Medical Animation Showreel 2026 | Random42 Random42 Scientific Communication 2026-09-28 | Medical Animation Showreel 2026 | Random42
Disease State Education Simulator | Interactive Microsite Random42 Scientific Communication 2022-11-17 | This interactive microsite focuses on the education of Otsuka’s Psychiatry & Neurology pipeline and target therapeutic areas. The platform has been developed to function as a website and an iPad-based application.The project involved a central nervous system (CNS) simulator that covers a range of neurological disease symptoms, states, and treatments, focusing on Otsuka’s three main therapeutic areas within their neurology pipeline: Schizophrenia, Major Depressive Disorder (MDD), and Bipolar Disorder.The purpose of the microsite was to develop an easy-to-use, intuitive platform for training healthcare professionals (HCPs).The content produced for this disease simulator includes:• MoD/MoA animations• Interactive disease progression timelines with call-out features• Content surrounding; burden of disease, societal cost/impact diagnosis, including clinical assessment scales for diagnosis, symptoms, and comorbidities, stigma, recovery, and relapse• Search function within the Otsuka CNS SimulatorThis interactive microsite is hosted on the PsychU.org website, a free community and online resource library for mental health.
Random42 Halloween 2022 Random42 Scientific Communication 2022-10-31 | Happy Halloween from everyone at Random42! 🎃🧛♂️🕷️🕸️To get you in the Halloween spirit 👻 our team have created this wonderfully frightening video revealing the darker side of science and medical animation…
Celebrating 30 Years of Excellence | Random42 scientific communication Random42 Scientific Communication 2022-10-05 | Random42 was founded in 1992, meaning 2022 signifies our 30th Anniversary year! To commemorate this momentous milestone, our senior leaders reflect on our history, their experiences and hopes for Random42’s bright future.During the past three decades, we have grown tremendously, and with this, the talent of our team continues to expand. It is the expertise of our growing team that allows us to stay at the forefront of exciting new trends and push what is possible in our industry.With this video, we celebrate all those, past and present, who have helped make Random42 the success it is today. Here’s to another 30 years of creative excellence.To find out more please visit our website - www.random42.com
New 2022 Medical Animation Showreel | Random42 Random42 Scientific Communication 2022-09-14 | For the last 30 years, we have been in a unique position to observe many of the challenges facing modern science. We’ve witnessed countless diseases and disorders, and through medical animation, we take you on an immersive journey, exploring their complex biological processes and explaining how cutting-edge treatments can be used to overcome such conditions. We believe that understanding the complexity of the human body is paramount to developing these solutions. Our new showreel showcases some of the most impactful and dramatic scientific imagery, illustrating numerous diseases and pathways down to the cellular level. The viewer is transported into the human body where they can float alongside red blood cells inside arteries, observe invading pathogens or bacteria replicating exponentially, all at a molecular level. When a drug or device enters the scene, we can see for ourselves how it interacts with the intricate mechanisms of the human body, all illustrated in the highest cinematographic quality.3D medical animation is a powerful tool allowing the visualization of scientific processes, products, and diseases, many of which are not visible to the unaided eye. In recent years, we have seen the emergence of new and evolving diseases creating a more essential need than ever for scientifically accurate, high-quality animation.Scientific technology is constantly improving to aid our quality of life. We are able to demystify the inner mechanisms of the medical advancements that are paving the way for the future, bringing these scientific stories to life in magnificent 3D. Our showreel gives a glimpse into the impressive work our team creates to help explore MoDs and MoAs for a wide range of therapeutic areas.For over three decades Random42 has helped to tell these scientific stories, cultivating innovative and creative approaches to scientific communication. For more information about our capabilities, please visit www.random42.com.
Natural Killer Cell Technology | Scientific Animation Random42 Scientific Communication 2022-07-01 | The purpose of this animation is to educate viewers on Cytovia Therapeutics’ Natural Killer (NK) Cell Technology, discovering how they are harnessing the innate immune system with complementary and disruptive NK-cell and NK-engager antibody platforms. Using vibrant, high-quality visuals the story of NK cells and their potential as cancer-combating therapies is brought to life in 3D. The animation was commissioned to support Cytovia’s investor relations activities, ensuring potential investors could understand and visualize the science behind this concept. Looping clips, video banners, and animation stills can be seen across Cytovia’s entire website, creating a consistent brand identity. Animation assets have also been used to enhance their social media presence. In addition, imagery is displayed throughout the ‘Our Technology’ page, illustrating each step of the journey to develop these therapies.
