Dr Massimo Mantegazza talks about his epilepsy electrophysiology research Scientifica 2026-09-20 | Dr Massimo Mantegazza talks about his epilepsy electrophysiology research
Mental Health Awareness Week Scientifica 2023-05-18 | To support this year’s Mental Health Awareness Week, we took on the challenge of completing 365 miles to promote the positive effects that exercise has on managing your anxiety and overall mental health. #milesforourmindsSee how we did....
A guide to Differential Interference Contrast (DIC) Scientifica 2023-05-09 | Join Geoff Ingram, Senior Product Specialist at Scientifica, as he explains what DIC is, how does it work and how to set it up on an upright microscope like the Scientifica SliceScope.
Scientifica VistaScope at Schroder Lab, University of Sussex Scientifica 2023-01-30 | Uncover how our latest multiphoton system, the VistaScope, has been helping Dr Sylvia Schröder and her team to understand how behaviour influences visual processing in the early visual system, including the retina and the superior colliculus.
PatchScope Pro 介绍说明 Scientifica 2022-11-29 | Matt Kemp, Managing Director of Scientifica introduces the PatchScope Pro range – fully integrated electrophysiology rigs built for patching in single cells, cultures or cell monolayers.
Neuroscience 2022 Scientifica 2022-11-22 | The 2022 annual Neuroscience meeting brought 24,351 people across 72 countries together to celebrate the latest neuroscience research and technology. Check out what we got up to during our time at #sfn2022.
PatchScope Pro Systems Scientifica 2022-11-14 | The perfect patch clamp rigs for cultured cell electrophysiology. Designed by electrophysiologists, for electrophysiologists.
The first integrated solution for patching in cultured cells Scientifica 2022-11-14 | We continue to develop our globally recognised portfolio with the PatchScope Pro range – These are fully integrated electrophysiology rigs built for patching in single cells, cultures or cell monolayers.
Launching 14.11.2022 Scientifica 2022-10-25 | Adding to our trusted and modular portfolio of electrophysiology solutions...
Something is coming soon... Scientifica 2022-10-25 | Designed by electrophysiologists, for electrophysiologists.
Scientifica VistaScope: The premier solution for multiphoton imaging Scientifica 2022-08-09 | The premier solution for multiphoton imaging, with the largest-in-class field of view, allowing you to see more cells, more clearly than ever before.Use the VistaScope’s two identical scan paths to combine photostimulation and imaging, independent of wavelength. With an impressive 40mm field number, the VistaScope boasts multiphoton micro- and meso-scale imaging capabilities, at a microscope price tag.
Data captured at the Thibault Lab using the Scientifica HyperScope Scientifica 2022-07-29 | This video shows layer 2/3 somatosensory neurons flickering (GCaMP8f) in response to movement while the animal is ambulating. This data was captured by the Thibault Lab, University of Kentucky, using the Scientifica HyperScope.
Watch on-demand: Introduction to multicell patch clamp electrophysiology recordings Scientifica 2022-06-23 | In this webinar Dr Max Oginsky, Product Specialist at Scientifica, provided a comprehensive introduction to multicell patch clamp electrophysiology recordings.As part of this webinar, we welcomed keynote speaker, Dr. Stephanie C. Seeman, of the Allen Institute, who spoke about her exciting work and how multicell patch-clamp electrophysiology has benefitted her research.
An introduction to in vivo multiphoton microscopy Scientifica 2022-06-20 | In this webinar, Dr Zhongmin Lu, Asia-Pacific Product Specialist at Scientifica, provides a comprehensive introduction to in vivo multiphoton microscopy.
Top tips for presenting your scientific poster Scientifica 2022-06-10 | In this webinar, Scientifica's EMEIA Sales Manager, Dr Phillipa Timmins, shares her top tips for presenting your scientific poster.
Scientificas Ultra Super Deluxe Platinum Exclusive Experience Package Scientifica 2022-04-01 | At Scientifica, we push boundaries to empower you to make scientific discoveries. To celebrate Queen Elizabeth’s II Platinum Jubilee, we have developed a limited-edition package - fit for royalty. Discover more...
Geoff Ingram presenting at the 5th Cerebellum Day in Bordeaux, France Scientifica 2022-03-23 | The 5th Cerebellum Day was held between 9 - 10 March 2022 in Bordeaux, France. Geoff Ingram, Senior Product Specialist, gave a short presentation on Scientifica.
