National Library of MedicineThis film describes and demonstrates a prefrontal lobotomy, an operative procedure employed in mental disorders resistive to other methods of treatment. The procedure consists of cutting the white matter in each frontal lobe in the plane of the coronal suture. This passes just anterior to the frontal horn of the ventricle and interrupts the anterior thalamic radiation. This film includes a written description of the procedure, review of landmarks on the skull and frontal lobe on a demonstration skull and brain, operation on a live patient, and X-rays taken after the operation. Filmed with cooperation of George Washington University.
Prefrontal Lobotomy in the Treatment of Mental Disorders (GWU, 1942)National Library of Medicine2018-07-24 | This film describes and demonstrates a prefrontal lobotomy, an operative procedure employed in mental disorders resistive to other methods of treatment. The procedure consists of cutting the white matter in each frontal lobe in the plane of the coronal suture. This passes just anterior to the frontal horn of the ventricle and interrupts the anterior thalamic radiation. This film includes a written description of the procedure, review of landmarks on the skull and frontal lobe on a demonstration skull and brain, operation on a live patient, and X-rays taken after the operation. Filmed with cooperation of George Washington University.
Learn more about the National Library of Medicine's historical audiovisuals program at: nlm.nih.gov/hmd/collections/filmsChanging the Face of Medicine | Dr. Vivian PinnNational Library of Medicine2024-10-18 | Dr. Vivian Pinn served as the first full-time director of the Office of Research on Women’s Health (ORWH) at the National Institutes of Health (NIH). Additionally, she was the first African American woman to chair an academic pathology department in the United States, at Howard University College of Medicine.
She’s featured in Changing the Face of Medicine: Celebrating America’s Women Physicians, an online exhibition from the National Library of Medicine. Visit the homepage to see more: nlm.nih.gov/exhibition/changing-the-face-of-medicine/index.html. #humanhealth #medicalhistory #womeninmedicineChanging the Face of Medicine | Dr. Ann PrestonNational Library of Medicine2024-10-18 | Dr. Ann Preston was the first woman dean of the Woman's Medical College of Pennsylvania and advocated for women students to receive medical education.
She’s featured in Changing the Face of Medicine: Celebrating America’s Women Physicians, an online exhibition from the National Library of Medicine. Visit the homepage to see more: nlm.nih.gov/exhibition/changing-the-face-of-medicine/index.html. #humanhealth #medicalhistory #womeninmedicineChanging the Face of Medicine | Dr. Audrey Forbes ManleyNational Library of Medicine2024-10-18 | Dr. Audrey Forbes Manley was the first African American woman to achieve the rank of assistant surgeon general (Rear Admiral in the Public Health Service.)
She’s featured in Changing the Face of Medicine: Celebrating America’s Women Physicians, an online exhibition from the National Library of Medicine. Visit the homepage to see more: nlm.nih.gov/exhibition/changing-the-face-of-medicine/index.html. #humanhealth #medicalhistory #womeninmedicineChanging the Face of Medicine | Dr. Louise PearceNational Library of Medicine2024-10-18 | Dr. Louise Pearce’s research helped lead to a cure for trypanosomiasis (African sleeping sickness) in 1919.
She’s featured in Changing the Face of Medicine: Celebrating America’s Women Physicians, an online exhibition from the National Library of Medicine. Visit the homepage to see more: nlm.nih.gov/exhibition/changing-the-face-of-medicine/index.html. #humanhealth #medicalhistory #womeninmedicineChanging the Face of Medicine | Dr. JoAnn Elisabeth MansonNational Library of Medicine2024-10-18 | Dr. JoAnn Elisabeth Manson is a leading researcher in women’s health and public health.
She’s featured in Changing the Face of Medicine: Celebrating America’s Women Physicians, an online exhibition from the National Library of Medicine. Visit the homepage to see more: nlm.nih.gov/exhibition/changing-the-face-of-medicine/index.html. #humanhealth #medicalhistory #womeninmedicineChanging the Face of Medicine | Dr. Edithe J. LevitNational Library of Medicine2024-10-18 | Dr. Edithe J. Levit established new ways to evaluate doctors’ clinical competence and was the first woman president of a national medical association, the National Board of Medical Examiners.
She’s featured in Changing the Face of Medicine: Celebrating America’s Women Physicians, an online exhibition from the National Library of Medicine. Visit the homepage to see more: nlm.nih.gov/exhibition/changing-the-face-of-medicine/index.html. #humanhealth #medicalhistory #womeninmedicineChanging the Face of Medicine | Dr. Fernande Marie PelletierNational Library of Medicine2024-10-18 | Dr. Fernande Pelletier works as a Medical Mission Sister to deliver health care to underserved communities in Ghana.
She’s featured in Changing the Face of Medicine: Celebrating America’s Women Physicians, an online exhibition from the National Library of Medicine. Visit the homepage to see more: nlm.nih.gov/exhibition/changing-the-face-of-medicine/index.html. #humanhealth #medicalhistory #womeninmedicineChanging the Face of Medicine | Dr. Joan Y. ReedeNational Library of Medicine2024-10-18 | Dr. Joan Y. Reede was appointed Harvard Medical School’s first dean for diversity and community partnership and has worked to bring more minority students into the health professions.
