What is a Protein? (from PDB-101) RCSBProteinDataBank 2017-11-20 | Proteins play countless roles throughout the biological world, from catalyzing chemical reactions to building the structures of all living things. Despite this wide range of functions, all proteins are made out of the same twenty one amino acids, but combined in different ways. The way these twenty amino acids are arranged dictates the folding of the protein into its unique final shape. Since protein function is based on the ability to recognize and bind to specific molecules, having the correct shape is critical for proteins to do their jobs correctly.Visit PDB-101 (http://pdb101.rcsb.org/learn/videos/what-is-a-protein-video) to download related teaching and learning materials, including a presentation summarizing the content of this video and a flyer with abbreviated version of the content.Closed captions are available in English, Italian, and Romanian. To contribute subtitles in your language, use this link: http://www.youtube.com/timedtext_video?v=wvTv8TqWC48&ref=shareStory by: David S. Goodsell and Maria VoigtAnimation and Editing by: Maria VoigtNarration by: Brian Hudson
Seasons Greetings from the RCSB PDB RCSBProteinDataBank 2023-12-21 | Celebrate the holidays with PDB-themed wrapping paper/virtual meeting backgrounds. Visit https://pdb101.rcsb.org/news/656e3114d78e004e766a96c3 to learn more about the proteins used in this animation and download the resources.
Leveraging RCSB PDB APIs for Bioinformatics Analyses and Machine Learning Part 2 RCSBProteinDataBank 2023-10-23 | In this guided session, you will work with an example of a typical workflow that integrate Data and Search APIs and then apply the knowledge to your own specific problem.Please visit the PDB-101 Training Course page for access to the slides, documents, and other training materials: https://pdb101.rcsb.org/train/training-events/apiWho Should Attend* Bioinformatics or structural biology researchers* Researchers that need to cross-reference PDB and data from other resources* Anyone interested in large scale analyses of structural data (experimental or computational)
Leveraging RCSB PDB APIs for Bioinformatics Analyses and Machine Learning RCSBProteinDataBank 2023-10-12 | The lectures in this session will introduce you to the two main RCSB PDB APIs: Data API and Search API.Please visit the PDB-101 Training Course page for access to the slides, documents, and other training materials: https://pdb101.rcsb.org/train/training-events/apiTimestamps:00:00:00 Welcome00:07:55 Introduction to RCSB PDB APIs and data schemas00:37:59 Data API01:09:10 Search API01:41:36 Search and Data API hands-on teaserAfter completion of this session, you will* Understand the data structure and its relation to the PDBx/mmCIF dictionary and external data* Become familiarized with the two available interfaces in the Data API: GraphQL and REST* Write search queries with one or multiple search conditions to find PDB identifiers* Be familiar with search services beyond text: sequence, seqmotif, structure, chemical, strucmotif* Become acquainted with the Python client for Search API
Evolution of the Insulin Gene RCSBProteinDataBank 2023-08-31 | This video introduces you to insulin family proteins and the evolution of the insulin gene.
Molecular Machinery: A Tour RCSBProteinDataBank 2023-08-29 | This video introduces the Molecular Machinery interactive poster available from PDB-101 at https://cdn.rcsb.org/pdb101/molecular-machinery/.
