To Kill a Motor Neuron: Model systems in the lab to understand ALS in the clinic @EverythingALS
To Kill a Motor Neuron: Model systems in the lab to understand ALS in the clinic  @EverythingALS
Uploaded January 2026 | Updated September 2026, 2 weeks ago
Welcome to another compelling episode of #ExpertTalk by EverythingALS.

In this session, we are joined by Dr. Stephen J. Kolb, Director of the ALS and Motor Neuron Disease Multidisciplinary Clinic and Research Program at The Ohio State University Wexner Medical Center, and Professor of Neurology and Biological Chemistry and Pharmacology at Ohio State.

Dr. Kolb shares insights from the front lines of ALS research and clinical care, focusing on how advances in molecular biology and gene therapy are shaping the future of treatment for people living with ALS. Drawing from both his laboratory and clinical experience, he explores how understanding the genetic and cellular mechanisms of motor neuron disease is opening new pathways for targeted therapies.

This talk highlights the evolving role of precision medicine in ALS, the importance of patient-derived models, and the challenges and opportunities involved in translating research discoveries into real-world clinical care.

In this talk, we cover:
• How molecular and genetic research is advancing our understanding of ALS
• The role of patient-derived models in studying motor neuron disease
• Progress and challenges in developing targeted gene therapies
• What it takes to move discoveries from the lab to the clinic
• How clinical trials are shaping the future of ALS treatment

This session offers a powerful look at how science, medicine, and patient-centered research come together to drive innovation and hope in the ALS community.

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To Kill a Motor Neuron: Model systems in the lab to understand ALS in the clinic

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