Medicinal Genomics
Exploring the fascinating development of cannabinoid-producing trichomes - Zamir Punja, PhD
updated
TJ Martin is the VP of R&D at Abstrax Tech, Inc, a company that specializes in the research, development, and production of botanically derived and cannabis-inspired terpenes.
TJ and his team recently published a paper that identified several non-terpenoid compounds that are responsible for the unique aromas associated with exotic cannabis varieties, including the berry, tropical, candy, and fruity notes found in Zkittlez and Gelato as well as the rich, intense, chemical scents found in GMO. This research opens up a new world of aromatic compounds and challenges the idea of classifying cultivars based on terpenes alone.
Listen Now:
Our conversation covers:
⦿ How cannabis aroma affects consumer and patient experience
⦿ The variety of aromas the cannabis plant can produce and how it compares to other plants
⦿ Define exotic cannabis varieties and compare them to more prototypical cultivars
⦿ Why terpenes alone do not tell the entire aroma story in exotic cannabis varieties
⦿ How to communicate information about non-terpeninoid compounds to consumers and patients in a meaningful way
Thanks to this Episode’s Sponsor: Agilent Technologies
TJ and his team recently published a paper that identified several non-terpenoid compounds that are responsible for the unique aromas associated with exotic cannabis varieties, including the berry, tropical, candy, and fruity notes found in Zkittlez and Gelato as well as the rich, intense, chemical scents found in GMO. This research opens up a new world of aromatic compounds and challenges the idea of classifying cultivars based on terpenes alone.
We discuss:
- How cannabis aroma affects consumer and patient experience
- The variety of aromas the cannabis plant can produce and how it compares to other plants
- Define exotic cannabis varieties and compare them to more prototypical cultivars
- Why terpenes alone do not tell the entire aroma story in exotic cannabis varieties
- How to communicate information about non-terpeninoid compounds to consumers and patients in a meaningful way
Thanks to This Episode’s Sponsor: Agilent Technologies
Whether you manufacture or test cannabis, you face the challenge of delivering high-quality products, increasing sample volume, and meeting emerging regulations. Agilent offers best-in-class cannabis and hemp analysis solutions featuring robust instruments, software, services, and consumables. Their team of experts can develop, implement, and optimize methods to get you up and running quickly.
Learn more at agilent.com
Additional Resources
- Minor, Nonterpenoid Volatile Compounds Drive the Aroma Differences of Exotic Cannabis - pubs.acs.org/doi/10.1021/acsomega.3c04496
- Abstraxtech.com
[Podcast] Discovering New Aromatic Compounds in Cannabis with TJ Martin - youtu.be/nkPbZvZPFqk
- Cannasulfur Compounds: A New Class of Secondary Metabolites Discovered in Cannabis - youtu.be/K8QAwTSMSMY
- Cannabis Aroma Predicts User Experience with Adie Rae, PhD - youtu.be/-NBz7UggcFQ
- The Nose Knows: Aroma, but Not THC Mediates the Subjective Effects of Smoked and Vaporized Cannabis Flower - mdpi.com/2813-1851/1/2/8
- Register for CannMed 24 - cvent.me/1mGLAq
- What Makes CannMed Unique and Why You Don’t Want to Miss It - medicinalgenomics.com/what-makes-cannmed-unique
- Review the Podcast! - podcasts.apple.com/us/podcast/cannmed-coffee-talk/id1504218804
- CannMed Archive - cannmedevents.com/cannmed-video-archives
Dustin is also a true CannMed veteran, having participated in every CannMed event dating back to our first conference at Harvard Medical School. He returns to CannMed 24 this year as one of the medical practicum instructors and an oral presenter, presenting “The Art and Science of Combining Cannabinoids for Treatment Success”
We discuss:
* What attendees can expect from CannMed Medical Practicum
* The expansion of avialble cannabinoids and how Dustin evaluates new options
* Which Cannabinoid Dustin would choose if he could only use one to treat patients
* The difference between acidic and neutral forms of cannabinoids
* The process for combining cannabinoids
* Challenging old assumptions about the benefits of combining CBD and THC
Thanks to This Episode's Sponsor: Healer
Healer is a trusted, physician-developed medical cannabis brand founded to address the challenges of helping patients and health providers get the best results with safe, reliably dosable products and education on how to best use them. Healer’s distinctive product formulations and educational material are based on the work of leading cannabis clinician, Dr. Dustin Sulak, D.O.
Learn More at healer.com
Additional Resources
Healer.com
Register for CannMed 24 - cvent.me/1mGLAq
What Makes CannMed Unique and Why You Don’t Want to Miss It - medicinalgenomics.com/what-makes-cannmed-unique
Review the Podcast! - podcasts.apple.com/us/podcast/cannmed-coffee-talk/id1504218804
CannMed Archive - cannmedevents.com/cannmed-video-archives
Dustin is also a true CannMed veteran, having participated in every CannMed event dating back to our first conference at Harvard Medical School. He returns to CannMed 24 this year as one of the medical practicum instructors and an oral presenter, presenting “The Art and Science of Combining Cannabinoids for Treatment Success”
We discuss:
* What attendees can expect from CannMed Medical Practicum
* The expansion of avialble cannabinoids and how Dustin evaluates new options
* Which Cannabinoid Dustin would choose if he could only use one to treat patients
* The difference between acidic and neutral forms of cannabinoids
* The process for combining cannabinoids
* Challenging old assumptions about the benefits of combining CBD and THC
Thanks to This Episode's Sponsor: Healer
Healer is a trusted, physician-developed medical cannabis brand founded to address the challenges of helping patients and health providers get the best results with safe, reliably dosable products and education on how to best use them. Healer’s distinctive product formulations and educational material are based on the work of leading cannabis clinician, Dr. Dustin Sulak, D.O.
Learn More at healer.com
Additional Resources
Healer.com
Register for CannMed 24 - cvent.me/1mGLAq
What Makes CannMed Unique and Why You Don’t Want to Miss It - medicinalgenomics.com/what-makes-cannmed-unique
Review the Podcast! - podcasts.apple.com/us/podcast/cannmed-coffee-talk/id1504218804
CannMed Archive - cannmedevents.com/cannmed-video-archives
Dustin is also a true CannMed veteran, having participated in every CannMed event dating back to our first conference at Harvard Medical School. He returns to CannMed 24 this year as one of the medical practicum instructors and an oral presenter, presenting “The Art and Science of Combining Cannabinoids for Treatment Success”
We discuss:
* What attendees can expect from CannMed Medical Practicum
* The expansion of available cannabinoids and how Dustin evaluates new options
* Which Cannabinoid Dustin would choose if he could only use one to treat patients
* The difference between acidic and neutral forms of cannabinoids
* The process for combining cannabinoids
* Challenging old assumptions about the benefits of combining CBD and THC
Thanks to This Episode's Sponsor: Healer
Healer is a trusted, physician-developed medical cannabis brand founded to address the challenges of helping patients and health providers get the best results with safe, reliably dosable products and education on how to best use them. Healer’s distinctive product formulations and educational material are based on the work of leading cannabis clinician, Dr. Dustin Sulak, D.O.
