Cancer Is Not One Disease Garvan Institute of Medical Research 2026-09-22 | Cancer Is Not One Disease
Welcome to Garvan Garvan Institute of Medical Research 2023-06-15 | We see a future where we’re able to stop disease before it starts.It's within reach.https://www.garvan.org.au/
Reshaping the future of pancreatic cancer public seminar Garvan Institute of Medical Research 2023-06-14 | It’s time to reshape the future for people living with pancreatic cancer. The five-year survival rate for pancreatic cancer in Australia is 12.2% and only three out of ten of people will survive one year after their diagnosis. One of the reasons pancreatic cancer, is referred to as a ‘silent disease’ is that it’s frequently diagnosed in the later stages of growth. This is because the pancreas is located behind the stomach and the cancer can remain undetected until it grows large enough to affect nearby organs. Prognosis is poor for patients with pancreatic cancer, and alarmingly, treatments and survival rates have not changed for almost 40 years. At Garvan, our aim is to triple survival rates by 2030.Speakers• Mara-Jean Tilley, Director, GRF• Dr Sean Porazinski• Dr Kendelle MurphySign up to our seminars here: https://www.garvan.org.au/tours-events/public-seminars/
Help Triple survival rates for pancreatic cancer Garvan Institute of Medical Research 2023-05-31 | ...
Women in Science seminar Garvan Institute of Medical Research 2023-03-08 | At Garvan we are committed to encouraging woman to flourish in their careers. Join us to celebrate some of the women who change our world every day – experts in data and genomics, cancer and immunology. Hear about their work, personal stories, heroes, experiences and challenges they have faced. Spaces are limited in the auditorium, so registration is essential.Speakers: Dr Amelia Parker, Associate Professor Sarah Kummerfeld, Associate Professor Elissa Deenick and Dr Venessa Chin
60 years of discovery Garvan Institute of Medical Research 2023-02-21 | Come on a revolutionary journey with us through Garvan’s 60-year history. You will hear from Garvan’s leading scientists and executive directors and see how their work has shaped Garvan and the world of medical science. Spaces are limited in the auditorium, so registration is essential.Speakers:Executive Director (interim) - Professor Peter Croucher, Professor John Shine, Dr Warren Kidson, Professor Chris Goodnow, Professor Susan ClarkExecutive Director (interim), Professor Peter CroucherProfessor Peter Croucher joined Garvan in 2011 and is the current Executive Director (interim). Peter is a bone biologist and cancer researcher, with a longstanding fascination for disorders of the skeleton, particularly osteoporosis and cancer-associated bone disease.Before becoming Executive Director, Peter was Deputy Director of Garvan, and led Garvan’s Healthy Ageing Research.Professor John ShineProfessor John Shine was Garvan’s Executive Director from 1990–2011. His name is known to most undergraduate biology students for his role in defining the Shine-Dalgarno gene sequence, which is responsible for the initiation and termination of protein-synthesis. John has several other significant scientific ‘firsts’ under his belt. He was the first to clone a human hormone gene; he was responsible for cloning of an endorphin gene; and he was the first to demonstrate that hormone genes cloned in bacteria could be expressed in a biologically active form. He also determined the first sequence responsible for replication of a cancer-causing virus.Dr Warren KidsonDr Warren Kidson has had a distinguished career as an endocrinologist and researcher in the area of type 1 diabetes. After graduating from UNSW Medicine, Dr Warren Kidson trained in paediatric diabetes at the Royal Alexandra Hospital for Children, while working in adult diabetes and endocrinology at the Garvan Institute of Medical Research. His premise was that the complications of type 1 diabetes seen in early adulthood begin to develop in childhood. He started the first camp for adolescents with diabetes in NSW and later edited Diabetes Conquest, the national magazine for people with diabetes.In 1998, Warren was one of the first clinicians in the world to treat women with polycystic ovarian syndrome with metformin. At the time this drug was used exclusively for type 2 diabetes.Professor Chris GoodnowProfessor Chris Goodnow is a world-renowned immunologist who joined Garvan in 2015 and took up the role of Executive Director in 2018. His research focus is to understand the cause of immune disorders and develop more effective, personalised treatments. Scientifically, Chris is best known for integrating molecular genetics and genomics with immunology. He leads Hope Research – a transformative research program that aims to uncover a common cause for all autoimmune disease. He holds The Bill and Patricia Ritchie Foundation Chair as Head of the Immunogenomics Lab, is an NHMRC Investigator, and is Professor and Director of the Cellular Genomics Futures Institute at UNSW Sydney.Professor Susan ClarkProfessor Susan Clark is a molecular biologist by training and is the Head of the Epigenetics Laboratory at Garvan. In 2004 Susan started at Garvan and led the Epigenetics Research Program in Cancer Research. Her DNA methylation studies over the last 25 years have initiated profound questions about the importance of epigenetics in early development and in disease, especially in cancer. Susan has made extensive ground-breaking discoveries relating to DNA methylation patterns in normal and cancer genomes, that have led to the commercialisation of new methylation-based tests for early cancer detection.The techniques she pioneered in the early 1990s have revolutionised and now underpin epigenomic research.