Insulin Biosynthesis RCSBProteinDataBank 2023-08-18 | This video describes how insulin is made in pancreatic beta cells and processed to form the functional molecule.0:00 Insulin Biosynthesis0:31 What is Insulin?1:40 Pre-pro-insulin3:39 Summary
What is Cancer? RCSBProteinDataBank 2023-06-27 | This video discusses what cancer is, why we have cancer, how it is diagnosed and treated.Chapters0:00 A Cancer Expert Talks to Students0:18 What is Cancer?2:40 Maintaining Balance4:14 Cell growth and Cancer7:40 Autonomous and Immortal8:25 Diagnosis of Cancer9:00 Classification and Treatment
Breast Cancer Chess Championship: Trastuzumab vs HER2 Receptor RCSBProteinDataBank 2023-05-16 | Winner of the Judge’s Award First Place and Viewer's Choice Award in the 2023 RCSB PDB Video Challenge for High School Students “Molecular Mechanisms of Targeted Cancer Therapies”By Joan Ashreya Mare, Grace Lee, and Ananya VakkalankaWest Windsor-Plainsboro High School South, West Windsor, New JerseyTeam Advisor: Mrs. Meenakshi BhattacharyaVisit https://pdb101.rcsb.org/ to learn more
Fighting Cancer by Targetting G12C RCSBProteinDataBank 2023-05-16 | Winner of the Judge’s Award Second Place in the 2023 RCSB PDB Video Challenge for High School Students “Molecular Mechanisms of Targeted Cancer Therapies”By Amanda Nguyen, Kristen Ngo, and Gavin GonzalesMira Mesa High School, San Diego, CATeam Advisor: Mrs. Lisa YonedaVisit https://pdb101.rcsb.org/ to learn more
Investigating the Role of VEGF in Targeted Therapy for Cancer RCSBProteinDataBank 2023-05-16 | Winner of the Judge’s Award Third Place in the 2023 RCSB PDB Video Challenge for High School Students “Molecular Mechanisms of Targeted Cancer Therapies”By Victoria SilvaJericho High School, Jericho, NYTeam Advisor: Mrs. Samantha SforzaVisit https://pdb101.rcsb.org/ to learn more
Understanding PDBx/mmCIF: Course Introduction RCSBProteinDataBank 2023-05-09 | This course is designed to help users understand the basics of PDBx/mmCIF data dictionary and file format that underpin the archiving of experimentally determined three-dimensional biostructures in the PDB. After completing of this course, you will be able to use software tools for generating, editing, and visualizing PDBx/mmCIF files, understand PDBx/mmCIF dictionary extensions (including ModelCIF for computed structure models), and parse data from PDBx/mmCIF files for your research.Access the full course and supplementary materials at https://pdb101.rcsb.org/train/training-events/mmcif.Presenter:Stephen K. Burley, Director, RCSB Protein Data Bank
Introduction and course objectives RCSBProteinDataBank 2023-05-09 | This course is designed to help users understand the basics of PDBx/mmCIF data dictionary and file format that underpin the archiving of experimentally determined three-dimensional biostructures in the PDB. After completing of this course, you will be able to use software tools for generating, editing, and visualizing PDBx/mmCIF files, understand PDBx/mmCIF dictionary extensions (including ModelCIF for computed structure models), and parse data from PDBx/mmCIF files for your research.Access the full course and supplementary materials at https://pdb101.rcsb.org/train/training-events/mmcif.Presenter:Gregg Crichlow, Biocurator, RCSB PDB, Rutgers University
PDBx/mmCIF format - Not your parents’ legacy PDB format RCSBProteinDataBank 2023-05-09 | This course is designed to help users understand the basics of PDBx/mmCIF data dictionary and file format that underpin the archiving of experimentally determined three-dimensional biostructures in the PDB. After completing of this course, you will be able to use software tools for generating, editing, and visualizing PDBx/mmCIF files, understand PDBx/mmCIF dictionary extensions (including ModelCIF for computed structure models), and parse data from PDBx/mmCIF files for your research.Access the full course and supplementary materials at https://pdb101.rcsb.org/train/training-events/mmcif.Presenter:Ezra Peisach, Scientific Software Developer/PDBx mmCIF Dictionary Manager
PDBx/mmCIF data files - Lifting the lid off the black box RCSBProteinDataBank 2023-05-09 | This course is designed to help users understand the basics of PDBx/mmCIF data dictionary and file format that underpin the archiving of experimentally determined three-dimensional biostructures in the PDB. After completing of this course, you will be able to use software tools for generating, editing, and visualizing PDBx/mmCIF files, understand PDBx/mmCIF dictionary extensions (including ModelCIF for computed structure models), and parse data from PDBx/mmCIF files for your research.Access the full course and supplementary materials at https://pdb101.rcsb.org/train/training-events/mmcif.Presenter:Brian Hudson, Biocurator, RCSB PDB, Rutgers University
Programmatic data access and analysis using PDBx/mmCIF files, Part 1 RCSBProteinDataBank 2023-05-09 | This course is designed to help users understand the basics of PDBx/mmCIF data dictionary and file format that underpin the archiving of experimentally determined three-dimensional biostructures in the PDB. After completing of this course, you will be able to use software tools for generating, editing, and visualizing PDBx/mmCIF files, understand PDBx/mmCIF dictionary extensions (including ModelCIF for computed structure models), and parse data from PDBx/mmCIF files for your research.Access the full course and supplementary materials at https://pdb101.rcsb.org/train/training-events/mmcif.Presenter:Irina Persikova, Biocuration Lead Deputy, RCSB PDB, Rutgers University
