Artificial Brain Simulation - Thalamocortical System, 3.5 Billion Synapses, 16.7 Million Neurons Ivan Dimkovic 2012-12-27 | Download DigiCortex demo here: http://www.digicortex.netSpikeFun 0.90 simulation of the mammalian brain's thalamocortical system with 16.7 million neurons and approx. 3.5 billion synapses (modeled using Izhikevich phenomenological neuron model with multiple compartments). Total simulation memory usage is 350 GB. Network build-up took approx. 2 hours on dual-CPU 16 core Intel Xeon 2687W system running @3.1 GHz.Simulation models AMPA, NMDA and GABA synaptic receptor kinetics, depressing and facilitating synapses (including differential axonal signalling depending on the target post-synaptic type), myelinated and non-myelinated axons, axonal bifurcations as well as short term synaptic plasticity modeled with Tsodyks-Markram quantal model of synaptic transmission as well as long term synaptic plasticity which is modeled using phenomenological model of spike-timing dependent plasticity (STDP).Neurons are created using data gathered by analysis of cortical neurons located in the primary visual cortex of a cat (Binzegger et al., 2004). Axonal projections through white-matter are guided using Diffusion Spectrum Imaging (DSI) imaging of healthy human adults. Pyramidal axons bifurcate into multiple projections depending on the cell sub-type and project ipsilaterally or contralaterally to distant cortical zones / thalamus.All neurons have multiple compartments. Pyramidal neurons have basal dendritic sub-tree as well as apical tuft that bifurcates in at least two dendritic branches in the terminating cortical layer. Average number of synapses per neuron is ~210, ranging from ~80 for basket cells of cortical layer II to ~380 for the pyramidal cells of cortical layer V which project to layers V and VI, identified as p5(L5/6) in the simulation.During the simulation, multiple activity clusters could be observed. Simulated intracortical EEG near the end of the video shows desynchronized activity across different cortical regions.
DigiCortex Brain Waves - Screen Saver Video Ivan Dimkovic 2023-12-05 | 6 minutes of white matter brain activity simulated with DigiCortex 2.14 Simulator - multiple frequencies in Delta, Alpha and Gamma Bands are present. Only long-range axonal tracts are rendered, no neurons are visible in the video.Download DigiCortex here: digicortex.net/node/7Get Right Here Right Now by Fatboy Slim and over 1M + mainstream tracks here go.lickd.co/MusicLicense ID: 3eyQ3eWV2vD
Journey to the Center of the Brain Ivan Dimkovic 2023-06-07 | Props to the cameraman who shrunk himself to record this.Video is a recorded camera pass through a running brain simulation. ~8.2 Billion 3D points are used to render each video frame. Zoom level varies from the size of the whole brain, to sub-millimeter view of parts of individual nuclei of Thalamus.Get DigiCortex Engine (simulator shown in the video) here: digicortex.net/node/7Get Second Moon by William Orbit and over 1M + mainstream tracks here go.lickd.co/MusicLicense ID: 7royvKGdnvW lickd.lnk.to/HasXmwID!Ivan+Dimkovic
DigiCortex v2 Launch Video Ivan Dimkovic 2023-05-01 | After over 4 years, DigiCortex Brain Simulator v2 is released! This video shows some of the new features. Some features were previewed in the pre-release demo as well as here on YT, but the final v2 build packs more news, such as DXGI rendering backend and new GUI. Check it out! Grab it from here: http://www.digicortex.net/node/7Audio Track: Strange Planet by: Shpongle and Astrix
