Two Minute Talk: Mitotic Cell Rounding Hymanlab 2014-07-28 | Describe your project in 2 minutes or less! Hyman lab postdoc Elisabeth Fischer-Friedrich explains the biophysics of why and how cells become round during mitosis. Written and narrated by Elisabeth Fischer-Friedrich. Produced by Lisa Dennison.
A quick intro to the Second Law of Thermodynamics Hymanlab 2022-07-14 | Have you ever seen a tepid cup of coffee getting hot? Or a pile of sand grains organizing themselves into a sand castle? It would be strange, right? But why? The reason is behind one of the most fundamental and general laws of physics: The Second Law of Thermodynamics.
A quick intro to Entropy Hymanlab 2022-07-14 | Entropy is a universal and profound concept that is central to understanding so many systems. From an ink drop mixing in water, to computers, to living beings and even the entire Universe! But what exactly is the entropy of a system? Watch this short video to know more.
Regulation of centrosome assembly by phosphorylation: Wueseke et al, Biology Open 2016 Hymanlab 2016-09-29 | Describe your project in 2 minutes! In this video abstract, Oliver Wueseke tells you about his recent publication in Biology Open, "Polo-like kinase phosphorylation determines C.elegans centrosome size and density by biasing SPD-5 toward an assembly-competent conformation," Learn more in the full paper Wueseke et al. (2016) http://dx.doi.org/10.1242/bio.020990Written and narrated by Oliver Wueseke, illustrated by Jeff Woodruff, edited and produced by Lisa Dennison.
Phase separation in cell polarity: Video abstract for Saha et al, Cell 2016 Hymanlab 2016-09-15 | Describe your project in 2 minutes! In this video abstract, Shamba Saha tells you about his recent publication in Cell, "Polar Positioning of Phase-Separated Liquid Compartments in Cells Regulated by an mRNA Competition Mechanism." Learn more in the full paper Saha et al. (2016) published in Cell, http://dx.doi.org/10.1016/j.cell.2016.08.006Written and narrated by Shamba Saha. Edited and produced by Lisa Dennison.
Two Minute Talk - Video Abstract for Leaver et al, Biology Open 2016. Hymanlab 2016-07-14 | Describe your project in 2 minutes or less! In this video abstract, Mark Leaver tells you about his recent publication in Biology Open, "A locus in Pristionchus pacificus responsible for the ability to give rise to fertile offspring at higher temperatures." Learn more in the full paper Leaver et al. (2016) published in Biology Open, dx.doi.org/10.1242/bio.018127 Written and narrated by Mark Leaver. Edited and produced by Lisa Dennison.Watch Mark's first Two Minute Talk to hear about another approach to this question (http://youtu.be/DFVKpvOUHEg), and watch Maria Begasse's Two Minute Talk to hear about related work in other nematode species (youtu.be/wde9j1cdsYU).
Biscuit, the Group Leader Hymanlab 2016-01-13 | Here's a short, funny clip that was filmed as part of a movie for the birthday celebration and symposium of MPI-CBG Director Eli Knust. If only Eli had let Tony make Biscuit a new group leader!
Two Minute Talk - Video Abstract for Temperature dependence of cell division timing Hymanlab 2015-03-03 | Describe your project in 2 minutes or less! In our lab's first video abstract, Maria Begasse tells you about her recent publication in Cell Reports, "Temperature dependence of cell division timing accounts for a shift in the thermal limits of C. elegans and C.briggsae." Learn more and find a link to the full paper at http://hymanlab.mpi-cbg.de/hyman_lab/temperature/Written and narrated by Maria Begasse. Edited and produced by Lisa Dennison.Watch Mark Leaver's Two Minute Talk to find out the ongoing follow-up work to this publication. http://youtu.be/DFVKpvOUHEg
Two Minute Talk: The Effect of Temperature on Nematodes Hymanlab 2015-02-12 | Describe your project in 2 minutes or less! Hyman lab postdoc Mark Leaver explains how he studies the adaptation of nematodes (round worms) to habitats of different temperatures. Learn more at http://hymanlab.mpi-cbg.de/hyman_lab/temperature/Written and narrated by Mark Leaver. Edited and produced by Lisa Dennison.
