better understand the causative mechanisms of various (inflammatory) disorders.Earn PACE Credits:1. Make sure you’re a registered member of Labroots (labroots.com/ms/webinar/unveil-inflammatory-response-novel-assays-protein-gene-expression)2. Watch the webinar on YouTube or on the Labroots Website (labroots.com/ms/webinar/unveil-inflammatory-response-novel-assays-protein-gene-expression)3. Click Here to get your PACE credits (Expiration date –11/02/2024): (labroots.com/credit/pace-credits/7669/cert) Labroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
Debunking Antibody Titration Myths Labroots 2022-11-02 | Presented By: Diana BonillaSpeaker Biography: Diana studied Microbiology and Clinical Laboratory in Colombia. She is also an Immunologist, with a Ph.D. from Texas A&M University, a postdoctoral degree from Baylor College of Medicine and an ASCP-accreditation as a cytometry specialist. She has more than 20 years of experience as a biomedical scientist for a variety of applications, including infectious diseases and cancer, working as a senior scientist at MD Anderson Cancer Center.Webinar: Debunking Antibody Titration MythsWebinar Abstract: In this webinar, we will cover the fundamentals of antibody titrations, a critical step in the development and optimization of multicolor flow cytometry assays. We will discuss best practices and the validity of commonly held beliefs around antibody titrations. Labroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
Eavesdropping on Biological Processes with Multimodal and Multiplex Imaging Labroots 2022-11-02 | Presented By: Scott Fraser, PhDSpeaker Biography: Professor Scott E. Fraser has a long-standing commitment to quantitative biology, applying the tools of chemistry, engineering, and physics to problems in biology and medicine. His personal research centers on imaging and molecular analyses of intact biological systems, with an emphasis on early development, organogenesis, and medical diagnostics. After training in physics (B.S., Harvey Mudd College, 1976) and biophysics (Ph.D., Johns Hopkins University, 1979), he joined the faculty at UC Irvine, and rose through the ranks to become Chair of the Department of Physiology and Biophysics. In 1990 he moved to Caltech to serve as the Anna L. Rosen Professor of Biology, and the Director of the Biological Imaging Center.Webinar: Eavesdropping on Biological Processes with Multimodal and Multiplex ImagingWebinar Abstract: Molecular imaging of living specimens offers a means to draw upon the growing body of high-throughput molecular data to better understand the underlying cellular and molecular mechanisms of complex events ranging from embryonic development to disease processes. However, imaging approaches are challenged by unavoidable tradeoffs between spatial resolution, temporal resolution, field of view and the limited photon budget.Earn PACE Credits:1. Make sure you’re a registered member of Labroots (labroots.com/ms/webinar/eavesdropping-biological-processes-multimodal-multiplex-imaging)2. Watch the webinar on YouTube or on the Labroots Website (labroots.com/ms/webinar/eavesdropping-biological-processes-multimodal-multiplex-imaging)3. Click Here to get your PACE credits (Expiration date – 11/01/2024): (labroots.com/credit/pace-credits/7734/cert) Labroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
Flow cytometric gene mutation assay, made possible by immunomagnetic separation, achieves OECD.... Labroots 2022-11-02 | Presented By: Joe Ostrand, Ph.D. & Jeffrey Bemis, Ph.D.Speaker Biography: Joe Ostrand received his PhD in molecular biology from UCSD in 2018 and has been a member of Miltenyi’s cytometry team ever since. He has worked on a wide variety of flow cytometry applications, from algal strain development to clinical manufacturing release assays and multi-plate cytometry automation systems.Dr. Jeffrey Bemis received his PhD in Environmental Health and Toxicology from the University at Albany School of Public Health in Albany, NY. His thesis focused on the effects of combined exposure to the environmental contaminants polychlorinated biphenyls (PCBs) and methyl mercury on central neurotransmitter systems.Webinar: Flow cytometric gene mutation assay, made possible by immunomagnetic separation, achieves OECD regulatory statusWebinar Abstract: Litron laboratories developed the Pig-a gene mutation assay as a means to simply and reliably evaluate the potential mutagenicity of compounds. Commercially available from Litron Laboratories under the name MutaFlow, this method utilizes the endogenous phosphatidylinositol glycan class A gene found in most mammalian species as a reporter of gene mutation. During early development, the assay was challenged by the rare event nature of this analysis and the time and effort required to interrogate a sufficient number of events in order to reliably calculate a mutation frequency in peripheral red blood cells. Following the addition of labeling of cells with superparamagnetic beads and the use of immunomagnetic columns to focus analysis on the cells of interest, the sample throughput and number of events scored was dramatically increased.Labroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