White Matter Ivan Dimkovic 2023-01-24 | DigiCortex v2.0 Preview: Rendering of the simulated brain white matter exhibiting slow-wave activity (delta frequency range, somewhat similar to deep sleep). Simulation includes 10 million axonal pathways and 4.1 Billion synapes. Rendered in full detail.Audio Copyright Information:Get Sun Makes Everything More Beautiful (Original Mix) by Harmonic Frequency and over 1M + mainstream tracks here go.lickd.co/MusicLicense ID: E7jw75r2jZD
Ghost in the Shell (Inside the Brain Simulation) Ivan Dimkovic 2022-09-01 | THis preview shows how to discover neuroanatomic structures by applying filtering by ROI, cell and axonal pathway. Additionally, "Brainbow-like" staining can be applied to distinguish individual cell populations better, including setting your own preferred color for each cell type. Rendered simulation uses biologically motivated models of neurons and synapses and also models signal propagation delays (that could be seen as 'stripes' in the video). Audio: Couture featuring Rachelle - Afterglow; Producer – Steve Anderson; Vocals – Rachelle; Written-By – Couture; Label: Audio Therapy
Phantoms in the Brain (4K UHD) Ivan Dimkovic 2022-08-23 | Or just... some chatting axons? Check out the sneak preview of "Neon Connectome" visualization engine showing how signals propagate through the (simulated) brain. Near the end of the video, we increase the contrast of electrical impulses flowing through the brain white matter making them look like sparks tracing loops as they zoom through associative and thalamocortical tracts creating the "remembered present".--Get Four3two (Original Mix) by Phaxe, Morten Granau here https://t.lickd.co/1a61f1ee2f59423c91f58af8471ce49dLicense ID: z38Pj6mmDAOGet this and other songs for your next YouTube video at lickd.co
DigiCortex v2 Feature Preview: Shadertoy (Long Version) Ivan Dimkovic 2022-08-05 | Super early preview of a live "Shadertoy" feature of DigiCortex v2Edit visualization shaders and compile/replace on the fly! Even GLSL editor is built in (not that anybody has to use it of course) Coming soon to fry CPUs and GPUs near you...
DigiCortex v2 Feature Preview: Shadertoy Ivan Dimkovic 2022-08-04 | Super early preview of a live "Shadertoy" feature of DigiCortex v2 - disregard the poor visualization, it is a debug build after all....Edit visualization shaders and compile/replace on the fly! Even GLSL editor is built in (not that anybody has to use it of course) Coming soon to fry CPUs and GPUs near you...
DigiCortex 2.0 Preview 2 - Imrpoved Neon Connectome Renderer (4K) Ivan Dimkovic 2022-08-01 | Please switch to 4K version for maximum details!- Phong shading- Order-Independent Transparency- Floating-point textures- Hardware video encoding support direct on GPU from render textures- Support for SMAA anti-aliasing (not used in video)2 Billion Vertices (using 33 GB of GPU memory)!
DigiCortex 2.0 Preview: Neon Connectome renderer burning through 1 BILLION VERTICES... each frame! Ivan Dimkovic 2022-07-27 | Sneak preview of DigiCortex 2.0 update, showing new visualization engine with more than 1 Billion vertices rendered each video frame! And this is done in parallel to the actual neural simulation. New GUI is also visible replacing old OS-based controls.Stay tuned for more updates!
[4K] DigiCortex Simulation: 16 Million Neurons, 3.7 Billion Synapses, Visual System Ivan Dimkovic 2018-11-20 | Download DigiCortex Demo here: http://www.digicortex.net/node/7Small demo of the DigiCortex Engine (www.digicortex.net) support for visual inputs. The video shows the output of the thalamocortical system (consisting of 16 million neurons with 4 billion synapses) coupled with early visual system (combined output of 'ON' and 'OFF' Retinal Ganglion Cells) when subjected to natural video signal.