Revolutionising triple negative breast cancer treatment Garvan Institute of Medical Research 2022-10-31 | Triple negative breast cancer is an aggressive disease with a greater likelihood of spreading around the body and recurring within five years than other breast cancers. Join us to hear from Associate Professor Christine Chaffer. Her team has found that an experimental drug, seviteronel, combined with chemotherapy, could be twice as effective in reducing the size of tumours than chemotherapy alone. Spaces are limited in the Auditorium so registration is essential.You can register to attend one of our future public seminars here: https://www.garvan.org.au/tours-events/public-seminars/Support this research here: https://www.garvan.org.au/support-us/in-our-sights
Join us for breast cancer seminar with A/Prof Christine Chaffer Garvan Institute of Medical Research 2022-10-19 | Revolutionising triple negative breast cancer treatment.Thursday, 27th October 2022, 10:30am to 11:30am (AEDT)Triple negative breast cancer is an aggressive disease with a greater likelihood of spreading around the body and recurring within five years than other breast cancers. Join us to hear from Associate Professor Christine Chaffer. Her team has found that an experimental drug, seviteronel, combined with chemotherapy, could be twice as effective in reducing the size of tumours than chemotherapy alone. Spaces are limited in the Auditorium so registration is essential.
Higher body temperature alters key protein in auto inflammatory disorder Garvan Institute of Medical Research 2022-10-19 | Groundbreaking research offers insights into understanding the inflammatory disorder mevalonate kinase deficiency, and reveals new potential treatment approaches for this devastating disease.
2022 Future Leader Fellowship Garvan Institute of Medical Research 2022-10-18 | Congratulations A/Prof Jodie Ingles for being awarded the 2022 Future Leader Fellowship from the Heart Foundation to support her research into Genomics of inherited cardiovascular diseases.
From the Breast Cancer Lab to You Garvan Institute of Medical Research 2022-10-11 | ‘From the Breast Cancer Lab to You’ is our annual community update on breast cancer and includes presentation from Garvan and international research leaders, oncologists, patients and funding organisations.Presentations include updates on research advances in new treatments, drug resistance and metastasis, as well as new clinical trials.
Garvan recognised for commitment to mental health Garvan Institute of Medical Research 2022-10-10 | October 10 is World Mental Health Day - a day to raise awareness of mental health issues worldwide and to mobilise efforts to support mental health. Garvan prioritises mental health and well-being, offering various policies, activities and tools to help our people. Mental Health First Aid Australia has recently recognised us for our commitment to embedding Mental Health First Aid training and creating a mentally healthy workplace.