Performance comparison of Bruker MBT Sepsityper® Kit US IVD for culture-independent identification.. Labroots 2022-11-02 | Presented By: Lindsey Singer, MSSpeaker Biography: My name is Lindsey Singer, and I am a Clinical Laboratory Technologist at Westchester Medical Center. I am a Master of Science Candidate for Clinical Laboratory Sciences at New York Medical College with expected graduation in May of 2022. My prior education includes a Bachelor of Science in biology from the State University of New York at Geneseo, in which I graduated from in 2020. Webinar: Performance comparison of Bruker MBT Sepsityper® Kit US IVD for culture-independent identification and antimicrobial susceptibility testing from positive blood culturesWebinar Abstract: Rapid and efficient organism identification and antimicrobial susceptibility reports are paramount for patient survival during sepsis. The Bruker MBT Sepsityper® Kit US IVD allows harvesting of microorganism directly from positive blood cultures and pairs it with the Bruker MALDI Biotyper® CA System for rapid identification of bacterial isolates using MALDI-TOF technology. Here we compare the accuracy of the MBT Sepsityper® Kit US IVD for bacterial identification to culture-based methods. Further, as an off-label use of the kit, we compare the antimicrobial susceptibility results for Gram-negative bacteria setup directly using the harvested pellet to the established method in the laboratory. To conclude the webinar, there will be an interactive Q & A session.Earn PACE Credits:1. Make sure you’re a registered member of Labroots (labroots.com/ms/webinar/performance-comparison-bruker-sepsityper-kit-ivd-culture-independent-identification-antimicrobial-su)2. Watch the webinar on YouTube or on the Labroots Website (labroots.com/ms/webinar/performance-comparison-bruker-sepsityper-kit-ivd-culture-independent-identification-antimicrobial-su)3. Click Here to get your PACE credits (Expiration date – 11/01/2024): (labroots.com/credit/pace-credits/7580/cert) Labroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
Stirred tank bioreactors in vaccine development - Producing AAV particles and COVID-19.... Labroots 2022-10-31 | Presented By: Jorge EscobarSpeaker Biography: Jorge Escobar is a senior research scientist in the applications lab of Eppendorf, Inc., in Enfield, Connecticut, USA. He joined the company in 2019 and has worked on applied research focused on efficient expansion of adherent and non-adherent cells (e.g. stem cells, adult primary cells) in cell culture bioreactors.Webinar: Stirred tank bioreactors in vaccine development - Producing AAV particles and COVID-19 spike-proteins in suspension cultureWebinar Abstract: Vaccines are essential tools for resisting pathogens and controlling global pandemics. Various types of virus vaccines, such as live attenuated, inactivated pathogen and subunit vaccines have been widely produced using mammalian cell cultures. However, they often rely on attachment cell culture. For higher production capacity, increased yield, and most importantly, ease of production scale-up, it is more desirable to produce vaccines in suspension cell culture platforms.Labroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
Comprehensive characterization of protein therapeutics using electron activated dissociation (EAD) Labroots 2022-10-31 | Presented By: Haichuan LiuSpeaker Biography: Haichuan Liu is currently a Sr. Biopharma Applications Scientist at SCIEX, specializing in LC-MS characterization of protein therapeutics. Haichuan has gained extensive experience in analysis of a wide range of biomolecules using mass spectrometry techniques throughout his career. Haichuan obtained his Ph.D. in gas phase chemistry in 2004 from the Hong Kong University of Science and Technology.Webinar: Comprehensive characterization of protein therapeutics using electron activated dissociation (EAD)Webinar Abstract: Electron activated dissociation (EAD) offered by the ZenoTOF 7600 system is a powerful tool for comprehensive characterization of protein therapeutics. Compared to traditional low-energy ExD approaches, the Zeno trap-boosted EAD offers a faster scanning rate and higher sensitivity, making it amenable as a single injection platform method for routine biopharma characterization. Additionally, the ability to tune electron kinetic energy in EAD enables its application to challenging molecules such as singly charged species and sulfated peptides.Labroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