16.7 Million Neurons, Visual System, High Quality Rendering Ivan Dimkovic 2018-11-06 | Download DigiCortex Demo here: http://www.digicortex.net/node/7Small demo of the DigiCortex Engine (www.digicortex.net) support for visual inputs. The video shows the output of the thalamocortical system (consisting of 16.7 million neurons with 4 billion synapses) coupled with early visual system (combined output of 'ON' and 'OFF' Retinal Ganglion Cells) when subjected to natural video signal. Number of primary visual cortex sensory neurons is around 400 thousand, processing visual signal coming from 153600 "ON" and "OFF" retinal ganglion cells (effective resolution: 320x240 pixels) and fed through 38400 "ON" and "OFF" thalamic relay cells (effective resolution: 160x120 pixels). Ratio of primary V1 sensory to thalamic LGN cells is approx. 10:1 (10 cortical Spiny Stellate and Pyramidal cells in layers 2/3 and 4 to one dLGN Thalamic Relay Cell).Rectangle on the bottom right side shows "live" activity of the Retinal Ganglion Cells (RGCs) which are fed with the natural video, each black dot represents the single action potential (spike) of the 'OFF' retinal ganglion cell. Each white dot represents the single spike of the 'ON' retinal ganglion cell. Gray areas are areas without neural activity in each video frame / simulation time=step.Prior to exciting retinal ganglion cells simulated by DigiCortex module (Izhikevich adaptive quadratic integrate and fire model), the input current from photo receptors was processed using Virtual Retina (www-sop.inria.fr/neuromathcomp/public/software/virtualretina/) model of Outer Plexiform Layer (OPL) and Inner Plexiform Layer (IPL).Signals from the spiking retinal ganglion cells are bound for lateral geniculate nucleus (LGN) of dorsal thalamus, where they are additionally filtered in temporal domain and then sent finally to the first cortical destination: primary visual cortex (V1). Following V1, signal spreads to higher cortical areas based on long-range brain connectivity collected in the Human Connectome Project (HCP).Neurons in the primary visual cortex exhibit strong activity in alpha, beta and gamma frequency ranges as it would be expected based on experimental observations. Alpha waves can be seen in the V1 area throughout the video.DIFFUSION MRI DATA SOURCE NOTICE:Diffusion MRI Data collection and sharing for this project was provided by the Human Connectome Project (HCP; Principal Investigators: Bruce Rosen, M.D., Ph.D., Arthur W. Toga, Ph.D., Van J. Weeden, MD). HCP funding was provided by the National Institute of Dental and Craniofacial Research (NIDCR), the National Institute of Mental Health (NIMH), and the National Institute of Neurological Disorders and Stroke (NINDS). HCP data are disseminated by the Laboratory of Neuro Imaging at the University of California, Los Angeles.
DigiCortex Artificial Retina + Brain Simulation: 4 Billion Synapses, 16.7 Million Neurons Ivan Dimkovic 2014-04-23 | Download DigiCortex Demo here: http://www.digicortex.net/node/7Small demo of the DigiCortex Engine (www.digicortex.net) support for visual inputs. The video shows the output of the thalamocortical system (consisting of 16.7 million neurons with 4 billion synapses) coupled with early visual system (combined output of 'ON' and 'OFF' Retinal Ganglion Cells) when subjected to natural video signal. Number of primary visual cortex sensory neurons is around 400 thousand, processing visual signal coming from 153600 "ON" and "OFF" retinal ganglion cells (effective resolution: 320x240 pixels) and fed through 38400 "ON" and "OFF" thalamic relay cells (effective resolution: 160x120 pixels). Ratio of primary V1 sensory to thalamic LGN cells is approx. 10:1 (10 cortical Spiny Stellate and Pyramidal cells in layers 2/3 and 4 to one dLGN Thalamic Relay Cell).Rectangle on the bottom right side shows "live" activity of the Retinal Ganglion Cells (RGCs) which are fed with the natural video, each black dot represents the single action potential (spike) of the 'OFF' retinal ganglion cell. Each white dot represents the single spike of the 'ON' retinal ganglion cell. Gray areas are areas without neural activity in each video frame / simulation time=step.Prior to exciting retinal ganglion cells simulated by DigiCortex module (Izhikevich adaptive quadratic integrate and fire model), the input current from photo receptors was processed using Virtual Retina (www-sop.inria.fr/neuromathcomp/public/software/virtualretina/) model of Outer Plexiform Layer (OPL) and Inner Plexiform Layer (IPL).Signals from the spiking retinal ganglion cells are bound for lateral geniculate nucleus (LGN) of dorsal thalamus, where they are additionally filtered in temporal domain and then sent finally to the first cortical destination: primary visual cortex (V1). Following V1, signal spreads to higher cortical areas based on long-range brain connectivity collected in the Human Connectome Project (HCP).Neurons in the primary visual cortex exhibit strong activity in alpha, beta and gamma frequency ranges as it would be expected based on experimental observations. Alpha waves can be seen in the V1 area throughout the video.DIFFUSION MRI DATA SOURCE NOTICE:Diffusion MRI Data collection and sharing for this project was provided by the Human Connectome Project (HCP; Principal Investigators: Bruce Rosen, M.D., Ph.D., Arthur W. Toga, Ph.D., Van J. Weeden, MD). HCP funding was provided by the National Institute of Dental and Craniofacial Research (NIDCR), the National Institute of Mental Health (NIMH), and the National Institute of Neurological Disorders and Stroke (NINDS). HCP data are disseminated by the Laboratory of Neuro Imaging at the University of California, Los Angeles.