Aesthetic Injectable Treatment | Scientific Animation Random42 Scientific Communication 2022-06-30 | Vyvanse is a central nervous system (CNS) stimulant used to treat ADHD. This animation uses eye-catching visuals and accurate scientific storytelling to explore the mechanism of action (MoA), focusing on drug delivery, administration options, and dosing, as well as important safety information.The animation was produced in two different aspect ratios, making it suitable for widescreen and mobile use.The animation flows through the natural chapters covering all aspects of this drug, starting at formulation and then following the journey through the body Vyvanse is rapidly absorbed from the gastrointestinal tract into the bloodstream where it circulates. Vibrant, colorful visuals depict the central nervous system (CNS), showing the drug as it passes from the blood to the CNS.The content is summarised in a short concluding segment, providing a simple and brief overview of the chapters. The use of stunning graphics results in an engaging animation that is scientifically accurate as well as visually appealing.The animation is hosted on the Vyvanse pro website, in the ADHD section, within their ‘How Vyvanse is delivered within the body’ segment.Are you interested in seeing how our award-winning medical animation can he
Mechanism of Action Animation | ADHD Random42 Scientific Communication 2022-06-29 | Vyvanse (lisdexamfetamine dimesylate) is a central nervous system (CNS) stimulant used to treat ADHD for patients ages six and above. This animation uses eye-catching visuals and accurate scientific storytelling to explore the mechanism of action of Vyvanse, focussing on drug delivery, administration options, and dosing, as well as important safety information. The animation was produced in two different aspect ratios, making it suitable for widescreen and mobile use.The animation flows through the natural chapters to cover all scientific aspects of this drug, starting at drug formulation and then following the drug through the body. The drug is rapidly absorbed from the gastrointestinal tract and moves to the bloodstream where it circulates. Vibrant, colorful visuals depict the central nervous system, showing the drug as it passes from the blood to the CNS.The content is summarised in a short concluding segment, providing a simple and brief overview of the chapters. The use of stunning graphics results in an engaging animation that is scientifically accurate as well as visually appealing. The animation is hosted on the Vyvanse pro website, in the ADHD section, within their ‘How Vyvanse is delivered within the body’ segment.
COVID-19 Infection and Vaccine Development | Scientific Animation (HD/4K) Random42 Scientific Communication 2022-01-28 | In this video, we explore how COVID-19 vaccines work; first by understanding how SARS-Coronavirus-2 spreads and infects the body, and how vaccines expose our immune system to parts of the virus in order to trigger an antibody response.Please note that facts may change over time as the outbreak is ongoing. Updates can be found at: https://www.who.int/emergencies/diseases/novel-coronavirus-2019If you would like to use this video or any of the scientific imagery shown, for media and/or other purposes, please contact us at info@random42.com.The creation of this video was made possible due to Random42 receiving an Epic MegaGrant towards the end of 2020. This was used to enhance our medical animation and interactive capabilities utilising Epic Games’ Unreal Engine; the world’s most open and advanced real-time 3D creation tool.With this rare opportunity, our team could develop a new real-time approach to our animations that has expanded the possibilities of what we can achieve creatively. The MegaGrant was used to create this educational animation on COVID-19 infection and vaccine development. The animation is a follow-up to our hugely successful Coronavirus Outbreak Animation, which received close to 2 million views and has been featured in various news programmes and documentaries around the world - youtube.com/watch?v=elWIPbDfLA0.
Smoking Cessation Animation Random42 Scientific Communication 2021-11-11 | Nicorette® Mini Lozenges are an over-the-counter (OTC) smoking cessation product that dissolves in your mouth to release therapeutic nicotine that helps reduce the symptoms of nicotine withdrawal. This helps control cravings and provides craving relief associated with quitting smoking. The lozenges are infused with mint to provide a blast of flavor when ingesting.We created this medical animation for GSK to visually explain the science behind the mini lozenge. This OTC animation was created to inform the consumer about the mechanism of action of the lozenges.This consumer animation is hosted on the Nicorette & NicoDerm CQ YouTube Channel freely for users to watch.
Aspirin MoA Animation Random42 Scientific Communication 2021-11-11 | Aspirin is an internal analgesic available as an over-the-counter (OTC) medicine that temporarily relieves minor aches and pains and reduces fevers. Aspirin can also be prescribed to people with heart and circulatory disease to help prevent blood clots.We created this consumer animation for the British Heart Foundation to educate patients on the mechanism of action of aspirin, and to show the important role aspirin plays inside the human body.This medical animation was produced at a documentary pace using eye-catching scientific visuals to create an animation that is easy to follow and understand. The target audience being patients and consumers who want to learn more about the effects and workings of aspirin.The animation is housed on the British Heart Foundation website, within their ‘Heart Matters Magazine’, an online magazine created to help people at risk from heart and circulatory disease and those who care for them. The video is embedded into an article about aspirin, ‘What is aspirin and what does it do in your body?’. The animation can also be found on the British Heart Foundation YouTube Channel.
Non-steroidal Anti-inflammatory Drug Animation Random42 Scientific Communication 2021-11-11 | Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) used to treat pain and inflammatory diseases such as gout. Diclofenac targets inflammation to strike pain at its source and is the active ingredient in the medicinal range of Voltarol products that relieve pain.This medical animation explores the mechanism of action, showing how this NSAID targets key steps in inflammatory cascades. Using impressive scientific visuals, the animation shows how diclofenac reduces inflammation by inhibiting prostaglandin synthesis through action on COX-2 enzymes and inhibiting phospholipase A2 activity to reduce the production of inflammatory leukotrienes, resulting in reduced inflammation and pain.This consumer animation was created for GSK and is found on their Health Partner website under the Voltarol pain relief section, embedded onto the webpage explaining the science behind diclofenac.Stills from the animation can also be found on this page. In addition, the video is hosted on the GSK Health Partner YouTube Channel.
