Understanding Animal Research
How Psychedelics Really Alter The Brain!
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To learn more, watch the full video here: youtu.be/TAWmupsURCo
All video footage was filmed by the UAR in UK research facilities, licensed by the UK Home Office and regulated under the Animals (Scientific Procedures Act) 1986.
#animalresearch #amazinganimals #amazingscience #scienceshorts #lablife #science #rats
All video footage was filmed by the UAR in UK research facilities, licensed by the UK Home Office and regulated under the Animals (Scientific Procedures Act) 1986.
For more info: understandinganimalresearch.org.uk/news/the-science-behind-the-first-pig-to-human-lung-transplant
In the first of two of films, we discover how her pioneering new initiative, The 3Hs, is improving the lives of laboratory rodents in the lab. By addressing three core issues in husbandry - handling, housing and habituation - the program aims to reduce animal stress and increase their positive affective experiences. #animalresearch #animalscience #rat #mice #lablife #amazingscienceexperiment #scienceshorts
For more information, please visit our website: understandinganimalresearch.org.uk
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For more information on the 3H's initiative, see: 3hs-initiative.co.uk
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Did you know, 84% of the genes in zebrafish are associated with diseases in humans. This has allowed the fish to be used to study human and genetic disorders and diseases in greater detail.
All video footage was filmed by UAR in UK research facilities, licensed by the UK Home Office and regulated under the Animals (Scientific Procedures) Act 1986.
All video footage was filmed by UAR in UK research facilities, licensed by UK Home Office and regulated under the Animals (Scientific Procedures) Act 1986.
At the Francis Crick Institute, technicians make sure they're well cared for - from feeding and cleaning routines, to toys that keep them active and stimulated.
But that may be about to change.
Scientists in at The University of Sheffield have created a sensitive, cell-based assay that could replace animals entirely in these tests.
🔗 Read more: understandinganimalresearch.org.uk/news/replacing-animals-with-human-cell-cultures-in-pharmaceutical-toxin-safety-tests
#AnimalResearch #AnimalTesting #3Rs #medicalresearch
Spider Venoms contain unique molecules that can be used to develop new medicines. But how are the spiders used in research kept safe and comfortable?
This week, we're back at the Babraham Institute, as the technicians show us how they carry out their bird health checks. At the Avian Research Facility at The Pirbright Institute, poultry are kept for viral research purposes.
All video footage was filmed in UK research facilities, licensed by the UK Home Office and regulated under the Animals (Scientific Procedures) Act 1986.
Watch more videos on animal research at www.uar.org.uk/resources or www.youtube.com/@understandinganimalresearch
#AnimalResearch #AnimalTesting #LabLife #ScientificResearch
In this short video, we look at how birds are cared for at the Avian Research Facility at The Pirbright Institute, as one of their technicians describes the enrichment that they use for the birds. In this centre, poultry are kept for viral research purposes.
All video footage was filmed in UK research facilities, licensed by the UK Home Office and regulated under the Animals (Scientific Procedures) Act 1986.
Watch more videos on animal research at www.uar.org.uk/resources or www.youtube.com/@understandinganimalresearch
#AnimalResearch #AnimalTesting #LabLife #ScientificResearch
Scientific research using animals is vital to our continued and improved understanding of human and animal health. Animals are used to help us understand living organisms, study disease, and develop and test new medical treatments.
Animal research is also used to keep people, animals and the environment safe from new medicines and chemicals. Animal research is heavily regulated in the UK and can only take place with permission from the Home Office and when there is no other way to do the research.
New methods of research are constantly in development including non-animal methods such as organs on a chip, cell cultures, and computer models. However, at this time there is no method, singular or combined, which is capable of recreating the complexity of a whole living body.
For more information, visit our website:
understandinganimalresearch.org.uk
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understandinganimalresearch.org.uk/the-biomedical-animal-research-news-digest
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Zebrafish are the second most used animal in medical research. We share many genetic similarities with zebrafish which makes them ideal for researching genetic diseases. Also, zebrafish have a short lifespan and reproduce quickly which is a big plus when it comes to scientific research because we want to be able to create new medicines and learn about disease as quickly as possible, so that we can save lives.
All video footage was filmed in UK research facilities, licensed by the UK Home Office and regulated under the Animals (Scientific Procedures) Act 1986.