DigiCortex Artificial Brain Simulation - Retina + 8 Million Cortical Neurons / 2 Billion Synapses Ivan Dimkovic 2013-06-30 | Download DigiCortex Demo here: http://www.digicortex.net/node/7Small demo of the DigiCortex Engine (www.digicortex.net) support for visual inputs. The video shows the output of the thalamocortical system (consisting of 8 million neurons with 2 billion synapses) coupled with early visual system (combined output of 'ON' and 'OFF' Retinal Ganglion Cells) when subjected to natural video signal.Rectangle on the right side shows activity of the Retinal Ganglion Cells (RGCs), each black dot represents the single action potential (spike) of the 'OFF' retinal ganglion cell. Each white dot represents the single spike of the 'ON' retinal ganglion cell. Gray areas are areas without neural activity in each video frame / simulation time=step.Prior to exciting retinal ganglion cells simulated by DigiCortex module (Izhikevich adaptive quadratic integrate and fire model), the input current from photo receptors was processed using Virtual Retina (www-sop.inria.fr/neuromathcomp/public/software/virtualretina/) model of Outer Plexiform Layer (OPL) and Inner Plexiform Layer (IPL).Signals from the spiking retinal ganglion cells are bound for lateral geniculate nucleus (LGN) of dorsal thalamus, where they are additionally filtered in temporal domain and sent finally to primary visual cortex (V1).Neurons in the primary visual cortex exhibit strong activity in alpha, beta and gamma frequency ranges as it would be expected based on experimental observations.
DigiCortex Cat Retina Amsterdam Live Demo Ivan Dimkovic 2013-06-21 | Download DigiCortex Demo here: http://www.digicortex.net/node/7In this video, we show a simulation of a cat thalamocortical system (downscaled to run on the notebook). The "cat brain" is fed with the visual sensory signal coming from INRIA's Virtual Retina module that emulates cat's X retinal cells (Wohrer 2008). It is relayed to cat's visual cortex through thalamic relay cells (middle of the brain, blue color) where it activates cortical network. The top left window shows how the cat's retinal cells react on moving objects. The main window of the DigiCortex shows how cat's brain reacts to this visual input. The two intense blue-colored regions of the brain are thalamic relay cells which relay the visual input signal to the rest of the brain (i.e., the primary visual cortex). The little bright spikes of activity popping up in the video represent the activity of individual neurons reacting to the changes on the street. See how the simulated brain reacts strongly to moving objects in the video signal!
DigiCortex Artificial Brain Simulation - Retina Module Demonstration Ivan Dimkovic 2013-04-27 | Download DigiCortex Demo here: http://www.digicortex.net/node/7Small demo of the DigiCortex Engine (www.digicortex.net) support for visual inputs. The video shows the output of the early visual system (combined output of 'ON' and 'OFF' Retinal Ganglion Cells) when subjected to natural video input as well as the response of the cells in the primary visual cortex (V1). In the retina window (small), each black dot represents the single action potential (spike) of the 'OFF' retinal ganglion cell. Each white dot represents the single spike of the 'ON' retinal ganglion cell. Gray areas are areas without neural activity in each video frame / simulation time=step.Prior to exciting retinal ganglion cells simulated by DigiCortex module (Izhikevich adaptive quadratic integrate and fire model), the input current from photo receptors was processed using Virtual Retina (http://www-sop.inria.fr/neuromathcomp...) model of Outer Plexiform Layer (OPL) and Inner Plexiform Layer (IPL).Signals from the spiking retinal ganglion cells are bound for lateral geniculate nucleus (LGN) of dorsal thalamus, where they are additionally filtered in temporal domain and sent finally to primary visual cortex (V1).