Learn More at healer.com
Dustin is also a true CannMed veteran, having participated in every CannMed event dating back to our first conference at Harvard Medical School. He returns to CannMed 24 this year as one of the medical practicum instructors and an oral presenter, presenting “The Art and Science of Combining Cannabinoids for Treatment Success”
We discuss:
* What attendees can expect from CannMed Medical Practicum
* The expansion of avialble cannabinoids and how Dustin evaluates new options
* Which Cannabinoid Dustin would choose if he could only use one to treat patients
* The difference between acidic and neutral forms of cannabinoids
* The process for combining cannabinoids
* Challenging old assumptions about the benefits of combining CBD and THC
Thanks to This Episode's Sponsor: Healer
Healer is a trusted, physician-developed medical cannabis brand founded to address the challenges of helping patients and health providers get the best results with safe, reliably dosable products and education on how to best use them. Healer’s distinctive product formulations and educational material are based on the work of leading cannabis clinician, Dr. Dustin Sulak, D.O.
Learn More at healer.com
Additional Resources
Healer.com
Register for CannMed 24 - cvent.me/1mGLAq
What Makes CannMed Unique and Why You Don’t Want to Miss It - medicinalgenomics.com/what-makes-cannmed-unique
Review the Podcast! - podcasts.apple.com/us/podcast/cannmed-coffee-talk/id1504218804
CannMed Archive - cannmedevents.com/cannmed-video-archives
At CannMed 24, Ethan will present “Cannabinoid Hyperemesis Syndrome (CHS): Unraveling the Gordian Knot”. CHS is an enigmatic condition where some chronic, heavy users of THC develop a cyclic pattern of vomiting and nausea that is only relieved by hot bathing and topical capsaicin. Ethan and his coinvestigators surveyed more than 500 cannabis users, including 205 diagnosed CHS patients, and investigated genetic mutations in 28 CHS patients and 12 controls to identify behaviors and genetic markers that could indicate CHS risk.
During our conversation, we discuss:
⦿ What is CHS and who does it affect
⦿ Why cases of CHS appear to be on the rise
⦿ Possible genetic markers that could indicate CHS susceptibility
⦿ Steps cannabis users can take to prevent developing CHS
⦿ Why some people in the cannabis community don’t believe CHS is a real thing
⦿ And more!
Thanks to This Episode’s Sponsor: Cannabis Nurses Network
Established in 2015, the Cannabis Nurses Network™ is a professional nursing and professional development organization for nurses around the globe. By educating nurses on the science behind the plant and providing a global nursing network, nurses are supported and empowered to implement their knowledge within their community.
Learn more at cannabisnursesnetwork.com
Additional Resources
what-is-chs.com
ethanrusso.org
CReDO-science.com
Cannabinoid Hyperemesis Syndrome Survey and Genomic Investigation - pubmed.ncbi.nlm.nih.gov/34227878
Unraveling the Mystery of Cannabinoid Hyperemesis Syndrome – youtu.be/X-8im4X9HXM?si=lVWLPge3oRHD6o0vCannMed 2019 Panel
Register for CannMed 24 - cvent.me/1mGLAq
What Makes CannMed Unique and Why You Don’t Want to Miss It - medicinalgenomics.com/what-makes-cannmed-unique
Review the Podcast! - podcasts.apple.com/us/podcast/cannmed-coffee-talk/id1504218804
CannMed Archive - cannmedevents.com/cannmed-video-archives
At CannMed 24, Ethan will present “Cannabinoid Hyperemesis Syndrome (CHS): Unraveling the Gordian Knot”. CHS is an enigmatic condition where some chronic, heavy users of THC develop a cyclic pattern of vomiting and nausea that is only relieved by hot bathing and topical capsaicin. Ethan and his coinvestigators surveyed more than 500 cannabis users, including 205 diagnosed CHS patients, and investigated genetic mutations in 28 CHS patients and 12 controls to identify behaviors and genetic markers that could indicate CHS risk.
During our conversation, we discuss:
⦿ What is CHS and who does it affect
⦿ Why cases of CHS appear to be on the rise
⦿ Possible genetic markers that could indicate CHS susceptibility
⦿ Steps cannabis users can take to prevent developing CHS
⦿ Why some people in the cannabis community don’t believe CHS is a real thing
⦿ And more!
Thanks to This Episode’s Sponsor: Cannabis Nurses Network
Established in 2015, the Cannabis Nurses Network™ is a professional nursing and professional development organization for nurses around the globe. By educating nurses on the science behind the plant and providing a global nursing network, nurses are supported and empowered to implement their knowledge within their community.
Learn more at cannabisnursesnetwork.com
Additional Resources
what-is-chs.com
ethanrusso.org
CReDO-science.com
Cannabinoid Hyperemesis Syndrome Survey and Genomic Investigation - pubmed.ncbi.nlm.nih.gov/34227878
Unraveling the Mystery of Cannabinoid Hyperemesis Syndrome – youtu.be/X-8im4X9HXM?si=lVWLPge3oRHD6o0vCannMed 2019 Panel
Register for CannMed 24 - cvent.me/1mGLAq
What Makes CannMed Unique and Why You Don’t Want to Miss It - medicinalgenomics.com/what-makes-cannmed-unique
Review the Podcast! - podcasts.apple.com/us/podcast/cannmed-coffee-talk/id1504218804
CannMed Archive - cannmedevents.com/cannmed-video-archives
Listen Now: youtu.be/4h-NYwdfGTE
Dr. Ethan Russo is a board-certified neurologist, psychopharmacologist, and Founder/CEO of CReDO Science LLC. He is an internationally recognized authority on cannabis medicine. He has authored/edited seven books and has published more than 60 peer-reviewed articles. He also holds director/advisor positions with several cannabis therapeutics companies, and he was instrumental in developing Sativex® for pain and MS, and Epidiolex® for intractable epilepsy while at GW Pharmaceuticals.
At CannMed 24, Ethan will present “Cannabinoid Hyperemesis Syndrome (CHS): Unraveling the Gordian Knot”. View Here: cannmedevents.com/ethan-russo-md
Our conversation covers:
⦿ What is CHS and who does it affect
⦿ Why cases of CHS appear to be on the rise
⦿ Possible genetic markers that could indicate CHS susceptibility
⦿ Steps cannabis users can take to prevent developing CHS
⦿ Why some people in the cannabis community don’t believe CHS is a real thing
⦿ And more!
Thanks to this Episode’s Sponsor: @cannanursesnetwork
At CannMed 24, Ethan will present “Cannabinoid Hyperemesis Syndrome (CHS): Unraveling the Gordian Knot”. CHS is an enigmatic condition where some chronic, heavy users of THC develop a cyclic pattern of vomiting and nausea that is only relieved by hot bathing and topical capsaicin. Ethan and his coinvestigators surveyed more than 500 cannabis users, including 205 diagnosed CHS patients, and investigated genetic mutations in 28 CHS patients and 12 controls to identify behaviors and genetic markers that could indicate CHS risk.