Triple-negative breast cancer: a potential new treatment is now in sight Garvan Institute of Medical Research 2022-09-30 | Breast cancer is the most commonly diagnosed cancer in Australia. Approximately 15,000 women are affected each year, many of whom are under 40. Triple-negative breast cancer (TNBC) is highly invasive, has no current targeted treatment and affects about 15% of those diagnosed with breast cancer.Garvan is leading a world-first clinical trial of a potential new treatment for TNBC. It could dramatically improve survival rates for patients and even block tumour growth. This clinical trial also has the potential to impact other cancer types such as ovarian, renal, liver and glioblastoma.This is why your support today is so vital.https://www.garvan.org.au/support-us/in-our-sights
Pancreatic cancer clinical trial to test new approach to treatment Garvan Institute of Medical Research 2022-08-22 | New cancer drug reportedly breaks down pancreatic tumours 9 News Australia
Genetic clues to age-related macular degeneration revealed Garvan Institute of Medical Research 2022-08-02 | The discovery of molecular signatures of age-related macular degeneration will help with better diagnosis and treatment of this progressive eye disease.Better diagnosis and treatment of the incurable eye disease age-related macular degeneration is a step closer, thanks to the discovery of new genetic signatures of the disease.Scientists from the Garvan Institute of Medical Research, the University of Melbourne, the Menzies Institute for Medical Research at the University of Tasmania and the Centre for Eye Research Australia, reprogrammed stem cells to create models of diseased eye cells, and then analysed DNA, RNA and proteins to pinpoint the genetic clues.Read the full story here: http://ow.ly/oCfQ50K6X1E
New Drug - Seviteronel can switch aggressive cancer cells Garvan Institute of Medical Research 2022-06-21 | This animation represents cancer cells dividing out of control and shows one cancer-associated molecule; androgen receptor that contributes to the aggressive state of some cancer cells. Associate Professor Christine Chaffer is leading research that investigates how a new drug called Seviteronel may switch cells out of this aggressive state and render them sensitive to chemotherapy again. Animation and VO by Dr Kate Patterson, Garvan Institute. Animation made with Autodesk Maya, Molecular Maya and compositing with Adobe After Effects. Narration:Our organs and tissues are made up of healthy cells that exist in an organised but delicate balance.Cancer occurs when some of these cells start to divide out of control, in many cases multiplying into a tumour and impacting on the surrounding healthy tissue.Chemotherapy, is often used to eradicate cancer but it is less effective on cancer cells that are naturally more aggressive.In some cancers, the chemotherapy itself can drive the emergence of resistant cancer cells.We discovered that inside these aggressive cells, androgen signalling is required for the cancer cells to transform into a resistant state.In normal cells, the androgen receptor is activated by hormones that bind to the receptor which then controls the appropriate growth and development of the cell.In aggressive cancer cells, the androgen receptor is extremely abundant and highly active, which contributes to the aggressive state of the cell.A new drug called seviteronel can switch cells out of this aggressive state by blocking the hormones that activate the androgen receptor. This makes cells sensitive to chemotherapy again. Using Sevi in a combination treatment approach may improve the effectiveness of chemotherapy and, ultimately, improve outcomes for patients.
Getting ahead of COVID-19 Garvan Institute of Medical Research 2022-06-02 | Our team here at Garvan are focussing our expertise, leading-edge technology and unique research capabilities towards developing a next generation, “universal” COVID vaccine. These are vaccines which generate antibodies to regions of the virus that cannot be easily mutated. The goal of using such vaccines across the population is to protect us not just against current variants of the virus, but also against future variants. Please join Dr Burnett in person in our Garvan Auditorium or online for our Public Seminar to hear more about her work on this project.To learn more about this research or to donate directly to this research project: https://www.garvan.org.au/support-us/getting-ahead-of-covid-19
The science of osteoporosis and how common treatments work Garvan Institute of Medical Research 2022-05-12 | This video explores deep inside the bone and illustrates how bone is truly a living organ inside the body, not just an inanimate skeleton. With over 50% of older adults having poor bone health, building a strong skeleton in early life is the best insurance to prevent future fractures. This can be achieved through weight bearing exercise and adequate calcium and vitamin D intake. This video has been developed by Kate Patterson of the Garvan Institute of Medical Research funded by the Australian Government Osteoporosis Consumer Awareness Grant for educational purposes.Music by Max Viktorov, Published by Pond5.
