Professor Craig Steinmaus shows how arsenic in drinking water causes cancer years after exposure EnviroHealthBerkeley 2014-02-27 | Professor Craig Steinmaus of the University of California Berkeley describes his research on arsenic exposures from drinking water in communities in Chile. He explains sources of arsenic and the many health effects that occur as a result of arsenic in drinking water, a common problem in many parts of the world. His current research is about children and how their exposures to arsenic may cause diseaseSuperfund.berkeley.edu
The Science of Climate Change Is Ever More Certain by Amy D Kyle EnviroHealthBerkeley 2015-02-14 | ...
How CIRCLE was created by Professor Patricia Buffler EnviroHealthBerkeley 2014-11-03 | Founding director Patricia Buffler explains how the Center for Integrative Research on Childhood Leukemia and the Environment was created in 2009, building on the California Childhood Leukemia Study.
Using HouseHold Dust to Measure Childrens Chemical Exposures in Homes EnviroHealthBerkeley 2014-11-03 | Presented by Todd Whitehead, investigator, University of California Berkeley, Center for Integrative Research on Childhood Leukemia and the Environment CIRCLE.berkeley.edu
The Importance of Epigenetics by Professor Joseph Wiemels of UCSF EnviroHealthBerkeley 2014-11-03 | circle.berkeley.edu
Professor Stephen Rappaport advocates for studies of the whole exposome. EnviroHealthBerkeley 2014-11-03 | circle.berkeley.edu
Catherine Metayer explains that pesticide exposure is associated with leukemia in children EnviroHealthBerkeley 2014-11-03 | Dr. CATHERINE METAYER of the Center for Integrative Research on Childhood Leukemia and the Environment at the University of California Berkeley shows that use of pesticides around homes, particularly during the prenatal period, may increase risk of childhood leukemias, particularly acute lymphoblastic leukemia or ALL. Pesticides may not be persistent enough to be detected in house dust collected years after exposure. Use of paint in the home after pregnancy may increase risk of ALL.circle.berkeley.edu
Founding of the Childhood Leukemia International Consortium EnviroHealthBerkeley 2014-11-03 | The Childhood Leukemia International Consortium brings together researchers from many countries to work together to better understand childhood leukemia. circle.berkeley.edu
Toxic chemicals used years ago are still found in dust in homes EnviroHealthBerkeley 2014-09-26 | Todd Whitehead of the University of California Berkeley explains his research on harmful contaminants that are found dust in homes. In this video, he explains the legacy of contaminants used in past years that still can be found today in dust in people’s homes.Center for Integrative Research on Childhood Leukemia and the Environment at the University of California Berkeley http://circle.berkeley.edu. Research support provided by from the National Institute of Environmental Health Sciences and the US Environmental Protection Agency. Presentations do not represent the views of these agencies.Produced by Amy D Kyle and Jon Schainker.
Todd Whitehead shows how to measure chemicals harmful to children in house dust EnviroHealthBerkeley 2014-09-26 | Dr. TODD WHITEHEAD explains how to measure chemicals in dust in houses. Some chemicals found in household dust are harmful to children. He works with samples collected by regular vacuum cleaners. Center for Integrative Research on Childhood Leukemia and the Environment at the University of California Berkeley http://circle.berkeley.edu. Produced by Amy D Kyle and Jon Schainker. Research support provided by from the National Institute of Environmental Health Sciences and the US Environmental Protection Agency. Presentations do not represent the views of these agencies.
Harmful chemicals are found in household dust EnviroHealthBerkeley 2014-09-26 | TODD WHITEHEAD shows that harmful chemicals including PCBs and other flame retardants are found in household dust. His studies show that such chemicals remain in dust for years. Children are at greatest risk because they play on floors and tend to ingest dirt and dust. He shows that flame retardants such as PCBs and PBDEs were found in dust samples collected during studies of causes of childhood leukemia. Center for Integrative Research on Childhood Leukemia and the Environment at the University of California Berkeley http://circle.berkeley.edu. Produced by Amy D Kyle and Jon Schainker. Research support provided by from the National Institute of Environmental Health Sciences and the US Environmental Protection Agency. Presentations do not represent the views of these agencies.
Sylvia Sanchez explains her work on how estrogens from the diet can affect disease EnviroHealthBerkeley 2014-02-28 | Superfund trainee Sylvia Sanchez uses a to study how biological molecules such as estrogens and androgens can affect receptors located in cells for hormones. Increased or changed activity at such receptors can contribute to disease or effects such as immune effects. She has shown increased activity at the receptors for hormones using a cell assay.