Aspirin Capsule Animation Random42 Scientific Communication 2021-11-11 | VAZALORE is an immediate release aspirin available over-the-counter (OTC). It is the first and only FDA-approved liquid-filled aspirin capsule that uniquely delivers aspirin. This innovative delivery system releases aspirin in the duodenum which subsequently decreases exposure to the stomach, reducing the risk of stomach erosions and ulcers.The capsule provides fast and reliable aspirin absorption to help prevent future heart attacks or clot-related strokes in patients with vascular disease and diabetic patients who are candidates for aspirin therapy. The aspirin also helps relieve aches and pains.This OTC animation was created to explore the mechanism of action (MoA) of the capsules using engaging scientific visuals to explain delivery and absorption, and the benefits in comparison to other aspirin products on the market.This medical animation was created for PLx Pharma to explain the science to consumers, Healthcare Professionals (HCPs), and investors. The animation is hosted on the VAZALORE product page as well as on the VAZALORE HCP website. Stills from the animation can be found on the technology page to help aid the explanation of the drug delivery platform.
Oncology MoA Animation Random42 Scientific Communication 2021-10-21 | We created this mechanism of action (MoA) animation for Novartis for their oncology product, TABRECTA™. TABRECTA™ (capmatinib) tablets are indicated for the treatment of adult patients with metastatic non-small cell lung cancer (NSCLC), whose tumors have a mutation that leads to mesenchymal-epithelial transition (MET) exon 14 skipping.This medical animation, based on in vitro/in vivo studies, uses scientific storytelling to explain the action of TABRECTA™ tablets. The animation uses eye-catching visuals to captivate and engage the viewer. The animation explains METex14 in NSCLC, the role of MET in cell signaling, and capmatinib’s MoA.TABRECTA™ is a kinase inhibitor, operating by blocking a key enzyme that results in helping to stop the tumor cells from growing. This treatment is intended for patients who have NSCLC that has spread to other parts of the body or cannot be removed by surgery, and whose tumors have an abnormal mesenchymal-epithelial transition (MET) gene.This animation is featured online as part of the Novartis website intended for Healthcare professionals (HCPs). The animation is hosted on the TABRECTA™ product page for HCPs to learn more about the product, where they can explore related product resources such as the efficacy, safety profile, product dosing, and administration.
Bone Surgery Animation Random42 Scientific Communication 2021-10-21 | We created various mechanism of action (MoA) animations for DePuy Synthes to visually explain the science behind a variety of their medical devices used for bone surgeries. This includes their TRUMATCH® Graft Cage – Long Bone. The TRUMATCH® Graft Cage animation conveys the science behind this medical product using stunning visuals, in a scientifically accurate, easy to understand and engaging format, highlighting key product features including a basic overview of the underlying procedure.The TRUMATCH Graft Cage – Long Bone is a 3D-printed personalized resorbable implant for the treatment of critical-sized segmental defects. The device is intended to support morselized bone graft and/or bone graft substitutes in large, segmental defects of the humerus, femur, and tibia.The animation is embedded on the product page on the DePuy Synthes website, along with the product explanation, features and benefits, preclinical evidence, and supporting documentation. Stills from the animation also serve as the backdrop for the product page and are also featured throughout the page, unifying the brand.
Combination Immunotherapy Animation Random42 Scientific Communication 2021-10-21 | This mechanism of action (MoA) animation was created for Bristol Myers Squibb to visually convey the science behind their oncology combination treatment, OPDIVO® (nivolumab), and YERVOY® (ipilimumab). This drug combination is indicated for the treatment of advanced melanoma.OPDIVO® + YERVOY® are two immunotherapies that BMS has combined to harness the body’s immune system to fight cancer. The animation tells the story of the combined medications and how they help the body attack cancer by shrinking tumors.OPDIVO® is a monoclonal antibody, an anti-PD-1 drug, that promotes the tumor-killing effects of T-cells. YERVOY® is also a monoclonal antibody, an anti-CTLA-4 drug, that helps strengthen the immune system by promoting the function and growth of T-cells. The combination of these antibodies promotes an enhanced anti-tumor response.This animation is hosted on the OPDIVO® HCP website for healthcare professionals to discover how these drugs work collectively.
Multiple Sclerosis | MoA Animation Random42 Scientific Communication 2021-10-20 | Biogen’s product, VUMERITY® (diroximel fumarate), is a first-line oral treatment indicated for patients with relapsing forms of multiple sclerosis (MS), including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults.Although the mechanism of action of VUMERITY® is not fully understood, its active metabolite (MMF) has been shown to activate the Nrf2 pathway, which is involved in the cellular response to oxidative stress, the cause of pathogenesis of MS.We created this scientific animation to help visualize the science behind this product, to help inform the audience about the mechanism of disease of multiple sclerosis and the action of VUMERITY® in patients.This educational animation features online as part of the VUMERITY® website.
Antiviral Platform Animation Random42 Scientific Communication 2021-10-20 | We produced this medical animation for Cidara Therapeutics to explore their Cloudbreak® antiviral platform which is a fundamentally new approach to treating and preventing viral infections.This mechanism of action (MoA) animation explores this technology platform and its revolutionary approach in the fight against life-threatening infectious diseases. Antiviral Fc-Conjugates (AVCs) are a new class of drugs developed from Cidara’s Cloudbreak® antiviral platform.AVCs have the potential to prevent as well as treat influenza and other life-threatening viral diseases such as those caused by RSV, HIV, and other viral infections. These long-acting AVCs directly prevent viral proliferation whilst simultaneously engaging the immune system, maximizing viral clearance.This animation was created for use as part of Cidara's Investor Relations activities in order to educate potential investors on the science of this platform. Imagery and short clips from the animation have been utilized throughout their corporate presentations. The video has been embedded onto the Cidara Therapeutics website as well as the Cidara YouTube Channel. Imagery from the animation is also found throughout the website, including an annotated image of AVC binding.