She’s featured in Changing the Face of Medicine: Celebrating America’s Women Physicians, an online exhibition from the National Library of Medicine. Visit the homepage to see more: nlm.nih.gov/exhibition/changing-the-face-of-medicine/index.html. #humanhealth #medicalhistory #womeninmedicineChanging the Face of Medicine | Dr. Helen M. RanneyNational Library of Medicine2024-10-18 | Dr. Helen M. Ranney made pivotal contributions to sickle cell anemia research and became the first woman president of the Association of American Physicians.
She’s featured in Changing the Face of Medicine: Celebrating America’s Women Physicians, an online exhibition from the National Library of Medicine. Visit the homepage to see more: nlm.nih.gov/exhibition/changing-the-face-of-medicine/index.html. #humanhealth #medicalhistory #womeninmedicineChanging the Face of Medicine | Dr. Helen Rodriguez-TriasNational Library of Medicine2024-10-18 | Dr. Helen Rodriguez-Trias worked to improve access to health services for women and children in underserved communities, advocated for women’s rights, and served as the first Latina president of the American Public Health Association.
She’s featured in Changing the Face of Medicine: Celebrating America’s Women Physicians, an online exhibition from the National Library of Medicine. Visit the homepage to see more: nlm.nih.gov/exhibition/changing-the-face-of-medicine/index.html. #humanhealth #medicalhistory #womeninmedicineChanging the Face of Medicine | Dr. Esther M. SternbergNational Library of Medicine2024-10-18 | Dr. Esther Sternberg is internationally recognized for her groundbreaking work on the mind-body connection in illness and healing.
She’s featured in Changing the Face of Medicine: Celebrating America’s Women Physicians, an online exhibition from the National Library of Medicine. Visit the homepage to see more: nlm.nih.gov/exhibition/changing-the-face-of-medicine/index.html. #humanhealth #medicalhistory #womeninmedicineChanging the Face of Medicine | Dr. Janet Davison RowleyNational Library of Medicine2024-10-18 | Dr. Janet Davison Rowley identified the translocation of chromosomes as the cause of leukemia and other cancers.
She’s featured in Changing the Face of Medicine: Celebrating America’s Women Physicians, an online exhibition from the National Library of Medicine. Visit the homepage to see more: nlm.nih.gov/exhibition/changing-the-face-of-medicine/index.html. #humanhealth #medicalhistory #womeninmedicineChanging the Face of Medicine | Dr. Nancy L. SnydermanNational Library of Medicine2024-10-18 | Dr. Nancy Snyderman had a decades’ long career in broadcast medical journalism, serving as a correspondent for ABC television's Good Morning America for 15 years.
She’s featured in Changing the Face of Medicine: Celebrating America’s Women Physicians, an online exhibition from the National Library of Medicine. Visit the homepage to see more: nlm.nih.gov/exhibition/changing-the-face-of-medicine/index.html. #humanhealth #medicalhistory #womeninmedicineChanging the Face of Medicine | Dr. Anna Wessels WilliamsNational Library of Medicine2024-10-18 | Dr. Anna Wessels Williams isolated a strain of bacteria that scientists used to develop the treatment for diphtheria.
She’s featured in Changing the Face of Medicine: Celebrating America’s Women Physicians, an online exhibition from the National Library of Medicine. Visit the homepage to see more: nlm.nih.gov/exhibition/changing-the-face-of-medicine/index.html. #humanhealth #medicalhistory #womeninmedicineChanging the Face of Medicine | Dr. Leah J. DicksteinNational Library of Medicine2024-10-18 | Dr. Leah J. Dickstein developed a program to help medical students balance their studies and family lives and was president of the American Medical Women’s Association.
She’s featured in Changing the Face of Medicine: Celebrating America’s Women Physicians, an online exhibition from the National Library of Medicine. Visit the homepage to see more: nlm.nih.gov/exhibition/changing-the-face-of-medicine/index.html. #humanhealth #medicalhistory #womeninmedicineVisionary Technology: Exploring Eyeglasses and Impairment in the NLM’s CollectionsNational Library of Medicine2024-10-18 | Rachael Gillibrand, PhD — University of Leeds
2:00 p.m. – 3:00 p.m. ET — This talk will be live-streamed globally, and archived on NLM's YouTube Channel and NIH VideoCasting.
Join Dr. Rachael Gillibrand as she explores the connections between eye impairments and the creation of eyeglasses, using the collections of the National Library of Medicine (NLM). The talk will highlight items from her 'ocular impairment' resource collection, accessible through the Medical Heritage Library, as well as materials used in her forthcoming book on premodern disability. Together, we will dive into the pages of historical texts, including Guy de Chauliac's Chyrurgia, Bartholomeus Anglicus' De proprietatibus rerum and the writings of Ambroise Paré, to explore how ocular health has influenced the design of eyeglasses throughout history.NLM Invests in AI (2024)National Library of Medicine2024-10-16 | NLM is a Partner in an AI-Empowered Health Care System #ai #machinelearning #libraryChanging the Face of Medicine: Celebrating America’s Women PhysiciansNational Library of Medicine2024-10-16 | Changing the Face of Medicine: Celebrating America’s Women Physicians is an online exhibition from the National Library of Medicine. Visit the homepage to see more: nlm.nih.gov/exhibition/changing-the-face-of-medicine/index.html #humanhealth #medicalhistory #womeninmedicineChanging the Face of Medicine | Dr. Mary Ellen AveryNational Library of Medicine2024-10-16 | Dr. Mary Ellen Avery helped discover the cause of respiratory distress syndrome (RDS) in premature babies. Additionally, she trained and advocated for young physicians in a long career in academic medicine.