What is the Future of Scientific Publishing and Evaluation? Hymanlab 2014-12-18 | Highlights from a panel discussion held at the MPI-CBG on Nov 18, 2014. The discussion featured Jennifer McLennan, head of marketing and communications at the journal eLife, and three MPI scientists at different stages of their careers: Felipe Mora-Bermúdez (senior postdoctoral fellow), Simon Alberti (junior Group Leader), and Tony Hyman (senior Group Leader and MPI Director).Publications are our primary scientific currency and play a major role in how we are evaluated when applying for jobs, tenure, and funding. Thus, the editorial, peer-review, and communication practices of major journals are important for all of us and can affect the progress of our careers, as well as the progress of science.However, publishing has gotten out of control, with scientists valuing journal brand names over real discovery, and with hiring and funding committees relying on Journal Impact Factors to evaluate individual scientists. In addition, scientists are now spending more time than ever on the review process, slowing down the pace of science and especially affecting young scientists who need publications to advance. Has this gone too far? How are we going to tackle these critical problem, and what’s being done already?Read a summary of the discussion here: dresdenpostdocs.wordpress.com/2014/12/18/future-of-publishing-and-evaluation
Tony the arm wrestler Hymanlab 2014-10-15 | Check out Tony as an arm wrestling champ! This clip was part of the fun movie made by Dresden predoc students for PhD selection week in September 2014.
Tony Hyman - What is a Discovery? Hymanlab 2014-09-19 | Tony spoke as part of a summer seminar series hosted by MPI-CBG postdocs during which group leaders gave thoughtful and personal advice about how to start your own group. Tony focused on the main goal of starting your own group -- to discover something important -- and how to stay on track towards achieving that goal.
Two Minute Talk: Phase Transitions in Cells Hymanlab 2014-06-11 | Describe your project in 2 minutes or less! Hyman lab postdoc Louise Jawerth tackles the phase transitions that occur within the cytoplasm. Written and narrated by Louise Jawerth. Produced by Lisa Dennison.
Two Minute Talk: Centrosome Assembly Hymanlab 2014-06-11 | Describe your project in 2 minutes or less! Hyman lab postdoc Jeff Woodruff describes the great unknowns of centrosome assembly and his plan of attack.Written and narrated by Jeff Woodruff. Produced by Lisa Dennison.
XMAP215 Molecules Tip Track on Growing Microtubule Ends Hymanlab 2014-03-11 | XMAP215 molecules (green) are observed as distinct foci at the microtubule plus-end. These foci grow from the ends of the microtubules with an outward velocity that correlates with the previously measured microtubule growth rates for the given concentration of XMAP215 and tubulin. Therefore, we conclude that these foci represent XMAP215-GFP molecules at the growing end of the microtubules, indicating that XMAP215 molecules "tip track" with the plus end of microtubules. Brouhard et al, Cell 2008.
XMAP215 Induced Microtubule Polymerization Hymanlab 2014-03-11 | This is a movie of a seed microtubule (red) with a dynamic microtubule lattice growing from the plus end (green) in the presence of 100 nM XMAP215. Brouhard et al, Cell 2008.
Tony Hyman introduces Tim Mitchison for the 2013 Keith Porter Lecture at ASCB Hymanlab 2014-02-03 | As an old friend and former postdoc of Tim Mitchison, Tony was the perfect person to give the introduction when Tim was invited to give the Keith Porter Lecture at the 2013 ASCB (American Society for Cell Biology) meeting in New Orleans. Watch Tony's fond, laudatory, and often hilarious introduction of Tim, above.
Autranomics in Action Hymanlab 2014-01-31 | An automated system for the systematic cultivation and handling of cells was developed in a collaboration between the Max Planck Society and the Fraunhofer Institute. This cell culture "robot" accomplishes high-throughput cell maintenance, expansion of cell lines, selection of GFP-positive cells, and more, all while being controlled from a remote location. Watch the "robot" in action!
Embryonic development of C. elegans Hymanlab 2013-08-20 | Development of a C. elegans embryo from the first cell division until hatching.The movie was acquired at a temperature of 20C using DIC optics. Credits: Martin Dressler
Scientists Behind The Scenes Hymanlab 2013-07-16 | Featuring Tony and Andres from the Hyman lab!Take a peek into the lives of a few of our favorite MPI-CBG scientists, in and out of the lab. Watch them rock climb in the gym, rock out on stage, and rock a western blot in lab. See them spin a pottery wheel one minute and a centrifuge the next. Find out what it takes to be a scientist (hint: curiosity is the key!). As seen in "Wissenschaft durchs Schlüsselloch" (Science through the Keyhole) at the 11th Annual Dresdener Lange Nacht der Wissenschaften (Long Night of Science).
A Day in the Life of the Hyman Lab Hymanlab 2013-07-16 | As seen in "Wissenschaft durchs Schlüsselloch" (Science through the Keyhole) at the 11th Annual Dresdener Lange Nacht der Wissenschaften (Long Night of Science).