Harnessing genomics for families with inherited heart diseases Garvan Institute of Medical Research 2022-04-04 | A/Prof Jodie Ingles is harnessing genomics and big data to improve clarity and care for families with inherited heart diseases. Genomics is increasingly used to diagnose genetic disease and give families answers about their health. However, a clear diagnosis is often only the beginning. A/Prof Jodie Ingles’ and her team are harnessing the power of genomics to understand how people’s underlying genetic changes impact on inherited heart diseases while also finding ways to communicate and refine this information to improve care for families. Dr Ingles’ pioneering work bridges the gap between clinical research into heart diseases, genomics and data science, and health outcomes for patients. Join us for our upcoming seminar with A/Prof Ingles to hear about this critical clinical genomics research improving care for families with inherited heart diseases.Support life-changing medical research:https://www.garvan.org.au/support-us/the-power-of-genomicshttps://www.garvan.org.au
The Power of Genomics Garvan Institute of Medical Research 2022-02-15 | Thousands of Australians die every year from sudden cardiac death (SCD). At Garvan, we’re using genomics to better understand how to prevent diseases and their potentially traumatic outcomes, such as SCD.Every year, sudden cardiac death (SCD) occurs in 18,000 Australians, including children, teens and young adults who may have previously presented as healthy and well. A SCD occurs when the heart goes in to cardiac arrest.We know that when SCD occurs in young people, the cause is often an underlying inherited heart disease such as hypertrophic cardiomyopathy (HCM). But there is so much we don’t yet understand about the genetics of inherited heart diseases, which can have life-changing impacts on individuals and their families.Associate Professor Jodie Ingles, Head of the Clinical Genomics Lab at the Center for Population Genomics, has been a genetic counsellor for over 18 years. She’s witnessed firsthand the significant trauma and grief caused by sudden cardiac death in the young. A/Prof Ingles’ pioneering work in cardiac genomics aims to understand how we can use genomics to find a diagnosis for people and predict who will experience the most severe outcomes of these diseases – and to translate these findings into real-world clinical settings.Her research is an essential step forward in discovering how to better diagnose and treat these rare yet potentially devastating genetic diseases. Ultimately, A/Prof Ingles aims to prevent the tragedy of SCD for young people and their families.Support A.Prof Ingles research and Garvan here: https://www.garvan.org.au/support-us/give-now
A novel approach to treating obesity Garvan Institute of Medical Research 2021-12-07 | A/Prof Yan-Chuan (Yan) Shi is a clinical scientist and group leader of Garvan’s Neuroendocrinology group in the Healthy Ageing theme. She has a PhD in Medicine and a Master’s degree in Nutrition and medical qualifications that are recognised in both Australia and China, giving her and her group unique strengths in research, translation and collaboration. Her research primarily focuses on the regulation of food intake and energy metabolism.This video is an excerpt from our "Breakthrough Science 2021" seminar. You can view the entire seminar and Q&A here: https://www.youtube.com/watch?v=JqCsy... Learn more about our research here: https://www.garvan.org.au
Softening pancreatic cancer to improve chemotherapy response Garvan Institute of Medical Research 2021-12-07 | Dr David Herrmann is a Senior Research Officer focusing on cancer in Garvan’s Invasion and Metastasis laboratory. He completed his PhD in Germany, joining Garvan in 2013. His work focuses on observing and understanding the behaviour of tumours in the body to pinpoint critical events that drive the spread of cancer. This information is then used to optimise therapies that target cancer spread and have the potential to extend cancer survivorship.This video is an excerpt from our "Breakthrough Science 2021" seminar. You can view the entire seminar and Q&A here: https://www.youtube.com/watch?v=JqCsy... Learn more about our research here: https://garvan.org.au
Live tissue imaging reveals insight into bone and tumour cell communication Garvan Institute of Medical Research 2021-12-07 | A/Prof Michelle McDonald is Group Leader of Garvan’s Bone Microenvironment Group. Her research uses new imaging techniques that she has developed to research dormant and actively-growing tumour cells within living bone, and to visualise bone cells in real-time. She completed her PhD examining bone therapeutics to improve fracture repair at The Kids Research Institute. Since then Michelle’s work has led to a better understanding of responses to osteoporosis therapies and her group is now working on approaches to modify bone cell activity to prevent bone destruction caused by cancer and suppress metastatic tumour growth in bone.This video is an excerpt from our "Breakthrough Science 2021" seminar. You can view the entire seminar and Q&A here: https://www.youtube.com/watch?v=JqCsy... Learn more about our research here: https://www.garvan.org.au