PFAS 101: what are they, where are they, how do we test for them? Labroots 2022-10-31 | Presented By: Karl Oetjen, PhDSpeaker Biography: Karl Oetjen is a Senior Scientist at SCIEX in the technical marketing group and has over 10 years of mass spectrometry experience. Before joining SCIEX, he completed his PhD at Colorado School of Mines (Golden, Colorado) in Hydrologic Science and Engineering under Dr. Chris Higgins. Karl’s dissertation research focused on nontarget characterization of complex surfactant mixtures, including aqueous film forming foams. Webinar: PFAS 101: what are they, where are they, how do we test for them?Webinar Abstract: Per- and polyfluoroalkyl substances (PFAS) are manmade chemicals used in multiple industries - from paint to food packing - due to their surfactant and non-stick properties. In recent years PFAS have seen increasing attention from regulators as our understanding of their environmental persistence and biological impacts have evolved. Labroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
The health economic value of laboratory information in hepatitis C screening programs Labroots 2022-10-31 | Presented By: Dr. Paul Jülicher, PhDSpeaker Biography: Paul Juelicher is Senior Director Medical Affairs, Health Economics & Outcomes Research (HEOR) at Abbott Diagnostics. He graduated in chemistry, and he holds a PhD in natural science and biosensorics from the University of Muenster, Germany. He has a multifunctional record with more than 20 years in health care with experiences in R&D, as Lab Manager, as Head of Production, and in several commercial positions within the medical devices and diagnostics industry.Webinar: The health economic value of laboratory information in hepatitis C screening programsWebinar Abstract: In the global fight toward Hepatitis C elimination, hear insights into how to build a cost-effective screening program that is evidence based and improves outcomes by leveraging immunoassay-based testing algorithms. Hear how one country leveraged an anti-HCV and HCV Ag testing algorithm in their HCV screening program to increase the number of patients who ultimately received a complete diagnosis while also reducing the overall program cost. Labroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
Endotoxin Testing Platforms: How traditional techniques compare to recent industry developments..... Labroots 2022-10-31 | Presented By: Meg ProvenzanoSpeaker Biography: Meg Provenzano is the Product Manager for Sievers Bio-detection Instruments at SUEZ – Water Technologies & Solutions. She has over 10 years of experience in the bacterial endotoxin testing industry and has held several positions in Quality Control, Technical Support, and Product Management. She is customer-centric and enjoys problem-solving hands-on, whether for technical issues, assay assistance, or software. Meg holds a B.S. in Marine Science and Biology from Coastal Carolina University where she focused on Bottlenose Dolphin population research.Webinar: Endotoxin Testing Platforms: How traditional techniques compare to recent industry developments and how ease of use, productivity, and data integrity can be improvedWebinar Abstract: In this webinar, attendees will be provided an overview of the technologies that currently exist for bacterial endotoxins testing (BET), and the drawbacks associated with each. Microfluidic technology will be discussed with the intent of educating the audience on the advantages it has over the traditional gel clot/96 well plate methods and how through implementing microfluidic technology, quality control lab testing can be leaned out with respect to LAL testing and sustainability.Labroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
Spatially defining the future of cancer biology with advanced multiplexed immunofluorescence Labroots 2022-10-31 | Presented By: Troy BloomSpeaker Biography: Troy is an experienced analytical histotechnologist with expertise in histology, immunohistochemistry, in situ hybridization, digital slide scanning and image analysis within the GLP/GCP and pre-clinical environments along with a strong multidisciplinary CDx and research experience in models of oncology and autoimmune diseases.Webinar: Spatially defining the future of cancer biology with advanced multiplexed immunofluorescenceWebinar Abstract: Immunotherapy has transformed the treatment of metastatic and recurrent solid tumors. Advances in technology in the past few years have created unprecedented opportunities to identify biomarkers of disease processes, especially by using multi-omics technologies and datasets to derive valid and useful signatures of disease.Labroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