Watch more videos on animal research at www.uar.org.uk/resources or www.youtube.com/@understandinganimalresearch
#AnimalResearch #AnimalTesting #LabLife #ScientificResearch
Monitoring the health and welfare of animals is the main role of animal technicians in the lab. Here, an animal carer from The Babraham Institute shows us how to carry out a thorough health check for mice.
All video footage was filmed in UK research facilities, licensed by the UK Home Office and regulated under the Animals (Scientific Procedures) Act 1986.
Watch more videos on animal research at www.uar.org.uk/resources or www.youtube.com/@understandinganimalresearch
#AnimalResearch #AnimalTesting #LabLife #ScientificResearch
Currently, we have over 160 supporters drawn from various sectors including academic, pharmaceutical, charities, research funders, and professional and learned societies. In this video, Chief Executive Wendy Jarrett explains how we work with our various members across the country.
For more information, visit our website:
understandinganimalresearch.org.uk
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For more information, visit our website:
understandinganimalresearch.org.uk
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Dogs are rarely used in scientific research, with only 0.73% of experiments in the UK involving dogs in 2023. Like all animal species, dogs are only used in research when there is no alternative.
All video footage was filmed by UAR in UK research facilities, licensed by the UK Home Office and regulated under the Animals (Scientific Procedures) Act 1986.
Watch more videos on animal research (and dogs) at www.uar.org.uk/resources or www.youtube.com/@understandinganimalresearch
#AnimalResearch #AnimalTesting #LabLife #ScientificResearch
Today, we peek into the enclosure of the weird and wonderful naked mole rat at The University of Cambridge. Remarkably, these wrinkly little rodents are resistant to cancer!
All video footage was filmed by UAR in UK research facilities, licensed by the UK Home Office and regulated under the Animals (Scientific Procedures) Act 1986.
Watch more videos on animal research at www.uar.org.uk/resources or www.youtube.com/@understandinganimalresearch
#AnimalResearch #AnimalTesting #LabLife #ScientificResearch #MoleRat #NakedMoleRat #Rat
All video footage was filmed by UAR in UK research facilities, licensed by the UK Home Office and regulated under the Animals (Scientific Procedures) Act 1986.
Watch more videos on animal research at www.uar.org.uk/resources or www.youtube.com/@understandinganimalresearch
#AnimalResearch #AnimalTesting #LabLife #ScientificResearch #Xenopus #Frog
Our new series features short clips of real laboratory animals which we have filmed in facilities across the UK. Starting with a a quick peek into the world of guinea pigs at @ImperialCollege London.
All video footage was filmed by UAR in UK research facilities, licensed by the UK Home Office and regulated under the Animals (Scientific Procedures) Act 1986.
Watch more videos on animal research at www.uar.org.uk/resources or www.youtube.com/@understandinganimalresearch
#AnimalResearch #AnimalTesting #LabLife #GuineaPig #ScientificResearch
🐁 In 2014, the Concordat on Openness on Animal Research was launched. The Concordat is a public declaration by organisations carrying out animal research that they will be open about their work.
🐁 Concordat signatories provide information on their websites about their research in animals, and many of them also publish statistics on how many animals are used in their facilities each year.
🐁 Many signatories also use their websites and social media to share articles, photos, and videos of animal research. Signatories also work with us at UAR to produce informative content around the subject, for example, through Instagram Takeovers (available in our highlights).
For more information see
www.uar.org.uk
www.concordatopenness.org.uk
The correct answer is false, animal studies are usually 4x more expensive than non-animal methods. Watch this video to find out more.
Last week more than 300 people voted across our social media channels, the correct answer is 2 different species. Watch this short video to find out more.
The correct answer is true. Watch this short video to find out more.
The correct answer is false, the first animal to be cloned was in fact a tadpole in the 1950s. Find out more in this short video⬇️
The correct answer is chickens. Find out the results in this short video⬇️
Which European country is the largest user of research animals?
The correct answer is France.
Watch this short video to find out more.
The inaugural Professor Sir Colin Blakemore Memorial Award was presented by Sally Robinson, AWERB Chair at Cancer Research UK’s Manchester Institute and the University of Bristol, to Professor Emma Robinson. At a time when the use of animals at Bristol University was under scrutiny following campaign activity, Emma was adamant that being open had never been more important and so gave a high-profile evening lecture at the Bristol Neuroscience Festival, where she engaged with the public as she talked about the use of animals in research aiming to understand and treat mental health disorders.