Dr. Fenna Sille studies effects of arsenic in drinking water on the immune system EnviroHealthBerkeley 2014-02-27 | Fenna Sille studies how arsenic affects the immune system, and whether this leads to several diseases. She focuses on exposures that occurred at a young age (early in life) and looks at cells found in blood and the lungs that are the first line of defense against toxic agents.
Professor Craig Steinmaus presents NEW results from studies in Chile of arsenic and cancer EnviroHealthBerkeley 2014-02-27 | Professor Steinmaus shows how arsenic in drinking water in a town in Chile led to cancer many years later. This presentation shows his results where bladder cancer was increased by seven times and lung cancer by four times due to exposure to arsenic many years before. Exposures at a young age led to higher likelihood of cancer. Combined arsenic and tobacco smoke exposure had synergistic relationships, leading to highest cancer chances. These high exposures were stopped in Chile but are found elsewhere. superfund.berkeley.edu
Dr Reuben Thomas studies benzene and other chemicals that cause leukemia EnviroHealthBerkeley 2014-02-27 | Dr Reuben Thomas is a statistician who studies how chemicals contribute to disease, particularly leukemia.
Brandon Gaytan shows how dieldrin may cause health effects EnviroHealthBerkeley 2014-02-27 | Brandon Gaytan and colleagues use yeast to study the toxicity of chemicals. Results from yeasts are also often applicable to humans because many of the genes are the same. This model helps also to understand susceptibility. Specific studies focus on the pesticide dieldrin. The method uses mutant forms that are missing a specific gene. Results from this show mutant forms that have growth defects and shed light on how the toxicity occurs. The studies show that dieldrin alters the availability of nutrients.
Daniel Medina Cleghorn introduces Core C of the Superfund Research Program at Berkeley EnviroHealthBerkeley 2014-02-27 | Core C is the analytical chemistry core for the Superfund Research Program. The core is focused on developing novel biomarkers and using them to better understand toxicological processes. This involves use of mass spectrometers and metabolomonics
Jay James invented a better way to measure mercury using nanoparticles EnviroHealthBerkeley 2014-02-26 | Arsenic is highly toxic and present in groundwater in many parts of the world. It has no smell or taste, so people cannot detect it on their own. Devices to measure arsenic in water have been expensive. Jay James and colleagues invented a new and better way to measure arsenic in water, leading to invention of a new monitoring device. This will help to protect people from unknowingly drinking water with a toxic pollutant. This work was supported by the Superfund Research Program at Berkeley.
Vanessa De La Rosa shows that the solvent TCE damages DNA in yeast EnviroHealthBerkeley 2014-02-26 | Vanessa De La Rosa is a graduate student and trainee in the Superfund Research Program at Berkeley. Working in the lab of Professor Chris Vulpe, her works shows that a solvent that is commonly found in groundwater at Superfund sites damages DNA in a yeast model. This suggests that the same may occur in humans. Next she will look at whether TCE damage contributes to cancer. superfund.berkeley.edu
Professor David Sedlak: reveals the next generation of Superfund contaminants EnviroHealthBerkeley 2014-02-26 | Professor David Sedlak explains how monitoring methods determine the types of contaminants that can be detected in environmental monitoring. Methods long in use have been successful in measuring chlorinated compounds such as TCE (trichloroethylene). However, other compounds such as those containing bromine and fluorine were not detected. Methods today do a better job at finding brominated and fluorinated compounds, and both of these pose potential environmental and health concerns. Professor Sedlak's hot new book is Water 4.0. http://www.water4point0.comHe is the Director of the Water Center http://bwc.berkeley.edu/home/ and a project leader for the Superfund Research Center at Berkeley.
Thomas Bruton explains new methods to speed groundwater cleanup EnviroHealthBerkeley 2014-02-26 | Thomas Bruton explains how he uses naturally occurring sediments to activate "persulfate" so that it can break down contaminants in groundwater. His experiments may lead to more effective and cheaper cleanup methods that do not require pumping water out of the ground. Sponsored by the Superfund Research Program at Berkeley
Environmental Exposures and Methylation Changes in Blood Spots by Joseph Wiemels EnviroHealthBerkeley 2013-10-26 | More information at http://circle.berkeley.eduProfessor Joseph Wiemels explains how environmental factors can cause changes in the way that people's DNA acts to control development and many other aspects of human biology. Such changes are called "epigenetic" because they involve addition and deletion of markers on the structures that support DNA in cells. In this presentation, Professor Wiemels highlights methodsto measure early epigenetic changes that may contribute to disease. These are one form of epigenetic changes, known as methylation, measured in small samples of blood collected on cards.