DigiCortex Artificial Brain Simulation - Upcoming (v0.96) Retina Module Ivan Dimkovic 2013-04-26 | Sneak preview of the DigiCortex (www.digicortex.net) support for visual inputs. The video shows the output of the early visual system (combined output of 'ON' and 'OFF' Retinal Ganglion Cells) when subjected to natural video input. Each black dot represents the single action potential (spike) of the 'OFF' retinal ganglion cell. Each white dot represents the single spike of the 'ON' retinal ganglion cell. Gray areas are areas without neural activity in each video frame / simulation time=step.Prior to exciting retinal ganglion cells simulated by DigiCortex module (Izhikevich adaptive quadratic integrate and fire model), the input current from photo receptors was processed using Virtual Retina (http://www-sop.inria.fr/neuromathcomp/public/software/virtualretina/) model of Outer Plexiform Layer (OPL) and Inner Plexiform Layer (IPL).Signals from the spiking retinal ganglion cells are bound for lateral geniculate nucleus (LGN) of dorsal thalamus, where they are additionally filtered in temporal domain and sent finally to primary visual cortex (V1).
Artificial Brain Simulation - Thalamocortical System, 16.7 Million Neurons - 2.1 Billion Synapses Ivan Dimkovic 2012-12-12 | Download DigiCortex demo here: http://www.digicortex.netSimulation of the mammalian thalamocortical system with 16.7 million neurons (Izhikevich phenomenological neuron model, multiple compartments) with 2.1 billion synapses using SpikeFun demo simulator (v0.89) Simulation models AMPA, NMDA and GABA receptor kinetics, depressing and facilitating synapses, myelinated and non-myelinated axons, axonal bifurcations as well as short and long term synaptic plasticity (STDP) using phenomenological model of Markram et. al.Neurons are created using data gathered by analysis of cortical neurons located in the primary visual cortex of a cat (Binzegger et al., 2004). Axonal projections through white-matter are guided using Diffusion Spectrum Imaging (DSI) imaging of healthy human adults. Pyramidal axons bifurcate into multiple projections depending on the cell sub-type and project ipsilaterally or contralaterally to distant cortical zones / thalamus.
Artificial Brain Simulation - Ascending Reticular Activating System and Thalamocortical Networks Ivan Dimkovic 2012-10-01 | Download DigiCortex demo here: http://www.digicortex.netSimulation of the mammalian thalamocortical system with ascending activation from brainstem pedunculopontine tegmental nucleus (PPTN). Simulation has 1 million multi-compartmental neurons (Izhikevich phenomenological neuron model) with 180 million synapses using SpikeFun demo simulator (v0.82). Simulation models AMPA, NMDA and GABA receptor kinetics, myelinated and non-myelinated axons, axonal bifurcations as well as short and long term synaptic plasticity (STDP) using model of Markram et. al.Neurons are created using data gathered by analysis of cortical neurons located in the primary visual cortex of a cat (Binzegger et al., 2004). Axonal projections through white-matter are guided using Diffusion Spectrum Imaging (DSI) imaging of healthy human adults. Pyramidal axons bifurcate into multiple projections depending on the cell sub-type and project ipsilaterally or contralaterally to distant cortical zones / thalamus.