Developing strategies for future-proofed COVID-19 vaccines resistant to variants Garvan Institute of Medical Research 2021-12-07 | Dr Deborah Burnett is a Research Officer with Garvan’s Immunogenomics laboratory and a Senior Lecturer at St Vincent’s Clinical School. She completed her PhD at Garvan and was awarded an NHMRC Fellowship to undertake research understanding the role of antibodies in normal vaccine responses and in autoimmune diseases.This video is an excerpt from our "Breakthrough Science 2021" seminar. You can view the entire seminar and Q&A here: youtube.com/watch?v=JqCsy5ehvYI Learn more about our research here: garvan.org.au
Breakthrough Science 2021 Garvan Institute of Medical Research 2021-12-01 | 2021 has been an exciting year of research at Garvan. Our scientists focus on a wide array of diseases and we’ve seen some remarkable research advances in cancer, metabolic disease and osteoporosis. This year, Garvan researchers have discovered a new type of bone cell and trialled new approaches to ‘prime’ tumours to make chemotherapy more effective. They have also revealed the action of a receptor that could lead to safer ways to prevent and treat obesity.Join us to hear from our world-class researchers to learn about our pioneering science of 2021 and how these new findings will affect people’s lives.Speakers: Dr Deborah Burnett, Dr David Herrmann, A/Prof Michelle McDonald and A/Prof Yan-Chuan (Yan) ShiDr Deborah Burnett is a Research Officer with Garvan’s Immunogenomics laboratory and a Senior Lecturer at St Vincent’s Clinical School. She completed her PhD at Garvan and was awarded an NHMRC Fellowship to undertake research understanding the role of antibodies in normal vaccine responses and in autoimmune diseases.Dr David Herrmann is a Senior Research Officer focusing on cancer in Garvan’s Invasion and Metastasis laboratory. He completed his PhD in Germany, joining Garvan in 2013. His work focuses on observing and understanding the behaviour of tumours in the body to pinpoint critical events that drive the spread of cancer. This information is then used to optimise therapies that target cancer spread and have the potential to extend cancer survivorship.A/Prof Michelle McDonald is Group Leader of Garvan’s Bone Microenvironment Group. Her research uses new imaging techniques that she has developed to research dormant and actively-growing tumour cells within living bone, and to visualise bone cells in real time. She completed her PhD examining bone therapeutics to improve fracture repair at The Kids Research Institute. Since then Michelle’s work has led to better understanding of responses to osteoporosis therapies and her group is now working on approaches to modify bone cell activity to prevent bone destruction caused by cancer and supress metastatic tumour growth in bone.A/Prof Yan-Chuan (Yan) Shi is a clinical scientist and group leader of Garvan’s Neuroendocrinology group in the Healthy Ageing theme. She has a PhD in Medicine and a Master’s degree in Nutrition and medical qualifications that are recognised in both Australia and China, giving her and her group unique strengths in research, translation and collaboration. Her research primarily focuses on the regulation of food intake and energy metabolism.
Accelerating genomic diagnosis of disease Garvan Institute of Medical Research 2021-10-28 | Genomic tests are increasingly used to diagnose genetic disease & give families answers about their health. In this seminar, Dr Ira Deveson & Dr Kishore Kumar will go through some exciting new approaches to accelerate diagnosis and profoundly impact people’s lives.
Breast Cancer 2021 Seminar Garvan Institute of Medical Research 2021-10-08 | Hosted by Prof Elgene Lim, A/Prof Alex Swarbrick and Dr Elizabeth Caldon, this year’s seminar will include Prof Geoffrey Lindeman, one of Australia’s eminent breast cancer researchers. The seminar will also include an update on Garvan’s breast cancer research and clinical trials at St Vincent’s hospital.
Celebrating Strong Women in Science Garvan Institute of Medical Research 2021-08-19 | In this seminar, we celebrate the scientific contributions of speakers Sarah Alexandrou, Prof Susan Clark, A/Prof Elissa Deenick and recognise how their work can inspire students to create a better world through science. Disclaimer: Our seminars are not intended to be a substitute for professional medical advice and should not be relied on as health or personal advice.To support this research, please visit: www.garvan.org.au/give-now Follow us:Garvan website: www.garvan.org.auFacebook: www.facebook.com/garvaninstituteInstagram: www.instagram.com/garvaninstituteTwitter: twitter.com/GarvanInstituteLinkedIn: www.linkedin.com/company/garvan-institute-of-medical-research
Auto Antibodies Garvan Institute of Medical Research 2021-08-04 | "Auto Antibodies" is an animation created by Dr Ofir Shein-Lumbroso about the work by Dr Joanne Reed at the Garvan Institute of Medical Research. Our immune system helps to protect us against unwanted pathogens like viruses and bacteria that can make us unwell. In patients with an auto-immune disorder, antibodies are produced that target the patient's own cells and tissues. In this animation, you will see large antibody complexes called IgM that clump together and create aggregates in small blood vessels, leading to inflammation and vasculitis.