Programmatic data access and analysis using PDBx/mmCIF files, Part 2 RCSBProteinDataBank 2023-05-09 | This course is designed to help users understand the basics of PDBx/mmCIF data dictionary and file format that underpin the archiving of experimentally determined three-dimensional biostructures in the PDB. After completing of this course, you will be able to use software tools for generating, editing, and visualizing PDBx/mmCIF files, understand PDBx/mmCIF dictionary extensions (including ModelCIF for computed structure models), and parse data from PDBx/mmCIF files for your research.Access the full course and supplementary materials at https://pdb101.rcsb.org/train/training-events/mmcif.Presenter:Chenghua Shao, Biocurator, Scientific Software Developer/KPI Evaluator, RCSB PDB, Rutgers University
Python Scripting for Biochemistry &Molecular Biology - Part 2 Introduction RCSBProteinDataBank 2023-05-04 | This is the second part of the IQB Crash Course designed to introduce life scientists to the power and flexibility of solving problems with Python. This course offers a brief review of Python and the Jupyter Notebook environment first, later diving into working with Python libraries and various types of data.Access the full course: Part 1:https://pdb101.rcsb.org/train/training-events/pythonPart 2:https://pdb101.rcsb.org/train/training-events/python2
Python Primer: Review of Python and the Jupyter Notebook environment RCSBProteinDataBank 2023-05-04 | This is the second part of the IQB Crash Course designed to introduce life scientists to the power and flexibility of solving problems with Python. This course offers a brief review of Python and the Jupyter Notebook environment first, later diving into working with Python libraries and various types of data. Access the full course: Part 1: https://pdb101.rcsb.org/train/training-events/python Part 2: https://pdb101.rcsb.org/train/training-events/python2
Nonlinear regression: Creating the Pandas DataFrame RCSBProteinDataBank 2023-05-04 | This is the second part of the IQB Crash Course designed to introduce life scientists to the power and flexibility of solving problems with Python. This course offers a brief review of Python and the Jupyter Notebook environment first, later diving into working with Python libraries and various types of data. Access the full course: Part 1: https://pdb101.rcsb.org/train/training-events/python Part 2: https://pdb101.rcsb.org/train/training-events/python2
Nonlinear Regression: Curve Fitting RCSBProteinDataBank 2023-05-04 | This is the second part of the IQB Crash Course designed to introduce life scientists to the power and flexibility of solving problems with Python. This course offers a brief review of Python and the Jupyter Notebook environment first, later diving into working with Python libraries and various types of data. Access the full course: Part 1: https://pdb101.rcsb.org/train/training-events/python Part 2: https://pdb101.rcsb.org/train/training-events/python2
Extracting data from mmCIF files using the Biopython library RCSBProteinDataBank 2023-05-04 | This is the second part of the IQB Crash Course designed to introduce life scientists to the power and flexibility of solving problems with Python. This course offers a brief review of Python and the Jupyter Notebook environment first, later diving into working with Python libraries and various types of data. Access the full course: Part 1: https://pdb101.rcsb.org/train/training-events/python Part 2: https://pdb101.rcsb.org/train/training-events/python2
Extracting data from mmCIF files using the RCSB PDB API RCSBProteinDataBank 2023-05-04 | This is the second part of the IQB Crash Course designed to introduce life scientists to the power and flexibility of solving problems with Python. This course offers a brief review of Python and the Jupyter Notebook environment first, later diving into working with Python libraries and various types of data. Access the full course: Part 1: https://pdb101.rcsb.org/train/training-events/python Part 2: https://pdb101.rcsb.org/train/training-events/python2
Multiple Views in a Mol* Session RCSBProteinDataBank 2023-02-14 | This video shows how to create, save, and open Mol* sessions with multiple saved views. Share saved sessions with students or with researchers for collaboration.Learn more about using Mol* at https://www.rcsb.org/docs/3d-viewers/mol*/getting-started
Exploring the PD-1/PD-L1 pathway using Data, Tools, and Resources from RCSB.org RCSBProteinDataBank 2023-02-08 | Based on case studies presented in http://doi.org/10.1002/pro.448200:00: Intro to PD-1/PD-L101:45: Exploring PDB ID 5jxe - Structure Summary page04:35 How Pembrolizumab Disrupts PD-1:PD-L1 Binding 05:40 Compare structures07:28 Other Therapeutic Anti-PD-1 AntibodiesLearn more about Pembrolizumab (https://pdb101.rcsb.org/motm/204) and other cancer therapy approaches on PDB-101 (https://pdb101.rcsb.org/).