Cortical Flow Hymanlab 2012-09-11 | Dynamic rearrangement of the contractile actomyosin cortical cytoskeleton during polarity establishment in the one-cell C. elegans embryo as visualized with a green fluorescent protein fusion to non-muscle myosin 2 (NMY-2). Flow of this cytoskeletal network towards the anterior (left) of the embryo is thought to be the dominant symmetry-breaking event in the early embryo that specifics the anterior-posterior axis.Movie by: Nathan W. Goehring
Interview with Hyman Lab summer student Hélène Vignes Hymanlab 2012-08-16 | Hélène briefly talks about her summer experience in the Hyman Lab at Max Planck Institute of Molecular Biology & Genetics.
MAN-1 YFP, (focal plane (top) and max-intensity Z-projection (bottom)) Hymanlab 2012-01-10 | Nuclear ProteinsVincent Galy
Laminin YFP, (focal plane (top) and max-intensity Z-projection (bottom)) Hymanlab 2012-01-10 | Nuclear ProteinsVincent Galy
Tubulin GFP Hymanlab 2012-01-10 | Epifluorescence movies of centrosomal and cytoskeleton-associated proteins
Tubulin and Histone GFP Hymanlab 2012-01-10 | Epifluorescence movies of centrosomal and cytoskeleton-associated proteins
TBG-1 GFP Hymanlab 2012-01-10 | Epifluorescence movies of centrosomal and cytoskeleton-associated proteinsAnne-Lore Schlaitz
RSA-1 GFP Hymanlab 2012-01-10 | Epifluorescence movies of centrosomal and cytoskeleton-associated proteinsAnne-Lore Schlaitz
EB1 Hymanlab 2012-01-10 | Epifluorescence movies of centrosomal and cytoskeleton-associated proteinsMartin Srayko
EB1 and Microtubules Hymanlab 2012-01-10 | Epifluorescence movies of centrosomal and cytoskeleton-associated proteinsMartin Srayko
PAR-6 GFP Hymanlab 2012-01-10 | Epifluorescence movies of polarity-related proteins tagged with fluorescent proteinsCarrie R. Cowan
PAR-2 GFP/SPD-2 GFP Hymanlab 2012-01-10 | Epifluorescence movies of polarity-related proteins tagged with fluorescent proteinsCarrie R. Cowan
PAR-2 GFP/(gamme) tubulin GFP/Histone 2B GFP Hymanlab 2012-01-10 | Epifluorescence movies of polarity-related proteins tagged with fluorescent proteinsCarrie R. Cowan
PAR-2 GFP Hymanlab 2012-01-10 | Epifluorescence movies of polarity-related proteins tagged with fluorescent proteinsCarrie R. Cowan
Cyclin E GFP Hymanlab 2012-01-10 | Epifluorescence movies of polarity-related proteins tagged with fluorescent proteinsCarrie R. Cowan
CDK2 TFP Hymanlab 2012-01-10 | Epifluorescence movies of polarity-related proteins tagged with fluorescent proteinsCarrie R. Cowan
PAR-6m Cherry/PAR-2 GFP double line Hymanlab 2012-01-10 | Confocal movies of polarity-related proteins tagged with fluorescent proteins Carsten Höge
NPP-11 GFP Hymanlab 2012-01-10 | Confocal movies of polarity-related proteins tagged with fluorescent proteins Garrett Greenan
PAR-2 GFP through to the Z2 Z3 stage Hymanlab 2012-01-10 | Confocal movies of polarity-related proteins tagged with fluorescent proteinsCarsten Höge
Wild Type (N2) spindle set-up and rocking Hymanlab 2012-01-10 | First embryonic cell division: viewed by time-lapse DIC microscopyPierre Gönczy
Wild Type (N2) Hymanlab 2012-01-10 | First embryonic cell division: viewed by time-lapse DIC microscopyPierre Gönczy
Cytokinesis Mutant (strain t1568) Hymanlab 2012-01-10 | First embryonic cell division: viewed by time-lapse DIC microscopyPierre Gönczy
Chromosome Segregation Mutant (strain t1712) Hymanlab 2012-01-10 | First embryonic cell division: viewed by time-lapse DIC microscopyPierre Gönczy
Spindle Assembly Mutant (strain t1595) Hymanlab 2012-01-10 | First embryonic cell division: viewed by time-lapse DIC microscopyPierre Gönczy
Centrosome Rotation Mutant (strain t1599) Hymanlab 2012-01-10 | First embryonic cell division: viewed by time-lapse DIC microscopyPierre Gönczy
Anaphase Spindle Positioning Hymanlab 2012-01-10 | First embryonic cell division: viewed by time-lapse DIC microscopyPierre Gönczy
