The Future of Drug Development: Large Quantitative Models SandboxAQ 2026-09-24 | The Future of Drug Development: Large Quantitative Models
AQCat: The Workflow Revolutionizing Catalyst Discovery SandboxAQ 2025-10-03 | Imagine a world with cleaner air, more abundant food, and truly sustainable energy. Achieving this future depends on catalysts, the unsung heroes of countless reactions inside our bodies and across global industries.But here’s the challenge: discovering new catalysts is traditionally a slow, trial-and-error process that can take decades. What if we could predict a catalyst’s properties before ever stepping foot in a lab?In this video, we'll introduce you to AQChemSim and our groundbreaking computational workflow, AQCat. Built on the massive, open-source AQCat25 dataset, our large quantitative models (LQMs) are trained to act like expert chemists, making predictions with remarkable speed and accuracy.Discover how AQChemSim is reshaping the future of chemistry and sustainability — and why it could be the key to solving some of the world’s biggest challenges.Visit our website to learn more and see how we can collaborate: hsandboxaq.com/solutions/aqchemsim
My AQ Journey | Eddie Rodriguez - SandboxAQ SandboxAQ 2025-10-03 | Listen to Eddie Rodriguez, Senior Hardware Engineer at SandboxAQ, discuss how he values continuous learning and makes an impact in his career.Want to learn more? Visit sandboxaq.comWant to get in touch or write the Education team? Email edu@sandboxaq.comCurious about all things AI + Quantum? Visit our Academy at academy.sandboxaq.com
Inside AQFEP: Reinventing Virtual Screening with Machine Learning SandboxAQ 2025-10-01 | In this tech talk, Jordan Crivelli-Decker and Zane Beckwith break down their recent paper published in the Journal of Chemical Theory and Computation. They explore how machine learning can guide Free Energy Perturbation (FEP) methods, making virtual screening more efficient and accurate for structure-based drug discovery.Virtual screening is a cornerstone of modern computational chemistry, but it’s often limited by time and cost. By combining physics-based simulations with AI, Jordan and Zane show how this approach accelerates drug discovery while keeping scientific rigor intact.If you’re curious about the intersection of AI, molecular simulations, and pharmaceutical innovation, this conversation is for you.Chapters:00:24: What Is Virtual Screening?01:13: Limitations of Free Energy Perturbation (FEP)02:27: Introducing AQFEP04:49: How AQFEP Improves Screening09:36: Applying Active Learning to Virtual Screening15:07: Comparing AQFEP with Other Approaches16:23: Takeaway: Hit Rate19:48: Conclusion: AQFEP Method Impact on Virtual ScreeningCheck out the full paper here: pubs.acs.org/doi/pdf/10.1021/acs.jctc.4c00399Want to learn more about what the AQBioSim team is up to now? Visit sandboxaq.com/solutions/aqbiosim
From Stargazing to Saving Hearts: Hailey Trier’s AQtive Mind SandboxAQ 2025-09-23 | Cardiovascular disease has been the #1 cause of death worldwide for decades. What if we could change that?In this video, Hailey shares her inspiring journey: from growing up fascinated by star maps, to discovering neuroscience, to exploring the deep connection between the brain and the heart. Along the way, she dives into how heart rate variability reveals the body’s ability to adapt to stress and why this research could be key to tackling one of humanity’s biggest health challenges.Tune in to hear more about Hailey’s story.Want to learn more about Hailey's work at SandboxAQ? Check out this blog post: sandboxaq.com/post/from-brains-to-hearts-one-scientists-journey-through-synthetic-dataWant to learn more about what the AQMed team is working on? Visit sandboxaq.com/solutions/quantum-sensing.
The Real Impact of AI on the Job Market | Jack Hidary on CNBC SandboxAQ 2025-09-10 | With major companies like Microsoft, Salesforce, and Oracle announcing AI-driven layoffs, fears about job security are rising. A recent World Economic Forum survey suggests 41% of companies plan to reduce their workforce due to AI. But is that the whole story?In this interview, Jack Hidary, CEO of SandboxAQ, breaks down the real impact of artificial intelligence on the global job market. He discusses which sectors, like warehouse fulfillment and customer service, are most at risk, but also shines a light on the industries poised for massive growth.Discover the surprising sectors—from cybersecurity and healthcare to the power grid and materials science—that are already seeing a surge in demand for skilled workers because of AI. Jack also explains the difference between the "first wave" of AI (like ChatGPT) and the emerging "second wave" that will transform the core 80% of our GDP. Whether you're a student, a professional, or just curious about the future, this is a must-watch conversation about the skills you'll need to thrive in the new AI-powered economy.Timestamps:00:00 - Introduction: AI-driven layoffs are on the rise.00:49 - The Jobs at Risk: Which sectors will shrink due to AI and robotics?01:48 - HUGE Growth Area #1: 500,000 open jobs in Cybersecurity right now.02:18 - HUGE Growth Area #2: How AI is transforming Healthcare and Elder Care.04:04 - The Coming Surge: Why AI needs gigawatts of new power, creating jobs in energy.04:53 - The "Bloom is Off the Rose": Moving from the first wave of AI to the second.05:58 - Beyond ChatGPT: How the "Second Wave of AI" will impact major industries.06:20 - Why companies are cautious about adopting Generative AI for critical tasks.Learn more at: www.sandboxaq.com#AI #FutureOfWork #Economy #SandboxAQ
AQtive Guard Protect: Strategic Remediation for Non-Human Identity Security SandboxAQ 2025-08-06 | The future of data security is here. As digital transformation accelerates, so does the risk of data breaches. That's why SandboxAQ has launched Active Guard Protect: a solution that provides full lifecycle security and management for your non-human identities. ActiveGuard Protect secures the full lifecycle of your secrets and stops data breaches before they happen.Try ActiveGuard Protect today - visit aqtiveguard.com/protect.
From Theory to Therapy: Using AI for Brain Cancer | Jack Hidary on Fox SandboxAQ 2025-08-03 | We've trained AI to chat, but can we train it to treat brain cancer?In this Fox Business interview, SandboxAQ CEO Jack Hidary discusses the company's groundbreaking partnership with biotech firm iOncologi to tackle glioblastoma, one of the most aggressive and treatment-resistant brain cancers. By combining biology with quantitative AI, they're pushing the frontiers of drug discovery and combination therapies.Jack also explains why the rest of the S&P 500 must follow the Magnificent Seven's lead in embedding AI into their core business models. Listen in for his bold prediction about AI's role in the U.S. GDP.From energy infrastructure to healthcare innovation, this is a wide-ranging and urgent conversation about the technological future and what’s holding it back.Do you think quantitative AI will succeed where traditional medicine has failed? Let us know why or why not in the comments!Watch the full interview on Fox Business here: foxbusiness.com/video/6376371386112Subscribe for expert insights on AI, quantum, and industry transformation.Learn more about how SandboxAQ is shaping the future: https://www.sandboxaq.com.
Quantum Key Distribution from Space: How SpeQtral is Securing the Future SandboxAQ 2025-07-31 | What does it take to launch a quantum-secure global network from orbit?In this interview, we go to space with SpeQtral, a pioneering startup building quantum communication infrastructure via satellite. Join Chune Yang Lum and Robert Bedington as they share SpeQtral’s origin story, the physics behind satellite-based quantum key distribution (QKD), and how partnerships with companies like Thales and SES are helping scale the quantum internet.Learn how Singapore became a hub for quantum innovation, why space is critical for secure intercontinental communication, and what it would take for a city to join the global quantum network. This conversation dives into the future of cybersecurity, entanglement-based encryption, and the potential of a fully realized quantum internet.Chapters:0:00 – Intro & Welcome0:37 – How Spectral Got Started1:40 – The SpooQy-1 Mission2:42 – Why Space is Needed for Quantum Communication3:12 – Scaling Secure Comms: Satellites vs Fibers3:55 – The Parallel to Classical Comms Evolution4:45 – Why Singapore is a Quantum Innovation Hub6:34 – Who Needs Quantum Security First?8:09 – How the Industry Has Evolved10:00 – Real-World Partnerships with Thales, SES, and Spain11:59 – How Satellite Entanglement Works13:18 – What It Takes for a City to Join14:40 – Spectral’s 5-Year Vision & Scaling Strategy16:09 – Beyond Encryption: The Future of the Quantum InternetHow do you think quantum will reshape the internet in the next decade? Let us know in the comments!Subscribe for expert insights on AI, quantum, and industry transformation.Learn more about how SandboxAQ is shaping the future: https://www.sandboxaq.com.