SciCam Pro - The ideal camera for electrophysiology Scientifica 2022-02-14 | Built in collaboration with scientific camera experts QImaging, the SciCam Pro is specifically designed for use with electrophysiology setups.The fanless cooling system and built-in grounding point create zero vibration and electrical noise for careful electrode positioning and fine electrophysiological recordings.Learn more: http://www.scientifica.uk.com/products/scientifica-scicam-pro
Two-photon zebrafish brain volumetric recording Scientifica 2021-11-10 | Two-photon recording from a three week old zebrafish brain explant of the line Tg(elavl3:GCaMP6s-nuclear). Four consecutive planes (upper to lower ones from left to right) of a volumetric recording (8 planes in total) are shown where first Dm (amygdala homolog in zebrafish) then Dl (Hippocampus homolog in zebrafish) were electrically stimulated by a glass-electrode (indicated in the upper left corner). Data acquired by Anna Ostenrath and Ewelina Bartoszek, PhD Students in the lab of Professor Emre Yaksi, Kavli Institute, NTNU, using a Scientifica Multiphoton Imaging System.
Sneak Peak: Uncover Scientificas industry-leading development Scientifica 2021-11-03 | The premier solution for multiphoton imaging. Sign up to be the first to discover more in our launch webinar on 30th November 2021.scientifica.uk.com/research-news/product-launch-webinar-uncover-scientificas-industry-leading-development
Patching four cells under visual control Scientifica 2021-10-26 | The left-hand side shows the Dodt contrast image; the right side shows the simultaneous two-photon excited fluorescence. Initially, the pipettes are positioned above the slice. They are then sequentially brought into position in front of the respective target cell and a seal formed, working from the deepest to the shallowest cell. There are several things to take particular note of. First, changes to the pressure applied to the pipette tip can be seen as changes in the dye streaming out of the respective tip. Next, dimple formation can be observed in both images for each pipette, but it is most pronounced for the third cell. Finally, the break-in to achieve whole-cell configuration is marked by the target cell beginning to fill with dye.
Advancements in multielectrode recording techniques in neurophysiology: Wire probes to Neuropixels Scientifica 2021-08-13 | On Thursday 12th August, Scientifica hosted the 'Advancements in multielectrode recording techniques in neurophysiology: From wire probes to Neuropixels' webinar in partnership with the British Neuroscience Association (BNA).scientifica.uk.com/research-news/watch-on-demand-advancements-in-multielectrode-recording-techniques-in-neurophysiology
Fluorescence Lifetime Imaging – Another Dimension in Multiphoton Imaging Scientifica 2021-08-09 | On 7th July, Dr. Christian Wilms, Research & Development Manager, Scientifica, gave a talk at the Imperial Neurotechnology 2021 – Centre for Neurotech Annual Research Symposium.Talk AbstractCommonly, fluorescence microscopy uses the colour and intensity of fluorescence to generate images. A third parameter of fluorescence is less commonly used in imaging: the excited state lifetime of a fluorescent molecule (aka the fluorescence lifetime). Similar to colour, the fluorescence lifetime is an absolute value which is not influenced by properties of the measurement system or by local concentrations of the fluorescent dye. As a result, fluorescence lifetime imaging (FLIM) can provide quantitative insights into the physiology of live cells. In combination with two-photon excitation, it becomes a powerful tool for the quantitative study of cellular signalling in deep tissue. In this talk we provide an introduction to FLIM, including the required instrumentation as well as introducing some example data to demonstrate versatility and potential of the technology for neuroscience researchers.