Introduction to Python and to Jupyter Notebooks RCSBProteinDataBank 2023-01-26 | Lesson 1/4 of "Python Scripting for Biochemistry & Molecular Biology" Crash Course.This workshop makes the life scientists acquaintant with the power and flexibility of solving problems with Python by introducing specific coding skills, as well as providing insight into the broader array of open-access resources and libraries that are available for scientific computation.
Reading and Writing Files using Python and Jupiter Notebooks RCSBProteinDataBank 2023-01-26 | Lesson 2/4 of workshop "Python Scripting for Biochemistry & Molecular Biology".This workshop makes the life scientists acquaintant with the power and flexibility of solving problems with Python by introducing specific coding skills, as well as providing insight into the broader array of open-access resources and libraries that are available for scientific computation.
Processing Multiple Files RCSBProteinDataBank 2023-01-26 | Lesson 3/4 of the workshop "Python Scripting for Biochemistry & Molecular Biology".This workshop makes the life scientists acquaintant with the power and flexibility of solving problems with Python by introducing specific coding skills, as well as providing insight into the broader array of open-access resources and libraries that are available for scientific computation.
Visualizing PDB structures in the Jupyter Notebooks RCSBProteinDataBank 2023-01-26 | Python Scripting for Biochemistry & Molecular Biology.This workshop makes the life scientists acquaintant with the power and flexibility of solving problems with Python by introducing specific coding skills, as well as providing insight into the broader array of open-access resources and libraries that are available for scientific computation.
Seasons Greetings from the RCSB PDB RCSBProteinDataBank 2022-12-22 | A major 2022 RCSB.org release was a feature that enables users to explore Computed Structure Models (CSMs) alongside experimentally-determined structures from the PDB archive (https://www.rcsb.org/news/6304ee57707ecd4f63b3d3db).This animation celebrates this milestone by highlighting PDB structure 7VMF (https://www.rcsb.org/structure/7VMF), a histone acetyltransferase from Arabidopsis thaliana in dark blue. The CSM (https://www.rcsb.org/structure/AF_AFQ56WH4F1) created based on the corresponding UniProt sequence Q56WH4 (https://www.rcsb.org/groups/sequence/polymer_entity/Q56WH4) is then displayed with high confidence regions shown in ribbon representation in cyan and lower confidence regions shown in ball and stick representation.
Accessing Experimental Structures from the PDB RCSBProteinDataBank 2022-11-29 | A virtual course ‘Using KBase to access PDB Structures and Computed Structure Models’ was held on Thursday November 10, 2022. The participants had the opportunity to learn about the protein structure-related tools, visualizations, and workflows that have been integrated into DOE KBase. The talk synopses and the summary of the Q and A are available here:https://go.rutgers.edu/88xapxdeUse this link to access the full coursehttps://www.youtube.com/playlist?list=PLHib7JgKNUUf8Z8jSK57FsJrms94wpaL0Presenter: Dennis Piehl, Ph.D. - RCSB Protein Data Bank, Rutgers University Title: Accessing Experimental Structures from the PDB
Making the Best use of Protein Structure Data in KBase and PDB RCSBProteinDataBank 2022-11-29 | A virtual course ‘Using KBase to access PDB Structures and Computed Structure Models’ was held on Thursday November 10, 2022. The participants had the opportunity to learn about the protein structure-related tools, visualizations, and workflows that have been integrated into DOE KBase. The talk synopses and the summary of the Q and A are available here:https://go.rutgers.edu/88xapxdeUse this link to access the full coursehttps://www.youtube.com/playlist?list=PLHib7JgKNUUf8Z8jSK57FsJrms94wpaL0Presenter: Christopher Henry, Ph.D. - KBase, Argonne National LaboratoryTitle: Making the Best use of Protein Structure Data in KBase and PDB
KBase Apps for Protein Structure Data Communication and Integration with RCSB PDB RCSBProteinDataBank 2022-11-29 | A virtual course ‘Using KBase to access PDB Structures and Computed Structure Models’ was held on Thursday November 10, 2022. The participants had the opportunity to learn about the protein structure-related tools, visualizations, and workflows that have been integrated into DOE KBase. The talk synopses and the summary of the Q and A are available here:https://go.rutgers.edu/88xapxdeUse this link to access the full coursehttps://www.youtube.com/playlist?list=PLHib7JgKNUUf8Z8jSK57FsJrms94wpaL0Presenter: Qizhi Zhang, Ph.D. - KBase, Argonne National Laboratory Title: KBase Apps for Protein Structure Data Communication and Integration with RCSB PDB