During our conversation, we discuss:
What is CHS and who does it affect
Why cases of CHS appear to be on the rise
Possible genetic markers that could indicate CHS susceptibility
Steps cannabis users can take to prevent developing CHS
Why some people in the cannabis community don’t believe CHS is a real thing
and more
Thanks to This Episode’s Sponsor: Cannabis Nurses Network
Established in 2015, the Cannabis Nurses Network™ is a professional nursing and professional development organization for nurses around the globe. By educating nurses on the science behind the plant and providing a global nursing network, nurses are supported and empowered to implement their knowledge within their community.
Learn more at cannabisnursesnetwork.com
Additional Resources
what-is-chs.com
ethanrusso.org
CReDO-science.com
Cannabinoid Hyperemesis Syndrome Survey and Genomic Investigation - pubmed.ncbi.nlm.nih.gov/34227878
Unraveling the Mystery of Cannabinoid Hyperemesis Syndrome – youtu.be/X-8im4X9HXM?si=lVWLPge3oRHD6o0vCannMed 2019 Panel
Register for CannMed 24 - cvent.me/1mGLAq
What Makes CannMed Unique and Why You Don’t Want to Miss It - medicinalgenomics.com/what-makes-cannmed-unique
Review the Podcast! - podcasts.apple.com/us/podcast/cannmed-coffee-talk/id1504218804
CannMed Archive - cannmedevents.com/cannmed-video-archives
At CannMed 24 Akeem will present Effect of Cannflavins on Mitigating a Motor Neuron Disease.
During our conversation we discuss:
⦿ The minor molecules found in cannabis that Canurta is investigating for therapeutics
⦿ Canurta’s process for evaluating indications for cannflavins and polyphenols
⦿ How the diverse molecules in cannabis make it a great therapeutic for multifactoral diseases like ALS
⦿ The potential for cannflavins and polyphenols may be used as a anti-inflammatory nutraceutical
⦿ and more!
Thanks to This Episode's Sponsor: American Cannabis Nurses Association
ACNA is a national nursing organization whose mission is to advance excellence in cannabis nursing practice through advocacy, collaboration, education, research, and policy development. Founded in 2010, ACNA continues to work on providing its members with up-to-date cannabis information and resources to care for patients who use cannabis.
Join them today at cannabisnurses.org and be a part of the change.
Additional Resources
Akeem on LinkedIn - linkedin.com/in/akeemgardner
Email Akeem at Akeem@Canurta.com
Canurta Journal Page - canurta.com/journal
Register for CannMed 24 - cvent.me/1mGLAq
What Makes CannMed Unique and Why You Don’t Want to Miss It - medicinalgenomics.com/what-makes-cannmed-unique
Review the Podcast! - podcasts.apple.com/us/podcast/cannmed-coffee-talk/id1504218804
CannMed Archive - cannmedevents.com/cannmed-video-archives
At CannMed 24 Akeem will present Effect of Cannflavins on Mitigating a Motor Neuron Disease.
During our conversation we discuss:
⦿ The minor molecules found in cannabis that Canurta is investigating for therapeutics
⦿ Canurta’s process for evaluating indications for cannflavins and polyphenols
⦿ How the diverse molecules in cannabis make it a great therapeutic for multifactoral diseases like ALS
⦿ The potential for cannflavins and polyphenols may be used as a anti-inflammatory nutraceutical
⦿ and more!
Thanks to This Episode's Sponsor: American Cannabis Nurses Association
ACNA is a national nursing organization whose mission is to advance excellence in cannabis nursing practice through advocacy, collaboration, education, research, and policy development. Founded in 2010, ACNA continues to work on providing its members with up-to-date cannabis information and resources to care for patients who use cannabis.
Join them today at cannabisnurses.org and be a part of the change.
Additional Resources
Akeem on LinkedIn - linkedin.com/in/akeemgardner
Email Akeem at Akeem@Canurta.com
Canurta Journal Page - canurta.com/journal
Register for CannMed 24 - cvent.me/1mGLAq
What Makes CannMed Unique and Why You Don’t Want to Miss It - medicinalgenomics.com/what-makes-cannmed-unique
Review the Podcast! - podcasts.apple.com/us/podcast/cannmed-coffee-talk/id1504218804
CannMed Archive - cannmedevents.com/cannmed-video-archives
Akeem Gardner is the Founder and CEO of Canurta. He is an innovative entrepreneur with over five years of experience in industrial hemp enterprises. He has a proven track record in leading high-performance teams that work across multi-channel platforms and strategically aligning profitability with sustainability and economic development in Ontario.
At CannMed 24 Akeem will present "Effect of Cannflavins on Mitigating a Motor Neuron Disease." View Here: cannmedevents.com/akeem-gardner
Our conversation covers:
⦿ The minor molecules found in cannabis that Canurta is investigating for therapeutics
⦿ Canurta’s process for evaluating indications for cannflavins and polyphenols
⦿ How the diverse molecules in cannabis make it a great therapeutic for multifactoral diseases like ALS
⦿ The potential for cannflavins and polyphenols may be used as a anti-inflammatory nutraceutical
⦿ and more!
Thanks to this Episode’s Sponsor: American Cannabis Nurses Association (ACNA)
At CannMed 24 Akeem will present Effect of Cannflavins on Mitigating a Motor Neuron Disease.
During our conversation we discuss:
* The minor molecules found in cannabis that Canurta is investigating for therapeutics
* Canurta’s process for evaluating indications for cannflavins and polyphenols
* How the diverse molecules in cannabis make it a great therapeutic for multifactoral diseases like ALS
* The potential for cannflavins and polyphenols may be used as a anti-inflammatory nutraceutical
* and more
Thanks to This Episode's Sponsor: American Cannabis Nurses Association
ACNA is a national nursing organization whose mission is to advance excellence in cannabis nursing practice through advocacy, collaboration, education, research, and policy development. Founded in 2010, ACNA continues to work on providing its members with up-to-date cannabis information and resources to care for patients who use cannabis.
Join them today at cannabisnurses.org and be a part of the change.