PCR Testing Reveals the SUC is Not So Golden of a Standard of Care Labroots 2022-10-31 | Presented By: Becky Winslow, BS, PharmD & Mayil Shanmugam, PhDSpeaker Biography: Dr. Becky Winslow graduated magna cum laude with her Bachelor of Science in Biology and her Doctor of Clinical Pharmacy degrees from Campbell University. Before founding inGENEious RX, LLC. (IGRX), Precision Medicine Consultants, Dr. Winslow directed pharmacy business operations and clinical pharmacy programs; and provided direct patient care for Walmart Stores, Community Health Systems, Neil Medical Group, and the North Carolina Department of Health and Human Services.Dr. Shanmugam, Senior Scientist and Director of Molecular and Microbiology, has extensively researched topics such as the pathogenic trait identification of bacteria and its genetic modifications, DNA and RNA sequence analysis, new peptide therapeutic molecules for possible cancer therapeutics and transposon mutagenesis for microbial gene characterization using next generation sequencing. He was conferred a Co-Principal Investigator – NIH Exploratory/Developmental Research Grant Award (R21) 2018-2020 and was a recipient of a Howard Hughes Medical Institute ( HHMI) fellowship.Webinar: PCR Testing Reveals the SUC is Not So Golden of a Standard of CareWebinar Abstract: In this webinar, Dr. Becky Winslow, infectious disease clinical scientist, details urinary tract infections’ incidence and impacts; the standard urine culture’s (SUC) technical challenges identifying slow-growing, fastidious, nonaerobic, and most gram-positive microorganisms; polymerase chain reaction’s (PCR) technical advantages identifying the same challenging to grow microorganisms; and the differences between the patient’s urinary tract infection diagnosis and treatment journey when a prescriber uses the standard urine culture as compared to the prescriber using polymerase chain reaction testing to identify and treat the patient. Earn PACE Credits:1. Make sure you’re a registered member of Labroots (labroots.com/ms/webinar/pcr-testing-reveals-suc-golden-standard-care)2. Watch the webinar on YouTube or on the Labroots Website (labroots.com/ms/webinar/pcr-testing-reveals-suc-golden-standard-care)3. Click Here to get your PACE credits (Expiration date –10/26/2024): (labroots.com/credit/pace-credits/7681/cert) Labroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
COVID-19: looking ahead to winter 2022-23 and beyond Labroots 2022-10-31 | Presented By: Giuliana Lo CascioSpeaker Biography: Giuliana Lo Cascio is a Clinical Microbiologist and Chief of the Microbiology Laboratory, Department of Clinical Pathology of the Azienda USL of Piacenza, Italy. She is also a lecturer in the Postgraduate School of Microbiology and Virology at the University of Pavia, Italy. Dr Lo Cascio main field of scientific research is mycology, with a particular focus on new diagnostic methods for rapid diagnosis of invasive fungal infections and on fungal susceptibility tests. Webinar: COVID-19: looking ahead to winter 2022-23 and beyondWebinar Abstract: The aim of this webinar is to discuss best practice organization methods in preparation for the third winter season of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. Early and accurate diagnosis is crucial to supporting medical decisions and preventing the diffusion of SARS-CoV-2. To control and monitor its epidemiology, the detection of SARS-CoV-2 specific RNA by rRT-PCR is currently considered the gold standard. Earn PACE Credits:1. Make sure you’re a registered member of Labroots (labroots.com/ms/webinar/covid-19-looking-ahead-winter-2022-23-beyond)2. Watch the webinar on YouTube or on the Labroots Website (labroots.com/ms/webinar/covid-19-looking-ahead-winter-2022-23-beyond)3. Click Here to get your PACE credits (Expiration date – 10/26/2024): (labroots.com/credit/pace-credits/7662/cert) Labroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