The first Openness award was presented by Professor Robin Lovell-Badge, head of the Laboratory of Stem Cell Biology and Developmental Genetics at the Francis Crick Institute, to MRC Laboratory of Molecular Biology for their contributions to public engagement with a series of well-received events including a lab-wide open day and a friends-and-family BBQ.
The second Openness award was presented by Val Summers, Manager Regulatory Affairs & Home Office Liaison at Inotiv, to the University of Manchester for hosting a debate titled “Culture of care or culture of concern, let’s debate animal research”.
The Association of Medical Research Charities (AMRC) was highly commended for creating a sector-leading, comprehensive, accessible guide on funding and communicating about research involving
animals.
To read the full article, visit the link below:
understandinganimalresearch.org.uk/news/openness-awards-and-paget-lecture-2024
For more information about the 2024 Paget lecturer Professor Robin Lovell-Badge:
understandinganimalresearch.org.uk/news/introducing-the-2024-paget-lecture-by-robin-lovell-badge
For more information, visit our website:
understandinganimalresearch.org.uk
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This year, Professor Robin Lovell-Badge presented the 87th Paget Lecture, with his talk "Navigating the complexities of working with and talking about animals in research".
Robin Lovell-Badge obtained his PhD at University College London in 1978 and was a postdoc in Cambridge, both with Martin Evans. After an EMBO fellowship in Paris he established his independent laboratory in 1982 at the MRC Mammalian Development Unit, UCL, directed by Anne McLaren. In 1988 he moved to the MRC National Institute for Medical Research, which was incorporated into the Francis Crick Institute in 2015. In 1990, his lab discovered SRY, the Y-linked sex-determining gene and the SOX gene family. Major themes of his past and current work include sex determination, development of the gonads, nervous system and pituitary, and the biology of stem cells within these systems. He is also very active in both public engagement and policy work, notably around stem cells, genetics, human embryo and animal research, and in the ways science is regulated and disseminated.
Chapters:
01:58 Introduction
04:34 Stem cell research
06:55 Sex determination and differentiation
13:44 Sex determination history
16:45 Sry and sex determination
19:48 Sox9 and testis development
25:50 Foxl2 gene
32:18 Usp7 gene
33:13 In vitro cellular reprogramming
36:39 Conclusions
36:52 Openness
38:45 Human Fertilisation and Embryology bill 2008
43:17 Academy of Medical Sciences Report (ACHM 2011)
44:27 Public dialogue and policy
45:20 Openness in science
46:45 Questions from the audience
For more information, visit our website:
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For more information on Professor Robin Lovell-Badge:
crick.ac.uk/research/find-a-researcher/robin-lovell-badge
Read our animal research daily news feed (BARN):
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Please visit our YouTube channel for the full length version.
For more information, visit our website:
understandinganimalresearch.org.uk
For more top stories from 2024, read the full article on our website:
understandinganimalresearch.org.uk/news/the-biggest-animal-research-breakthroughs-in-2024-from-uar-members
Credits
Epilepsy device image from BBC News & UCL CADET Project
Fruit fly brain connectome images from MRC Laboratory of Molecular Biology
Lasker award videos from The Lasker Foundation
Chapters:
00:16 Epilepsy device
01:36 The most complex brain to ever be mapped
02:52 The new COPD treatment
03:55 Obesity drugs
04:59 Stem-cell therapy to restore vision
05:49 The new technique for assessing fertility hormone testing
For more information, visit our website:
understandinganimalresearch.org.uk
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Credits
Epilepsy device image from BBC News & UCL CADET Project
Fruit fly brain connectome images from MRC Laboratory of Molecular Biology
Lasker award videos from The Lasker Foundation
Dr Francesco Nevelli image from the NC3Rs
Thank you to everyone who attended our 11th Annual Openness Awards ceremony and 87th Stephen Paget Memorial Lecture, and to all of the award winners for their incredible work in animal research transparency.
For more information, visit our website:
understandinganimalresearch.org.uk
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The development of artificial blood vessels could majorly improve outcomes for heart bypass patients in the future.
Heart and circulatory diseases cause approximately 27% of all deaths in the UK and around 170,000 deaths each year (The British Heart Foundation).
For more information, please visit our website.