She’s featured in Changing the Face of Medicine: Celebrating America’s Women Physicians, an online exhibition from the National Library of Medicine. Visit the homepage to see more: nlm.nih.gov/exhibition/changing-the-face-of-medicine/index.html. #humanhealth #medicalhistory #womeninmedicineChanging the Face of Medicine | Dr. Barbara BarlowNational Library of Medicine2024-10-16 | Dr. Barbara Barlow founded the Injury Free Coalition for Kids and helped increase public education on how to prevent childhood injuries.
She’s featured in Changing the Face of Medicine: Celebrating America’s Women Physicians, an online exhibition from the National Library of Medicine. Visit the homepage to see more: nlm.nih.gov/exhibition/changing-the-face-of-medicine/index.html. #humanhealth #medicalhistory #womeninmedicineChanging the Face of Medicine | Dr. Emily Dunning BarringerNational Library of Medicine2024-10-16 | Dr. Emily Dunning Barringer became the first woman medical resident and ambulance physician in New York. She also lobbied Congress to allow women physicians to receive commissions in the Armed Forces and the Public Health Service.
She’s featured in Changing the Face of Medicine: Celebrating America’s Women Physicians, an online exhibition from the National Library of Medicine. Visit the homepage to see more: nlm.nih.gov/exhibition/changing-the-face-of-medicine/index.html. #humanhealth #medicalhistory #womeninmedicineChanging the Face of Medicine | Dr. Leona BaumgartnerNational Library of Medicine2024-10-16 | Dr. Leona Baumgartner was the first woman to become commissioner of the New York City Department of Health and pioneered health education programs and health services in poor communities.
She’s featured in Changing the Face of Medicine: Celebrating America’s Women Physicians, an online exhibition from the National Library of Medicine. Visit the homepage to see more: nlm.nih.gov/exhibition/changing-the-face-of-medicine/index.html. #humanhealth #medicalhistory #womeninmedicineChanging the Face of Medicine | Dr. Marie E. ZakrzewskaNational Library of Medicine2024-10-16 | Dr. Marie Zakrzewska founded the New England Hospital for Women and Children, the second hospital in the United States to be run by women physicians and surgeons.
She’s featured in Changing the Face of Medicine: Celebrating America’s Women Physicians, an online exhibition from the National Library of Medicine. Visit the homepage to see more: nlm.nih.gov/exhibition/changing-the-face-of-medicine/index.html. #humanhealth #medicalhistory #womeninmedicineChanging the Face of Medicine | Dr. Barbara Ross-LeeNational Library of Medicine2024-10-16 | Dr. Barbara Ross-Lee was the first African American woman to be appointed dean of a U.S. medical school.
She’s featured in Changing the Face of Medicine: Celebrating America’s Women Physicians, an online exhibition from the National Library of Medicine. Visit the homepage to see more: nlm.nih.gov/exhibition/changing-the-face-of-medicine/index.html. #humanhealth #medicalhistory #womeninmedicineChanging the Face of Medicine | Dr. Jane Cooke WrightNational Library of Medicine2024-10-16 | Dr. Jane Cooke Wright advanced chemotherapy techniques through her pioneering cancer research.
She’s featured in Changing the Face of Medicine: Celebrating America’s Women Physicians, an online exhibition from the National Library of Medicine. Visit the homepage to see more: nlm.nih.gov/exhibition/changing-the-face-of-medicine/index.html. #humanhealth #medicalhistory #womeninmedicineChanging the Face of Medicine | Dr. Paula L. StillmanNational Library of Medicine2024-10-16 | Dr. Paula L. Stillman developed a tool that is used to evaluate the clinical competence of medical students, foreign medical graduates, and U.S. doctors in danger of losing their licenses.
She’s featured in Changing the Face of Medicine: Celebrating America’s Women Physicians, an online exhibition from the National Library of Medicine. Visit the homepage to see more: nlm.nih.gov/exhibition/changing-the-face-of-medicine/index.html. #humanhealth #medicalhistory #womeninmedicineChanging the Face of Medicine | Dr. Marianne SchueleinNational Library of Medicine2024-10-16 | Dr. Marianne Schuelein campaigned for childcare tax deductions, which Congress pass into law in 1976, enabling more women to work outside the home.
She’s featured in Changing the Face of Medicine: Celebrating America’s Women Physicians, an online exhibition from the National Library of Medicine. Visit the homepage to see more: nlm.nih.gov/exhibition/changing-the-face-of-medicine/index.html. #humanhealth #medicalhistory #womeninmedicinePubMed Proximity SearchingNational Library of Medicine2024-10-11 | This tutorial demonstrates how to use proximity searching to find terms close to each other in PubMed. Search for multiple terms appearing in any order within a specified distance of one another in the [Title], [Title/Abstract], or affliliation [ad] fields. For more educational materials on PubMed, see PubMed Online Training at nlm.nih.gov/oet/ed/pubmed/.