Applications of IR Biotyper®: Biosurveillance of Candida auris and 2 Tales of Salmonella spp Labroots 2022-10-31 | Presented By: Dr. Deisy ContrerasSpeaker Biography: Dr. Deisy Contreras is the Clinical Associate at Cedars-Sinai Medical Center. Deisy received her Ph.D. in Biomedical Science and Translational Medicine from Cedars-Sinai Medical Center. She then moved on to complete her CPEP Clinical Fellowship at UCLA and became board certified by the American Board of Medical Microbiology (ABMM) in 2019. She joined the clinical team at Cedars in 2020 where she has been in integral part of implementing numerous molecular diagnostic assays for clinical virology and the Special Pathogens Team. She has a passion for seeking out new technology applications as it pertains to diagnostics in infectious disease.Webinar: Applications of IR Biotyper®: Biosurveillance of Candida auris and 2 Tales of Salmonella sppWebinar Abstract: Candida auris is a multi-drug resistant yeast that continues to be a global threat for infection and transmission in hospitals, skilled nursing, and long-term care facilities. Cases of C. auris continue to rise and have increased by 318% since the first case reported in the US back in 2015. Here, we discuss implementation of an effective diagnostic surveillance algorithm needed for the prevention of nosocomial spread of C. auris within the hospital setting, which includes the rapid identification of C. auris by RT-PCR assay coupled with the Bruker IR Biotyper® for C. auris strain typing to provide tracing information for outbreak investigation. Earn PACE Credits:1. Make sure you’re a registered member of Labroots (labroots.com/ms/webinar/applications-ir-biotyper-biosurveillance-candida-auris-2-tales-salmonella-spp)2. Watch the webinar on YouTube or on the Labroots Website (labroots.com/ms/webinar/applications-ir-biotyper-biosurveillance-candida-auris-2-tales-salmonella-spp)3. Click Here to get your PACE credits (Expiration date – 10/25/2024): (labroots.com/credit/pace-credits/7539/cert) Labroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
Optimising Cell Line Development for Bioprocessing Labroots 2022-10-25 | Presented By: Sami Ullah, PhDSpeaker Biography: Dr. Sami Ullah is working as a scientist in the cancer biology group at one of Europe’s largest cell line repositories, the DSMZ (German collection of cell cultures and microorganisms). He has a Ph.D. in Biotechnology where he focused on developing in vitro and in vivo models for diseases mechanism studies and drug delivery. Later, he focused on the development of cell culture models with the idea to replicate the in vivo conditions in vitro. At DSMZ, he is developing high-throughput 3D cell culture systems for different types of cancers and developing a pipeline to transfer the available cell cultures to serum-free cell culture.Webinar: Optimising Cell Line Development for BioprocessingWebinar Abstract: In the last decades, the upstream processing in biopharma industry has been revolutionized regarding the production of bioactive materials such as monoclonal antibodies, proteins and biotherapeutics. More and more cell lines are produced with an aim to increase the productivity and quality of biologics produced. For instance, the mammalian cell lines have gained extreme importance in production of recombinant proteins for different applications. This is in general because of the fact that mammalian cell lines allow proper protein folding and post-translational modification. Although, the process itself starts with introduction of a “gene of interest” in to the cell line, there are a number of factors which needs to be taken in to account before claiming the cell line for biologics production. Earn PACE Credits:1. Make sure you’re a registered member of Labroots (labroots.com)2. Watch the webinar on YouTube or on the Labroots Website (labroots.com/webinar/optimising-cell-line-development-bioprocessing)3. Click Here to get your PACE credits (Expiration date – 04/06/2024): labroots.com/credit/pace-credits/7149/certLabroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
Model Assisted Design, Transfer and Scale Up of an Antibody Producing Cell Culture Process Labroots 2022-10-25 | Presented By: Prof. Dr.-Ing. Habil. Ralf PörtnerSpeaker Biography: Prof. Dr.-Ing. Ralf Pörtner is a senior research associate and group leader at Technical University Hamburg, Institute of Bioprocess and Biosystems Engineering and Honorary Professor at TH Mittelhessen University of Applied Sciences, Giessen. The main research interests of Prof. Pörtner are development and optimization of bioreactor techniques and process strategies, in particular for cell cultures and microbial reactions, including model-based control concepts, and tissue engineering. He has in published less than 140 peer-reviewed papers (H-index of 36).Webinar: Model-Assisted Design, Transfer and Scale-Up of an Antibody-Producing Cell Culture ProcessWebinar Abstract: Biopharmaceuticals produced with mammalian cells are the key drivers for the medication of former untreatable diseases. The development of their production processes is still challenging because of regulatory requirements and complex and sophisticated process strategies. Development and scale-up of cell culture processes are still mainly based on expert knowledge, one-factor-at-a-time or experimantal Design of Experiments approaches. This significantly increases the time and costs and simultaneously limits the obtained knowledge.Earn PACE Credits:1. Make sure you’re a registered member of Labroots (labroots.com)2. Watch the webinar on YouTube or on the Labroots Website (labroots.com/webinar/model-assisted-design-transfer-scale-up-antibody-producing-cell-culture-process)3. Click Here to get your PACE credits (Expiration date – 04/06/2024): labroots.com/credit/pace-credits/7153/certLabroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
