Uploaded July 2026 | Updated September 2026, 3 weeks ago
Cardiologist Dr. Peter McCullough on mRNA Persistence, Nattokinase, and the Fight Over COVID-19 Treatment
Six years after standing before the US Senate and calling out the pandemic response in real time, Dr. Peter McCullough returns with new evidence on where the spike protein came from, how long it persists in the body after infection or vaccination, and what's being done to break it down. This episode traces the science from a 2015 gain-of-function paper to a patient still showing circulating spike protein 3.6 years after vaccination.
Get Dr. McCullough's free spike protein guide: myfreespikeguide.com
Host Dave Asprey sits down with Dr. Peter McCullough, a physician trained in internal medicine, cardiology, and epidemiology, and one of the most published and most censored voices of the COVID-19 pandemic. He authored the first multi-drug treatment protocol for COVID-19, testified before the US Senate in 2020 and again in 2025, and has published extensively in the peer-reviewed literature on vaccine safety, spike protein biology, and early treatment. His book Courage to Face COVID-19 and his most recent New York Times bestseller, Vaccines, Mythology, Ideology and Reality, examine the history and science behind vaccine policy.
Dave and Dr. McCullough trace the origins of the spike protein back to 2015 and 2016 research papers describing a lab-created, SARS-like coronavirus explicitly labeled "poised for human emergence," and discuss the funding, institutions, and researchers involved. They break down why synthetic mRNA vaccines resist the body's normal RNA breakdown process, what a patient case revealed about spike protein circulating 3.6 years after vaccination, and how nattokinase, a natural enzyme, has shown the ability to break the spike protein down. They also cover the suppression campaigns against ivermectin and hydroxychloroquine, the wartime propaganda origins of terms like "misinformation" and "anti-vaxxer," and what Dr. McCullough says he would do differently if he ran HHS. The conversation closes with new research on cognitive superagers, the small percentage of people who reach 100 with intact memory and health.
You'll Learn:
-Why 2015 and 2016 research papers described a lab-created coronavirus as "poised for human emergence" years before the pandemic
-Why synthetic mRNA in COVID-19 vaccines resists the body's natural RNA breakdown process
-What one patient's case revealed about spike protein still circulating 3.6 years after vaccination
-How nattokinase, a natural enzyme, has been shown to break down the spike protein
-Why the FDA and FTC targeted ivermectin, hydroxychloroquine, and companies selling nasal sprays during the pandemic
-The wartime propaganda origins of terms like "misinformation," "disinformation," and "anti-vaxxer"
-What Dr. McCullough says he would do first if he were running HHS
-What research on cognitive superagers reveals about the small number of people who reach 100 with intact health
Resources:
• Learn More About Dr. McCullough’s Work At: https://www.twc.health/pages/focal-points
• Get My 2026 Clean Nicotine Roadmap | Enroll for free at daveasprey.com/2026-clean-nicotine-roadmap
• Dave Asprey's Latest News | Go to daveasprey.com to join Inside Track today.
Thank you to our sponsors!
- TrueDark | Visit truedark.com and use code DAVEASPREY15 (discount applies to all frames except Aegis)
- ZenBud | Dave’s Nervous System Biohack. Visit zenbud.health and use code DAVE15 at checkout for a discount.
- Qualia | Go to qualialife.com/ASPREY for 50% off, and use code ASPREY for an additional 15% off.
- ENERGYbits | If you want a simpler, smarter way to support your body… this is it. Head to ENERGYbits.com and use code ASPREY for 20% off your order.
Timestamps:
00:00 – Trailer
00:43 – Intro
02:10 – 2020 Public Health Failures
05:07 – Vaccine History & Mythology
07:19 – Vaccine Hesitancy as Disease
13:12 – Masks & Lockdown Absurdity
18:03 – War on Hydroxychloroquine
23:56 – Ivermectin Suppression
28:58 – FTC Misinformation Crackdown
31:18 – Propaganda Terms Explained
39:55 – McCullough's Confidence & Career
43:08 – Spike Protein Origins
57:10 – Nattokinase & Spike Clearance
58:50 – mRNA Persistence in Body
1:11:50 – Fixing the System
1:17:32 – Political Divisiveness
1:22:41 – Secrets to Longevity
Website: daveasprey.com
TikTok: tiktok.com/@daveaspreyofficial
Instagram: instagram.com/dave.asprey
Facebook: facebook.com/Daveaspreyofficial
X: https://x.com/daveasprey
The Human Upgrade Podcast: instagram.com/TheHumanUpgradePodcast
Try TrueDark glasses: truedark.com
Try Danger Coffee: dangercoffee.com/discount/davetube
Try Suppgrade Labs: shopsuppgradelabs.com
Join my Substack: substack.daveasprey.com
Upgrade Labs: upgradelabs.com
40 Years of Zen: 40yearsofzen.com
Cardiologist Dr. Peter McCullough on mRNA Persistence, Nattokinase, and the Fight Over COVID-19 Treatment
Six years after standing before the US Senate and calling out the pandemic response in real time, Dr. Peter McCullough returns with new evidence on where the spike protein came from, how long it persists in the body after infection or vaccination, and what's being done to break it down. This episode traces the science from a 2015 gain-of-function paper to a patient still showing circulating spike protein 3.6 years after vaccination.