Immunotherapy Product Animation Random42 Scientific Communication 2021-10-20 | We created this medical animation for Spectrum Pharmaceuticals for their immunotherapy product, Poziotinib®. The animation begins with the mechanism of disease of EGFR-positive and HER2-positive cancers, exploring how mutations in these genes result in uncontrolled cancer cell growth.Poziotinib® is an investigational, orally-administered, irreversible tyrosine kinase inhibitor targeting EGFR and HER2 with exon 20 insertion mutations. Pre-clinical studies indicate that Poziotinib® inhibits kinase activity of EGFR and HER2 with exon 20 insertion mutations, inhibiting proliferation, and promoting cancer cell death. Poziotinib® is in development for the treatment of Non-Small Cell Lung Cancer (NSCLC) and breast cancer.This animation can be found on the Spectrum Pharmaceuticals website on the Poziotinib® product page. Imagery from the animation can be found throughout the product page. In addition, animation imagery is also used for page banners on the website homepage and the product page.
Cancer Immunotherapy Animation Random42 Scientific Communication 2021-10-20 | Gradalis’ Vigil® Platform is a fully personalized, patient-specific cancer immunotherapy. The Vigil® Platform is indicated for patients with advanced solid tumors and is currently being developed for the treatment of ovarian cancer and breast cancer. The Vigil® Platform uses the patient’s cancer cells to create a personalized cancer immunotherapy that activates the patient’s own T-cells to fight their cancer cells.This mechanism of action (MoA) animation explores this platform using eye-catching visuals, showcasing how the innovative therapy works. The treatment involves surgically removing tumor tissue from the patient. Cancer cells from the tumor are then genetically modified and reintroduced back into the patient. These gene modifications help activate the immune system to detect and kill any cancer cells that may remain locally and in circulation.This medical animation can be found on the Gradalis website on the product page. A looping clip created from animation content is also featured on the website.
Overactive Bladder Animation Random42 Scientific Communication 2021-10-19 | GEMTESA® (Vibegron) is an oral medication indicated for the treatment of overactive bladder (OAB) with signs of urge urinary incontinence (UUI), urgency, and urinary frequency in adults. GEMTESA® is a selective beta-3 adrenergic agonist which activates beta-3 receptors. This binding results in bladder muscle relaxation, increasing bladder capacity, resulting in reduced symptoms of OAB.This animation introduces OAB, the causes of this condition. Using eye-catching visuals, the action of GEMTESA® is explored, highlighting Urovant’s intelligent drug design and three key differentiators. The animation also highlights the action of GEMTESA® in comparison to other anticholinergic treatments which target M3 (muscarinic) receptors. Infographics have also been incorporated for the engagement of data visualization.This medical animation can be found on the homepage of the Urovant medical affairs website. The video is intended for use by US Healthcare professionals (HCPs). The look and feel of the animation are consistent with Urovant’s branding, helping create a strong visual identity.
Irreversible Electroporation Animation Random42 Scientific Communication 2021-09-17 | The NanoKnife® system utilizes the power of irreversible electroporation (IRE). NanoKnife® technology uses this power to destroy diseased tissue. Two or more needle electrodes are positioned in or around the diseased tissue in order for high voltage pulses to be delivered to the tissue, creating nanopores within the cell membrane. This stimulus causes apoptosis in the targeted cells, causing ablation of the diseased tissue.This mechanism of action (MoA) animation uses stunning visuals to convey the science behind this highly precise therapy. The animation explores how this medical device allows for the tailored treatment of diseased soft tissue through surgical ablation.This medical animation can be found on the NanoKnife® product website. The animation is featured on the technology page of the site. Stills from the animation can also be found on the NanoKnife® website, as well as on the product page of the AngioDynamics website.
Mass Cytometry Animation Random42 Scientific Communication 2021-09-07 | CyTOF XT™ is the most technologically advanced mass cytometer to date. It is designed to build on the benefits of mass cytometry technology whilst streamlining operation and automating sample acquisition for the best-timed results and reproducibility from every run.This mechanism of action (MoA) animation was created to visually convey the science behind Fluidigm's apparatus, exploring the key features of their CyTOF™ technology and the CyTOF XT™. The animation uses stunning, eye-catching visuals to give the viewer a closer look at the CyTOF XT™ machine.This scientific animation can be found on the Fluidigm website on the CyTOF XT™ product page, highlighting the advantages of this technology. Stills from the animation can be found throughout the webpage, as well as on the homepage main scroll banner, helping build a clear and strong brand identity.
Random42 AR Stories | App Demo Random42 Scientific Communication 2021-07-02 | The Random42 ‘AR Stories’ app shows how augmented reality (AR) can be used to enhance scientific storytelling, experiencing the microscopic worlds of medical science on any flat surface. Our app demonstrates to the viewer how augmented reality can bring scientific narratives to life in a convenient and engaging format.