Additional Resources
Akeem on LinkedIn - linkedin.com/in/akeemgardner
Email Akeem at Akeem@Canurta.com
Canurta Journal Page - canurta.com/journal
Register for CannMed 24 - cvent.me/1mGLAq
What Makes CannMed Unique and Why You Don’t Want to Miss It - medicinalgenomics.com/what-makes-cannmed-unique
Review the Podcast! - podcasts.apple.com/us/podcast/cannmed-coffee-talk/id1504218804
CannMed Archive - cannmedevents.com/cannmed-video-archives
At CannMed 24 he will present “Understanding the Prevalence and Risks Associated with Endotoxins on Cannabis Flower”, which will include novel research he did to measure the level of endotoxins in store-bought cannabis flower. Our conversation covers:
* What inspired Kevin to look into endotoxin levels on cannabis
* Which microbes produce endotoxins
* How endotoxins affect humans
* Whether remediation techniques mask endotoxin risks
* and more
Thanks to This Episode's Sponsor: Agilent Technologies
At CannMed 24 he will present “Understanding the Prevalence and Risks Associated with Endotoxins on Cannabis Flower”, which will include novel research he did to measure the level of endotoxins in store-bought cannabis flower. Our conversation covers:
* What inspired Kevin to look into endotoxin levels on cannabis
* Which microbes produce endotoxins
* How endotoxins affect humans
* Whether remediation techniques mask endotoxin risks
* and more
Thanks to This Episode's Sponsor: Agilent Technologies.
Whether you manufacture or test cannabis, you face the challenge of delivering high-quality products, increasing sample volume, and meeting emerging regulations. Agilent offers best-in-class cannabis and hemp analysis solutions featuring robust instruments, software, services, and consumables. Their team of experts can develop, implement, and optimize methods to get you up and running quickly.
Learn more at agilent.com
Additional Resources
High levels of endotoxins in commercial cannabis flower [Pre-Print] - osf.io/preprints/osf/gdqbx
Total Yeast and Mold - A Comparison Study - Jini Glaros [CannMed 23 Presentation] - youtu.be/Q8Aa1x0L0yM
Register for CannMed 24 - cvent.me/1mGLAq
Review the Podcast! - podcasts.apple.com/us/podcast/cannmed-coffee-talk/id1504218804
CannMed Archive - cannmedevents.com/cannmed-video-archives
After advising on various transactions in the life science sector, David took an interest in the cannabis sector and started advising cannabis companies before eventually re-founding Golden Eagle Partners in 2014 to focus on advising companies across the cannabis sector. Before Golden Eagle Partners, David served at leading investment banking firms including Pacific Growth Equities, Caris & Company, and Headwaters MB. During his banking tenures he has advised private and public biotechnology and medical device companies in various transactions including IPOs, public offerings, private offerings, mergers and acquisitions totaling over $500 million in value.
David and Golden Eagle Partners will host a Capital Markets Workshop at CannMed 24 which will explore a global perspective of the hurdles, issues, and concepts around funding cannabinoid and cannabis innovation.
During our conversation we discuss:
⦿ What attendees can expect from the Capital Markets Workshop
⦿ Redefining the cannabis nomenclature
⦿ The likelihood the DEA will reschedule cannabis this year
⦿ Pharma’s growing interest in cannabis-derived compounds
⦿ Challenges cannabis innovators face when raising capital
Thanks to This Episode’s Sponsor: Golden Eagle Partners
Learn more at: goldeneaglepartners.com
After advising on various transactions in the life science sector, David took an interest in the cannabis sector and started advising cannabis companies before eventually re-founding Golden Eagle Partners in 2014 to focus on advising companies across the cannabis sector. Before Golden Eagle Partners, David served at leading investment banking firms including Pacific Growth Equities, Caris & Company, and Headwaters MB. During his banking tenures he has advised private and public biotechnology and medical device companies in various transactions including IPOs, public offerings, private offerings, mergers and acquisitions totaling over $500 million in value.
David and Golden Eagle Partners will host a Capital Markets Workshop at CannMed 24 which will explore a global perspective of the hurdles, issues, and concepts around funding cannabinoid and cannabis innovation.
During our conversation we discuss:
⦿ What attendees can expect from the Capital Markets Workshop
⦿ Redefining the cannabis nomenclature
⦿ The likelihood the DEA will reschedule cannabis this year
⦿ Pharma’s growing interest in cannabis-derived compounds
⦿ Challenges cannabis innovators face when raising capital
Thanks to This Episode’s Sponsor: Golden Eagle Partners
Learn more at: goldeneaglepartners.com
Learn More about the Capital Markets Workshop: cannmedevents.com/capital-markets-workshop
After advising on various transactions in the life science sector, David took an interest in the cannabis sector and started advising cannabis companies before eventually re-founding Golden Eagle Partners in 2014 to focus on advising companies across the cannabis sector. Before Golden Eagle Partners, David served at leading investment banking firms including Pacific Growth Equities, Caris & Company, and Headwaters MB. During his banking tenures he has advised private and public biotechnology and medical device companies in various transactions including IPOs, public offerings, private offerings, mergers and acquisitions totaling over $500 million in value.
David and Golden Eagle Partners will host a Capital Markets Workshop at CannMed 24 which will explore a global perspective of the hurdles, issues, and concepts around funding cannabinoid and cannabis innovation.
During our conversation we discuss:
⦿ What attendees can expect from the Capital Markets Workshop
⦿ Redefining the cannabis nomenclature
⦿ The likelihood the DEA will reschedule cannabis this year
⦿ Pharma’s growing interest in cannabis-derived compounds
⦿ Challenges cannabis innovators face when raising capital
Thanks to This Episode’s Sponsor: Golden Eagle Partners
Learn more at: goldeneaglepartners.com
After advising on various transactions in the life science sector, David took an interest in the cannabis sector and started advising cannabis companies before eventually re-founding Golden Eagle Partners in 2014 to focus on advising companies across the cannabis sector. Before Golden Eagle Partners, David served at leading investment banking firms including Pacific Growth Equities, Caris & Company, and Headwaters MB. During his banking tenures he has advised private and public biotechnology and medical device companies in various transactions including IPOs, public offerings, private offerings, mergers and acquisitions totaling over $500 million in value.
David and Golden Eagle Partners will host a Capital Markets Workshop at CannMed 24 which will explore a global perspective of the hurdles, issues, and concepts around funding cannabinoid and cannabis innovation.
During our conversation we discuss:
What attendees can expect from the Capital Markets Workshop
Redefining the cannabis nomenclature
The likelihood the DEA will reschuelde cannabis this year
Pharma’s growing interest in cannabis-derived compounds
Challenges cannabis innovators face when raising capital
Thanks to This Episode’s Sponsor: Golden Eagle Partners
Golden Eagle Partners are transactional experts, specializing in mergers, acquisitions, reverse mergers, financings and incremental transactions such as licensing, joint ventures and co-development arrangements. Their combined experience in the early stages of the cannabis and life science sectors allows them to confidently close strategic and financing transactions that match the near- and long-term goals of their clients.
Learn more at goldeneaglepartners.com
Additional Resources
Reclassifying Cannabis: What The HHS Recommendation Means For The Cannabis Market [Benzinga Podcast] - youtube.com/live/yMLGNp3qLyA?si=IlEMGCG6QeRnNDv8
David Traylor on LinkedIn - linkedin.com/in/david-w-traylor
Register for CannMed 24 - cvent.me/1mGLAq
Review the Podcast! - podcasts.apple.com/us/podcast/cannmed-coffee-talk/id1504218804
CannMed Archive - cannmedevents.com/cannmed-video-archives
Bonni Goldstein is one of the country’s most respected and experienced medical cannabis physicians, having treated thousands of patients with medical cannabis. She is the owner and medical director of Canna-Centers Wellness & Education. She is Clinical Advisor to Cannformatics, and she is the author of the book titled “Cannabis is Medicine: How Medical Cannabis and CBD Are Healing Everything from Anxiety to Chronic Pain”.