Multiphoton imaging with next-generation indicators Scientifica 2021-07-05 | On Wednesday 30th June, Scientifica hosted its first webinar 'Multiphoton imaging with next-generation indicators' in partnership with the British Neuroscience Association (BNA) and Chromacity.scientifica.uk.com/research-news/watch-on-demand-multiphoton-imaging-with-next-generation-indicators-webinar
Introducing Imogen Scientifica 2021-04-01 | Following the launch of the HoloStim-3D, our industry-leading all-optical solution, we wanted to support the research community even more.After extensive market research and the increasing popularity of interactive voice assistants in homes across the globe, our team worked hard implementing the most complex machine learning technology into the HoloStim-3D.For automated experiments, simplified workflows and an assistant, look no further than Scientifica's HoloStim-3D and Imogen.#ImogenAndStimulatescientifica.uk.com/neurowire/introducing-imogen-built-into-the-holostim-3d-just-say-your-command-and-imogen-will-respond
Introducing the Scientifica HoloStim-3D Scientifica 2021-01-18 | Interrogate larger neural networks at higher resolution than ever before, with the world's highest performing multiphoton all-optical solution.The HoloStim-3D seamlessly integrates with the HyperScope, an award-winning multiphoton imaging system, to create an industry-leading spatial light modulator (SLM) system for all-optical interrogation of neural networks with previously unachievable performance.Find out more here: scientifica.uk.com/products/scientifica-holostim-3d
Announcing the winners of Scientificas FENS 2020 competition Scientifica 2020-07-02 | Thank you to everyone who entered our FENS 2020 registration competition, we received a vast number of entries and were very impressed with the high standard of answers. Our judging panel, Matt Kemp, Managing Director, Dr. Christian Wilms, Research and Development Manager and Alex Murray, Head of Engineering and R&D, reviewed the anonymised entries and we are delighted to announce the winners.scientifica.uk.com/research-news/announcing-the-winners-of-our-competition-to-win-free-registration-to-fens-2020
Introducing Scienkitica: Because who doesnt love kittens? Scientifica 2020-04-01 | After providing neuroscience research solutions for more than 20 years, we wanted to go one step further and help ease the stress of researchers. From extensive market research and environmental scanning, it was clear that the changing our branding was the best to starting point.scientifica.uk.com/neurowire/introducing-scienkitica-because-who-doesnt-love-kittens
Scientificas three photon satellite event 2019 Scientifica 2019-11-07 | Scientifica held another successful three-photon satellite event at the 2019 Society for Neuroscience conference. Here is the full video of the talks given during this event by Dr. Christian Wilms, Scientifica, Dr. Murat Yildirim, MIT Picower Institute and Dr. Jack Waters, the Allen Institute.scientifica.uk.com/learning-zone/scientificas-three-photon-satellite-event-2019
Scientifica Meets - Bente Jacobsen and Dr Srdjan Ostojic Scientifica 2019-10-09 | Scientifica met Bente Jacobsen and Dr. Srdjan Ostojic during the Interacting with Neural Circuits course. Bente and Srdjan both attend this course as instructors. scientifica.uk.com/neurowire/scientifica-meets-bente-jacobsen-and-dr-srdjan-ostojic
Scientifica Meets - Dr. Pedro Garcia da Silva Scientifica 2019-09-12 | Scientifica met Dr. Pedro Garcia da Silva, organiser of the Interacting with Neural Circuits Summer course at the Champalimuad Centre for the Unknown, Lisbon.
Scientifica Meets - Jordan Murray Scientifica 2019-05-15 | Scientifica met Jordan Murray during the Advanced Optical Microscopy for Cell Biology course at the Marine Biological Association, Plymouth. Jordan is a PhD student in the lab of Professor Gail McConnell at the University of Strathclyde, where he uses the mesolens to study population dynamics in streptomyces bacteria.
Scientifica meets Dmitri Yousef Yengej Scientifica 2019-04-30 | Scientifica met Dmitri Yousef Yengej during his PhD at the University of Amsterdam. Dmitri shares that during his PhD he used Scientifica's SliceScope Pro 6000 electrophysiology system to investigate the excitability of neurons, including how their intrinsic excitability can change and how this affects whole networks.
Scientifica meets Dr. Adam Packer, Oxford University Scientifica 2019-04-30 | Find out more about the Sculpted Light in the Brain conference, including which topics and techniques are covered and how to register to attend from Co-Organiser Dr. Adam Packer, University of Oxford in the video below.Visit our website for more information: scientifica.uk.com/sculpted-light-in-the-brain-2019-conference
Scientifica Meets - Alex Sossick Scientifica 2019-04-29 | Scientifica met Alex Sossick, organiser of the 10-day Practical Course on Advanced Optical Microscopy for Cell Biology at the Marine Biological Association in Plymouth.