Leveraging Microscale Automated Bioreactors for the Design and Optimization of Microbial Cell... Labroots 2022-10-25 | Presented By: Leonardo Rios Solis, PhDSpeaker Biography: Dr Rios did his PhD in the Biochemical Engineering Department at University College London where he worked in microscale automated tools to optimize and model synthetic de novo enzymatic pathways. Dr Rios then won a prestigious postdoctoral fellowship from the University of California Berkeley, where he focused in applying synthetic biology tools to engineer yeast and E. coli strains using multiplex CRISPR Cas9 to produce biofuels and pharmaceuticals. Webinar: Leveraging Microscale Automated Bioreactors for the Design and Optimization of Microbial Cell Factories for the Production of Anticancer Drugs TaxolWebinar Abstract: Currently over 95 % of pharmaceutical products and transport fuels are derived from petroleum. Sustainable alternatives are critical to achieving net-zero emissions without detriment to quality of life. The blockbuster chemotherapeutic Taxol is naturally scarce, difficult to extract, and their chemical complexity often hinders total synthesis. Industrial scale production is therefore a monumental challenge. Microbial biosynthesis is an alternative, sustainable production route, which has been widely reported at laboratory scale.Earn PACE Credits:1. Make sure you’re a registered member of Labroots (labroots.com)2. Watch the webinar on YouTube or on the Labroots Website (labroots.com/webinar/leveraging-microscale-automated-bioreactors-design-optimization-microbial-cell-factories-production)3. Click Here to get your PACE credits (Expiration date – 04/06/2024): labroots.com/credit/pace-credits/7170/certLabroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
Introduction to Next Generation Bioanalytics Development Labroots 2022-10-25 | Presented By: Nagarjun Kasaraneni, PhDSpeaker Biography: Nagarjun is a Scientist in Technical Operations at Sana Biotechnology (Cambridge, MA). He completed his PhD in Medical Sciences at Texas A&M University (Texas), where he worked on development of a universal lentiviral vector platform for different gene therapy applications. After his graduate school, he joined Lonza (Houston), as a research intern and worked on developing cell lines for high titer productivity of different viral vectors. Nagarjun currently works on analytical method development to develop fit for purpose genomic assays to characterize viral vectors across Sana gene therapy platforms.Webinar: Introduction to Next Generation Bioanalytics DevelopmentWebinar Abstract: Viral Vector gene therapy has been the focus of intense research driven by the safety profile and several clinical breakthroughs. As of March 2022, there are two viral vector gene therapies approved and many are in active clinical trials. The expected increase in demand for specific viral vectors still poses many challenges. The current talk tries to summarize the key aspects related to Research and development needs and Chemistry, Manufacturing and Control (CMC) efforts to help this growing demand. We will primarily discuss applying the different orthogonal bioanalytics to identify, monitor and control Critical Quality Attributes (CQAs) during the process development activity.Earn PACE Credits:1. Make sure you’re a registered member of Labroots (labroots.com)2. Watch the webinar on YouTube or on the Labroots Website (labroots.com/webinar/introduction-generation-bioanalytics-development)3. Click Here to get your PACE credits (Expiration date – 04/06/2024): labroots.com/credit/pace-credits/7213/certLabroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