Introduction to Mol* (MolStar) Molecular Graphics System RCSBProteinDataBank 2022-11-29 | A virtual course ‘Using KBase to access PDB Structures and Computed Structure Models’ was held on Thursday November 10, 2022. The participants had the opportunity to learn about the protein structure-related tools, visualizations, and workflows that have been integrated into DOE KBase. The talk synopses and the summary of the Q and A are available here:https://go.rutgers.edu/88xapxdeUse this link to access the full coursehttps://www.youtube.com/playlist?list=PLHib7JgKNUUf8Z8jSK57FsJrms94wpaL0Presenter: Shuchismita Dutta, Ph.D. - RCSB Protein Data Bank, Rutgers University Title: Introduction to the Virtual Crash Course on Using KBase to access PDB Structures and Computed Structure Models
Accessing Computed Structure Models generated using AlphaFold2 or RoseTTAFold(2) RCSBProteinDataBank 2022-11-29 | A virtual course ‘Using KBase to access PDB Structures and Computed Structure Models’ was held on Thursday November 10, 2022. The participants had the opportunity to learn about the protein structure-related tools, visualizations, and workflows that have been integrated into DOE KBase. The talk synopses and the summary of the Q and A are available here:https://go.rutgers.edu/88xapxdeUse this link to access the full coursehttps://www.youtube.com/playlist?list=PLHib7JgKNUUf8Z8jSK57FsJrms94wpaL0Presenter: Brinda Vallat, Ph.D. - RCSB Protein Data Bank, Rutgers University Title: Accessing Computed Structure Models generated using AlphaFold2 or RoseTTAFold(2)
Protein Candidates from Function Queries in KBase RCSBProteinDataBank 2022-11-29 | A virtual course ‘Using KBase to access PDB Structures and Computed Structure Models’ was held on Thursday November 10, 2022. The participants had the opportunity to learn about the protein structure-related tools, visualizations, and workflows that have been integrated into DOE KBase. The talk synopses and the summary of the Q and A are available here:https://go.rutgers.edu/88xapxdeUse this link to access the full coursehttps://www.youtube.com/playlist?list=PLHib7JgKNUUf8Z8jSK57FsJrms94wpaL0Presenter: Janaka N. Edirisinghe, Ph.D. - KBase, Argonne National Laboratory Title: Protein Candidates from Function Queries in KBase
KBase/RCSB PDB Crash Course Objectives RCSBProteinDataBank 2022-11-29 | A virtual course ‘Using KBase to access PDB Structures and Computed Structure Models’ was held on Thursday November 10, 2022. The participants had the opportunity to learn about the protein structure-related tools, visualizations, and workflows that have been integrated into DOE KBase. The talk synopses and the summary of the Q and A are available here:https://go.rutgers.edu/88xapxdeUse this link to access the full coursehttps://www.youtube.com/playlist?list=PLHib7JgKNUUf8Z8jSK57FsJrms94wpaL0Presenter: Christopher Henry, Ph.D. - KBase, Argonne National Laboratory Title: Review of Joint DOE KBase/RCSB PDB Crash Course Objectives
Introduction | Using KBase to Access Protein Structures and Models RCSBProteinDataBank 2022-11-29 | A virtual course ‘Using KBase to access PDB Structures and Computed Structure Models’ was held on Thursday November 10, 2022. The participants had the opportunity to learn about the protein structure-related tools, visualizations, and workflows that have been integrated into DOE KBase. The talk synopses and the summary of the Q and A are available here:https://go.rutgers.edu/88xapxdeUse this link to access the full coursehttps://www.youtube.com/playlist?list=PLHib7JgKNUUf8Z8jSK57FsJrms94wpaL0Presenter: Stephen K. Burley, Director, RCSB Protein Data Bank Title: Introduction to the Virtual Crash Course on Exploring the Computed Structure Models on RCSB.org
Exploring Computed Structure Models on RCSB.org - Introduction RCSBProteinDataBank 2022-10-27 | Presenter: Stephen K. Burley, Director, RCSB Protein Data BankTitle: Introduction to the Virtual Crash Course on Exploring the Computed Structure Models on RCSB.orgIn August 2022, the RCSB PDB enabled access to ~1 million Computed Structure Models (CSMs) from AlphaFoldDB and RoseTTAFold in addition to the ~200,000 experimentally-determined PDB structures on the RCSB.org website. On September 22, 2022 a Virtual Crash Course was held to inform the RCSB.org users how to search, visualize, and analyze CSMs alongside experimentally-determined PDB structures using the custom-developed RCSB PDB tools.