Artificial Brain Simulation - Thalamocortical System, 8 Million Neurons - 1.4 Billion Synapses Ivan Dimkovic 2012-05-30 | Download SpikeFun here: http://www.dimkovic.comSimulation of the mammal thalamocortical system with 8 million neurons (Izhikevich phenomenological neuron model, multiple compartments) with 1.4 billion synapses using SpikeFun demo simulator (v0.71) Simulation models AMPA, NMDA and GABA receptor kinetics, myelinated and non-myelinated axons, axonal bifurcations as well as short and long term synaptic plasticity (STDP) using model of Markram et. al.Neurons are created using data gathered by analysis of cortical neurons located in the primary visual cortex of a cat (Binzegger et al., 2004). Axonal projections through white-matter are guided using Diffusion Spectrum Imaging (DSI) imaging of healthy human adults. Pyramidal axons bifurcate into multiple projections depending on the cell sub-type and project ipsilaterally or contralaterally to distant cortical zones / thalamus.
Simulated Thalamocortical Brain Network 6 - 3D View, 3 Million Neurons, 476M Synapses Ivan Dimkovic 2012-05-08 | Download SpikeFun here: http://www.dimkovic.comSimulation of the mammal thalamocortical system with 3 million neurons (Izhikevich phenomenological neuron model, multiple compartments) with 476 million synapses using SpikeFun demo simulator (v0.67) Simulation models AMPA, NMDA and GABA receptor kinetics, myelinated and non-myelinated axons, axonal bifurcations as well as short and long term synaptic plasticity (STDP) using model of Markram et. al.Neurons are created using data gathered by analysis of cortical neurons located in the primary visual cortex of a cat (Binzegger et al., 2004). Axonal projections through white-matter are guided using Diffusion Spectrum Imaging (DSI) imaging of healthy human adults. Pyramidal axons bifurcate into multiple projections depending on the cell sub-type and project ipsilaterally or contralaterally to distant cortical zones / thalamus.
Simulated Thalamocortical Brain Network 5 - 3D View, 2 Million Neurons, 282M Synapses Ivan Dimkovic 2012-05-01 | Download SpikeFun here: http://www.dimkovic.comSimulation of the mammal thalamocortical system with 2 million neurons (Izhikevich phenomenological neuron model, multiple compartments) with 282 million synapses using SpikeFun demo simulator (v0.67) Simulation models AMPA, NMDA and GABA receptor kinetics, myelinated and non-myelinated axons, axonal bifurcations as well as short and long term synaptic plasticity (STDP) using model of Markram et. al.Neurons are created using data gathered by analysis of cortical neurons located in the primary visual cortex of a cat (Binzegger et al., 2004). Axonal projections through white-matter are guided using Diffusion Spectrum Imaging (DSI) imaging of healthy human adults. Pyramidal axons bifurcate into multiple projections depending on the cell sub-type and project ipsilaterally or contralaterally to distant cortical zones / thalamus.
Simulated Thalamocortical Brain Network 4 - 3D View, 2 Million Neurons, 282M Synapses Ivan Dimkovic 2012-05-01 | Download SpikeFun here: http://www.dimkovic.comSimulation of the mammal thalamocortical system with 2 million neurons (Izhikevich phenomenological neuron model, multiple compartments) with 282 million synapses using SpikeFun demo simulator (v0.67) Simulation models AMPA, NMDA and GABA receptor kinetics, myelinated and non-myelinated axons, axonal bifurcations as well as short and long term synaptic plasticity (STDP) using model of Markram et. al.Neurons are created using data gathered by analysis of cortical neurons located in the primary visual cortex of a cat (Binzegger et al., 2004). Axonal projections through white-matter are guided using Diffusion Spectrum Imaging (DSI) imaging of healthy human adults. Pyramidal axons bifurcate into multiple projections depending on the cell sub-type and project ipsilaterally or contralaterally to distant cortical zones / thalamus.
Simulation of Spiking Thalamocortical Brain Network 4 - 3D View, 1M Neurons, 189M Synapses Ivan Dimkovic 2012-04-22 | Download SpikeFun here: http://www.dimkovic.comSimulation of the mammal thalamocortical system with 1 million neurons (Izhikevich model, multiple compartments) with 189 million synapses using SpikeFun demo simulator (v0.66) Simulation models AMPA, NMDA and GABA receptor kinetics, myelinated and non-myelinated axons, axonal bifurcations as well as short and long term synaptic plasticity (STDP).Neurons are created using data gathered by analysis of cortical neurons located in the primary visual cortex of a cat (Binzegger et al., 2004). Axonal projections through white-matter are guided using Diffusion Spectrum Imaging (DSI) imaging of healthy human adults. Pyramidal axons bifurcate into multiple projections depending on the cell sub-type and project ipsilaterally or contralaterally to distant cortical zones / thalamus.
