Uploaded August 2026 | Updated September 2026, 2 weeks ago
In this Expert Talk, Dr. Bryan Traynor shares insights into Recent genomic and proteomic advances in ALS/FTD.
This session highlights the latest advances in ALS and FTD genetics, genomics, proteomics, and biomarker research. Dr. Traynor discusses how genetic discoveries, plasma proteomics, and emerging diagnostic approaches are improving our understanding of disease biology, supporting earlier diagnosis, and shaping the future of clinical trials and therapeutic development.
Dr. Traynor examines the role of the C9orf72 repeat expansion in ALS and FTD, explores how genetics influences disease variability, and discusses the growing potential of plasma proteomics to identify biomarkers that may enable earlier diagnosis and prevention trials. He also shares insights into drug repurposing research, including ongoing work evaluating acamprosate as a potential therapeutic approach for C9orf72-associated ALS and FTD.
Throughout the discussion, Dr. Traynor highlights how advances in genomics, proteomics, and biomarker discovery are transforming ALS research and helping move the field toward more precise diagnostics, improved clinical trial design, and future targeted therapies.
In this talk, we cover:
• Introduction to ALS and the genetics of ALS/FTD
• The role of the C9orf72 repeat expansion in ALS and FTD
• How genetics influences disease variability
• Plasma proteomics and emerging biomarkers for ALS
• Drug repurposing research and the acamprosate clinical trial
• New approaches to ALS diagnosis and prevention trials
• The future of genomics, proteomics, and precision medicine in ALS research
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#ExpertTalk #EverythingALS #ALSResearch #ALSCommunity #ALS #FTD #Biomarkers #Genomics #Proteomics #Neurology #ClinicalResearch #BryanTraynor
In this Expert Talk, Dr. Bryan Traynor shares insights into Recent genomic and proteomic advances in ALS/FTD.
This session highlights the latest advances in ALS and FTD genetics, genomics, proteomics, and biomarker research. Dr. Traynor discusses how genetic discoveries, plasma proteomics, and emerging diagnostic approaches are improving our understanding of disease biology, supporting earlier diagnosis, and shaping the future of clinical trials and therapeutic development.
Dr. Traynor examines the role of the C9orf72 repeat expansion in ALS and FTD, explores how genetics influences disease variability, and discusses the growing potential of plasma proteomics to identify biomarkers that may enable earlier diagnosis and prevention trials. He also shares insights into drug repurposing research, including ongoing work evaluating acamprosate as a potential therapeutic approach for C9orf72-associated ALS and FTD.
Throughout the discussion, Dr. Traynor highlights how advances in genomics, proteomics, and biomarker discovery are transforming ALS research and helping move the field toward more precise diagnostics, improved clinical trial design, and future targeted therapies.
In this talk, we cover:
• Introduction to ALS and the genetics of ALS/FTD
• The role of the C9orf72 repeat expansion in ALS and FTD
• How genetics influences disease variability
• Plasma proteomics and emerging biomarkers for ALS
• Drug repurposing research and the acamprosate clinical trial
• New approaches to ALS diagnosis and prevention trials
• The future of genomics, proteomics, and precision medicine in ALS research
📲 Download the EverythingALS App
• Google Play: bit.ly/4nXqIYy
• App Store: bit.ly/42tPBmh
Follow EverythingALS:
► Website: everythingals.org
► X: https://x.com/everything_als
► LinkedIn: linkedin.com/company/everythingals
► Facebook: facebook.com/everythingals
► Subscribe for more Expert Talks: youtube.com/@EverythingALS
#ExpertTalk #EverythingALS #ALSResearch #ALSCommunity #ALS #FTD #Biomarkers #Genomics #Proteomics #Neurology #ClinicalResearch #BryanTraynor







![Three Molecular Subtypes of ALS: #ExpertTalk with Dr. Molly Gale Hammell
In this episode of the EverythingALS Expert Talk Series, Dr. Molly Gale Hammell, Associate Professor at the Institute for Systems Genetics, NYU Langone Medical Center, explores the three molecular subtypes of ALS — stress, inflammation, and TDP-43 pathology. She shares insights into how these distinct pathways contribute to ALS progression and potential avenues for targeted treatments.
⏱ Timestamps:
00:00 - Introduction
02:15 - Understanding ALS at a molecular level
05:40 - The role of cellular stress in ALS
12:20 - Inflammation and its impact on disease progression
18:45 - TDP-43 pathology: Key mechanisms and implications
25:10 - Potential therapeutic strategies
30:00 - Q&A and audience discussion
About EverythingALS:
EverythingALS is a patient-focused nonprofit organization dedicated to accelerating the discovery of treatments and a cure for ALS through collaboration, innovation, and empowering patients and researchers.
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#ALS #MolecularSubtypes #TDP43 #Neurodegeneration #EverythingALS #ExpertTalk Three Molecular Subtypes of ALS: #ExpertTalk with Dr. Molly Gale Hammell](https://i.ytimg.com/vi/b8gFKRtmvqc/mqdefault.jpg)