Reducing Alert Fatigue Through Enrichment SandboxAQ 2025-07-21 | Finding problematic cryptography is not difficult, but fixing it at scale is. AQtive Guard’s enrichment is rooted in our proprietary database that is composed of publicly available repositories and enhanced with in-house SME expertise. Learn more about this feature at aqtiveguard.com/blog/enriched-perspectives-for-enhanced-cryptographic-security-operations
AIs Trillion Dollar Club: Predictions for the Mag 7 | Jack Hidary on CNBC SandboxAQ 2025-07-11 | SandboxAQ CEO Jack Hidary joins CNBC’s Worldwide Exchange to discuss the rapid rise of NVIDIA, crossing the $4 trillion market cap, their partnership with SandboxAQ, and what this signifies for the broader AI landscape. As Amazon and Alphabet compete over investments in AI company Anthropic, Jack discusses what these moves mean for the industry and how quantitative AI will define the next decade.In this interview, Jack covers:-The implications of Big Tech’s multi-billion dollar AI investments-How SandboxAQ's datasets and large quantitative models (LQMs) are making major drug discovery breakthroughs-His prediction for Nvidia's next landmark market cap-How the Mag 7 will compare to the rest of the economy that's lagging in AI adoptionWhat do you think will define the next wave of AI innovation? Share your predictions in the comments below!Subscribe for expert insights on AI, quantum, and industry transformation.Learn more about how SandboxAQ is shaping the future: https://www.sandboxaq.com.
Introducing SAIR: Structurally Augmented Binding Affinity Data at Unprecedented Scale SandboxAQ 2025-07-09 | Join SandboxAQ and NVIDIA for the official launch of SAIR (Structurally Augmented IC50 Repository).SAIR bridges the longstanding gap between molecular structure and drug potency prediction. With over 1 million protein–ligand pairs and 5.2 million cofolded 3D structures, SAIR enables researchers to train next-generation AI models for virtual screening, lead optimization, and more.In this 30-minute webinar, you'll learn:- What SAIR is and how it was built- How NVIDIA's DGX Cloud AI platform achieved results at record pace- Why structure–activity data at this scale is a breakthrough for AI-driven drug discovery- How you can access and apply SAIR in your own work todayGet more info, and access the database now at: sandboxaq.com/sair
AQNav: The Alternative to GPS | Jack Hidary on The Reboot Podcast SandboxAQ 2025-07-02 | In this excerpt from The Reboot podcast, Sonal Rupani talks with SandboxAQ CEO Jack Hidary about the vulnerabilities of GPS and how technology developed by SandboxAQ aims to address them.AQNav is SandboxAQ’s breakthrough dual-use magnetic navigation system for Assured Positioning Navigation and Timing (APNT). Leveraging powerful quantum sensors, proprietary AI algorithms, and Earth’s crustal magnetic field, AQNav delivers an unjammable, all-weather, terrain agnostic, passive technology, APNT solution where GPS signals are unavailable, denied, or spoofed. Learn more at: sandboxaq.com/aqnav#AQNav
Nvidias AI Revolution: Whats Next for Tech? | Jack Hidary, Squawk on the Street SandboxAQ 2025-06-27 | Nvidia just overtook Microsoft (again). But what’s really driving the next wave of AI value?Jack Hidary, CEO of SandboxAQ, joins Squawk on the Street to break down what’s powering Nvidia’s meteoric rise, why AI adoption is stalling in some industries, and how quantum computing is entering the national security conversation.Listen in to hear Jack explain:-Why the next $5T companies may emerge in the next 24 months-SandboxAQ and Nvidia's partnership to accelerate drug discovery-The shift from language models to quantitative models-The looming employment impact of humanoid robots-Quantum computing as both an opportunity and an existential risk-AI's role in defense when GPS and comms go downChapters:0:00 – Opening & Nvidia's Market Cap Surge1:22 – The Limits of LLMs2:12 – SandboxAQ's Collaboration with Nvidia: A New Era of Drug Discovery2:54 – The Rise of Quantitative AI3:34 – Powering AI: Energy Demands and Grid Strategy4:10 – Industry Lag in AI Integration5:09 – AI and the Auto Industry5:47 – AI’s Impact on Employment7:12 – Quantum Computing: Threat and Opportunity8:18 – AI in Defense and GPS-Denied Environments9:22 – Closing: SandboxAQ named one of Time's 2025 Most Influential CompaniesWhat are your thoughts on the future of AI and its impact on our economy and workforce? Share your predictions in the comments below!Subscribe for expert insights on AI, quantum, and industry transformation.Learn more about how SandboxAQ is shaping the future: https://www.sandboxaq.com.
Inside Quside: How Quantum Randomness is the Seatbelt of Digital Security SandboxAQ 2025-06-26 | In this conversation, SandboxAQ’s Fernando Dominguez Pinuaga interviews Carlos Abellan, CEO and founder of Quside: one of the most promising startups at the intersection of quantum technology and enterprise infrastructure.Carlos outlines how Quside’s quantum random number generators (QRNGs) are solving real market needs in cybersecurity, simulations, and high-performance computing by delivering ultra-fast, hardware-based entropy. The discussion highlights how Quside is scaling its product offerings, expanding into new sectors, and positioning itself as a core enabler of secure and efficient digital systems in the post-quantum era.Whether you're tracking emerging quantum investments or evaluating deep tech commercialization strategies, this interview offers key insights into Quside’s roadmap, customer traction, and vision for long-term impact.Chapters:00:00 - Introduction to Quside & Carlos Abellan 0:01:01 - Carlos's Journey into Quantum Physics and Quside's Origin 0:02:54 - Understanding Quantum Random Number Generation (QRNG) 0:03:45 - The Importance of Randomness in Cryptography 0:06:57 - Quside's Product Expansion: Cryptography, Monte Carlo, and Risk Optimization 0:08:13 - The Role of Randomness Processing Units (RPUs) 0:08:59 - Quside's Target Customers and Market Segments 0:10:09 - The "GPT Moment" for Quantum Randomness 0:11:59 - Impact of AI on Security and Randomness Needs 0:13:27 - Quantum Randomness vs. Classical & Quside's Differentiators 0:15:29 - The Value of Secure Randomness 0:16:41 - Vision for the Future & Driving Adoption 0:18:04 - Biggest Challenges and Desired Investors 0:19:06 - Carlos's Closing MessageWhat are your thoughts on the future of digital trust in an AI-driven world? Let us know in the comments!Subscribe for expert insights on AI, quantum, and industry transformation.Learn more about how SandboxAQ is shaping the future: https://www.sandboxaq.com.
AIs Quantitative Future | Wall Street Week Interview with Jack Hidary SandboxAQ 2025-06-24 | In this episode of Bloomberg's Wall Street Week, Jack Hidary, CEO of SandboxAQ, joins David Westin to explore where AI is headed, how Large Quantitative Models (LQMs) will reshape the AI landscape, and what the next paradigm of computing might look like. They dive into the rapid evolution of large language models, the fusion of AI with physics, and how governments and enterprises are preparing for a post-LLM world.From the challenges of error correction to the promise of quantum sensing, this conversation offers an accessible look into technologies that could soon redefine entire industries.Where do you think AI is going after LLMs? Let us know in the comments!Subscribe for expert insights on AI, quantum, and industry transformation.Learn more about how SandboxAQ is shaping the future: https://www.sandboxaq.com.