To stay updated on the latest animal research news, subscribe to our newsletter: https://www.understandinganimalresear...
For more information on animal research at the University of Edinburgh:
ed.ac.uk/research-innovation/animal-research
For more information on Dr Norbert Radacsi:
eng.ed.ac.uk/about/people/dr-norbert-radacsi
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The immersive exhibit is full of great research explaining all that we know about the brain, including some of the animal research that has led to important understandings of the brain. There are also brain models of various animals showing how brain size and shape varies between species.
Don't miss out on this great free exhibit!
This year's nominations include: MRC Laboratory of Molecular Biology, The Association of Medical Research Charities, The Francis Crick Institute, University of Hertfordshire, Swansea University, Imperial College London, University of Manchester and University of Glasgow.
Watch our short video below to find out more, and stay tuned for the awards ceremony on Monday 2 December 2024.
https://www.understandinganimalresear...
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#AnimalResearch #ConcordatOpenness
False. 90% of drugs tested on animals fail to make it to market, but this does not mean that animals research is a failure.
Watch this short video to find out more.
91% of you voted false.
While animal models are not a perfect representation of humans, they are statistically effective at predicting safety in humans and currently play an indispensable role in human and veterinary health and medicine.
This week we asked you, “True or false: Animals used in research have dedicated staff to care for them.”
The results are in. Watch this short reel to find out.
In this short documentary, and in collaboration with King's College London, Understanding Animal Research explores one of the alternative models being developed in cancer research.
Professor Tim Witney explains how his team is trying to reduce the number of mice used in science and medical research when imaging cancer, by using chicken eggs.
For more information, please visit our website.
To stay updated on the latest animal research news, subscribe to our newsletter: https://www.understandinganimalresear...
For more information on animal research at King's College London:
kcl.ac.uk/biological-sciences
For more information on Tim Witney:
kcl.ac.uk/people/tim-witney-1
Latest research from the Witney lab:
kcl.ac.uk/news/groundbreaking-cancer-imaging-trial-begins-using-advanced-pet-scanner
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Graphic created with BioRender.com.
We asked, “True or False: All animal experimentation can be replaced with alternative methods.”
How many of you were correct?
Watch this short video to find out!
This is a common concern raised by the public regarding the use of animals in biomedical and life sciences research.
The correct answer?
Watch this short video to find out the truth behind the myth that a lot of animal research involves pain and suffering for the animals.
Each week, we will ask you “true or false?” on commonly held beliefs - sometimes misconceptions - regarding animal research in the UK. Then, we share the results of the poll and provide the correct answer in a short reel.
We ask you "true or false?" on commonly held beliefs - sometimes misconceptions - regarding animal research in the UK. Then, then we share the results and provide pertinent information about the correct answer. This series is an attempt to increase transparency on the use of animals in research as well as correct any popular misinformation and myths.
Our first video asked: "True or false: Animals are used to test the safety of cosmetic products in the UK."
You answered: 86% said false.
Watch the video to find out the rest!
The majority of the human and animal medicines we have available today have been developed using dogs. Although dogs only account for 0.2% of all animal experiments in the UK, their use is essential to scientific, medical, and veterinary research.
For more information, please visit our website.
understandinganimalresearch.org.uk/beaglewiki
understandinganimalresearch.org.uk/what-is-animal-research/a-z-animals/dog
labanimaltour.org
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On 2-3 May 2024, we celebrated this important landmark with a conference dedicated to openness so that the worldwide openness community could come together, share ideas, and learn from each other. Here are some of our highlights!
concordatopenness.org.uk
For more information, please visit our website.
https://www.understandinganimalresear...
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Opossums are rarely used in scientific research but they still play an important role in developmental studies. This is because they are born at a similar stage to a 6-week-old human foetus.
For more information, please visit our website.
https://www.understandinganimalresear...
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Credits
Checking babies in mother opossum's pouch by Amphibiansunrise
Link: youtube.com/watch?v=nasBURpeiHw&t=9s
Creative Commons license http://creativecommons.org/licenses/by/4.0 for CC BY 4.0
Only 2% of total procedures in Great Britain are carried out on sheep but they play an important role in studying neurodegenerative diseases. This is because they have similar neuroanatomical structures as humans.
For more information, please visit our website.
https://www.understandinganimalresear...
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Credits
The University of Manchester case study: A day in the life of an animal technologist