Bonni has participated in every CannMed event since we started in 2016, she is a perennial Advisory Board Member, and she will lead the CannMed Medical practicum again in 2024. During our conversation we talked about:
What attendees can expect from CannMed Medical Practicum
New research that she is excited about concerning THCA and CBDA
Her method for customizing cannabinoid formulations for her patients
The many barriers preventing patients from using cannabis
How the cannabinoid medicine options have expanded over the last decade
The difficulty of keeping up with the cannabis medicine literature
Thanks to This Episode’s Sponsor: The DENT Institute
With more than 300,000 patient visits per year, the DENT Neurologic Institute ranks among the largest neuroscience centers in North America. Its 24 subspecialty clinics often treat the most challenging neurologic conditions including but not limited to Migraine, Chronic pain, ALS, MS, Parkinson’s, Dementia, Neuro-Oncology, etc. With our mission of advancing neuroscience, we established a cannabis clinic in 2016 to aid in the treatment of these chronic conditions seen throughout our institute.
Learn more at dentinstitute.com
Additional Resources
Cannabis is Medicine by Bonni Goldstein, MD [Book] - amazon.com/Cannabis-Medicine-Medical-Healing-Everything/dp/031650078X
@bonnigoldsteinmd on Instagram - instagram.com/bonnigoldsteinmd
Bonni Goldstein, MD on LinkedIn - linkedin.com/in/bonnigoldsteinmd
Review the Podcast! - podcasts.apple.com/us/podcast/cannmed-coffee-talk/id1504218804
CannMed Archive - cannmedevents.com/cannmed-video-archives
During our conversation, we discussed:
The different allowable limits for THC levels in drivers
The relationship between THC levels and impaired driving
The best fluid to test for THC impairment
The additive effects of combining alcohol and cannabis on driving impairment
The differences in how alcohol and cannabis affect driving performance
Thanks to this episode’s sponsor: Trusted Canna Nurse
Trusted Canna Nurse was founded by Megan Mbengue and Ariane Williams, two nurses who are dedicated to bridging the gap between traditional medicine and the world of cannabis and psychedelics. They specialize in creating evidence-based treatment plans for all ages that address chronic illnesses, treatment-resistant conditions, mental health, autism, and more.
Learn more at trustedcannanurse.com
Additional Resources
- The Utility of THC Cutoff Levels in Blood and Saliva for Detection of Impaired Driving - liebertpub.com/doi/full/10.1089/can.2022.0187
- Canadian Cannabis Survey - canada.ca/en/health-canada/services/drugs-medication/cannabis/research-data.html
- The “Next Day” Effects of Cannabis Use: A Systematic Review - liebertpub.com/doi/10.1089/can.2022.0185
- Register for CannMed 24 - web.cvent.com/event/ab5a72c8-0b7f-48d0-90e4-e7b4aa71f639/regPage:7b1d74cb-5a31-4ee4-8d74-0f42f411f3fa?rp=45d139f5-cb9c-4122-84a9-65456109bf02
- Review the Podcast! - podcasts.apple.com/tt/podcast/cannmed-coffee-talk/id1504218804
- CannMed Archive - cannmedevents.com/cannmed-video-archives
During our conversation, we discussed:
The different allowable limits for THC levels in drivers
The relationship between THC levels and impaired driving
The best fluid to test for THC impairment
The additive effects of combining alcohol and cannabis on driving impairment
The differences in how alcohol and cannabis affect driving performance
Thanks to this episode’s sponsor: Trusted Canna Nurse
Trusted Canna Nurse was founded by Megan Mbengue and Ariane Williams, two nurses who are dedicated to bridging the gap between traditional medicine and the world of cannabis and psychedelics. They specialize in creating evidence-based treatment plans for all ages that address chronic illnesses, treatment-resistant conditions, mental health, autism, and more.
Learn more at trustedcannanurse.com
Additional Resources
- The Utility of THC Cutoff Levels in Blood and Saliva for Detection of Impaired Driving - liebertpub.com/doi/full/10.1089/can.2022.0187
- Canadian Cannabis Survey - canada.ca/en/health-canada/services/drugs-medication/cannabis/research-data.html
- The “Next Day” Effects of Cannabis Use: A Systematic Review - liebertpub.com/doi/10.1089/can.2022.0185
- Register for CannMed 24 - web.cvent.com/event/ab5a72c8-0b7f-48d0-90e4-e7b4aa71f639/regPage:7b1d74cb-5a31-4ee4-8d74-0f42f411f3fa?rp=45d139f5-cb9c-4122-84a9-65456109bf02
- Review the Podcast! - podcasts.apple.com/tt/podcast/cannmed-coffee-talk/id1504218804
- CannMed Archive - cannmedevents.com/cannmed-video-archives
During our conversation, we discussed:
The different allowable limits for THC levels in drivers
The relationship between THC levels and impaired driving
The best fluid to test for THC impairment
The additive effects of combining alcohol and cannabis on driving impairment
The differences in how alcohol and cannabis affect driving performance
Thanks to this episode’s sponsor: Trusted Canna Nurse
Trusted Canna Nurse was founded by Megan Mbengue and Ariane Williams, two nurses who are dedicated to bridging the gap between traditional medicine and the world of cannabis and psychedelics. They specialize in creating evidence-based treatment plans for all ages that address chronic illnesses, treatment-resistant conditions, mental health, autism, and more.
Learn more at trustedcannanurse.com
#shorts
Additional Resources
- The Utility of THC Cutoff Levels in Blood and Saliva for Detection of Impaired Driving - liebertpub.com/doi/full/10.1089/can.2022.0187
- Canadian Cannabis Survey - canada.ca/en/health-canada/services/drugs-medication/cannabis/research-data.html
- The “Next Day” Effects of Cannabis Use: A Systematic Review - liebertpub.com/doi/10.1089/can.2022.0185
- Register for CannMed 24 - web.cvent.com/event/ab5a72c8-0b7f-48d0-90e4-e7b4aa71f639/regPage:7b1d74cb-5a31-4ee4-8d74-0f42f411f3fa?rp=45d139f5-cb9c-4122-84a9-65456109bf02
- Review the Podcast! - podcasts.apple.com/tt/podcast/cannmed-coffee-talk/id1504218804
- CannMed Archive - cannmedevents.com/cannmed-video-archives
During our conversation, we discussed:
The different allowable limits for THC levels in drivers
The relationship between THC levels and impaired driving
The best fluid to test for THC impairment
The additive effects of combining alcohol and cannabis on driving impairment
The differences in how alcohol and cannabis affect driving performance
Thanks to this episode’s sponsor: Trusted Canna Nurse
Trusted Canna Nurse was founded by Megan Mbengue and Ariane Williams, two nurses who are dedicated to bridging the gap between traditional medicine and the world of cannabis and psychedelics. They specialize in creating evidence-based treatment plans for all ages that address chronic illnesses, treatment-resistant conditions, mental health, autism, and more.