What Does Osteoporosis Look Like - a 360 degree animation Garvan Institute of Medical Research 2021-07-14 | Tilt your device or use VR goggles to explore deep inside a living bone. The osteoblasts build bone. The osteoclasts collapse bone. These two cells work in sync to replace old bone cells. When the activity of the osteoclasts is greater than osteoblasts, the bone weakens as more bone is taken away than replaced. This leads to complications over time such as osteoporosis which affects over 50% of older adults. Building and maintaining strong skeleton in early life is the best insurance to prevent future fractures. This can be achieved through weight bearing exercise and adequate calcium and vitamin D intake.This video has been developed by Kate Patterson of the Garvan Institute of Medical Research funded by the Australian Government Osteoporosis Consumer Awareness Grant for educational purposes.Thank you to Mark Arrebola of Friend Factory https://friendfactory.com.au for modelling and texturing of internal bone structure. Music by Max Viktorov (BMI), IPI#376566026 Published by Pond5.
What Is Osteoporosis - Science Animation Garvan Institute of Medical Research 2021-07-14 | This video explores deep inside the bone and illustrates how bone is truly a living organ inside the body, not just an inanimate skeleton. With over 50% of older adults having poor bone health, building a strong skeleton in early life is the best insurance to prevent future fractures. This can be achieved through weight bearing exercise and adequate calcium and vitamin D intake. This video has been developed by Kate Patterson of the Garvan Institute of Medical Research funded by the Australian Government Osteoporosis Consumer Awareness Grant for educational purposes.Thank you to Mark Arrebola of Friend Factory https://friendfactory.com.au for modelling and texturing of internal bone structure. Music by Max Viktorov, Published by Pond5.
Meet Dr Amali Mallawaarachchi Garvan Institute of Medical Research 2021-07-06 | Dr Mallawaarachchi is a Clinician-Scientist whose current research focuses on understanding the molecular basis of polycystic kidney disease through the application of the latest sequencing technologies. Learn more about Dr Amali's research: https://www.garvan.org.au/people/amamalTo support this research: www.garvan.org.au/give-nowFollow usGarvan website: www.garvan.org.auFacebook: www.facebook.com/garvaninstituteInstagram: www.instagram.com/garvaninstituteTwitter: twitter.com/GarvanInstituteLinkedIn: www.linkedin.com/company/garvan-institute-of-medical-research
Prof Paul Timpson, Dr Kendelle Murphy, Bronwyn Terrill – The Power of Personalised Medicine Garvan Institute of Medical Research 2021-06-29 | Speakers04:22 Bronwyn Terrill16:18 Dr Kendelle Murphy28:12 Prof Paul Timpson36:20 discussionPersonalised medicine is the future of health and medicine. It uses uniquely personal information, like your DNA or genetic information, to help guide health-related decisions. Garvan researchers are already using genomic technology to conduct medical research, identifying genes and changes to genes that cause or influence some of the major diseases affecting society today. Join us to hear about some of the exciting research underway.Disclaimer: Our seminars are not intended to be a substitute for professional medical advice and should not be relied on as health or personal adviceTo support this research: www.garvan.org.au/give-nowFollow usGarvan website: www.garvan.org.auFacebook: www.facebook.com/garvaninstituteInstagram: www.instagram.com/garvaninstituteTwitter: twitter.com/GarvanInstituteLinkedIn: www.linkedin.com/company/garvan-institute-of-medical-research
Welcome to Garvan Garvan Institute of Medical Research 2021-06-17 | Fighting disease is in our DNA. We've gathered some of the best scientific minds together under one roof.We're a genomics powerhouse. We see a future where your DNA is used to prevent and treat disease.Our researchers ask the tough questions and work collaboratively to create a healthier future for everyone.Garvan.org.au
Garvan Bequests Garvan Institute of Medical Research 2021-05-31 | A bequest to Garvan is a meaningful way to make a lasting impact on the health and lives of future generations. By supporting Garvan in your Will, you will be helping your loved ones as well as your friends and neighbours loved ones – now and in the future.