Transcript: (music)
In this tutorial you will learn how to use proximity searching in PubMed.
Proximity searching allows you to search for terms that are close to each other.
For example, to find variations of a phrase.
Let’s say you are searching for variations of the phrase healthcare rationing.
You might want to find: rationing healthcare, healthcare rationing, rationing of healthcare, or rationing strategies in healthcare.
Proximity searching in PubMed can be used to supplement Medical Subject Heading searches.
In PubMed, you can use proximity searching to search for multiple words appearing in any order within a specified distance of one another in the title field, the title and abstract fields, or the author Affiliation field.
To search for the word “rationing” and the word “healthcare” with no words in between, in the title or abstract fields of the PubMed records, you would type into the search box: “rationing healthcare”[tiab:~0]
Your results include records with: rationing healthcare, and healthcare rationing in the title or abstract.
To search for the word “rationing” and the word “healthcare” with up to one word in between, in the title or abstract fields of PubMed records, you would type into the search box: “rationing healthcare”[tiab:~1]
This would add to your previous search phrases like: rationing of healthcare, and rationing in healthcare.
To search for the word “rationing” and the word “health care” with up to two words in between, in the title or abstract fields of PubMed records, you would use the same syntax but instead of 1, use the number 2.
This would add to your previous search phrases like: rationing strategies in healthcare.
Using our last example as a template, construct a search for the terms congenital and defect with up to one word in between, in the title field of PubMed.
The title field can be searched with the word title in brackets.
Your results will have records with the terms congenital and defect with up to one word in between, in the title field.
Note that Automatic Term Mapping is not applied to the terms when you do a proximity search.
For comprehensive searches on biomedical terms, you will want to combine proximity searching with other techniques to build your query.
For example, while this search retrieves records with the term “congenital heart defect”… …there are more than 30 more specific Medical Subject Headings under Heart Defects, Congenital.
You would need to include the MeSH term, either directly or through Automatic Term Mapping, to include these more specific terms in your search.
Proximity searching is a powerful tool that should be used in combination with other searches of PubMed.
For more about proximity searching in PubMed, see the PubMed User Guide.
For expert assistance with your PubMed searches, contact your local health sciences librarian.NIH’s Common Data Element Repository (2024)National Library of Medicine2024-10-09 | This video is about the National Institutes of Health (NIH) Common Data Element (CDE) Repository, available at cde.nlm.nih.gov/.
Common data elements are a type of health data standard that supports data interoperability, enabling researchers to combine or compare data across multiple studies. CDEs increase statistical power, impact research outcomes, and accelerate discovery. Through the NIH CDE Repository, the National Library of Medicine (NLM) provides access to CDEs from across NIH. Additionally, NIH-Endorsed CDEs have been reviewed and approved by an expert panel, and they meet established criteria. They are designated with a gold ribbon in the Repository. The Repository allows users to search, browse, compare, and export CDEs.
For more health resources, visit NLM at https://nlm.nih.gov.AI Strategies to Address Data Accessibility Challenges in Biomedical ResearchNational Library of Medicine2024-09-30 | An Extramural Program Webinar: Toward Gold Standards in Data Creation - AI Strategies to Address Data Accessibility Challenges in Biomedical Research
#ai #biomedicalresearch #dataaccessHow to Find the Total Number of Studies in ClinicalTrials.govNational Library of Medicine2024-09-26 | Fast Forward from ClinicalTrials.gov is a series of short videos that address common questions on how to accomplish tasks on ClinicalTrials.gov and the related data entry portal, called PRS. In this video, users will learn how to find the total number of studies on ClinicalTrials.gov, which changes daily. clinicaltrials.gov #clinicaltrials #FastForwardfromClinicalTrialsHow to Search for Studies That May Interest YouNational Library of Medicine2024-09-26 | Fast Forward from ClinicalTrials.gov is a series of short videos that address common questions on how to accomplish tasks on ClinicalTrials.gov and the related data entry portal, called PRS. In this video, users will learn how to search for studies of interest using the many filters available in the ClinicalTrials.gov search form, called Focus Your Search. clinicaltrials.gov #clinicaltrials #FastForwardfromClinicalTrialsHow to Learn if a Study May Be Recruiting and Find Contact InformationNational Library of Medicine2024-09-26 | Fast Forward from ClinicalTrials.gov is a series of short videos that address common questions on how to accomplish tasks on ClinicalTrials.gov and the related data entry portal, called PRS. In this video, users will learn if a study may be recruiting participants and how to find the relevant contact information. clinicaltrials.gov #clinicaltrials #FastForwardfromClinicalTrialsPredecir la Retinopatía DiabéticaNational Library of Medicine2024-09-16 | ¿Qué pasaría si alguien con diabetes está quedándose ciego lentamente y no lo sabe? (What if you had somebody who had diabetes and was slowly going blind and they didn't know it?)
La retinopatía diabética es el daño causado por los vasos sanguíneos de la retina por diabetes. Y es la causa número uno de ceguera en adultos en Estados Unidos que trabajan Por fortuna es tratable y aun reversible si se detecta a tiempo. (Diabetic retinopathy is damage caused to the blood vessels of the retina by diabetes. Diabetic retinopathy is also the number one cause of blindness in working-age adults in the United States. But luckily, it is treatable and even reversible if you catch it early enough.)