In Silico Scale Up Reduce Your Experimental Effort with Reactor Simulation Labroots 2022-10-25 | Presented By: Christian Witz, Ph.D.Speaker Biography: Christian Witz did his bachelor and master in the field of chemical process engineering. In his Ph.D. and Post-Doc phase Witz created a novel simulation program for aerated and stirred bioreactors. Based on this technology, he founded the spin-off “SimVantage”.Webinar: In-Silico Scale-Up: Reduce Your Experimental Effort with Reactor SimulationWebinar Abstract: The design, optimization and troubleshooting of industrial bioprocesses are still largely based on empirical knowledge. Thus, the goal and motivation is to base these processes on a comprehensive view of the physical and chemical processes within the reactor. By applying the latest numerical algorithms and graphical processing units (graphics cards), the inner workings of the bioreactor can be studied in detail for the first time. This lays the foundation for new apparatus designs as well as for optimization of operating parameters and process characterization on the computer. Using the example of aerated stirred bioreactors, I will show how this new simulation tool integrates and accelerates your workflow from lab to market.Earn PACE Credits:1. Make sure you’re a registered member of Labroots (labroots.com)2. Watch the webinar on YouTube or on the Labroots Website (labroots.com/webinar/in-silico-scale-up-reduce-experimental-effort-reactor-simulation)3. Click Here to get your PACE credits (Expiration date – 04/06/2024): labroots.com/credit/pace-credits/7093/certLabroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
From Experiments, Data, Hybrid Models, and Digital Twins Several Up and Downstream Success... Labroots 2022-10-25 | Presented By: Dr. Mark DürkopSpeaker Biography: With more than 10 years of experience, Mark is a passionate expert in the field of biopharmaceutical process development. He worked together with several Top25 Pharma companies in different projects targeting their needs in process development and understanding. Together with his team, he is developing a hybrid modeling software for both up and downstream processes. This software utilizes AI applied to process data and first principle models (hybrid models) to quickly predict critical quality attributes (CQAs) from critical process parameters (CPPs). Hereby, bioprocess development and characterization are accelerated significantly while simultaneously a better process understanding is gathered. From this research project, the company Novasign was founded in 2019 offering this unique software solution.Webinar: From Experiments, Data, Hybrid Models, and Digital Twins. Several Up- and Downstream Success Stories Highlighting the Benefits of Using Advanced Process ModelingWebinar Abstract: The application of modeling tools to better understand and control bioprocess development and manufacturing has become a hot topic within the last few years. However, what do we actually need? Is it just about data and powerful modeling algorithms, or is there more to consider to accurately describe a process and transfer the knowledge and model structure from early-stage development until manufacturing?Earn PACE Credits:1. Make sure you’re a registered member of Labroots (labroots.com)2. Watch the webinar on YouTube or on the Labroots Website (labroots.com/webinar/experiments-data-hybrid-models-digital-twins-up-downstream-success-stories-highlighting-benefits-usi-2)3. Click Here to get your PACE credits (Expiration date – 04/06/2024): labroots.com/credit/pace-credits/7171/certLabroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
Keynote Presentation A Generic Manufacturing Platform for Downstream Processing on Non mab Proteins Labroots 2022-10-25 | Presented By: Alois Jungbauer, PhDSpeaker Biography: Professor Alois Jungbauer received his PhD in Food Technology and Biotechnology from BOKU. He serves as a professor at the Department of Biotechnology at BOKU. He teaches Protein Technology and Downstream Processing and Bioprocess Engineering and is study director of the Ph.D. program Bioprocess Engineering. He also acts as area head of Bioprocessing Engineering and Deputy Director of Research in the Austrian Centre of Industrial Biotechnology.Webinar: Keynote Presentation: A Generic Manufacturing Platform for Downstream Processing on Non-mab ProteinsWebinar Abstract: The vast structural diversity of proteins is responsible for their functional versatility, but also makes their expression and purification a demanding task. Tagging proteins with affinity tags can overcome the complexity of conventional purification by enabling affinity chromatography. An overview will be given for the purification of tagged proteins and then a purification system using a circular permutated caspase will be described in detail. It has been developed for process fusion protein processing to generate an authentic N-terminus for all 20 amino acids. The system employs widely available affinity chromatography resins, and a simple process can be used regardless of the specific nature of the protein of interest.Earn PACE Credits:1. Make sure you’re a registered member of Labroots (labroots.com)2. Watch the webinar on YouTube or on the Labroots Website (labroots.com/webinar/keynote-presentation-generic-manufacturing-platform-downstream-processing-non-mab-proteins)3. Click Here to get your PACE credits (Expiration date – 04/06/2024): labroots.com/credit/pace-credits/7195/certLabroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