What is in a Computed Structure Model? Meet AlphaFold and RoseTTAFold RCSBProteinDataBank 2022-10-27 | Presenter: Brinda VallatScientific Software Developer/PDB-Dev Representative and ModelCIF ManagerRCSB PDB/Rutgers________In August 2022, the RCSB PDB enabled access to ~1 million Computed Structure Models (CSMs) from AlphaFoldDB and RoseTTAFold in addition to the ~200,000 experimentally-determined PDB structures on the RCSB.org website. On September 22, 2022 a Virtual Crash Course was held to inform the RCSB.org users how to search, visualize, and analyze CSMs alongside experimentally-determined PDB structures using the custom-developed RCSB PDB tools.
How do I find models? Simple Searching Case Study and intro to Structure Summary Pages RCSBProteinDataBank 2022-10-27 | Presenter:Shuchismita DuttaScientific Educational Development Lead and Documentation LeadRCSB PDB/RutgersIn August 2022, the RCSB PDB enabled access to ~1 million Computed Structure Models (CSMs) from AlphaFoldDB and RoseTTAFold in addition to the ~200,000 experimentally-determined PDB structures on the RCSB.org website. On September 22, 2022 a Virtual Crash Course was held to inform the RCSB.org users how to search, visualize, and analyze CSMs alongside experimentally-determined PDB structures using the custom-developed RCSB PDB tools.
Advanced Searching, Group Summary Pages, and 1D-3D Tool RCSBProteinDataBank 2022-10-27 | Presenter:Joan SeguraScientific Software Developer, RCSB PDB/UCSDIn August 2022, the RCSB PDB enabled access to ~1 million Computed Structure Models (CSMs) from AlphaFoldDB and RoseTTAFold in addition to the ~200,000 experimentally-determined PDB structures on the RCSB.org website. On September 22, 2022 a Virtual Crash Course was held to inform the RCSB.org users how to search, visualize, and analyze CSMs alongside experimentally-determined PDB structures using the custom-developed RCSB PDB tools.
Computed Structure Models: Confidence Levels in 3D Predictions RCSBProteinDataBank 2022-10-27 | Presenter:Chenghua ShaoScientific Software Developer/KPI EvaluatorRCSB PDB/RutgersIn August 2022, the RCSB PDB enabled access to ~1 million Computed Structure Models (CSMs) from AlphaFoldDB and RoseTTAFold in addition to the ~200,000 experimentally-determined PDB structures on the RCSB.org website. On September 22, 2022 a Virtual Crash Course was held to inform the RCSB.org users how to search, visualize, and analyze CSMs alongside experimentally-determined PDB structures using the custom-developed RCSB PDB tools.
Computed Structure Models: Visualization, Validation, and Alignments RCSBProteinDataBank 2022-10-27 | Presenter:Sebastian BittrichScientific Software DeveloperRCSB PDB/UCSDIn August 2022, the RCSB PDB enabled access to ~1 million Computed Structure Models (CSMs) from AlphaFoldDB and RoseTTAFold in addition to the ~200,000 experimentally-determined PDB structures on the RCSB.org website. On September 22, 2022 a Virtual Crash Course was held to inform the RCSB.org users how to search, visualize, and analyze CSMs alongside experimentally-determined PDB structures using the custom-developed RCSB PDB tools.