Simulation of Spiking Thalamocortical Brain Network 3 - 3D View, 1M Neurons, 189M Synapses Ivan Dimkovic 2012-04-22 | Download SpikeFun here: http://www.dimkovic.comSimulation of the mammal thalamocortical system with 1 million neurons (Izhikevich model, multiple compartments) with 189 million synapses using SpikeFun demo simulator (v0.66) Simulation models AMPA, NMDA and GABA receptor kinetics, myelinated and non-myelinated axons, axonal bifurcations as well as short and long term synaptic plasticity (STDP).Neurons are created using data gathered by analysis of cortical neurons located in the primary visual cortex of a cat (Binzegger et al., 2004). Axonal projections through white-matter are guided using Diffusion Spectrum Imaging (DSI) imaging of healthy human adults. Pyramidal axons bifurcate into multiple projections depending on the cell sub-type and project ipsilaterally or contralaterally to distant cortical zones / thalamus.
Thalamocortical Loops - Spiking Neural Network Simulation Ivan Dimkovic 2012-03-11 | Download SpikeFun here: http://www.dimkovic.comSimulation of the mammal thalamocortical system with 1.4 million neurons (Izhikevich model, multiple compartments) with 127 million synapses using SpikeFun demo simulator (v0.58) Video starts with the brief injection of depolarizing current into a thalamocortical relay cell that projects to cortex. Evoked response triggers prolonged reverberating activity of the entire thalamocortical system. Simulation models AMPA, NMDA and GABA receptor kinetics, myelinated and non-myelinated axons, axonal bifurcations as well as short and long term synaptic plasticity (STDP).Neurons are created using data gathered by analysis of cortical neurons located in the primary visual cortex of a cat (Binzegger et al., 2004). Axonal projections through white-matter are guided using Diffusion Spectrum Imaging (DSI) imaging of healthy human adults. Pyramidal axons bifurcate into multiple projections depending on the cell sub-type and project ipsilaterally or contralaterally to distant cortical zones / thalamus.
Simulation of Spiking Thalamocortical Brain Network 2 - 3D View, 1.4M Neurons, 140M Synapses Ivan Dimkovic 2012-03-04 | Download SpikeFun here: http://www.dimkovic.comSimulation of the mammal thalamocortical system with 1.4 million neurons (Izhikevich model, multiple compartments) with 143 million synapses using SpikeFun demo simulator (v0.57) Simulation models AMPA, NMDA and GABA receptor kinetics, myelinated and non-myelinated axons, axonal bifurcations as well as short and long term synaptic plasticity (STDP).Neurons are created using data gathered by analysis of cortical neurons located in the primary visual cortex of a cat (Binzegger et al., 2004). Axonal projections through white-matter are guided using Diffusion Spectrum Imaging (DSI) imaging of healthy human adults. Pyramidal axons bifurcate into multiple projections depending on the cell sub-type and project ipsilaterally or contralaterally to distant cortical zones / thalamus.
Simulation of Thalamocortical Brain Network - Spiking Neural Network, 1.4M Neurons, 140M Synapses Ivan Dimkovic 2012-03-04 | Download SpikeFun here: http://www.dimkovic.comSimulation of the mammal thalamocortical system with 1.4 million neurons (Izhikevich model, multiple compartments) with 143 million synapses using SpikeFun demo simulator (v0.57) Simulation models AMPA, NMDA and GABA receptor kinetics, myelinated and non-myelinated axons, axonal bifurcations as well as short and long term synaptic plasticity (STDP).Neurons are created using data gathered by analysis of cortical neurons located in the primary visual cortex of a cat (Binzegger et al., 2004). Axonal projections through white-matter are guided using Diffusion Spectrum Imaging (DSI) imaging of healthy human adults. Pyramidal axons bifurcate into multiple projections depending on the cell sub-type and project ipsilaterally or contralaterally to distant cortical zones / thalamus.