¿Qué pasaría si alguien con diabetes está quedándose ciego lentamente y no lo sabe?
La retinopatía diabética es el daño causado por los vasos sanguíneos de la retina por diabetes. Y es la causa número uno de ceguera en adultos en Estados Unidos que trabajan Por fortuna es tratable y aun reversible si se detecta a tiempo.
No queremos que ningún americano se quede ciego por diabetes. Pero en el área que rodea Charles Drew, el Área 6 de Planeación de Servicios del Condado de Los Angeles, hay 1.1 millones de personas, y no hay suficientes proveedores de atención de salud para la comunidad.
Observaremos a pacientes que se están quedando ciegos a pesar de tratarlos. Vi la necesidad de tratar la enfermedad antes.
Lo que tratamos de hacer es usar la informática, IA y telesalud para reducir las diferencias y ofrecer más acceso a los pacientes. Propusimos al NLM usar el aprendizaje de los aparatos para saber quiénes estaban en riesgo de retinopatía diabética sin saberlo, creyendo estar bien.
Casi toda la inteligencia artificial se ha enfocado en clasificar imágenes de la retinopatía diabética y proveer un resultado de la enfermedad. Pero lo interesante es que estamos observando datos sin imágenes.
Vemos factores de riesgo establecidos y datos demográficos y de laboratorio que ya clasificamos, y los usamos para desarrollar modelos predecibles de retinopatía diabética y saber quién tendrá mayor riesgo de contraerla. Y así podemos dirigir nuestros limitados recursos hacia pacientes que se pueden beneficiar.
Lo que hicimos fue crear un modo de grupo, no individual.
Y pudimos ver una población de 31 mil pacientes no monitoreados, y aplicar el aprendizaje de aparatos a los datos de los 30 mil.
Encontramos unos 7,500 que consideramos de muy alto riesgo de retinopatía por nuestros modelos. Y los instructores de salud bilingües y asistentes de investigación les explicaron la importancia de venir.
Este software nos permite continuar maximizando la capacidad de encontrar los pacientes que más necesitan vernos.
El NML dice, “hagámoslo”. Observemos esto que tanto impacta a una población no muy atendida, y busquemos los fondos. Fue increíble.
Este proyecto no existiría sin la Biblioteca Nacional de Medicina. Creo que es una increíble validación del tipo de trabajo innovador de nuestra red de seguridad, tan impactante para la mayoría de la población de pacientes de los Estados Unidos.A Brief Guide to Finding and Comparing Ortholog Data at NCBINational Library of Medicine2024-09-11 | This is a detailed tutorial showing how to start with a human protein, find a set of Cetacean orthologs, align the protein sequences, and explore amino acids that are common within cetaceans, but different from those of the human sequence.
NIH Comparative Genomics Resource (CGR): ncbi.nlm.nih.gov/datasets/cgrThe Beginnings of Machine Learning at NLM (Audio Described Version)National Library of Medicine2024-09-03 | The Lister Hill National Center for Biomedical Communications (LHNCBC) celebrated its 50th anniversary in FY2018. Established by an act of Congress in 1968 “as an urgently required facility for the improvement of communications necessary for health, education, research, and practice,” the Center has led and continues to lead a number of significant research and development initiatives in the dissemination of high quality imagery, natural language processing, high-speed access to biomedical information, consumer health and medical informatics, multimedia visualization, data science, and machine learning.
To commemorate this milestone, the Audiovisual Program Development Branch produced a 50th anniversary video and graphical timeline which were presented at the September 2018 Board of Scientific Counselors meeting. The video highlights LHNCBC’s major accomplishments encompassing such significant achievements as Visible Human, ClinicalTrials.gov, UMLS, MARS, Genetics Home Reference, and Profiles in Science. The timeline exhibit, prominently featured in the Lister Hill Center lobby, chronicles the parallel history of communications technologies, the evolution of interoperable communications standards and biomedical initiatives over five decades, from early satellite voice and image research and development to today’s trans-NIH Big Data to Knowledge initiative.
For 50 years, the Directors, Board of Scientific Counselors, and the diverse and talented researchers, developers, and LHNCBC staff have worked together to fulfill the 1965 vision of Senator Lister Hill, “We must develop a communications system so that the miraculous triumphs of modern science can be taken from the laboratory and transmitted to all in need.” The Center continues its work devoted to this mission in support of NLM programs and products, for “all in need.” #humanhealth #medicalhistory #machinelearning #audiodescription #audiodescriptionsThe History of Telemedicine (Audio Described Version)National Library of Medicine2024-09-03 | The Lister Hill National Center for Biomedical Communications (LHNCBC) celebrated its 50th anniversary in FY2018. Established by an act of Congress in 1968 “as an urgently required facility for the improvement of communications necessary for health, education, research, and practice,” the Center has led and continues to lead a number of significant research and development initiatives in the dissemination of high quality imagery, natural language processing, high-speed access to biomedical information, consumer health and medical informatics, multimedia visualization, data science, and machine learning.