Monoclonal Antibody: Gamification VR Experience Random42 Scientific Communication 2021-06-24 | Gameplay screen capture of this high-end Virtual Reality (VR) app, which combines our unique storytelling format with state-of-the-art technology, promoting a detailed understanding of the biological processes involved.In certain disease conditions, such as Diabetic Macular Edema and Age-related Macular Degeneration, there are increased levels of two distinct ligands.This experience is an immersive VR game that illustrates the mechanism of a bispecific monoclonal antibody developed by Roche, which has been designed to target and bind to these ligands.
Autologous Cellular Therapy Animation - Brainstorm Cell Therapeutics Random42 Scientific Communication 2021-02-01 | Brainstorm Cell Therapeutics’ NurOwn® technology platform focuses on life-changing autologous cellular therapies for the treatment of debilitating neurodegenerative diseases, in particular Amyotrophic lateral sclerosis (ALS). Their approach to tackling these diseases uses an innovative cellular therapy approach, ultimately aiming to slow or stabilize disease progression in patients.Random42 produced this scientific animation for Brainstorm Cell Therapeutics to explore their pioneering autologous cellular technology platform (NurOwn®), bringing the science behind this treatment to life using eye-catching and engaging visuals. This animation takes the viewer on a unique journey, exploring ALS pathology, MSC-NTF cell therapy, exosome technology, and NurOwn® treatment in action. The animation also provides an insight into the patient experience whilst receiving treatment.This animation is hosted on the Brainstorm Cell Therapeutics website. Imagery from the animation is also utilized across the site, including the homepage, providing brand consistency throughout.
Disease Hunters Documentary Series - Scientific Animation Random42 Scientific Communication 2021-01-26 | CHANNEL NEWS ASIA – Disease Hunters The Coronavirus Pandemic has brought global attention back to deadly diseases and the urgent need for better understanding, vaccines, and treatments. Channel News Asia (CNA) produced a three-part informative documentary series entitled, “Disease Hunters”, which brings to life the storytelling behind deadly diseases, covering infectious viral, bacterial and Mosquito-Borne diseases.Random42 created a series of scientific animations to support the scientific content of the documentary. These animations feature throughout the three episodes and aim to help viewers visualize the science, encourage a more in-depth understanding, and provide a documentary experience of the highest cinematographic quality.“Disease Hunters” introduces scientists from around the world who are working relentlessly to identify evolving pathogens, combat existing viruses and find vital vaccines and treatments. The series discusses COVID-19, influenza, polio, H1N1 swine flu, malaria, dengue, tuberculosis, and superbugs.The three-part series first aired on CNA in November 2020 and is now available on-demand on the CNA website (channelnewsasia.com/news/video-on-demand/disease-hunters) and YouTube channel. The showreel featured above showcases some of the scientific animations included throughout the three episodes.
Non-Alcoholic Steatohepatitis (NASH) Animation Random42 Scientific Communication 2020-12-18 | Random42 produced this Mechanism of Disease (MoD) animation for Pfizer to take a closer look at Non-alcoholic steatohepatitis (NASH). NASH is liver inflammation and damage caused by an excess build-up of fat in the liver. It is the most severe form of non-alcoholic fatty liver disease (NAFLD) and has links with obesity, metabolic syndrome, diabetes, or a genetic predisposition.NASH is an unfamiliar disease to many patients and can be initially unrecognized by physicians. Pfizer is committed to advancing understanding and treatment of this disease, with this animation adding to the efforts of understanding the science of NASH through visually engaging scientific storytelling.This animation is hosted on the Pfizer website as a featured News segment, ‘A Closer Look at NASH’.
Dry Eye Disease MoA Animation Random42 Scientific Communication 2020-12-18 | Novartis’ product, Xiidra®, is a non-steroid therapy which can disrupt inflammation and has been designed to target the underlying inflammation which is believed to fuel dry eye disease (DED).This Mechanism of Action (MoA) animation was produced to inform the audience about the causes of dry eye disease and how the product could help treat the signs and symptoms of this. With clear branding guidelines set, this project aimed to exceed the client’s expectations by creating an immersive and captivating experience.The animation has featured online as part of the Xiidra® website. The animation has also been included in a virtual booth which explores some of Novartis’ ophthalmology products as part of the 2020 American Academy of Ophthalmology Annual Meeting.
Gamma Delta T-Cell Therapy Animation Random42 Scientific Communication 2020-12-18 | GammaDelta Therapeutics uses the unique properties of Gamma delta T-cells to combat cancer and improve outcomes for patients. Their innovative approach to cancer immunotherapy using Gamma delta T-cells aims to increase the survival of patients with haematological malignancies and solid tumours.We produced this animation for GammaDelta Therapeutics to explore Gamma delta T-cells and their ability to kill cancers. The animation captures the unique and powerful characteristics of Gamma delta T-cells and their use in allogeneic therapy to target tumour cells without harming healthy cells.The animation visually illustrates the science behind Gamma delta T-cells and how they play an important role in anti-tumour responses by triggering an adaptive immune response which can eradicate cancerous cells. The different mechanisms by which this occurs are explored within this animation.This animation can be found on the GammaDelta Therapeutics website on the homepage and the science page. Imagery from the animation is found throughout the site, showcasing their innovative cancer immunotherapy.