SpikeFun - Single Neuron Stimulation Impact on Simulated Brain Network Ivan Dimkovic 2012-02-27 | Spiny-Stellate Cell (Layer IV), located in the visual cortex, is briefly stimulated in the SpikeFun cortical simulation by injecting brief current pulse in the simulated neuron. Current injection triggers a spike in the stimulated neuron. Before the induced spike, complete cortical network is intentionally switched "off" so the propagation of the single neuron activation could be seen.As it could be seen from the video, as a result of the single-neuron stimulus different cortical areas are being activated - going as far as the frontal cortex.Even though it was triggered by a single neuron, activity persists for about 2 seconds after the induced spike. External stimulation is performed only once.Download SpikeFun: http://www.dimkovic.com
Thalamocortical System with SpikeFun - Spiking Neural Network, 1.2M Neurons, 151M Synapses Ivan Dimkovic 2012-01-08 | Download SpikeFun here: http://www.dimkovic.com Simulation of the mammal thalamocortical system with 1204224 neurons (Izhikevich model, multiple compartments) with 151.34 million synapses using SpikeFun demo simulator (v0.53) Simulation models AMPA, NMDA and GABA receptor kinetics, myelinated and non-myelinated axons, axonal bifurcations as well as short and long term synaptic plasticity (STDP). NOTE: In this version of SpikeFun white-matter guidance is not completed, so pyramidal neuron axons are bifurcating randomly to other cortical areas or thalamus (LII/III pyramidal neuron axons traverse through corpus callosum). Also, thalamus is modeled as a sphere (as it could be seen in the middle of fMRI simulation). fMRI BOLD simulation is sped-up 10x so changes could be seen in the video.
Spiking Neural Network Visualization with SpikeFun - 262000 neurons, 8M synapses Ivan Dimkovic 2011-10-09 | Simulation of 262144 neurons (Izhikevich model) with 8 million synapses done by SpikeFun demo simulator (v0.43) including AMPA, NMDA and GABA receptor kinetics, axonal propagation delay as well as short and long term synaptic plasticity.This video demonstrates network view (to enable network view start SpikeFun with /wireframe command line parameter)More details about SpikeFun: http://www.dimkovic.com
SpikeFun: Spiking Neural Network Visualization - Spherical Network Topology, Short Axons Ivan Dimkovic 2011-10-09 | Simulation of 262144 neurons with short axons (Izhikevich model) with 8 million synapses inside spherical topology, done by SpikeFun demo simulator (v0.43) including AMPA, NMDA and GABA receptor kinetics, axonal propagation delay as well as short and long term synaptic plasticity.This video demonstrates simulations with spherical network topology as well as "demo view" (available with the F11 key). Neuronal oscillations are exhibiting strong delta and alpha rhythms.More details about SpikeFun: http://www.dimkovic.com
SpikeFun: Spiking Neural Network Visualization - 260K neurons, 8M synapses Ivan Dimkovic 2011-10-01 | Simulation of 262144 neurons (Izhikevich model) with 8 million synapses done by SpikeFun demo simulator (v0.35) including AMPA, NMDA and GABA receptor kinetics, axonal propagation delay as well as short and long term synaptic plasticity.This video demonstrates network view (to enable network view start SpikeFun with /wireframe command line parameter)More details about SpikeFun: http://www.dimkovic.com
SpikeFun - Biological Neural Simulator 1536000 Neurons 46.5 Million Synapses Ivan Dimkovic 2011-09-25 | Simulation of 1536000 neurons (Izhikevich model) with 46.5 million synapses done by SpikeFun demo simulator (64-bit build) including AMPA, NMDA and GABA receptor kinetics, axonal propagation delay as well as short and long term synaptic plasticity. Simulation memory usage: 5.4 GB (simulation) + 281 MB (visualization) More details about SpikeFun: http://www.dimkovic.com