Keynote Presentation Continuous Bioprocessing New Challenges and Opportunities for Membrane... Labroots 2022-10-25 | Presented By: Andrew L. Zydney, PhDSpeaker Biography: Dr. Andrew L. Zydney is the Bayard D. Kunkle Chair and Professor of Chemical Engineering at The Pennsylvania State University. He also serves as Director of the Penn State site in the Membrane Science, Engineering, and Technology (MAST) Center. Dr Zydney was Head of the Chemical Engineering Department from 2004-2014 and was he the founding Director of the Penn State Center of Excellence in Industrial Biotechnology in 2017. Professor Zydney's research is focused on the application of membranes in bioprocessing, including the purification of monoclonal antibodies, vaccines, and gene therapy agents with more than 260 publications in these areas.Webinar: Keynote Presentation: Continuous Bioprocessing - New Challenges and Opportunities for Membrane TechnologyWebinar Abstract: There is growing interest in the development of integrated continuous bioprocesses for the production of important biotherapeutics due to the potential for enhanced productivity, greater flexibility, and improved product quality. The transition from batch to continuous bioprocessing requires a major re-thinking of the downstream purification process, creating exciting new opportunities for membrane technology. This talk will focus on the use of continuous countercurrent staged membrane systems for initial product capture and for final formulation.Earn PACE Credits:1. Make sure you’re a registered member of Labroots (labroots.com)2. Watch the webinar on YouTube or on the Labroots Website (labroots.com/webinar/keynote-presentation-continuous-bioprocessing-challenges-opportunities-membrane-technology)3. Click Here to get your PACE credits (Expiration date – 04/06/2024): labroots.com/credit/pace-credits/7180/certLabroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
Panel Presentation - An Overview of Gene Therapy Manufacturing Development through Commercial... Labroots 2022-10-25 | Presented By: Kevin G. McGarry, Jr., PhD and Samir Acharya, PhDSpeaker Biography: Kevin G. McGarry, Jr., Ph.D. currently serves as a manager on the Analytical Development team. He has 14+ years of experience specializing in the development, qualification, validation, and implementation of both in vitro and in vivo assays for the evaluation of gene therapies/biologics and other therapeutics.Dr. Samir Acharya, Associate Director of Process Development is responsible for Process and Platform Development, their optimization, characterization and technology transfer. Prior to Andelyn Biosciences, he has over 25 years of research experience in mechanisms of genomic instability and pathways of cell survival and proliferation.Webinar: Panel Presentation: An Overview of Gene Therapy Manufacturing: Development through Commercial ProductionWebinar Abstract: The field of gene therapy is young and rapidly evolving, with new information discovered every day and an ever-increasing number of novel therapies entering various phases of clinical trials. For over 15 years, Nationwide Children’s Hospital in Columbus, Ohio, has performed as a research leader in the gene therapy field, and Andelyn Biosciences was born of this expertise in 2020. As gene therapy continues to grow, scientists must continue to learn from the rich, albeit recent, history and consider new insights from early developmental research through commercial production of a gene therapy product. There are high-level points and potential challenges to consider, including early development and selection of a viral vector, vector design, strategies for upstream and downstream process and platform development, in-process characterization of a product, and scalability, among others. This overview will cover these topics through the process of bringing a new product to the clinic.Earn PACE Credits:1. Make sure you’re a registered member of Labroots (labroots.com)2. Watch the webinar on YouTube or on the Labroots Website (labroots.com/webinar/panel-presentation-overview-gene-therapy-manufacturing-development-commercial-production)3. Click Here to get your PACE credits (Expiration date – 04/06/2024): labroots.com/credit/pace-credits/7218/certLabroots on Social:Facebook: facebook.com/LabRootsIncTwitter: twitter.com/LabRootsLinkedIn: linkedin.com/company/labrootsInstagram: instagram.com/labrootsincPinterest: pinterest.com/labrootsSnapChat: labroots_inc