Unlocking Biological Insights with SandboxAQ’s Knowledge Graph SandboxAQ 2025-06-13 | Discover how SandboxAQ is transforming biomedical research with an advanced knowledge graph powered by agentic AI. This dynamic and continuously updated system synthesizes decades of research into a comprehensive, easily searchable graph architecture with 3D visualizations. Our graph allows you to:-Identify pathways impacted (and not impacted) by your drug-Compare mechanisms of action to competing molecules-Provide tangible evidence for a favorable safety profileYou can even feed your own research into the knowledge graph, and our models will generate new, more accurate hypotheses.Click here to learn more and see how we can collaborate: sandboxaq.com/solutions/aqbiosim
Liquid Time Constant Networks: Precision Navigation without GPS | Tech talk with Favour Nerrise SandboxAQ 2025-06-11 | Imagine flying through hostile airspace and your GPS signal goes dark. What guides you now? In this tech talk, Favour Nerrise, an AI/ML Resident at SandboxAQ and a PhD candidate at Stanford, unveils cutting-edge research on magnetic anomaly navigation (MagNav). Dig into the technical details of how quantum sensors, physics-informed machine learning, and nature-inspired AI models like liquid time-constant networks (LTCs) are creating jam-resistant, precise, and GPS-free navigation systems for aircraft and beyond.Topics include:-Why GPS isn’t always reliable-How quantum sensors unlock new possibilities in navigation-How biology-inspired neural networks help denoise complex signals-Real-world results from the MIT + Air Force magnetic navigation challengeThis is a must-watch for anyone interested in quantum tech, AI, aerospace, or defense innovation.Chapters:00:28 - What is Quantum Sensing?01:25 - Why Traditional GPS Falls Short02:12 - Enter Magnetic Anomaly Navigation (MagNav)03:45 - Why MagNav is Jam-Resistant04:35 - Quantum Sensors for Long-Term, Covert Navigation05:07 - A Brief History of MagNav Research06:28 - The Challenge: Extracting True Signals from Noisy Aircraft Data07:12 - MIT + Air Force Flight Experiment Overview08:32 - Research Question: Modeling Complex Spatiotemporal Dynamics09:01 - Using Reservoir Computing for Navigation AI10:13 - Liquid Time Constant Networks Explained11:23 - Neural Network Architecture Inspired by Worms13:00 - Closed-Form vs ODE-Based Models15:28 - Airborne Magnetic Compensation with LTC Networks16:44 - Sensor Placement & Data Features17:19 - Results: 64% Error Reduction vs Classical Baselines18:14 - Visualizing Predictions vs Ground Truth19:40 - Key Takeaways & Conclusions20:13 - Future Work: Scientific ML, Geophysics, and Unsupervised LearningYou can check out the paper referenced in the video here: arxiv.org/pdf/2401.09631Learn more about all of the other deep tech work happening at SandboxAQ in our publication library:pub.sandboxaq.com
Transformers or RetNets? The Best Model for Quantum Chemistry | Tech Talk with Oliver Knitter SandboxAQ 2025-05-28 | Quantum chemistry simulations are notoriously hard to scale. Could neural networks offer a better path forward? In this tech talk, Dr. Oliver Knitter, an applied mathematician and quantum computing researcher at SandboxAQ, walks through his latest research on neural quantum states (NQS): a deep learning-based method for simulating quantum systems with high accuracy and improved scalability.You’ll learn how classical neural networks like transformers and newer architectures like Retentive Networks (RetNets) can be used as variational ansätze to approximate molecular ground states. Oliver also introduces a technique called Variational Neural Annealing (VNA) that significantly boosts model performance, even for smaller architectures.Whether you're working in machine learning, computational chemistry, or just curious about how AI is accelerating scientific discovery, this tech talk offers a clear and thoughtful breakdown of where the field is heading.Topics include:-Quantum chemistry fundamentals -What neural quantum states (NQS) are and why they matter-Limitations of Transformers and how RetNets offer a scalable alternative-Variational Neural Annealing: a regularization strategy for better accuracy-Implications for AI-driven molecular simulationChapters:0:00 – Introduction: AI Meets Quantum Chemistry1:04 – What Are Neural Quantum States?1:59 – Quantum Chemistry 1012:54 – Electrons and Orbitals: The True Quantum Picture4:16 – The Born-Oppenheimer Approximation5:22 – The Hamiltonian and Energy in Molecules6:00 – Understanding Orbitals and Superposition7:12 – Trial Wavefunctions and Variational Ansatz7:43 – Why Use Neural Networks in Quantum Chemistry?9:08 – Using Monte Carlo Sampling with NQS10:49 – Transformers in Neural Quantum States12:13 – The Scaling Problem with Transformers13:50 – Recurrent Neural Networks (RNNs) Make a Comeback14:13 – What Are Retentive Networks (RetNets)?15:09 – Scaling Analysis: Transformers vs. RetNets17:06 – When Are RetNets More Efficient?19:03 – Introducing Variational Neural Annealing (VNA)21:24 – VNA Boosts Accuracy in Older Models Too21:59 – Accuracy vs. Scalability: Why It Matters22:42 – The Future: Revisiting RNNs in Quantum AI22:59 – Open Source Tools & Closing RemarksYou can check out the paper referenced in the video here:iopscience.iop.org/article/10.1088/2632-2153/adcb88Explore our open-source codebase here: github.com/sandbox-quantum/TangeloLearn more about all of the other deep tech work happening at SandboxAQ in our publication library:pub.sandboxaq.com
The AI Coding Wars: Jack Hidary on CNBC SandboxAQ 2025-05-21 | In this compelling conversation, Jack Hidary, CEO of SandboxAQ and former X (Moonshot) leader at Google, decodes the rapid shifts in AI, quantum computing, and geopolitics. From the rise of coding assistants and large quantitative models (LQMs) to the quantum threats facing Bitcoin and global tech power plays between the U.S., China, and the Gulf states, this interview covers it all.Hidary, also the author of "Quantum Computing: An Applied Approach," gives a unique insider perspective on:-The battle for dominance in developer tools like Codex and Gemini-How LQMs differ from LLMs and what it means for healthcare-The future of quantum computing companies and likely M&A trends-The critical role the Gulf states play in the U.S.–China AI raceWhat do you think is the next battle in the coding wars? Let us know in the comments!Chapters00:00 - Introduction to Jack Hidary & SandboxAQ 00:17 - Google, Gemini & the "Coding Wars" 00:55 - The battle for developer mindshare 01:31 - Gemini vs. ChatGPT in productivity tools 01:54 - Search disruption and the rise of Grok & ChatGPT 02:14 - The three fronts of the AI battle: consumer, prosumer, B2B 02:52 - How SandboxAQ is different: LQMs vs. LLMs 03:39 - Quantum AI and its role in enterprise solutions 03:59 - Who's building quantum computers? A look at the players 04:24 - Public quantum companies and M&A predictions 05:08 - Why hyperscalers may acquire quantum startups 05:32 - Geopolitics of AI: U.S., China, and the Gulf states 06:04 - Strategic partnerships with UAE and others 06:45 - China's AI and quantum investments 07:05 - How quantum computing threatens Bitcoin 07:27 - The need for quantum-safe cryptographySubscribe for expert insights on AI, quantum, and industry transformation.Learn more about how SandboxAQ is shaping the future: https://www.sandboxaq.com.
Why LQMs Will Outshine LLMs | Jack Hidary at RSA 2025 SandboxAQ 2025-05-14 | From RSA Conference 2025, SandboxAQ CEO Jack Hidary shares what Sandbox’s latest strategic investment round signals about the current landscape of artificial intelligence. From cutting-edge applications in cybersecurity to the fusion of quantum tech and AI, the industry is heading towards a quantitative future. Jack reveals how SandboxAQ is leading the charge with Large Quantitative Models (LQMs), reshaping industries from finance to healthcare, far beyond what LLMs can do.Tune in to hear about:-The difference between LQMs and LLMs-How LQMs power breakthroughs in drug discovery and materials science-AQtive Guard: AI-powered cybersecurity from SandboxAQ-Quantum sensors and GPS-independent navigation-Why 80% of global GDP depends on the success of LQMsJoin J.D. Durkin from NYSE as he sits down with Jack for a wide-ranging, high-impact conversation on how AI and quantum are shaping the future.Chapters:00:00 – Intro & Welcome from RSAC 202500:36 – Strategic Investment & Market Momentum02:20 – LQMs vs LLMs: What’s the Difference?04:47 – AI for Cybersecurity: Introducing AQtive Guard07:23 – Quantum Sensors & Navigation Without GPS09:22 – The Future of AQ: AI + Quantum InnovationJack shares a lot of ideas -- what stands out to you most? How do you see AI and quantum shaping your industry? Let us know in the comments below!Curious about how LQMs are shaping the future of AI? Learn more about SandboxAQ’s AI solutions here: sandboxaq.com/solutions/large-quantitative-models