PDB50 at the ACA: Day 1 | John Rubinstein, Sick Kids Hospital RCSBProteinDataBank 2022-09-19 | Day 1 John Rubinstein (Sick Kid's Hospital, Toronto, Canada) Macromolecular Machines at Energized Membranes________________The 2021 American Crystallographic Association (ACA) Transactions Symposium (July 30-31, 2021) was dedicated to celebrating the manifold contributions of the PDB to fundamental biology, biomedicine, bioenergy, and bioengineering/biotechnology.Presentations from high profile experimental and computational structural biologists working in the United States, Canada, and South America were augmented by short round table discussions regarding future directions in structural biology and the important role that the Protein Data Bank can play in a rapidly changing landscape.Access all presentations from this meeting at rcsb.org (https://www.rcsb.org/pages/pdb50-meet..., or use this playlist for chronological recording of the full meeting including panel discussions and introductions (https://www.youtube.com/playlist?list...)
How Neurons Communicate: An Introduction to Neurotransmission and Action Potential (from PDB-101) RCSBProteinDataBank 2022-09-16 | The billions of neurons in our nervous system are constantly communicating. The signals they send to each other are responsible for our thoughts, sensations, and actions. Learn how ions, ion channels, receptors, and neurotransmitters work together to enable the neuronal signaling process.Learn more about neuronal signaling from PDB-101:Opioids and Pain Signaling: https://www.youtube.com/watch?v=ZmrDWIeX0TcNeuronal Signaling and Sodium-Potassium Pump: https://www.youtube.com/watch?v=ZKE8qK9UCrUPDB-101 resources on Cellular Signaling: https://pdb101.rcsb.org/browse/cellular-signaling
Building the Paper Model of DNA RCSBProteinDataBank 2022-09-16 | Learn how to build a 3D model of DNA using a free, downloadable PDF from PDB-101 https://pdb101.rcsb.org/learn/paper-models/dnaThis tutorial consists of 2 parts: a brief introduction to the DNA structure and a step-by-step tutorial on how to fold the PDB-101 paper template.Video Guide:0:00 Introduction to DNA1:22 Choosing the template1:51 Step 11:57 Step 22:23 Step 32:51 Step 43:15 Step 53:58 Step 64:24 Step 74:42 Step 8 (optional)
Construyendo el modelo de papel del ADN RCSBProteinDataBank 2022-09-16 | Aprenda a construir un modelo 3D de ADN utilizando un PDF descargable gratuito de PDB-101 https://pdb101.rcsb.org/learn/paper-models/dnaEste tutorial consta de 2 partes: una breve introducción a la estructura del ADN y un tutorial sobre cómo plegar la plantilla de papel PDB-101.Guía de vídeo:0:00 Introducción al ADN1:22 Elegir la plantilla1:51 Paso 11:57 Paso 22:23 Paso 32:51 Paso 43:15 Paso 53:58 Paso 64:24 Paso 74:42 Paso 8 (opcional)
p53 The Spell Checking Machine RCSBProteinDataBank 2022-05-17 | Winner of the Viewer's Choice Award in the 2022 RCSB PDB Video Challenge for High School Students “Molecular Mechanisms of Cancer”By Isabella Hakim, Kendall Archer, Olivia Spielman, Noah UmRiverdale Country School, Bronx, NYTeam Advisor: Mrs. Monica Murakami
Pika the p21: Protector of the Cell Cycle RCSBProteinDataBank 2022-05-17 | Winner of the Judge’s Award Third Place in the 2022 RCSB PDB Video Challenge for High School Students “Molecular Mechanisms of Cancer”By Jeslyn Choudhruy, He Xuan, Chloe ZhangJericho High School, NYTeam Advisor: Mrs. Serena McCalla
Menacing Mutations: Examining the Role of the RAS Oncogene in Cancer Development RCSBProteinDataBank 2022-05-17 | Winner of the Judge’s Award Second Place in the 2022 RCSB PDB Video Challenge for High School Students “Molecular Mechanisms of Cancer”By Xinyi ZhangSouth Brunswick High School, NJTeam Advisor: Mrs. Dana Armstrong
