Finally Hopeful: The Root Causes of Depression | Dr. James Greenblatt @Codytalks11
Finally Hopeful: The Root Causes of Depression | Dr. James Greenblatt  @Codytalks11
Uploaded February 2026 | Updated September 2026, 1 hour ago
In this episode of the Coach Cody Podcast, we sit down (again!) with Dr. James Greenblatt, MD — a dual board-certified psychiatrist and internationally recognized pioneer in functional and integrative psychiatry, known for his work on low-dose nutritional lithium and root-cause mental health care.

We talk about why conventional psychiatry often becomes “symptom → prescription” medicine, and how functional psychiatry takes a test-then-treat approach by looking at things like nutrient deficiencies, hormones, gut health, genetics (including MTHFR), and metabolic factors that can drive depression and anxiety.

Topics we cover:

Functional vs integrative vs conventional psychiatry (and why “lifestyle changes” alone may not be enough)

Why labs are so often skipped in mental health care — and why that’s a problem

The big ones Dr. Greenblatt sees constantly: vitamin D and “normal but not optimal” B12

Celiac disease and malabsorption as a commonly missed root cause

Low-dose lithium orotate: what it is, how it differs from prescription lithium, and why he recommends simple standalone dosing

Antidepressants: why he’s not anti-medication, but believes patients deserve honest conversations about side effects and withdrawal

Ketamine: when it can help, when clinics get out of control, and why you should address root causes first

What gives him the most hope right now: the research is finally catching up

📘 Dr. Greenblatt’s new book: Finally Hopeful: The Personalized, Whole-Body Plan to Find and Fix the Root Causes of Your Depression

Website: jamesgreenblattmd.com
Connect with Psychiatry Redefined: psychiatryredefined.org

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Finally Hopeful: The Root Causes of Depression | Dr. James Greenblatt

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