Large Quantitative Models: The Future of Drug Discovery | Nadia Harhen on the Gen AI Podcast SandboxAQ 2025-05-08 | What if AI could help cure diseases like Parkinson’s or Alzheimer’s? Tune in to hear SandboxAQ’s Nadia Harhen, General Manager of AI Simulation, introduce us to Large Quantitative Models (LQMs), a powerful scientific approach that's revolutionizing the field of drug discovery. Nadia explains why traditional drug development is broken, the differences between LQMs and LLMs, and why physics-based AI is the key to faster, more reliable innovation in healthcare.Key highlights:-Why 90% of drugs fail clinical trials-How LQMs simulate real-world chemistry-Real results: LQMs reduce cost and time in biotech R&D-How grounding AI in physics creates reliable, reproducible models-The future of AI in solving the toughest medical challengesChapters00:00 – Intro: What are Large Quantitative Models (LQMs)? 00:49 – Meet Nadia Harhen and her work at SandboxAQ 01:48 – The massive challenges in drug discovery 02:14 – Why AI has yet to disrupt biopharma effectively 03:25 – The problem with relying only on training data 04:20 – What “undruggable” really means 05:30 – Why LLMs fall short in science 06:22 – What makes LQMs different from LLMs 07:29 – How LQMs simulate physics for precision 08:55 – Hallucination vs. scientific accuracy 10:58 – Generative AI and why synthesize-ability matters 11:45 – Combining generative AI with quantum chemistry 12:45 – Results: LQMs outperform traditional methods 13:45 – Fighting Parkinson’s with the Michael J. Fox Foundation 15:35 – How LQMs cut costs and time in clinical R&D 16:58 – Ethics, reproducibility, and reliability of LQMs 18:30 – Trust and transparency in AI-powered science 20:00 – New molecules and smarter discovery 21:32 – LQMs as a competitive edge for biotechs 22:26 – A look ahead: LQMs shaping the future of healthcare 24:00 – Call to action: Learn more and get involvedCurious about how AI and LQMs are shaping the future of biomedicine? Learn more about SandboxAQ’s AI solutions here: sandboxaq.com/solutions/large-quantitative-models
Interview with Michele Mosca: How evolutionQ Is Protecting Against the Quantum Threat SandboxAQ 2025-05-06 | The threat of quantum computing is looming over today’s data encryption. In this interview, SandboxAQ’s VP of Global Outreach, Fernando Dominguez Pinuaga, sits down with Michele Mosca, co-founder of EvolutionQ and one of the pioneers of quantum-safe cryptography, to discuss how we prepare for a post-quantum world.Michele shares insights from decades of work at the intersection of quantum computing, cybersecurity, and policy, explains what cryptographic resilience really means, and reveals how his company, EvolutionQ, is helping governments and Fortune 500s stay ahead of the quantum curve.Tune in to hear about: -The real threat quantum computers pose to today’s encryption -How expert opinion has shifted in the Quantum Threat Survey -Why cryptographic diversity and defense-in-depth are critical now -EvolutionQ’s global work with governments, banks, and space agencies -What leaders can do today to prepare for tomorrow’s threatsIf you’re a CIO, policymaker, or investor, you won't want to miss this special interview with one of the founders of quantum security!Chapters:00:00 – Intro: Meet Michele Mosca & evolutionQ01:00 – Why Move from Academia to Cybersecurity Startup02:20 – How evolutionQ Helps Organizations Build Quantum Resilience03:15 – The Quantum Threat Survey: What the Experts Say05:00 – Rising Risk: Why 20–30% Likelihood Is a Red Flag06:00 – Real-World Adoption: Banks, Governments & Regulators07:45 – What Cryptographic Resilience Really Means09:00 – How evolutionQ’s Tech Works in Simple Terms11:00 – Public vs. Symmetric Key Cryptography Explained12:45 – The Quantum Threat Is Real—But We’re Not Helpless14:00 – Advice for CEOs, CISOs & Policymakers16:00 – Why We Can’t Afford to Wait16:40 – The ESA Project: Connecting Cities with Quantum-Safe Networks18:00 – How evolutionQ Complements Existing Security Vendors19:30 – What $1 Billion Would Do for Global Resilience20:40 – Final Message: No Fear, Just ReadinessSubscribe for expert insights on AI, quantum, and industry transformation.Learn more about how SandboxAQ is shaping the future: https://www.sandboxaq.com.
The Quantum Internet: Qunnect’s Vision for the Future of Communication SandboxAQ 2025-05-02 | What will the internet look like in a quantum world? Join SandboxAQ VP of Global Outreach, Fernando Dominguez Pinuaga, and sit down with Qunnect, a pioneering company building the infrastructure for the quantum internet, one entangled photon at a time. Led by CEO Noel Goddard and Chief Scientist Mehdi Namazi, Qunnect is turning groundbreaking research into real-world quantum networking products. From entanglement distribution over telecom fiber to quantum-secure communications and quantum memory, this conversation explores: -What quantum networking actually means -Why Qunnect’s approach is radically different -The future of connecting quantum computers and sensors -Why now is the time to invest in quantum infrastructure -How Qunnect is preparing for the “GPT moment” of quantum techWhether you're a tech exec, investor, or just quantum-curious, this is a rare look into the next wave of the internet and the people making it happen.Chapters:00:00 – Intro to Qunnect and the Quantum Networking Landscape01:00 – Meet the Founders: From Lab to Startup02:15 – What Makes Qunnect’s Team and Approach Unique05:00 – Explaining the Latest Product: Quantum Entanglement Rack System07:25 – The Quantum Internet Analogy Explained09:30 – Augmenting — Not Replacing — the Internet with Quantum11:00 – Beyond QKD: Infrastructure for All Quantum Applications13:00 – Why the Future of Security Needs Quantum15:30 – Connecting Quantum Devices: Sensors, Computers and More17:15 – Why Investors Should Care Now20:00 – Quantum Memories & Repeaters24:00 – The “GPT Moment” for Quantum: What Will It Take?26:30 – Quantum Security vs. Post-Quantum Algorithms28:00 – What $1 Billion Would Unlock for Qunnect30:00 – Final Thoughts: Why Quantum Is Today’s Smartest Long BetSubscribe for expert insights on AI, quantum, and industry transformation.Learn more about how SandboxAQ is shaping the future: https://www.sandboxaq.com.
How to Eliminate Crypto Chaos & Secure Non-Human Identities | Mo Aboul-Magd + AQtive Guard SandboxAQ 2025-04-28 | Modern cybersecurity depends on strong cryptography and secure machine-to-machine communication — but most organizations lack full visibility into their secrets, certificates, and non-human identities.In this webinar, Mo Aboul-Magd, VP of Product for the Cybersecurity Group at SandboxAQ, explores practical frameworks to consolidate cryptographic assets, improve visibility across IT and security silos, and apply compliance standards efficiently. He also shows how AQtive Guard unifies these capabilities in one platform—delivering deeper observability without disrupting your existing infrastructure.Learn and request a demo: aqtiveguard.com/lp/demo
Jack Hidary on CNBC: The New NVIDIA Collaboration SandboxAQ 2025-04-23 | Jack Hidary, CEO of SandboxAQ, unpacks the company’s new strategic partnership with NVIDIA and how it unlocks a 4x boost in AI performance through cloud-based supercomputing. Jack explains why Large Quantitative Models (LQMs)—not LLMs—are driving breakthroughs in biopharma, materials science, cybersecurity, and the sectors behind 80% of global GDP.Jack also explores the rise of 1 billion autonomous AI agents, the cybersecurity risks they pose. He notes that SandboxAQ will share important news at the RSA Conference aimed at addressing these emerging threats. From robotics reshaping manufacturing to the evolving trade landscape, this interview is a look at what’s next in AI, quantum, and the future of industry.Chapters:00:00 – NVIDIA + SandboxAQ Partnership00:30 – 4x AI Speedup with GPU Supercomputing00:50 – Why LQMs Beat LLMs for Real-World Impact03:02 – Rise of 1 Billion AI Agents04:07 – Security Threats and What’s Coming at RSASubscribe to our channel for more expert insights on quantitative AI and quantum technologies.