To commemorate this milestone, the Audiovisual Program Development Branch produced a 50th anniversary video and graphical timeline which were presented at the September 2018 Board of Scientific Counselors meeting. The video highlights LHNCBC’s major accomplishments encompassing such significant achievements as Visible Human, ClinicalTrials.gov, UMLS, MARS, Genetics Home Reference, and Profiles in Science. The timeline exhibit, prominently featured in the Lister Hill Center lobby, chronicles the parallel history of communications technologies, the evolution of interoperable communications standards and biomedical initiatives over five decades, from early satellite voice and image research and development to today’s trans-NIH Big Data to Knowledge initiative.
For 50 years, the Directors, Board of Scientific Counselors, and the diverse and talented researchers, developers, and LHNCBC staff have worked together to fulfill the 1965 vision of Senator Lister Hill, “We must develop a communications system so that the miraculous triumphs of modern science can be taken from the laboratory and transmitted to all in need.” The Center continues its work devoted to this mission in support of NLM programs and products, for “all in need.” #humanhealth #medicalhistory #telemedicine #audiodescription #audiodescriptionsHow To Submit High-Throughput Sequence Data to GEO, Gene Expression OmnibusNational Library of Medicine2024-08-29 | This tutorial is for those submitting high-throughput sequence data to GEO, the Gene Expression Omnibus. Submission guidelines page: ncbi.nlm.nih.gov/geo/info/seq.html
GEO home page: ncbi.nlm.nih.gov/geoNNLM Discovery | Canary in the Coal Mine (Audio Described Version)National Library of Medicine2024-08-29 | Indiana is known as the crossroads of America. In recent years Indiana has also become the crossroads of multiple deadly epidemics. In 2015 Austin, Indiana was the epicenter of the worst drug fueled HIV outbreak in the history of the United States. Out of a town of 4300 people.
On this episode of the NNLM Discovery podcast, Region 6’s Community Engagement Coordinator, Darlene Kaskie, shares how NNLM is sponsoring a series of talks at public libraries with Dr. William Cooke, a physician and author in rural Austin Indiana. Dr. Cooke wrote a book called Canary in the Coal Mine about being the only doctor in a small town that was hit by twin epidemics of substance abuse and HIV. His story examines the social determinants of health that contribute to poor healthcare and offers hope that communities can come together to make sure that every child born has access and resources and choices that they need to be healthy and prosperous.
NNLM donated hundreds of copies of Dr. Cooke's book to all the libraries that hosted the event. The libraries then distributed the books to community organizations such as faith-based groups, rehab centers, counseling services, and public health departments.
The NNLM is the outreach arm of the National Library of Medicine with the mission to advance the progress of medicine and improve the public health by providing all U.S. health professionals with equal access to biomedical information and improving the public's access to information to enable them to make informed decisions about their health. The seven Health Sciences Libraries function as the Regional Medical Library (RML) for their respective region, with Region 6 consisting of: Illinois, Indiana, Iowa, Michigan, Minnesota, Ohio and Wisconsin. To learn more about Region 6 visit: http://www.nnlm.gov/about/regions/reg....
All of the artwork for this podcast series has been created with a generative AI text-to-image tool! The text prompt for the episode's artwork was " a canary in a coal mine as an abstract painting.” #audiodescription #humanhealth #HIV #education #audiodescriptions(Audio Described) Multiple Sclerosis Falls Insight Track | NLM Funding SpotlightNational Library of Medicine2024-08-26 | This audio-described video is about a study to develop the Multiple Sclerosis Falls Insight Track (MS-FIT) application. It allows MS patients to log falls and near-falls, view their MS-relevant data and intake-survey responses, communicate with their care team, and receive fall-prevention info.
The audio description in this video provides narration that describes onscreen imagery for users with vision limitations. A non-audio-described version is here: youtube.com/watch?v=TUPjOfeWVf0
Learn more about the MS-FIT study here: https://clinicaltrials.ucsf.edu/trial/NCT05837949
Transcript: [Music] [Riley Bove, MD] People with multiple sclerosis, MS, are at higher risk of falls and it can be due from any combination of difficulty with cognitive processing, vision, strength, balance, or maybe rushing because they have to go to the bathroom.
The project that we have submitted to NLM for funding is MS FIT. MS Falls Insight Track.
This is a digital intervention. It was designed by the intended users, so patients, clinicians, and other stakeholders.
And it's designed to improve the reporting around falls and attention to fall prevention.
[Tara Mutukisna] I was diagnosed with MS in 2016. I think it was tripping on the sidewalks and in the road.
It became pretty common and frustrating. As a competitive person, I didn't appreciate not being able to walk straight and not fall.
[Valerie Block, PT] Fear of falling can stop people doing activities. And not doing activities means that they're not out being social.
It can increase depression. It can reduce physical activity which then has a whole slew of different issues.
[Bove] I see a patient every six months and I know that most of the patient's lived experience is outside of that clinical visit.
And for that reason, we needed to build a system that allowed people to collect information about their falls longitudinally in as simple and unobtrusive and patient-friendly way possible.
And ping clinicians, so that we can better intervene when there is a near fall or a fall, and then continue to intervene until all of the sort of fall reduction strategies are in place.
[Mutukisna] The surveys are so straightforward and clear.
So for me, it's just how many falls have you had today or what was the climate that really impacted your walking ability.
[Bove] It's hard for me to see how this process would have been accomplished without funding from the National Library of Medicine because of the time and care that it takes to build things in a way that they're going to succeed with the intended users.