Precision Medicine Animation - Tissue-Based Comprehensive Molecular Profiling Random42 Scientific Communication 2020-12-18 | This educational animation was created for Caris Life Sciences to tell the story of Tissue-Based Comprehensive Molecular Profiling. As precision medicine becomes a more powerful tool in healthcare, there are still unanswered questions about its meaning and use. Caris Life Sciences has used this novel approach to help cancer patients with the use of tumor profiling. Caris Life Sciences’ molecular profiling can help better patient outcomes by helping find personalized cancer treatments based off of unique characteristics of a person's cancer and genetics. This animation illustrates the molecular analysis tools used to examine a tumor sample, revealing the molecular blueprint of a patients’ tumor. The purpose of this animation is to educate a variety of stakeholders about the Mechanism of Action (MoA) of this molecular intelligence platform. The animation is hosted on Caris Life Sciences’ website, YouTube channel and LinkedIn page.
Medical Animation for Biotechnology | Promote your scientific message to Investors, HCPS & Patients Random42 Scientific Communication 2020-11-27 | Random42 is the global leader in providing digital scientific communication solutions to the pharmaceutical, biotechnology and medical device industry. We bring challenging medical and scientific concepts to life, making them simple, beautiful and easy to digest.The high-quality visuals that we produce can be utilized across multiple channels to support investor relations, corporate communications and other marketing activities, providing both brand consistency and a huge return on investment.Founded in 1992, Random42 is the largest and most experienced company within the industry and has won over 200 awards for high-quality medical animation and scientific storytelling.Please visit our website for further information - random42.com
Animal Health Animation Showreel Random42 Scientific Communication 2020-06-26 | Random42 transforms complicated science into concise documentaries and digital solutions to clearly articulate core messages behind animal research pipelines and products.View a selection of our work in the animal health space.For more information visit - random42.com/animal-health-medical-animation
Spinal Fusion Surgery - PEEKplus® technology Animation Random42 Scientific Communication 2020-04-15 | Vallum’s nanotextured PEEK (Polyetheretherketone), PEEKplus® is a disruptive breakthrough innovation in spinal fusion surgery and the first and only FDA cleared Nanotexture on PEEK interbody fusion devices. Nanotextured surfaces, like PEEKplus®, are known to improve osseointegration. Vallum’s Accelerated Neutral Atom Beam (ANAB) process superimposes 20-50 nanometer concavities directly into the surface of PEEK.The objective of the animation was to clearly demonstrate the effect of ANAB processing technology on PEEK at the micro and nanoscale and visually communicate how the cavities created in PEEK promote osseointegration.The animation has been embedded within Vallum’s website homepage, with assets from the animation utilized for banner imagery throughout the website, giving a consistent visual brand identity.
Introduction to the Human Body | The Merck Manuals Series Random42 Scientific Communication 2020-04-15 | This is the Introduction to the Human Body Animation which forms part of the Merck Manuals Series. The Merck Manuals were first published in 1899 as a small reference book for physicians and pharmacists. The Manual grew in size and scope to become one of the world's most widely used comprehensive medical resources for professionals and consumers. As the Manual evolved, Merck realized the need to modernize the approach in order to engage their target audience. To support the current assets, a series of 17 educational, biological animations were developed for the Merck Manuals Consumer website and YouTube Channel. The animations covered a variety of medical topics and were aimed at a target market of consumers with limited previous knowledge of the areas covered. With this target audience in mind, the messages were kept clear, concise and easy to understand. The ‘Intro to the Human Body’ animation has over 11,000 views and the complete collection of 17 videos has over 20,000 views on YouTube alone.
The Science of Nitric Oxide | Consumer Health Animation Random42 Scientific Communication 2020-04-15 | This animation focuses on how Nitric Oxide is naturally produced in the body. A Nobel Prize was awarded for the discovery that Nitric Oxide plays a significant role in the cardiovascular system. This discovery revealed nitric oxide as a vasodilator, helping to reduce blood pressure and increase oxygen in the blood.The animation was created for the BerkeleyLife.com website and for trade use in the US market. The purpose was to engage and inform the audience of the benefits of Nitric Oxide for cardiovascular wellness and the science behind how this works within the body.
Immunoproteasome Animation Random42 Scientific Communication 2020-04-15 | We created a scientific animation for Kezar Life Sciences focusing on the normal function of the multicatalytic immunoproteasome, emphasizing its importance in the body. The animation then illustrates the disease state, whereby the immunoproteasome becomes highly expressed at the sites of inflammation in patients with autoimmune disorders. Lastly, the mechanism of action (MoA) of selective inhibitor of the immunoproteasome, KZR-616, is explained and how it induces a potent anti-inflammatory effect, resulting in symptom improvement and disease remission in Rheumatoid Arthritis, lupus, Multiple Sclerosis, and Inflammatory bowel disease. The purpose of the animation was to provide a visual explanation of the normal function, disease state and MoA of KZR-616 in a comprehensive and engaging manner so that the science and subsequent beneficial outcomes can be clearly understood by the appropriate target audiences. The animation was created for use at industry trade shows and conferences, for corporate fundraising events and investor relations. The video can currently be found on the immunoproteasome section of the Kezar Life Sciences website and visual assets utilized throughout their 2019 Investor Presentation.