Jack Hidary on FOX: How AI & Quantum Are Powering U.S. Innovation, Biopharma & National Security SandboxAQ 2025-04-19 | Jack Hidary, CEO of SandboxAQ, joins FOX Business with Maria Bartiromo to discuss how the company’s partnership with NVIDIA is accelerating AI-driven breakthroughs across biopharma, finance, cybersecurity, navigation, and advanced materials.Jack explains how SandboxAQ has raised $950 million from investors like Google, NVIDIA, and Ray Dalio, and how its Large Quantitative Models (LQMs), not LLMs, are being used to dramatically reduce the cost of drug development, manage financial risk, and strengthen national security.He also introduces agentic AI — autonomous software agents that operate in the cloud to solve complex scientific and industrial challenges, including designing cancer treatments and supporting next-gen manufacturing.This conversation highlights how AI isn’t just changing technology — it’s reviving U.S. industry, boosting productivity, and reshaping the foundation of America’s economic leadership.Subscribe to our channel for more insights on Quantitative AI and Quantum technologies.Chapters:0:00 – Jack Hidary on FOX: AI Partnership with NVIDIA 0:30 – U.S. AI & Chip Leadership 1:30 – What AI can do for the US Economy 3:00 – US Lead in AI and Advanced-Manufacturing3:45 – AI in Biopharma 4:20 – SandboxAQ's Latest Funding5:06 – LQMs Are the Future of AI5:40 – Agentic AI, Drug Discovery & Future of Robotics
Jack Hidary’s vision on AI, Large Quantitative Models, and the road ahead SandboxAQ 2025-04-16 | Jack Hidary, CEO of SandboxAQ, shares his vision for the next evolution of AI: Large Quantitative Models (LQMs). In this forward-looking talk, he reveals how SandboxAQ is partnering with NVIDIA to harness cloud supercomputing, powered by GPUs, TPUs, and soon QPUs, to address some of the world's most complex problems.Jack discusses the core drivers of SandboxAQ’s success: exceptional talent, strong customer alignment, and a new round of funding that fuels rapid advancement. He explores how this momentum is unlocking breakthroughs across industries - from drug discovery to materials science and many other areas, pushing the boundaries of what quantitative AI and quantum technologies can achieve together.Learn more at: sandboxaq.com/lqm
How Large Quantitative Models Are Accelerating Breakthroughs in Pharma and Materials SandboxAQ 2025-04-16 | In this interview, Nadia Harhen, General Manager of SandboxAQ’s AI Simulation division, explains how Large Quantitative Models (LQMs) are reshaping R&D for enterprises operating at the cutting edge of drug discovery and materials development.Unlike traditional AI models that rely on existing data patterns, LQMs are built to uncover solutions where the answers don’t yet exist. Nadia highlights how SandboxAQ’s customers are achieving transformative results, compressing R&D timelines from years to weeks by integrating LQMs into their research pipelines.She shares insights into SandboxAQ’s strategic engagement model, which emphasizes deep collaboration and seamless integration into enterprise workflows. Nadia also discusses the broader AI inflection point we're experiencing today - why it matters, and why forward-thinking organizations must act now to remain competitive.Learn more at: sandboxaq.com/solutions/aqbiosimSee Infographics:go.sandboxaq.com/InfographicHighPerformance.htmlgo.sandboxaq.com/InfographicOrbitalOptimization.html#AQChemsim #AQBiosim
Breaking Boundaries in Quantum Chemistry - Dr. Martin Ganahl on two revolutionary research papers SandboxAQ 2025-04-16 | Join Dr. Martin Ganahl, Lead Scientist at SandboxAQ, as he discusses two revolutionary research papers developed in collaboration with NVIDIA, SandboxAQ, and top academic institutions. The algorithms outlined in the papers achieve up to 80x acceleration in quantum chemistry calculations and more than double the size of feasible molecular simulations, opening doors to advancements in Quantum chemistry that were out of reach just a few years ago.Dr. Ganahl explains how new tensor algorithms for strongly correlated molecules enable ab initio predictions with minimal data, bringing high-accuracy, scalable molecular modeling to a wider range of chemical systems. Discover how these innovations are reshaping the future of materials science, pharmaceuticals, and beyond.Read Dr. Ganahl's papers here:"Parallel Implementation of the Density Matrix Renormalization Group Method Achieving a Quarter petaFLOPS Performance on a Single DGX-H100 GPU Node" Paper: pubs.acs.org/doi/10.1021/acs.jctc.4c00903Infographic: go.sandboxaq.com/InfographicHighPerformance.html"Orbital optimization of large active spaces via AI-accelerators"Paper: arxiv.org/abs/2503.20700Infographic: go.sandboxaq.com/InfographicOrbitalOptimization.htmlLearn more at: sandboxaq.com/lqm
From Chatbots to Scientific Breakthroughs: The Future of AI with LQMs SandboxAQ 2025-04-14 | What comes after chatbots? A new era of AI is here—and it’s grounded in science, not language.In this dynamic discussion, Steve Nouri (Founder, GenAI Works) and Dr. Stefan Leichenauer (VP of Engineering, SandboxAQ) unpack how AI is shifting from content generation to real-world impact. The spotlight is on Large Quantitative Models (LQMs)—AI systems that simulate physical, chemical, and biological systems with high fidelity.While Large Language Models (LLMs) can summarize documents or pass licensing exams, they fall short when it comes to physical reasoning. They weren’t built to understand energy systems, molecular interactions, or new materials.That’s where LQMs come in. Trained on quantitative data and grounded in the laws of physics and chemistry, LQMs are enabling breakthroughs in biopharma, materials science, and clean energy.Steve and Stefan discuss how this new wave of AI is already reshaping R&D across critical industries—and why organizations that rely solely on generative AI risk falling behind.Learn how LQMs simulate, predict, and accelerate discovery in ways that LLMs never could. Learn more at http://sandboxaq.com/lqm
The Future of AI: Hype vs. Reality | Jack Hidary on CNBC SandboxAQ 2025-03-23 | The future of AI isn’t just chatbots - it’s powerful reasoning models, quantum tech, and industry-wide disruption. In this conversation, SandboxAQ CEO Jack Hidary breaks down the next wave of AI and quantum advancements, from NVIDIA’s Blackwell chip to the real-world impact of reasoning models. With AI shifting from consumer applications (like ChatGPT) to B2B transformations in healthcare, energy, and cybersecurity, the stakes have never been higher. Plus, what’s the real timeline for quantum computing? Nvidia says 5-15 years, and major players like Google and Microsoft are racing to get there. Tune in to learn where AI is headed next and why it matters for industries worldwide.Chapters:0:00 – Intro: AI’s Next Leap Begins0:16 – Is AI Overhyped or Just Getting Started?0:46 – NVIDIA’s Blackwell Chips: The Next Powerhouse1:49 – Why AI Needs 150x More Compute Power2:10 – Quantum X Chip: What It Means for AI & Data Centers2:46 – NVIDIA’s Big Quantum Play: Hype or Reality?3:25 – Quantum Computing’s Timeline4:44 – Google, Amazon & Microsoft’s Quantum Breakthroughs6:02 – AI’s Next Shift: From Consumer to Enterprise6:47 – How AI Will Transform Pharma, Energy & Automakers7:32 – The AI & Quantum Arms Race in Cybersecurity8:22 – The Future: AI, Quantum & Flying Cars?9:07 – Closing Thoughts: What’s Next for AI & Quantum?Subscribe for expert insights on AI, quantum, and industry transformation.Learn more about how SandboxAQ is shaping the future: https://www.sandboxaq.com.
Uncharted Conversations with Silvia Bianchi & Teresa Shea SandboxAQ 2025-03-17 | Join us for a groundbreaking discussion featuring industry experts Teresa Shea and Silvia Bianchi to celebrate Women’s History Month.Dive into an inspiring conversation with two powerhouse leaders who have shaped national security, influenced aerospace innovation, and guided the development of cutting-edge AI solutions. This is your chance to gain unique insights, hear firsthand experiences, and ask questions about the future of national security, aerospace, and careers in STEM.Learn more about SandboxAQ at sandboxaq.com
AI explained - LQMs | AI Anchored in the Physical World SandboxAQ 2025-03-13 | Large Language Models (LLMs) like ChatGPT have mastered language, but what about quantitative problems? Grounded in scientific principles and mathematical rigor, Large Quantitative Models (LQMs) are leading the next wave of AI innovation.In this video, we explore how LQMs are transforming our ability to understand, model, and influence the physical world. From deciphering complex equations to driving breakthroughs in science and technology, LQMs represent the cutting edge of artificial intelligence.Tune in to hear about how LQMs work and how they can be used for real-world applications. If you’re wondering what comes next after LLMs, be sure to check this video out!Want more AI content? Check out youtube.com/playlist?list=PLMsyYLfyvI2EhjezKzgv1pWtYqy-w1FzGCurious about SandboxAQ? Visit sandboxaq.com
Beyond LLMs: Meta’s Yann LeCun & Jack Hidary on AI’s future | WEF 2025 SandboxAQ 2025-03-11 | Why can AI pass the bar exam but still struggle with basic physics?At WEF 2025 in Davos, Jack Hidary, CEO of SandboxAQ, caught up with Yann LeCun, Chief AI Scientist at Meta, to explore the next frontier of AI—going beyond Large Language Models (LLMs) to truly understand the physical world.While LLMs excel at generating text, composing haikus, and even passing professional exams, these models still fail at basic real-world reasoning—like understanding gravity or object permanence. Yann explains why this kind of AI struggles with continuous, real-world data and introduces JEPA (Joint Embedding Predictive Architecture)—an innovative approach that aims to teach AI how the world actually works instead of just predicting the next word in a sentence.Jack and Yann also dive into AI’s role in scientific discovery, discussing how Large Quantitative Models (LQMs) are accelerating breakthroughs in drug discovery, materials science, and fundamental physics. With major challenges like Alzheimer’s and pancreatic cancer still lacking effective treatments, organizations must look beyond language models to help solve the world’s most complex scientific problems.Chapters:00:00 - Intro: Jack Hidary & Yann LeCun at Davos 202501:20 - Beyond LLMs: Why today’s AI struggles with real-world reasoning02:00 - Introducing JEPA: A new approach to predictive AI03:37 - AI for science: How LQMs are transforming drug discovery & physics06:00 - The future of AI & the pursuit of true intelligenceDon’t miss this engaging conversation on the future of AI.Subscribe for more insights on AI, quantum, and scientific breakthroughs.Learn more about how SandboxAQ is leveraging quantitative AI to solve some of the world’s greatest challenges: https://www.sandboxaq.com.