Bronwyn Terrill, A/Prof Sarah Kummerfeld, A/Prof Cindy Ma - Get into your genes Garvan Institute of Medical Research 2021-05-27 | Speakers 02:36 Bronwyn Terrill – Investigating our DNA, genes and genomes13:17 A/Prof Sarah Kummerfeld – Genomics in whole of life healthcare 26:31 A/Prof Cindy Ma – CIRCA discovering the unknownAlmost every disease has a genetic component. At Garvan, our fundamental goal is to understand genome biology and its impact on disease. Our vision is to use all the information encoded in our genome to better predict, diagnose, treat and ultimately prevent disease. In this seminar, you will learn the basics of genetics and hear from our researchers about their pioneering research projects.Disclaimer: Our seminars are not intended to be a substitute for professional medical advice and should not be relied on as health or personal advice. To support this research: https://www.garvan.org.au/give-nowFollow usGarvan website: https://www.garvan.org.auFacebook: facebook.com/garvaninstituteInstagram: instagram.com/garvaninstituteTwitter: twitter.com/GarvanInstituteLinkedIn: linkedin.com/company/garvan-institute-of-medical-research
Accelerated pancreatic cancer trials Garvan Institute of Medical Research 2021-05-13 | Garvan researchers are about to embark on a bold new clinical trial for pancreatic cancer, just three years after early stage pre-clinical trials.
Professor Jacqueline Center - The Story of Our Bones Garvan Institute of Medical Research 2021-04-15 | Our bones are in a continuous state of remodelling through life, where old and damaged bones are replaced by new bones. As we age, this rebuilding process can become unbalanced, leaving bones thinner and more fragile. Hear from one of Garvan’s top osteoporosis experts, Professor Jacqueline Center and gain an appreciation for what our bones do for us.Disclaimer: Our seminars are not intended to be a substitute for professional medical advice and should not be relied on as health or personal adviceTo support this research: www.garvan.org.au/give-nowFollow usGarvan website: www.garvan.org.auFacebook: www.facebook.com/garvaninstituteInstagram: www.instagram.com/garvaninstituteTwitter: twitter.com/GarvanInstituteLinkedIn: www.linkedin.com/company/garvan-institute-of-medical-research
A/Prof Marina Pajic- Harnessing the immune system against pancreatic cancer Garvan Institute of Medical Research 2021-03-19 | In this seminar, you'll hear how renowned pancreatic cancer researcher, Associate Professor Marina Pajic, is using a new world first intravital imaging technology, to directly see into the ‘dark spaces’ of cancer tumours, to improve outcomes and make cancer immunotherapy more effective for pancreatic patients.Disclaimer: Our seminars are not intended to be a substitute for professional medical advice and should not be relied on as health or personal adviceTo support this research: www.garvan.org.au/give-nowFollow usGarvan website: www.garvan.org.auFacebook: www.facebook.com/garvaninstituteInstagram: www.instagram.com/garvaninstituteTwitter: twitter.com/GarvanInstituteLinkedIn: www.linkedin.com/company/garvan-institute-of-medical-research
Garvan Heroes – Andrea’s story Garvan Institute of Medical Research 2021-03-09 | 1 in 3 women and 1 in 4 men over 50 have osteoporosis.Osteoporosis reduces the density and quality of bone, greatly increasing the risk of fracture. Approximately 50% of people with one osteoporotic fracture will have another – and of those with an osteoporotic hip fracture, 25% will die within six months. Garvan’s scientists have identified the genes that lead to the development of osteoporosis, with research now directed to discovering how to repair bone and to prevent osteoporosis in those with an increased risk of the disease.http://garvan.org.au
Garvan Heroes – Angela’s story Garvan Institute of Medical Research 2021-03-09 | 1 in 3 women and 1 in 4 men over 50 have osteoporosis.Osteoporosis reduces the density and quality of bone, greatly increasing the risk of fracture. Approximately 50% of people with one osteoporotic fracture will have another – and of those with an osteoporotic hip fracture, 25% will die within six months. Garvan’s scientists have identified the genes that lead to the development of osteoporosis, with research now directed to discovering how to repair bone and to prevent osteoporosis in those with an increased risk of the disease.http://garvan.org.au