[Mutukisna] I'm just excited that my the doctors of UCSF are allowing me to live my life, not just treat my MS.
#multiplesclerosisawareness #multiplesclerosisfighter #multiplesclerosissociety @ucsf #audiodescription #audiodescriptionsFinding Links and Citations in PubChemNational Library of Medicine2024-08-26 | PubChem is the National Library of Medicine's open chemistry database. This video demonstrates how to locate citations for the data sources that contributed information about the chemical to PubChem. It also shows how to find links to outside sources about the chemical.
To learn more about resources from the National Library of Medicine, go to learn.nlm.nih.gov
Table of Contents: 0:00 - 1:08: Introduction 1:09 - 2:55: Links to Data Sources 2:56 - 4:48: Links to Outside Sources 4:49 - 5:08: PubChem Help PagesFinding Chemical Information in PubChemNational Library of Medicine2024-08-26 | PubChem is the National Library of Medicine's open chemistry database. This video demonstrates how to search PubChem with chemical names and identifiers, molecular formulas, gene symbols, proteins, pathways, taxons, cell lines, and patent numbers.
To learn more about resources from the National Library of Medicine, go to learn.nlm.nih.gov
Table of Contents:
0:00 - 0:28: Introduction 0:29 - 4:10: Chemical Names and Identifiers 4:11 - 4:48: Molecular formula 4:49 - 6:07: Gene Symbols and Proteins 6:08 - 7:13: Pathways 7:14 - 8:11: Taxons 8:12 - 8:46: Cell Lines 8:47 - 9:40: Patent Numbers 9:40 - 9:54: PubChem Help PagesSearching with Structures in PubChemNational Library of Medicine2024-08-26 | PubChem is the National Library of Medicine's open chemistry database. This video demonstrates how to search PubChem with line notations and structure drawings and how to find identical compounds, similar structures, substructures, and superstructures.
To learn more about resources from the National Library of Medicine, go to learn.nlm.nih.gov
Table of Contents: 0:00 - 0:27: Introduction 0:28 - 1:39: Line Notations 1:40 - 6:10: Draw a Structure 6:11 - 7:34: Similar Structures, Substructures, and Superstructures 7:35 - 7:54: PubChem Help PagesPart 2 - Submit Your Data. An Overview of the dbGaP Submission ProcessNational Library of Medicine2024-08-26 | This is the second in a series of three videos that provide an overview of dbGaP's submission process. dbGaP is the NCBI's Database of Genotypes and Phenotypes.
How to Register a Study: sharing.nih.gov/genomic-data-sharing-policy/submitting-genomic-data/how-to-register-and-submit-a-study-in-dbgap"NLM’s Collection on the US Public Health Service Tuskegee Syphilis Study (Audio Described Version)National Library of Medicine2024-08-22 | In 1932, a study on the effects of untreated syphilis on Black men in Alabama took place, and participants’ informed consent was not collected. After news broke about the study in 1972, an ad hoc federal panel was created to investigate the study. The panel investigated whether the study was justified, should be continued, and if current regulations protected the rights of patients. The final report found the study to be ethically unjustified and that participants were not informed about the nature of their disease, given any effective treatment during the study or later once a highly effective treatment was found. In 1972, the study officially ended after advisement from the panel. The investigation and its subsequent findings led to compensation for the victims and changes in research practices. In 1974, the National Research Act that requires voluntary informed consent became law. In 1979, the Belmont Report highlighted that human research should always have respect for persons, beneficence, and justice. The National Bioethics Advisory Commission reports every two years on the adequacy and uniformity of the Federal rules and policies to protect research participants.
In 1973, Dr. R.C. Backus, Executive Secretary of the Tuskegee Syphilis Ad Hoc Advisory Panel, donated to the National Library of Medicine (NLM) photocopies of original correspondence, memoranda, meeting minutes, reports, and scientific articles on the origin, development, and investigation of the US Public Health Service Syphilis Study at Tuskegee. These papers held by NLM constitute a unique historical collection that has informed research led by historians, medical ethicists, and many others across a variety of disciplines. NLM’s stewardship of this collection supports the library’s mission to enable biomedical research, support health care and public health, and promote healthy behavior.
In 1932, the United States Public Health Service began a study of the effects of untreated syphilis on black men in Macon County, Alabama. Participants’ informed consent was not collected.z
“The study initially involved 600 Black men – 399 with syphilis, 201 who did not have the disease. Researchers told the men they were being treated for “bad blood,” a local term used to describe several ailments, including syphilis, anemia, and fatigue. In exchange for taking part in the study, the men received free medical exams, free meals, and burial insurance.
Four decades later, on July 25, 1972, Associated Press reporter Jean Heller broke news about the study, prompting the U.S. Department of Health, Education, and Welfare, to appoint an ad hoc panel to investigate.
In October 1972, the panel advised stopping the study, and a month later the study was ended.
The panel concluded in their final report that the previous research on African Americans with syphilis was “ethically unjustified.”
At the study's conclusion, only 74 of the original 600 men were still alive. 40 of their wives had been infected and 19 of their children were born with congenital Syphilis.