Saudi Arabia, AI, and the Future of Global Partnerships | Jack Hidary on CNN International SandboxAQ 2025-03-11 | In this quick chat, SandboxAQ CEO Jack Hidary and CNN International anchor Zain Asher discuss Saudi Arabia's ambitions to diversify its economy, highlighting how AI will shape future partnerships. The Saudis are investing heavily in the US, and there is a growing collaboration between the two countries around AI and tech. Listen in to hear about SandboxAQ and Aramco’s plans to leverage quantitative AI for new carbon materials.Key insights include: 🔹 The evolving partnership between Saudi Arabia and the United States in AI and technology. 🔹 How Saudi Arabia's investments in the U.S.could transform bilateral relationships. 🔹 The role of AI in advancing sectors like biotech, energy, and materials science.This content first appeared on CNN International.Subscribe for expert insights on AI, quantum, and industry transformation.Learn more about how SandboxAQ is shaping the future: https://www.sandboxaq.com.
The future of cybersecurity and biopharma | Jack Hidary & Anthony Viel at WEF 2025 SandboxAQ 2025-03-06 | How are AI and quantum technologies transforming industries and improving lives?At the 2025 World Economic Forum in Davos, SandboxAQ CEO Jack Hidary and Deloitte Canada and Chile CEO Anthony Viel discuss our expanding partnership and our shared mission to drive deep impact at scale. With three years of collaboration behind us and a bold vision for the future, our partnership aims to set new standards for innovation in cybersecurity, biopharma, and beyond.In this engaging conversation, Jack and Anthony explore how AI-powered technologies are reshaping industries. They explore the efficiency gains delivered by language models and the game-changing value created by Large Quantitative Models (LQMs), which are accelerating breakthroughs in biopharma—cutting drug development timelines by a decade and saving lives in the process.The discussion also tackles the critical importance of cybersecurity in today’s digital economy. With tools like SandboxAQ’s Active Guard 2.0, the partnership is helping organizations defend against AI-driven cyber threats today and prepare for quantum-powered challenges tomorrow.Chapters:00:00 - Intro: Jack Hidary and Anthony Viel at Davos 202500:33 - How SandboxAQ and Deloitte are expanding their partnership00:46 - Protecting the digital economy with AI and quantum readiness02:05 - LQMs: Accelerating biopharma breakthroughs and saving livesDiscover how SandboxAQ and Deloitte are partnering to shape the future with AI, quantum, and cybersecurity.Subscribe to stay informed on the latest advancements in AI and quantum technology. Learn more about SandboxAQ’s transformative solutions at: https://www.sandboxaq.com.#artificialintelligence #cybersecurity #cybersecurityrevolution #wef2025
AI & the future of banking | BNP Paribas’ Jean-Yves Fillion & Jack Hidary at WEF 2025 SandboxAQ 2025-03-04 | How is AI revolutionizing banking, risk management, and customer engagement?At World Economic Forum 2025 in Davos, Jack Hidary, CEO of SandboxAQ, joins Jean-Yves Fillion, Vice Chairman Board of Directors of BNP Paribas USA, to explore how quantitative AI and digital transformation are reshaping the banking industry.BNP Paribas has been at the forefront of AI adoption in financial services since 2016, using advanced AI tools for risk management, fraud detection, and customer experience enhancement. Jean-Yves explains how AI is improving anti-money laundering (AML) and know-your-customer (KYC) processes, while Large Quantitative Models (LQMs) are optimizing portfolio management and transaction security.The conversation also touches on BNP Paribas’ global footprint and community engagement, including its long-standing sponsorship of tennis as a platform for fostering inclusion and supporting underprivileged youth. Jean-Yves shares how BNP’s partnerships with John and Patrick McEnroe, Billie Jean King, and public tennis initiatives are giving thousands of children access to opportunities beyond the court.Chapters:00:00 - Intro: Jack Hidary & Jean-Yves Fillion at Davos 202500:45 - How BNP Paribas has used AI in banking since 201601:57 - LQMs, risk management & AI’s role in financial security02:54 - BNP Paribas & tennis: The universal language of sports04:34 - Building successful teams and global partnerships05:37 - How BNP Paribas supports communities through sports07:03 - BNP Paribas & SandboxAQ: The three Cs of successFind out how AI is shaping the future of banking, customer experience, and community engagement.Subscribe for more insights on AI, quantum, and financial innovation.Learn more about how SandboxAQ is transforming industries: https://www.sandboxaq.com.
Tech Darwinism in the Quantum Race | Jack Hidary on CNBC SandboxAQ 2025-03-04 | The AI arms race is accelerating and now quantum computing is catching up. SandboxAQ CEO Jack Hidary discusses quantum competition in Big Tech and how the AI revolution is forcing the Magnificent 7 to rethink their strategy. Meta is challenging OpenAI with a new platform, while Amazon, Google, and Microsoft push forward with quantum chip advancements. Jack breaks down what this means for Big Tech, the future of AI, and growing cybersecurity risks. Will NVIDIA join the quantum race? And how soon could quantum computing threaten blockchain security? A must-watch discussion on the shifting landscape of AI and quantum. Chapters:00:00 - Intro: Quantum developments heat up the AI arms race00:47 - AI’s big players: A fight for dominance02:14 - Can multiple AI giants win?02:54 - The quantum computing boom04:32 - NVIDIA’s quantum position04:58 - Post-quantum cryptography and the blockchainSubscribe for expert insights on AI, quantum, and industry transformation.Learn more about how SandboxAQ is shaping the future: https://www.sandboxaq.com.
IDOLpro: Generative AI for Chemistry | Tech talk with Amit Kadan SandboxAQ 2025-02-27 | SandboxAQ AI scientist Amit Kadan gives a deep dive into IDOLpro, a generative chemistry AI combining diffusion with multi-objective optimization for structure-based drug design. IDOLpro can generate molecules for a range of important disease-related targets with better binding affinity and synthetic accessibility than any molecule found in virtual screens while being over 100x faster and less expensive to run.Read the full paper here: arxiv.org/abs/2405.11785Learn more about all of the other deep tech work happening at SandboxAQ in our publication library:pub.sandboxaq.com
How AI is transforming energy & biotech | Jack Hidary on Bloomberg TV SandboxAQ 2025-02-27 | Can AI help turn carbon emissions into valuable products to help tackle climate change?On Bloomberg TV’s Horizons Middle East & Africa, Jack Hidary, CEO of SandboxAQ, joins Joumanna Bercetche to discuss how AI and quantum technologies are transforming energy, sustainability, and economic growth in the Gulf region.Jack highlights SandboxAQ’s partnership with Saudi Aramco, where Large Quantitative Models (LQMs) trained on chemistry and catalysts are helping convert carbon emissions into high-value materials like carbon composites for automotive, aerospace, and industrial applications. Instead of focusing solely on carbon sequestration, he explains how AI enables carbon capture and up-valuing (CCU)—a game-changing approach for sustainability and economic growth.The discussion also covers AI’s growing role in energy optimization, battery technology, and biotech innovation across the Middle East. With governments in Saudi Arabia, the UAE, and Bahrain investing in AI-powered biotech, the region is positioned to develop its own IP in biopharma and diagnostics, rather than relying on imports.Jack also shares insights on AI’s long-term deflationary impact on global markets, explaining how B2B AI is already reducing costs in housing, food, agriculture, and essential goods—a factor that economists may not yet fully appreciate.Chapters:00:00 - Intro: AI’s impact on sustainability & economic growth00:47 - Large Language Models (LLMs) vs Large Quantitative Models (LQMs)02:20 - Turning carbon emissions into high-value materials with AI04:05 - AI’s role in energy, battery storage & resilient power grids04:54 - B2B AI and its deflationary impact on global markets05:43 - AI-driven biotech innovation in Saudi Arabia, UAE & BahrainFind out how AI is transforming energy, biotech, and global economic trends.Subscribe for expert insights on AI, quantum, and industry innovation.Learn more about how SandboxAQ is shaping the future: https://www.sandboxaq.com.