Learn more at trustedcannanurse.com
Additional Resources
- The Utility of THC Cutoff Levels in Blood and Saliva for Detection of Impaired Driving - liebertpub.com/doi/full/10.1089/can.2022.0187
- Canadian Cannabis Survey - canada.ca/en/health-canada/services/drugs-medication/cannabis/research-data.html
- The “Next Day” Effects of Cannabis Use: A Systematic Review - liebertpub.com/doi/10.1089/can.2022.0185
- Register for CannMed 24 - web.cvent.com/event/ab5a72c8-0b7f-48d0-90e4-e7b4aa71f639/regPage:7b1d74cb-5a31-4ee4-8d74-0f42f411f3fa?rp=45d139f5-cb9c-4122-84a9-65456109bf02
- Review the Podcast! - podcasts.apple.com/tt/podcast/cannmed-coffee-talk/id1504218804
- CannMed Archive - cannmedevents.com/cannmed-video-archives
Dr. Karla Gage is Assistant Professor of Weed Science and Plant Biology at Southern Illinois University Carbondale, where she received her Ph.D. in Plant Biology with a focus in Weed Ecology in 2013. In short, Karla is a weed expert, but not in the weed you smoke, but rather the weeds you pull. Her research focuses on using Integrated Weed Management to control and suppress weeds in midwestern US rotational crops, including corn, soybean, wheat, sorghum, and now hemp.
During our conversation we discussed:
⦾ What negative effects weeds can have on hemp
⦾ Which weed species are threatening to hemp
⦾ Herbicides that are approved for hemp and the threat of herbicide resistance
⦾ Integrated weed management strategies, such as, crop rotation, cover crops, and chaff lining, plastic coverings, and more
⦾ How ferral hemp varieties may have traits to help breed more resistant hemp varieties.
Thanks to this Episode’s Sponsor: Rare Earth Genomics
Rare Earth Genomics Texas is a partnership formed to accelerate hemp research and produce critical tools for the farmer. REG’s mission is to increase likelihood of a successful harvest through genetic analysis and rigorous environmental testing of vigorous cultivars. Reliable datasets, analytic tools and stable germplasm are core to the program. Success of the farmer is the goal!
Dr. Karla Gage is Assistant Professor of Weed Science and Plant Biology at Southern Illinois University Carbondale, where she received her Ph.D. in Plant Biology with a focus in Weed Ecology in 2013. In short, Karla is a weed expert, but not in the weed you smoke, but rather the weeds you pull. Her research focuses on using Integrated Weed Management to control and suppress weeds in midwestern US rotational crops, including corn, soybean, wheat, sorghum, and now hemp.
During our conversation we discussed:
⦾ What negative effects weeds can have on hemp
⦾ Which weed species are threatening to hemp
⦾ Herbicides that are approved for hemp and the threat of herbicide resistance
⦾ Integrated weed management strategies, such as, crop rotation, cover crops, and chaff lining, plastic coverings, and more
⦾ How ferral hemp varieties may have traits to help breed more resistant hemp varieties.
Thanks to this Episode’s Sponsor: Rare Earth Genomics
Rare Earth Genomics Texas is a partnership formed to accelerate hemp research and produce critical tools for the farmer. REG’s mission is to increase likelihood of a successful harvest through genetic analysis and rigorous environmental testing of vigorous cultivars. Reliable datasets, analytic tools and stable germplasm are core to the program. Success of the farmer is the goal!
With hands-on expertise, he retailed and distributed hydroponics supplies, sourced grow lights globally, created Biojuice nutrients, designed Phresh filter air quality systems, and simplified micropropagation cloning – creating the leading microclone tissue culture kits in 2005.
During our conversation, we discussed:
- The basics of tissue culture
- Tissue culture as propagation alternative to cloning
- How mother plants can lead to pathogen infections and loss of vigor
- Combining tissue culture and qPCR to eliminate pathogens, such as hop latent viroid
- and more!
Additional Resources
- microclone.com
- Microclone on YouTube -
youtube.com/playlist?list=PL3889D2A0445E5B4A
- Register for CannMed 24 -
cvent.me/1mGLAq
- Submit an Abstract for CannMed 24 -
cvent.com/c/abstracts/ec356f22-1e98-4c0f-a46c-0fb1d4d9ade8
- Review the Podcast! -
podcasts.apple.com/tt/podcast/cannmed-coffee-talk/id1504218804
- CannMed Archive - cannmedevents.com/cannmed-video-archives
- CannMed Community Board [Facebook Group] - facebook.com/groups/cannmedcommunity
Danielle and her colleagues recently published a systematic review of 20 studies that examine the next-day effects of THC. As the study states, “The length of time an individual should wait following cannabis use before performing safety-sensitive tasks, is a critical issue.” Some government agencies and experts recommend individuals avoid performing safety-sensitive tasks for at least 24 hours. It should not surprise you to learn that the data suggests a much shorter impairment window.
During our conversation, we discuss:
- The different types of studies the authors reviewed and the criteria they used to evaluate them
- The different tests administered to measure impairment
- How next-day effects of THC compare to acute effects
- How next-day effects are different in medicinal cannabis patients vs recreational users
- What methods are available to determine THC impairment in drivers
- What is a reasonable impairment window for THC
Additional Resources
- The “Next Day” Effects of Cannabis Use: A Systematic Review - liebertpub.com/doi/10.1089/can.2022.0185
- Determining the magnitude and duration of acute Δ9-tetrahydrocannabinol (Δ9-THC)-induced driving and cognitive impairment: A systematic and meta-analytic review - sciencedirect.com/science/article/pii/S0149763421000178?via%3Dihub#!
- Lambert Initiative for Cannabinoid Therapeutics - https://www.sydney.edu.au/lambert/
- Review the Podcast! - podcasts.apple.com/tt/podcast/cannmed-coffee-talk/id1504218804
- CannMed Archive - cannmedevents.com/cannmed-video-archives
- CannMed Community Board [Facebook Group] - facebook.com/groups/cannmedcommunity
He has published some of the first major retrospective research trials on Medical Marijuana in Headaches and other neurologic disorders and lectures both nationally and internationally and is recognized as a leader in the fields of Neuroimaging, Headache Medicine, Neuro-Oncology, and Medical Cannabis. Dr. Mechtler is also a member for he CannMed 24 Advisory Board.