Get Dr. McCullough's free spike protein guide: myfreespikeguide.com
Host Dave Asprey sits down with Dr. Peter McCullough, a physician trained in internal medicine, cardiology, and epidemiology, and one of the most published and most censored voices of the COVID-19 pandemic. He authored the first multi-drug treatment protocol for COVID-19, testified before the US Senate in 2020 and again in 2025, and has published extensively in the peer-reviewed literature on vaccine safety, spike protein biology, and early treatment. His book Courage to Face COVID-19 and his most recent New York Times bestseller, Vaccines, Mythology, Ideology and Reality, examine the history and science behind vaccine policy.
Dave and Dr. McCullough trace the origins of the spike protein back to 2015 and 2016 research papers describing a lab-created, SARS-like coronavirus explicitly labeled "poised for human emergence," and discuss the funding, institutions, and researchers involved. They break down why synthetic mRNA vaccines resist the body's normal RNA breakdown process, what a patient case revealed about spike protein circulating 3.6 years after vaccination, and how nattokinase, a natural enzyme, has shown the ability to break the spike protein down. They also cover the suppression campaigns against ivermectin and hydroxychloroquine, the wartime propaganda origins of terms like "misinformation" and "anti-vaxxer," and what Dr. McCullough says he would do differently if he ran HHS. The conversation closes with new research on cognitive superagers, the small percentage of people who reach 100 with intact memory and health.
You'll Learn:
-Why 2015 and 2016 research papers described a lab-created coronavirus as "poised for human emergence" years before the pandemic
-Why synthetic mRNA in COVID-19 vaccines resists the body's natural RNA breakdown process
-What one patient's case revealed about spike protein still circulating 3.6 years after vaccination
-How nattokinase, a natural enzyme, has been shown to break down the spike protein
-Why the FDA and FTC targeted ivermectin, hydroxychloroquine, and companies selling nasal sprays during the pandemic
-The wartime propaganda origins of terms like "misinformation," "disinformation," and "anti-vaxxer"
-What Dr. McCullough says he would do first if he were running HHS
-What research on cognitive superagers reveals about the small number of people who reach 100 with intact health
Resources:
• Learn More About Dr. McCullough’s Work At: https://www.twc.health/pages/focal-points
• Get My 2026 Clean Nicotine Roadmap | Enroll for free at daveasprey.com/2026-clean-nicotine-roadmap
• Dave Asprey's Latest News | Go to daveasprey.com to join Inside Track today.
Thank you to our sponsors!
- TrueDark | Visit truedark.com and use code DAVEASPREY15 (discount applies to all frames except Aegis)
- ZenBud | Dave’s Nervous System Biohack. Visit zenbud.health and use code DAVE15 at checkout for a discount.
- Qualia | Go to qualialife.com/ASPREY for 50% off, and use code ASPREY for an additional 15% off.
- ENERGYbits | If you want a simpler, smarter way to support your body… this is it. Head to ENERGYbits.com and use code ASPREY for 20% off your order.
Timestamps:
00:00 – Trailer
00:43 – Intro
02:10 – 2020 Public Health Failures
05:07 – Vaccine History & Mythology
07:19 – Vaccine Hesitancy as Disease
13:12 – Masks & Lockdown Absurdity
18:03 – War on Hydroxychloroquine
23:56 – Ivermectin Suppression
28:58 – FTC Misinformation Crackdown
31:18 – Propaganda Terms Explained
39:55 – McCullough's Confidence & Career
43:08 – Spike Protein Origins
57:10 – Nattokinase & Spike Clearance
58:50 – mRNA Persistence in Body
1:11:50 – Fixing the System
1:17:32 – Political Divisiveness
1:22:41 – Secrets to Longevity
Website: daveasprey.com
TikTok: tiktok.com/@daveaspreyofficial
Instagram: instagram.com/dave.asprey
Facebook: facebook.com/Daveaspreyofficial
X: https://x.com/daveasprey
The Human Upgrade Podcast: instagram.com/TheHumanUpgradePodcast
Try TrueDark glasses: truedark.com
Try Danger Coffee: dangercoffee.com/discount/davetube
Try Suppgrade Labs: shopsuppgradelabs.com
Join my Substack: substack.daveasprey.com
Upgrade Labs: upgradelabs.com
40 Years of Zen: 40yearsofzen.com