How AI is transforming wealth management | Jack Hidary & Andrew L. Cohen at Davos 2025 SandboxAQ 2025-02-27 | How is AI reshaping wealth management and client experiences?At the 2025 World Economic Forum in Davos, SandboxAQ CEO Jack Hidary joins Andrew L. Cohen, Executive Chairman, Global Private Bank, JP Morgan, to explore how AI is transforming the financial sector. This compelling conversation highlights the intersection of cutting-edge innovation and personalized client services in wealth management.Jack and Andrew discuss the power of Large Language Models (LLMs) in improving employee efficiency and enhancing the client experience. The conversation then turns to the next frontier of AI innovation—Large Quantitative Models (LQMs)—and how they are optimizing portfolios and delivering long-term value for clients.This engaging discussion provides a unique perspective on how financial institutions like JP Morgan are leveraging AI to empower employees, deliver better outcomes for investors, and navigate rapidly evolving markets.Chapters:00:00 - Intro: Collaboration between SandboxAQ and JP Morgan00:28 - The rise of AI in wealth management and client services01:13 - LLMs and eliminating repetitive tasks for employees01:48 - LQMs: Optimizing portfolios and creating client valueDiscover how quantitative AI is revolutionizing wealth management and shaping the future of personalized finance.Subscribe to stay updated on the latest breakthroughs in AI and quantum technology. Learn more about SandboxAQ’s innovative solutions at: https://www.sandboxaq.com.
Category Theory and LLMs | Tech talk with Tai-Danae Bradley SandboxAQ 2025-02-21 | What is category theory, and what does it have to do with Large Language Models (LLMs)? Join Tai-Danae Bradley, Research Mathematician at SandboxAQ, as she describes a connection, starting with a friendly introduction to this modern branch of mathematics and closing with a new result on categorical magnitude, which is joint work with mathematician Juan Pablo Vigneaux (Caltech).Originating in the 1940s, category theory provides a framework or “template” that unites many ideas, constructions, and themes across the mathematical landscape. A category theoretical viewpoint can also extend to disciplines outside of mathematics, providing new ways to think about new (and old) problems. Mathematical structure in natural language is one example, as some ideas behind today’s large language models seem to be pleasantly compatible with existing tools in category theory. If you're interested in learning more, watch Tai-Danae's full talk at UCLA here:youtube.com/watch?v=KCtyiE6YbncAnd you can check out the papers referenced in the video here:arxiv.org/abs/2106.07890arxiv.org/abs/2501.06662Learn more about all of the other deep tech work happening at SandboxAQ in our publication library:pub.sandboxaq.com
Partnering for secure innovation: Deloitte & SandboxAQ at WEF 2025 SandboxAQ 2025-02-20 | AI and data are transforming industries. Learn how Deloitte and SandboxAQ are partnering for innovation—while ensuring security every step of the way.At the 2025 World Economic Forum in Davos, Robert Williams, Head of Revenue & Partnerships at SandboxAQ, and Anthony Viel, CEO of Deloitte Canada, discuss how their expanded partnership is delivering transformative solutions across life sciences, banking, and government. Together, they explore the twin pillars of AI and cybersecurity, showcasing how secure, data-driven foundations are critical for enabling scalable and ethical innovation.This dynamic conversation highlights how SandboxAQ and Deloitte are accelerating progress in life sciences—cutting the typical 15-year drug development timeline by two-thirds—and empowering organizations with trusted, bias-free AI solutions. By focusing on secure, multidisciplinary collaboration, the partnership is driving innovation while addressing the challenges of today’s digital age.Chapters:00:00 - Intro: Robert Williams and Anthony Viel at Davos 202500:47 - Expanding the SandboxAQ and Deloitte partnership02:25 - The role of AI in life sciences and accelerating drug development03:00 - Why multidisciplinary partnerships are critical for transformation03:38 - Ensuring secure and bias-free AI solutions for clientsLearn how SandboxAQ and Deloitte are revolutionizing industries with AI and cybersecurity—delivering secure, transformative innovations.Subscribe to stay updated on the latest breakthroughs in AI and cybersecurity. Discover how SandboxAQ is solving global challenges at: https://www.sandboxaq.com.#artificialintelligence #wef2025
The future of AI: From efficiency to breakthroughs | Ramesh Raskar & Jack Hidary at WEF 2025 SandboxAQ 2025-02-19 | Will AI evolve from a tool to being an engineer and or a scientist?SandboxAQ CEO Jack Hidary caught up with Ramesh Raskar, Associate Director of the MIT Media Lab, at the 2025 World Economic Forum in Davos to explore how AI and quantum technologies are transforming discovery, mentorship, and collaboration across disciplines.Jack and Ramesh discuss Ramesh’s groundbreaking work at MIT, including their shared vision of AI as more than just a tool for efficiency. Ramesh shares how AI is evolving into both an engineer capable of refining simulations and a scientist tackling the vast unknowns in biology, chemistry, and medicine. By blending creativity, engineering, and science, AI is poised to revolutionize how we approach complex problems.The conversation also highlights Ramesh’s dedication to mentoring the next generation of innovators and his reflections on the Indian concept of Jugaad—solving challenges with creativity and resourcefulness. He explains why moving beyond this approach to a more structured, scientific mindset is key to unlocking AI’s full potential.Chapters:00:00 - Intro: Jack Hidary and Ramesh Raskar at Davos 202500:38 - Balancing science, engineering, and creativity in innovation02:15 - Mentoring the next generation of scientists and innovators03:46 - AI for science: Beyond language models to quantitative breakthroughs05:46 - Quantum-inspired simulations for drug discovery and material science06:46 - Moving from ""Jugaad"" to a scientific mindset in AI innovationLearn how Ramesh Raskar’s innovative ideas and mentorship are shaping the future of AI, science, and collaboration.Subscribe to stay informed on the latest advancements in AI and quantum technologies. Learn more about SandboxAQ’s transformative solutions at: https://www.sandboxaq.com.How will AI and quantum revolutionize science and discovery?SandboxAQ CEO Jack Hidary and Ramesh Raskar, Associate Director of the MIT Media Lab, connect at the 2025 World Economic Forum in Davos to explore how AI and quantum technologies are transforming how we approach science, engineering, and discovery. This insightful conversation highlights the shift from AI as a tool for"
Large quantitative models - the next phase of AI | Jack Hidary on CNBC SandboxAQ 2025-02-15 | Global AI competition is driving a deflationary wave—so why is demand for NVIDIA and AMD chips still surging?On CNBC’s Worldwide Exchange, Jack Hidary, CEO of SandboxAQ, joins Frank Holland to break down the deflationary impact of AI, China's disruptive gains in the global AI race, and how demand for high-performance chips continues to soar.Jack explains why AI is expected to drive down costs across industries, yet paradoxically, the demand for AI infrastructure such as GPUs keeps rising. He dives into Jevons’ paradox, a key economic principle that helps explain why AI’s efficiency gains lead to even greater compute demand. The conversation also covers DeepSeek AI’s advancements in China and how nations are racing to secure dominance in AI, quantum computing, and semiconductor manufacturing.The discussion then shifts to the next phase of AI beyond Large Language Models (LLMs). Jack introduces Large Quantitative Models (LQMs)—AI trained on chemistry, biology, and physics—which are accelerating drug discovery, optimizing energy systems, and transforming global industries. He also highlights SandboxAQ’s expanded partnership with Deloitte, bringing AI-powered solutions to biopharma and beyond.Chapters:00:00 - Intro: Jack Hidary on AI’s global impact01:15 - Beyond LLMs: Large Quantitative Models (LQMs) in biopharma and energy02:02 - AI’s deflationary effect on the global economy02:18 - SandboxAQ & Deloitte’s AI partnership in drug discovery03:40 - Quantum stocks, AI infrastructure & global AI competition04:48 - Jevons’ paradox: AI efficiency vs. compute demandAI is reshaping global markets—find out how it’s impacting industries, investment, and innovation.Subscribe for expert insights on AI, quantum, and industry transformation.Learn more about how SandboxAQ is shaping the future: https://www.sandboxaq.com.