During our conversation we discuss:
- How the DENT Institute is uniquely positioned to study medical cannabis for a variety of conditions
- Results from recent studies conducted at the DENT Cannabis Clinic
- The challenges of studying cannabis medicine and how a proposed rescheduling could help
- The ongoing struggle to convince fellow clinicians and medical associations that medical cannabis is legitimate
Thanks to This Episode's Sponsor: The DENT Institute
With more than 300,000 patient visits per year, the DENT Neurologic Institute ranks among the largest neuroscience centers in North America. Its 24 subspecialty clinics often treat the most challenging neurologic conditions including but not limited to Migraine, Chronic pain, ALS, MS, Parkinson’s, Dementia, and Neuro-Oncology. With their mission of advancing neuroscience, the Dent Institute established a cannabis clinic in 2016 to aid in the treatment of these chronic conditions seen throughout the institute.
He has published some of the first major retrospective research trials on Medical Marijuana in Headaches and other neurologic disorders and lectures both nationally and internationally and is recognized as a leader in the fields of Neuroimaging, Headache Medicine, Neuro-Oncology, and Medical Cannabis. Dr. Mechtler is also a member for he CannMed 24 Advisory Board.
During our conversation we discuss:
- How the DENT Institute is uniquely positioned to study medical cannabis for a variety of conditions
- Results from recent studies conducted at the DENT Cannabis Clinic
- The challenges of studying cannabis medicine and how a proposed rescheduling could help
- The ongoing struggle to convince fellow clinicians and medical associations that medical cannabis is legitimate
Thanks to This Episode's Sponsor: The DENT Institute
With more than 300,000 patient visits per year, the DENT Neurologic Institute ranks among the largest neuroscience centers in North America. Its 24 subspecialty clinics often treat the most challenging neurologic conditions including but not limited to Migraine, Chronic pain, ALS, MS, Parkinson’s, Dementia, and Neuro-Oncology. With their mission of advancing neuroscience, the Dent Institute established a cannabis clinic in 2016 to aid in the treatment of these chronic conditions seen throughout the institute.
Dr. Karla Gage is Assistant Professor of Weed Science and Plant Biology at Southern Illinois University Carbondale, where she received her Ph.D. in Plant Biology with a focus in Weed Ecology in 2013. In short, Karla is a weed expert, but not in the weed you smoke, but rather the weeds you pull. Her research focuses on using Integrated Weed Management to control and suppress weeds in midwestern US rotational crops, including corn, soybean, wheat, sorghum, and now hemp.
During our conversation we discussed:
⦾ What negative effects weeds can have on hemp
⦾ Which weed species are threatening to hemp
⦾ Herbicides that are approved for hemp and the threat of herbicide resistance
⦾ Integrated weed management strategies, such as, crop rotation, cover crops, and chaff lining, plastic coverings, and more
⦾ How ferral hemp varieties may have traits to help breed more resistant hemp varieties
#shorts
Thanks to this Episode’s Sponsor: Rare Earth Genomics
Dr. Karla Gage is Assistant Professor of Weed Science and Plant Biology at Southern Illinois University Carbondale, where she received her Ph.D. in Plant Biology with a focus in Weed Ecology in 2013. In short, Karla is a weed expert, but not in the weed you smoke, but rather the weeds you pull. Her research focuses on using Integrated Weed Management to control and suppress weeds in midwestern US rotational crops, including corn, soybean, wheat, sorghum, and now hemp.
During our conversation we discussed:
⦾ What negative effects weeds can have on hemp
⦾ Which weed species are threatening to hemp
⦾ Herbicides that are approved for hemp and the threat of herbicide resistance
⦾ Integrated weed management strategies, such as, crop rotation, cover crops, and chaff lining, plastic coverings, and more
⦾ How ferral hemp varieties may have traits to help breed more resistant hemp varieties.
Thanks to this Episode’s Sponsor: Rare Earth Genomics
Rare Earth Genomics Texas is a partnership formed to accelerate hemp research and produce critical tools for the farmer. REG’s mission is to increase likelihood of a successful harvest through genetic analysis and rigorous environmental testing of vigorous cultivars. Reliable datasets, analytic tools and stable germplasm are core to the program. Success of the farmer is the goal!
With hands-on expertise, he retailed and distributed hydroponics supplies, sourced grow lights globally, created Biojuice nutrients, designed Phresh filter air quality systems, and simplified micropropagation cloning – creating the leading microclone tissue culture kits in 2005.
During our conversation, we discussed:
- The basics of tissue culture
- Tissue culture as propagation alternative to cloning
- How mother plants can lead to pathogen infections and loss of vigor
- Combining tissue culture and qPCR to eliminate pathogens, such as hop latent viroid
- and more!
Additional Resources
- microclone.com
- Microclone on YouTube -
youtube.com/playlist?list=PL3889D2A0445E5B4A
- Register for CannMed 24 -
cvent.me/1mGLAq
- Submit an Abstract for CannMed 24 -
cvent.com/c/abstracts/ec356f22-1e98-4c0f-a46c-0fb1d4d9ade8
- Review the Podcast! -
podcasts.apple.com/tt/podcast/cannmed-coffee-talk/id1504218804
- CannMed Archive - cannmedevents.com/cannmed-video-archives
- CannMed Community Board [Facebook Group] - facebook.com/groups/cannmedcommunity
He has published some of the first major retrospective research trials on Medical Marijuana in Headaches and other neurologic disorders and lectures both nationally and internationally and is recognized as a leader in the fields of Neuroimaging, Headache Medicine, Neuro-Oncology, and Medical Cannabis. Dr. Mechtler is also a member for he CannMed 24 Advisory Board.
During our conversation we discuss:
- How the DENT Institute is uniquely positioned to study medical cannabis for a variety of conditions
- Results from recent studies conducted at the DENT Cannabis Clinic
- The challenges of studying cannabis medicine and how a proposed rescheduling could help
- The ongoing struggle to convince fellow clinicians and medical associations that medical cannabis is legitimate
Thanks to This Episode's Sponsor: The DENT Institute
With more than 300,000 patient visits per year, the DENT Neurologic Institute ranks among the largest neuroscience centers in North America. Its 24 subspecialty clinics often treat the most challenging neurologic conditions including but not limited to Migraine, Chronic pain, ALS, MS, Parkinson’s, Dementia, and Neuro-Oncology. With their mission of advancing neuroscience, the Dent Institute established a cannabis clinic in 2016 to aid in the treatment of these chronic conditions seen throughout the institute.
Bill Graham is the Founder of Microclone Tissue Culture, a company that provides tissue culture kits, consulting, and training to cannabis cultivators. With hands-on expertise, he retailed and distributed hydroponics supplies, sourced grow lights globally, created Biojuice nutrients, designed Phresh filter air quality systems, and simplified micropropagation cloning – creating the leading Microclone tissue culture kits in 2005.
Watch Now: youtube.com/watch?v=z18fxL7US-w
During our conversation, we discussed:
⦿ The basics of tissue culture
⦿ Tissue culture as propagation alternative to cloning
⦿ How mother plants can lead to pathogen infections and loss of vigor
⦿ Combining tissue culture and qPCR to eliminate pathogens, such as hop latent viroid
⦿ And more!