Garvan Heroes – Ashleigh’s story Garvan Institute of Medical Research 2021-03-09 | 9 out of 10 people with Sjögren’s are women.Often characterised by dry mouth and dry eyes, Sjögren’s syndrome is an autoimmune disease where the glands that normally produce tears, saliva and sweat are attacked by immune cells. It can also affect other mucous membranes like the intestines and lungs. Garvan’s scientists use advanced techniques like single cell sequencing and flow cytometry to identify the molecular defects that cause this disease.http://garvan.org.au
Garvan Heroes – Brian’s story Garvan Institute of Medical Research 2021-03-09 | 100,000 Australians currently live with Parkinson’s disease. Parkinson’s disease is a gradually progressive disorder of the brain that affects movement, causing tremors and stiffness. Research into Parkinson’s disease at Garvan is multifaceted, focusing on early onset and its causes, new neuroprotection therapies to prevent progression, brain regeneration and repair, and of course, prevention. http://garvan.org.au
Garvan Heroes – George’s story Garvan Institute of Medical Research 2021-03-09 | Over 25,000 Australians live with Multiple Sclerosis.Multiple Sclerosis is a disease in which the immune system eats away at the protective covering of nerves. The resulting nerve damage disrupts communication between the brain and the body. The duration and severity of the symptoms, including vision loss, pain, fatigue and impaired coordination, can vary from person to person. Multiple Sclerosis is one of 44 autoimmune conditions being studied by the Hope Research team at Garvan, the Weizmann Institute of Science in Israel and Westmead Hospital.http://garvan.org.au
Garvan Heroes – Hosam’s story Garvan Institute of Medical Research 2021-03-09 | Uncommon cancers together represent around 37% of all cancers diagnosed.Rare cancers – like brain cancer – are the most common cause of disease-related death in Australia, including children. However, these cancers are often categorised as ‘neglected cancers’ due to research underfunding. Whole-genome sequencing led to the discovery that all cancers are linked to harmful genetic variants, so that instead of treating disease symptoms, we can now target the genetic variants causing them.http://garvan.org.au
Garvan Heroes – Kathren’s story Garvan Institute of Medical Research 2021-03-09 | The 5-year survival rate of pancreatic cancer is around 9%.When cells in the pancreas develop mutations in their DNA, they can grow into tumours. Garvan works to define the genetic characteristics of pancreatic cancer, developing biomarkers prognosis and therapeutic responsiveness, and understanding the molecular mechanisms of resistance in order to develop new treatment strategies.http://garvan.org.au
Garvan Heroes – Kieran’s story Garvan Institute of Medical Research 2021-03-09 | 1 in 8 Australians live with an autoimmune disease.Guillain-Barré syndrome is a rare autoimmune disease in which your body's immune system attacks your nerves, with weakness and tingling in your extremities usually being the first symptoms. These sensations can quickly spread, eventually paralysing your whole body. Guillain-Barré syndrome is one of 44 autoimmune conditions being studied by the Hope Research team at Garvan, the Weizmann Institute of Science in Israel and Westmead Hospital.http://garvan.org.au
Garvan Heroes – Nicole’s story Garvan Institute of Medical Research 2021-03-09 | 1 in 7 Australian women will be diagnosed with breast cancer by age 85.Breast cancer is not a single disease. Researchers now think there may be up to 10 subtypes, with differences in how aggressive the cancer is, and how it responds to treatment. Garvan’s research includes defining the genetic characteristics of breast cancer; developing biomarkers of prognosis and responsiveness to treatment; and understanding how cancers become resistant to treatment and identifying ways to overcome this. * Nicole is a BRCA1 carrierhttp://garvan.org.au
Garvan Heroes – Rosie’s story Garvan Institute of Medical Research 2021-03-09 | About 50% of people with PKD will have kidney failure by age 60.Polycystic kidney disease (PKD) is a genetic disorder that causes many fluid-filled cysts to grow in the kidneys. If too many cysts grow or if they get too big, the kidneys can become damaged, reducing kidney function and leading to failure. Garvan’s researchers are developing a better diagnostic method for PKD and have already shown that whole genome sequencing has the potential to transform the diagnosis of common inherited kidney disease, making the diagnostic process cheaper and more accurate.http://garvan.org.au