How AI is reshaping global finance & cybersecurity | EY & SandboxAQ at WEF SandboxAQ 2025-02-13 | How can AI transform tax policy, capital decisions, and cybersecurity?At WEF 2025 in Davos, Robert E. Williams, Head of Business & Partnerships at SandboxAQ, joins with Marna Ricker, Global Vice Chair – Tax at EY, to discuss the game-changing impact of AI, Large Quantitative Models (LQMs), and cybersecurity in finance, tax policy, and corporate decision-making.With over two billion tax laws globally, organizations and governments are looking for better predictive tools to make informed capital decisions. Marna highlights how LQMs offer powerful simulation and optimization capabilities that help businesses and policymakers navigate complex regulatory landscapes and drive smarter financial strategies.The conversation also explores cybersecurity in the AI and quantum era, as sensitive financial data must be protected to from next-generation cyber threats. Marna and Robert discuss how EY and SandboxAQ’s partnership is bringing cutting-edge security solutions to the forefront, ensuring AI and quantum innovations are implemented safely and securely.Chapters:00:00 - Intro: Robert Williams & Marna Ricker at Davos 202500:29 - AI & tax policy: How LQMs are transforming financial decision-making00:57 - The power of simulation & optimization for capital investments01:07 - Cybersecurity & AI: Protecting sensitive tax and financial data01:26 - EY & SandboxAQ’s partnership in AI, quantum & security01:34 - A fun Davos moment: Staying up for Ohio State’s big win!Discover how AI and quantum technologies are reshaping global finance, tax strategy, and cybersecurity.Subscribe for more insights on AI, quantum, and cybersecurity breakthroughs. Learn more about how SandboxAQ is shaping the future: https://www.sandboxaq.com.
Investing in AI-driven innovation | Lu Zhang & SandboxAQ at Davos 2025 SandboxAQ 2025-02-11 | AI is transforming industries at an unprecedented pace—but how do we ensure security and global collaboration in this new era?At WEF 2025 in Davos, Robert E. Williams, Head of Business & Partnerships at SandboxAQ, sits down with Lu Zhang, Founder & Managing Partner of Fusion Fund, to explore the massive opportunities AI is unlocking across healthcare, cybersecurity, and industry automation—and the challenges that come with it.Lu shares insights from Fusion Fund’s 100+ portfolio companies, explaining how AI is reshaping industries far beyond tech. From AI-driven medical coding that improves accuracy and cuts costs to advanced AI-powered medical imaging that enhances diagnostics, AI is pushing the boundaries of innovation in regulated sectors like healthcare and finance.But as AI adoption accelerates, so do cybersecurity risks. Robert and Lu discuss how businesses and governments must rethink data security, privacy, and compliance in an AI-powered world. With state-sponsored cyber threats on the rise, Lu highlights why technologies like federated learning and edge computing are becoming essential to protecting sensitive healthcare, financial, and enterprise data—without sacrificing AI’s power to drive innovation.The conversation also dives into the global AI landscape and the importance of collaboration. With nations competing to lead in AI, Lu explains why entrepreneurs must see industry challenges as opportunities to create scalable, global solutions with deep impact.Chapters:00:00 - Intro: Robert Williams & Lu Zhang at Davos 202501:25 - How Fusion Fund is investing in AI-driven industry transformation03:17 - AI’s impact on healthcare: From diagnostics to medical coding05:15 - The cybersecurity risks that come with AI’s rapid adoption06:08 - How federated learning & edge computing improve AI security07:39 - Global AI competition & the power of collaborationThe AI revolution is here—learn how it’s driving innovation, transforming industries, and reshaping global security.Subscribe for more insights on AI, quantum, and cybersecurity breakthroughs. Learn more about how SandboxAQ is shaping the future: https://www.sandboxaq.com.
AI’s global impact: Transforming industries with LQMs | Jack Hidary on Fox Business SandboxAQ 2025-02-10 | Global competition to lead the AI race is heating up as governments and industries look to leverage the next wave of AI innovation—going beyond cost savings to unlock real-world value creation.On Fox Business' Mornings with Maria, Jack Hidary, CEO of SandboxAQ, joins Maria Bartiromo to discuss the next wave of AI innovation: Large Quantitative Models (LQMs). While Large Language Models (LLMs) like ChatGPT and DeepSeek dominate headlines, LQMs are unlocking breakthroughs in biopharma, materials science, finance, and national security.Jack explains why AI needs to go beyond language—instead of training on internet text, LQMs are built on chemistry, physics, and biology to solve real-world challenges. From accelerating drug discovery for Alzheimer's and cancer to creating lightweight materials for next-gen vehicles, LQMs are driving tangible impact. He also discusses SandboxAQ’s partnerships with Sanofi, Dow Chemical, Aramco, and Mount Sinai, where AI and quantum technologies are already transforming industries.The conversation shifts to cybersecurity and national security, as Jack warns that AI is being weaponized by state-sponsored adversaries. With quantum and AI-powered cyber threats on the rise, he highlights the urgent need for U.S. businesses and government agencies to invest in AI-driven defense systems.Chapters:00:00 - Intro: Jack Hidary on AI’s rapid evolution01:30 - Beyond LLMs: Why the future is Large Quantitative Models03:10 - AI’s role in drug discovery, materials science, and finance06:20 - SandboxAQ’s partnerships with global industry leaders07:20 - The growing AI-driven cybersecurity threat from China09:22 - How U.S. businesses must prepare for AI and quantum disruptionDiscover how the next wave of quantitative AI is transforming industries.Subscribe to stay updated on AI, quantum, and cybersecurity breakthroughs. Learn more about how SandboxAQ is shaping the future at: https://www.sandboxaq.com.
Quantum threats and cryptographic resilience | Kelly Richdale & Michele Mosca at Davos 2025 SandboxAQ 2025-02-07 | Is your organization ready for quantum threats?At the 2025 World Economic Forum in Davos, Kelly Richdale, Senior Advisor at SandboxAQ and Executive Fellow at WEF, joins Michele Mosca, CEO of evolutionQ, to tackle one of today’s most pressing challenges: building cryptographic resilience in the face of quantum-powered threats.With large-scale quantum computers looming on the horizon, they discuss why organizations need to act now to upgrade their cryptographic systems before it's too late. Michele warns that the timeline for post-quantum cryptography migration is tighter than many realize, and a reactive approach could lead to costly crises.This timely conversation dives into the game-changing innovations in quantum computing and AI, from fault-tolerant quantum systems to quantum network-based defenses. Kelly and Michele also highlight the disconnect between technical teams and leadership when it comes to understanding the systemic importance of cryptographic resilience—and how to bridge the gap before it’s too late.Chapters:00:00 - Intro: Kelly Richdale and Michele Mosca at Davos 202501:00 - Why cryptographic resilience is essential for the digital economy02:36 - Quantum computing’s progress in 202503:20 - Developing quantum-safe cybersecurity strategies 04:06 - Why organizations must start post-quantum migration now05:34 - Governments lead the charge: Setting cryptographic timelines06:10 - Closing the gap between leadership and technical teamsFind out how to future-proof your organization against quantum threats and embrace the next wave of innovation.Subscribe to stay updated on the latest breakthroughs in quantum and AI. Learn more about how SandboxAQ is paving the way for a secure digital future at: https://www.sandboxaq.com.
How AI and quantum are reshaping cybersecurity | SandboxAQ & Accenture at WEF 2025 SandboxAQ 2025-02-06 | The quantum threat to cybersecurity is top of mind for security professionals, especially when combined with growing danger of new AI-driven attacks. How do these powerful technologies work together—for both defense and harm? SandboxAQ and Accenture take you inside our latest co-authored report.At the 2025 World Economic Forum in Davos, Tom Patterson, Managing Director for Emerging Technology Security at Accenture, and Robert E. Williams, Head of Business and Partnerships at SandboxAQ, discuss the intersection of AI and quantum technologies in securing the digital future. Together, they unveil insights from the new report, which highlights the dual role of AI in quantum security—both as a cybersecurity tool and a weapon for adversaries.This engaging conversation dives into the key findings of the report, including:- How AI accelerates the discovery of cryptographic vulnerabilities to secure networks more effectively.- The increasing sophistication of threat actors using AI for targeting and hybrid attacks.- Why organizations must start now to inventory cryptographic assets and plan for long-term resiliency.Tom and Robert also introduce an open-source calculator developed with MIT that helps organizations pinpoint when quantum and AI threats may become critical. The message is clear: The time to act is now.Chapters:00:00 - Intro: Tom Patterson and Robert Williams at Davos 202500:58 - AI’s role in quantum security: Opportunities and threats02:40 - How adversaries use AI in hybrid quantum attacks03:42 - MIT’s risk calculator and the importance of starting cryptographic inventory04:54 - Key Takeaways and next steps Don’t wait—download the co-authored report and start planning for a secure quantum future today.Read the full report here: https://shorturl.at/wfa5OCheck out the calculator: https://futuretech.mit.edu/quantum-economic-advantage-calculatorSubscribe to stay informed on the latest breakthroughs in AI, quantum, and cybersecurity. Learn more about SandboxAQ’s solutions at: https://www.sandboxaq.com.