Scientifica Meets - Nelda Antonovaite Scientifica 2019-04-16 | Scientifica met Nelda Antonovaite, a PhD student at Vrije University Amsterdam, who uses the PatchStar micromanipulator to study the mechanical properties of brain tissue. Nelda explains that she does this using a technique called ferrule-top dynamic indentation, and that this is now being used to study the structural changes that occur in the brain in neurodegenerative diseases. scientifica.uk.com/neurowire/scientifica-meets-nelda-antonovaite
Scientifica Meets - Dr Matthew Parsons Scientifica 2019-04-04 | Scientifica met Dr. Matthew Parsons during the installation of a HyperScope, the first multiphoton imaging system in Newfoundland and Labrador.scientifica.uk.com/neurowire/scientifica-meets-dr-matthew-parsons
Introducing Scientificas new premium skincare range... Scientifica 2019-04-01 | After developing a range of premium equipment for neuroscience research, we wanted to go the extra mile and provide our loyal customers with a new range of ground-breaking products.Find out more here: scientifica.uk.com/neurowire/introducing-scientificas-new-premium-skincare-range
Scientifica meets Dr. David Ogden & Prof. Colin Brownlee Scientifica 2019-03-20 | Scientifica met Dr. David Ogden and Prof. Colin Brownlee at the Microelectrode Techniques for Cell Physiology Workshop in Plymouth. David and Colin are organisers of this course and have been involved in it since it began.Here, they explain that the course includes electronics, voltage-clamp experiments and microscopy, along with new additions each year to keep the course up to date. Find out more about the course, the equipment and how you can apply. www.mba.ac.uk/Microelectrode-techniques-cell-physiology
#Womeninscience: Dr. Olga Skiteva Scientifica 2019-02-12 | Dr. Olga Skiteva is a Postdoctoral Researcher at the Karolinska Institutet, Olga explains that her goal is to become a Group Leader and that she believes that an equal number of men and women should work in science.scientifica.uk.com/neurowire/womeninscience-dr-olga-skiteva
#Womeninscience: Dr. Anja Godfrey Scientifica 2019-02-11 | Dr. Anja Godfrey works as a Customer Support Associate at Scientifica. Here, she explains why she chose a career in science, who her role models are and why she decided to pursue a career in industry.scientifica.uk.com/neurowire/womeninscience-dr-anja-godfrey
#Womeninscience: Dr. Tiffany Schmidt Scientifica 2019-02-11 | As part of our celebrating women in science campaign, we interviewed Dr. Tiffany Schmidt, an Assistant Professor in the Neurobiology Department at Northwestern University. Tiffany shares how she successfully progressed her career and became a Principal Investigator. She also talks about the importance of female role models and how she balances having a family and working in research as an Assistant Professor.scientifica.uk.com/neurowire/celebrating-women-in-science-dr-tiffany-schmidt
Scientifica Meets - Dr. Clémence Bernard and Thomas Shallcross Scientifica 2019-01-17 | Clémence and Tom are presidents of the NEUReka! seminar series, part of the Department of Developmental Neurobiology programme of external seminars at King’s College London.
Frontiers in Neurophotonics Summer School Scientifica 2019-01-17 | The Frontiers in Neurophotonics Summer School is an opportunity to meet fellow researchers and students from around the world and discover the latest advances in live cell optical imaging techniques. Scientifica support this course each year, through provision of equipment and technical experts. Watch the video to find out more about how the course could benefit you. Applications for the 2019 Summer School are now accepted, until the deadline on 1st March.scientifica.uk.com/research-news/find-out-more-about-the-frontiers-in-neurophotonics-summer-school
Three-photon presentation by Dr Jack Waters, the Allen Institute Scientifica 2019-01-03 | Scientifica held a successful three-photon satellite event during the Society for Neuroscience 2018 conference. Here is the full presentation by keynote speaker Dr. Jack Waters, Associate Investigator at the Allen Institute.
Scientifica Meets - Dr Joern Steinert Scientifica 2018-12-04 | Scientifica met Dr. Joern Steinert at the Microelectrode Techniques for Cell Physiology workshop in Plymouth.
Scientificas three-photon satellite event Scientifica 2018-11-22 | Scientifica held a three-photon satellite event during the Society for Neuroscience 2018 conference. The event was extremely successful, and included talks from Dr. Christian Wilms, Scientifica’s R&D Manager, Dr. Yoann Zaouter from Amplitude Systemes and Dr.Jack Waters, the Allen Institute.