Stellarex Drug-Coated Balloon Animation Random42 Scientific Communication 2020-04-14 | The Stellarex drug-coated balloon (DCB) is an angioplasty balloon with EnduraCoat technology allowing treatment of arterial lesions in peripheral artery disease (PAD) with a low drug dose. We developed an animation for Philips showing the mechanism of action (MoA) of their Stellarex DCB platform. The animation follows the therapy device as it is guided along the artery before arriving at the lesion site. It then looks at how the combined effects of the angioplasty balloon and low drug dose target the lesion and allow normal blood flow to resume.The animation is housed on the Philip’s Stellarex product page showcasing it as an innovative image-guided therapy device.
Boron Neutron Capture Therapy Animation Random42 Scientific Communication 2020-04-14 | TAE Life Sciences’ Boron Neutron Capture Therapy (BNCT) is being developed as a non-invasive radiation treatment for the most difficult to treat cancers. It selectively targets cancer cells to spare healthy tissue making it easier to tolerate than other radiation treatments. We created an animation that explains the mechanism of action (MoA) of BCNT concisely and engagingly, which makes its benefits clear. The animation can be found on the TAE Life Sciences’ website to highlight BCNT as a promising new treatment for inoperable, invasive or radioresistant cancers. A looped section of the animation plays on the homepage making the page visually engaging and establishing a consistent brand identity.
Chemotherapy Product Animation Random42 Scientific Communication 2020-04-14 | INFUGEM is a chemotherapy product indicated for ovarian cancer, breast cancer, non-small cell lung cancer (NSCLC) and pancreatic cancer. It is the first chemotherapy product approved by the FDA that is pre-mixed and ready to infuse, eliminating some of the steps involved in traditional chemotherapy preparation.Sun Pharma wanted to show the problems associated with chemotherapy preparation in order to position INFUGEM as a safer choice. This animation highlights these problems, revealing the variability of chemotherapy preparation and the potential health risks to healthcare workers. In doing so, the animation showcases the ease of use and advanced safety benefits of INFUGEM compared to other chemotherapy products.A microsite was also developed to house the animation and provide important safety information - infugem.com/index.html
Tissue Repair Animation - Hyaluronic Acid and HYAFF® Technology Random42 Scientific Communication 2020-04-14 | Anika Therapeutics manufacture products that help protect, heal and regenerate the damaged tissue found in wounds, burns and severe ulcers. The products are based on hyaluronic acid (HA) which is naturally present in the skin and plays a major role in tissue, cartilage and connective tissue repair, as well as functioning as a lubricant and component of the extracellular matrix.Random42 created an animation that shows how Anika Therapeutics’ have adapted HA to create HYAFF – a HA-based material that can be made into 3D scaffolds to support the entrapment, proliferation and differentiation of cells into functional skin, cartilage and bone tissue.The animation appears on the Anika Therapeutics website, where it provides a clear and engaging background to the propriety technology behind their products.
Cold Agglutinin Disease Animation - Mechanism of Disease Random42 Scientific Communication 2020-04-14 | Cold agglutinin disease, (CAD), is a rare form of autoimmune hemolytic anemia, where the body mistakenly recognizes the antigens on the surface of red blood cells as foreign. This leads to extravascular and intravascular hemolysis, and a range of severe symptoms, including acrocyanosis, extreme fatigue, dyspnea and hemoglobinuria.The objective of the animation was to help educate Health Care Professionals on the mechanism of disease for cold agglutinin disease. The animation was used at The American Society of Hematology and is now featured on the Sanofi Genzyme disease education website, understandingcad.com.This animation has won 9 industry awards for the quality of animation.
Drug Target Discovery Technology - Protein Interference Random42 Scientific Communication 2020-04-14 | Phoremost’s technology aims to discover drug targets that remain intractable or undetected using conventional technologies, facilitating drug development for diseases such as cancer. Their novel SITESEEKER platform uses PROTEINi (or protein interference) – a new phenotypic screening method that identifies unexpected druggable sites that aren’t apparent with other technologies.PROTEINi libraries encode millions of different proteins allowing identification of target-interaction sites throughout the whole proteome. Random42’s mechanism of action (MoA) animation for Phoremost shows how PROTEINi uses phenotypic screening to rapidly identify the key target-interaction sites involved in the disease being studied. This allows the discovery of novel drug targets including targets that were previously deemed ‘undruggable’. This animation appears on the Phoremost technology page to showcase the potential of PROTEINi technology for drug discovery programs.