The Advisory Panel’s investigation led to compensation for the victims of the research and new protocols for the ethical treatment of human subjects of research. Voluntary informed consent for research subjects became the new standard, and an explicit requirement for government-funded research.
In 1997, President Clinton issued a formal Presidential Apology for the Tuskegee Syphilis Study.
During its investigation, the panel collected a broad variety of historical documents and other papers. In 1973, a copy of the panel’s working papers was deposited in the National Library of Medicine, NLM, located on the campus of the National Institutes of Health, in Bethesda, Maryland.
Through this research and related public education made possible by the unique collection held by the NLM, as well as the National Archives, we acknowledge the participants in the Tuskegee study and the injustices they and their families suffered. We also acknowledge the work of the Tuskegee Syphilis Study Ad Hoc Advisory Panel to address the unethical actions of the study which ushered in new protections for the rights of patients, and which continue to evolve with new advances in science and medicine.
The NLM collects and preserves collections such as that of the Tuskegee Study Ad Hoc Advisory Panel to improve transparency in research, and to ensure that lessons of the past inform the present and future of biomedical research, health care and public health, and healthy behavior. #tuskegee #audiodescriptionNNLM Discovery | Period Poverty (Audio Described Version)National Library of Medicine2024-08-22 | Why do we expect to find toilet paper and paper towels in a public restroom, but feminine hygiene products are considered optional? Period Poverty is the struggle many low-income women and girls face while trying to afford menstrual products, which contributes to increased economic vulnerability due to absenteeism and health concerns. With a lack of access to menstrual health supplies, 1 in 4 young women miss class and/or work monthly. Menstrual products are not covered by food stamps or WIC (The Special Supplemental Nutrition Program for Women, Infants, and Children).
After watching this video, listen to this week's episode of the NNLM Discovery podcast, Region 6 Communications & Finance Coordinator Miles Dietz-Castel shares the story of Richland County Public Health Director Dr. Julie Chaya’s initiative to combat period poverty in her community of Mansfield, Ohio.
Listen to season 1 of the NNLM Discovery podcast here - nnlm.gov/podcast
The NNLM is the outreach arm of the National Library of Medicine with the mission to advance the progress of medicine and improve the public health by providing all U.S. health professionals with equal access to biomedical information and improving the public's access to information to enable them to make informed decisions about their health. The seven Health Sciences Libraries function as the Regional Medical Library (RML) for their respective region, with Region 6 consisting of: Illinois, Indiana, Iowa, Michigan, Minnesota, Ohio and Wisconsin. To learn more about Region 6 visit: http://www.nnlm.gov/about/regions/reg....
#periodpoverty #menstrualawareness #audiodescription #audiodescriptionsRobustification of Deep Learning for Medical Imaging (Audio Described Version)National Library of Medicine2024-08-22 | Alan McMillan from the University of Wisconsin-Madison and his team are examining how image interpretation can improve noisy data in a project called Can Machines be Trusted? Robustification of Deep Learning for Medical Imaging. Noisy data is information that cannot be understood and interpreted correctly by machines (such as unstructured text). While deep learning approaches (methods that automatically extract high-level features from input data to discern relationships) to image interpretation is gaining acceptance, these algorithms can fail when the images themselves include small errors arising from problems with the image capture or slight movements (e.g., chest excursion in the breathing of the patient). The project team will probe the limits of deep learning when presented with noisy data with the ultimate goal of making the deep learning algorithms more robust for clinical use.
#artificial-intelligence #deeplearning #medical-imaging #ai #audiodescription #audiodescriptionsDrawing Important Medical Conclusions from Datasets (Audio Described Version)National Library of Medicine2024-08-21 | Dr. McDonald, a Senior Investigator at NLM, collaborates in numerous efforts to facilitate industry adoption of standard vocabularies in electronic medical records and public health reporting, as required by meaningful use regulations. He has been working with numerous NIH Institutes to align research terminology with federally mandated clinical terminologies.
#humanhealth #bigdata #medicare #audiodescription #audiodescriptions(Audio Described) LitVar 2.0: A Genomic Variant Search ToolNational Library of Medicine2024-08-21 | This video on LitVar 2.0 has audio description (AD), which describes imagery for individuals with vision limitations. LitVar 2.0 is a web service that allows users to find and retrieve variant-specific information from the biomedical literature. It uses text mining and machine learning to give different forms of the same variant a unique, standardized name. This lets LitVar 2.0 find all matching articles, regardless of the use of a specific name in the query. LitVar 2.0 is freely available to the research community. Launched in 2023, LitVar 2.0 it is an improved version of LitVar, which launched in 2018.
#ai #machinelearning #textmining #biomedical #audiodescription #audiodescriptions #researchNLM Dream Anatomy Exhibition (Audio Described Version)National Library of Medicine2024-08-20 | The interior of our bodies is hidden to us. What happens beneath the skin is mysterious, fearful, amazing. This 2002 installation featured imaginative anatomical books from the National Library of Medicine’s extensive historical collections, along with the work of 20th- and 21st-century artists. The invention of the printing press in the 15th century-and the cascade of print technologies that followed-helped to inspire a new spectacular science of anatomy, and new spectacular visions of the body. Anatomical imagery proliferated, detailed and informative but also whimsical, surreal, beautiful, and grotesque—a dream anatomy that reveals as much about the outer world as it does the inner self.