Iso-Seq Social Club, Vol. 3 - Single-cell Iso-Seq applications in cancer and neurological disorders @PacificBiosciences

Uploaded September 2023 | Updated September 2026, 34 minutes ago

This video includes the following talks:

Who needs more ACTB isoforms? Discover more from your single-cell Iso-Seq sample with CRISPR-Cas9 depletion - Jon Armstrong

When single-cell resolution isn’t enough: going beyond short reads with new approaches to uncover the roots of tumor heterogeneity - Antonio Fuentes-Fayos, PhD

Integrating single cell genotyping with transcriptomics to identify disease-involved brain cell types in pediatric epilepsy - Katie Miller, PhD

Single cells + single molecules = isoform biology - Jason Underwood, PhD

Iso-Seq Social Club, Vol. 3 - Single-cell Iso-Seq applications in cancer and neurological disorders

Advancing microbial genomics with PacBio HiFi reads

There’s HiFi for That: How Lili Milani & Melissa Nel Scale with PacBio HiFi

The Full-Length Transcriptomic Atlas of Human Colorectal Cancer from Single-Cell Isoform Sequencing

Uncovering microbiomes of the rice phyllosphere using long-read metagenomic sequencing

What are we missing? | Dr. Paul Kruszka from GeneDx

Why accurate long reads are essential for rare disease research

PacBio Vega: Benchtop HiFi Sequencer Demo (ASHG 2024)

Detecting cancer fusion transcripts in long-read RNA-Seq data with CTAT-LR-fusion

SPRQ Chemistry, Vega, and our latest breakthroughs. PacBio workshop part 2 at PAG 2025.

HiFi sequencing in biopharma: Insights from an expert panel

Detecting 5mC & 6mA methylation with PacBio