Digitalizing Communications in an age of Remote Learning Random42 Scientific Communication 2020-04-13 | In light of the rapid developments regarding the recent coronavirus outbreak, we are seeing its impact across numerous industries worldwide, including pharmaceuticals and biotechnology. It is becoming increasingly apparent that businesses need to adapt to flexible ways of working and new ways of marketing their products.COVID-19 has led to the cancellation of many conferences and congresses, meaning alternative approaches are required to connect with Health Care Professionals (HCPs) and other influential target audiences. Now is the time for pharmaceutical companies to completely digitalize their approach to product marketing, facilitating connections to HCPs without a conference booth or in-person representative. Random42 create high-quality digital content in the form of medical animation (MoA/MoD) and interactive experiences, explaining the science behind a product. These digital assets can be leveraged across various remote learning applications.These ongoing digital changes will facilitate remote learning for our clients, meaning effective communication without a physical presence. Random42 is the global leader in medical animation and scientific storytelling. Get in touch now to discuss digitalizing your marketing approach to facilitate remote learning across your campaign. Please contact us at info@random42.com
Organ on Chip Animation | Multi-Electrode Array Chip Technology Random42 Scientific Communication 2020-04-09 | Imec’s multi-electrode array chip has been developed to fulfil the need for cell-interfacing tools that have better predictive power of the human physiology. It can perform multiple tests in parallel helping drug discovery programmes better understand diseases and develop more efficient drugs and therapies faster.The mechanism of action (MoA) animation takes you on a journey inside the device, showing how the micro-sized electrodes on the chip can be used to precisely reprogram cells to grow complex tissue models. It reveals how tissue models on the multi-electrode array chips can very closely mimic the properties of the actual organ, and how this has potential for personalised drug screening, for disease modelling, and patient-derived cell-based therapies.The animation appears on Imec’s micro-electrode array page, showcasing how Imec use the power of nano-electronics to develop ground-breaking tools for drug development.
Blood Volume Monitoring Animation - Crit-Line® Technology Random42 Scientific Communication 2020-04-09 | Crit-Line® technology is the latest innovation in blood volume monitoring and provides real-time clinically relevant parameters that help clinicians to optimize fluid removal, maximize ultrafiltration, and reduce the risk of intra-dialytic symptoms in dialysis patients.The Mechanism of Action (MoA) animation for the technology platform allows the audience to gain an insight into the challenges associated with fluid overload in the end-stage renal disease population and the benefit of Crit-Line® profiles, to gain insight on your patient’s tolerance to the ultrafiltration goal.The assets for the animation were also used to create an interactive application for mobile and interactive touchscreen experience.
Cardiovascular Animation - Autonomic Regulation Therapy Random42 Scientific Communication 2020-04-09 | The LivaNova VITARIA System is currently being evaluated in patients with continued heart failure after therapy. It is designed to deliver Autonomic Regulation Therapy (ART) through electrical stimulation of the vagus nerve.This animation highlights how ART can restore balance within the cardiac nervous system to treat chronic heart failure. It has been developed in three sections; the first introducing the cardiovascular system and its control by the autonomic nervous system (ANS), the second showing the development of cardiac disease and its effects on ANS function, and the final showing how the VITARIA System utilises ART to restore ANS function and stop the progression of cardiovascular disease and the resulting heart failure. The three-step-approach allows the science behind the LivaNova VITARIA System to come across in a way that is clear and easily understood.
Phospholipid Drug Conjugate MoA Animation Random42 Scientific Communication 2020-04-09 | Cellectar’s Phospholipid Drug Conjugate Candidate platform provides selective delivery of a diverse range of oncologic warheads to cancerous cells of varied origin. We developed a Mechanism of Action (MoA) animation that Cellectar utilize to drive traffic to their website, for investor relations and their clinical trial sites. In May 2019 the company website attracted 13,000 visitors, with over a third visiting the MoA page. The animation has also been a useful asset for their social media activities, featuring in the most liked and shared posts to date.
Immunotherapy Animation - Batu Biologics’ ValloVax™ Technology Random42 Scientific Communication 2020-04-08 | Batu Biologics’ ValloVax™ technology stimulates the immune system to target multiple apoptotic pathways, slowing the angiogenic process within cancer. The proprietary immunotherapy aims to starve the tumour by training your immune system to target tumour-associated blood vessels. The Mechanism of Action (MoA) animation was created to highlight this less toxic and more effective therapeutic option for the treatment of cancer.Batu have fully utilized the visual toolkits we provide to solidify their brand identity across multiple platforms. The full animation is the main feature of their website homepage, bringing their science to life.Several shorter clips of animation reside within their corporate introductory video and within the Batu blog series on YouTube named ‘Starve the Tumor’. Stills from the animation also serve as the backdrop for key website pages such as their therapeutic pipeline, unifying the brand throughout.
NEW - Devices and Diagnostics Animation Showreel Random42 Scientific Communication 2020-04-02 | With our medical device animations, we can take the viewer on a unique journey visually explaining the science behind various medical devices and/or machinery, right down to the molecular level of diagnostic techniques.We transform complicated science into concise documentaries and digital solutions to clearly articulate core messages behind pharmaceutical and medical products, devices, and diagnostic tests. Every project is designed to enable clients to relay complex scientific information into a deliverable that elevates a product or disease area to a new level of understanding.Find out more: random42.com/medical-device-animation
Animal Health Animation - Canine Allergy Random42 Scientific Communication 2020-04-01 | Zoetis’ APOQUEL is the first medicine designed to target the itch and inflammation associated with canine allergic conditions such as flea allergy or contact allergy. It works by selectively inhibiting the pathways involved in sending itch signals to the brain, significantly reducing itching behaviour in affected dogs within 24 hours of treatment. It also blocks the signals involved in inflammation in the skin of the dog, resulting in decreased redness and itching.We created a mechanism of action (MoA) animation showing the effects of APOQUEL on canine allergic itch and inflammation at a molecular level. This demonstrates how APOQUEL works differently to steroids, thus preventing the side effects associated with steroids and improving the quality of life of the affected dog.The animation appears on the Zoetis APOQUEL product page where it is used to educate animal health care providers about the benefits of treating canine allergic itch and inflammation with APOQUEL.