Thanks to this Episode’s Sponsor: Cambium Analytica
With hands-on expertise, he retailed and distributed hydroponics supplies, sourced grow lights globally, created Biojuice nutrients, designed Phresh filter air quality systems, and simplified micropropagation cloning - creating the leading Microclone tissue culture kits in 2005.
During our conversation we discussed:
* The basics of tissue culture
* Tissue culture as propagation alternative to cloning
* How mother plants can lead to pathogen infections and loss of vigor
* Combining tissue culture and qPCR to eliminate pathogens, such as hop latent viroid
* and more!
Thanks to This Episode's Sponsor: Cambium Analytica
Cambium Analytica, provides analytical, product development, and quality assurance services for the natural foods, botanical products, natural pharmaceutical, and dietary supplement industries. Cambium is a leading research organization that is focused on leveraging its expertise on drug discovery and method development, to be a research partner of choice for new innovative companies in the burgeoning botanical medicines space. Their focus on applying analytical techniques in combination with sensory, product development, and consumer research is driving advancement in natural product quality and innovation.
Learn more at cambiumanalytica.com
Additional Resources
- microclone.com
- Microclone on YouTube - youtube.com/playlist?list=PL3889D2A0445E5B4A
- Register for CannMed 24 - web.cvent.com/event/ab5a72c8-0b7f-48d0-90e4-e7b4aa71f639/regPage:7b1d74cb-5a31-4ee4-8d74-0f42f411f3fa?rp=45d139f5-cb9c-4122-84a9-65456109bf02
- Submit an Abstract for CannMed 24 - cvent.com/c/abstracts/ec356f22-1e98-4c0f-a46c-0fb1d4d9ade8
- Review the Podcast! - podcasts.apple.com/tt/podcast/cannmed-coffee-talk/id1504218804
- CannMed Archive - cannmedevents.com/cannmed-video-archives
- CannMed Community Board [Facebook Group] - facebook.com/groups/cannmedcommunity
David W. Denning is a Professor of Infectious Diseases in Global Health at The University of Manchester in the United Kingdom. He was the founding president, executive director, and CEO of Global Action For Fungal Infections, an organization dedicated to reducing the worldwide burden of fungal disease.
In 2016, he became the director of the National Aspergillosis Centre in Manchester, which treats patients with chronic pulmonary aspergillosis (CPA), and led the committee that developed the first CPA guidelines. He chairs the editorial board of a website which focuses on aspergillus and he leads an organization which provides education on fungal diseases.
During our conversation, we discuss:
◎ Should cannabis be tested for pathogenic Aspergillus
◎ Should there be an allowable limit for pathogenic Aspergillus?
◎ Is Aspergillosis only a concern for immunocompromised patients?
◎ Are the number of Aspergillosis cases under reported?
◎ How difficult is Aspergillosis to diagnose and treat?
◎ How ubiquitous is Aspergillus in the air we breathe?
◎ And so much more!
In 2016, he became the director of the National Aspergillosis Centre in Manchester, which treats patients with chronic pulmonary aspergillosis (CPA), and led the committee that developed the first CPA guidelines. He chairs the editorial board of a website that focusses on Aspergillus and he leads an organization that provides education on fungal diseases.
In short, Dr. Denning is the leading authority on all things Aspergillus, and we asked him many of the questions that have been debated on social media recently, including:
* Should cannabis be tested for pathogenic Aspergillus
* Should there be an allowable limit for pathogenic Aspergillus?
* Is Apergillosis only a concern for immunocompromised patients?
* Are the number of Aspergillosis cases under reported?
* How difficult is Aspergillosis to diagnose and treat?
* How ubiquitous is Aspergillus in the air we breathe?
* and so much more.
Allow us to introduce you to the CannMed 24 Innovation and Investment Summit, an exclusive experience of discovery, development, and networking with innovators from around the world. Since 2016, CannMed has regularly featured some of the greatest minds in medicinal plant medicine, cultivation, and safety testing. It is the most sought-after forum in which to announce the latest research and technologies while networking with current and prospective customers.
In this supercharged environment, CannMed 24 gathers stakeholders from across the industry, along with leaders from financial institutions who come together to forge enduring partnerships.
Learn more at cannmedevents.com
I spoke with Mitch about the various environmental factors that contribute to cannabis yield, specifically light, temperature, humidity, and CO2. Mitch does a great job explaining the energy cascade, which describes the underlying mechanisms that plants use to convert photons to energy and ultimately biomass. Mitch also explains how those factors can be manipulated to not only increase yield but also make better use of resources.
I spoke with Mitch about the various environmental factors that contribute to cannabis yield, specifically light, temperature, humidity, and CO2. Mitch does a great job explaining the energy cascade, which describes the underlying mechanisms that plants use to convert photons to energy and ultimately biomass. Mitch also explains how those factors can be manipulated to not only increase yield but also make better use of resources.
I really enjoyed the conversation, and I expect we will see Mitchell on the CannMed stage very soon.
Thanks to This Episode's Sponsor: Advanced Nutrients.
Founded in 1999, Advanced Nutrients was the first to develop a complete nutrient system that unlocks the true genetic potential of the cannabis plant. Since its inception, the brand has introduced more than 50 innovations to the cultivation community, and continues to revolutionize the space through proprietary scientific discoveries.
Learn more at advancednutrients.com
Additional Resources
- Elevated UV photon fluxes minimally affected cannabinoid concentration in a high-CBD cultivar - frontiersin.org/articles/10.3389/fpls.2023.1220585/full
- Cannabis lighting: Decreasing blue photon fraction increases yield but efficacy is more important for cost effective production of cannabinoids - journals.plos.org/plosone/article?id=10.1371/journal.pone.0248988
- Sustainable Cannabis Nutrition: Elevated root-zone phosphorus significantly increases leachate P and does not improve yield or quality - frontiersin.org/articles/10.3389/fpls.2022.1015652/full
- An approach to crop modeling with the energy cascade - researchgate.net/publication/11807032_An_approach_to_crop_modeling_with_the_energy_cascade?enrichId=rgreq-934adf2d7faf4322de75c8f47fe3da66-XXX&enrichSource=Y292ZXJQYWdlOzExODA3MDMyO0FTOjIyMjE5NDExMTEyNzU1MkAxNDI5OTg2NjEyMjc4&el=1_x_3&_esc=publicationCoverPdf
- Exploring the Limits of Crop Productivity - ncbi.nlm.nih.gov/pmc/articles/PMC1055676/pdf/plntphys00633-0369.pdf
- The Science and Technology of Medical Cannabis Cultivation Utah State University Couse - https://caas.usu.edu/labs/cpl/cannabis/online-course
- Review the Podcast! - podcasts.apple.com/tt/podcast/cannmed-coffee-talk/id1504218804
- CannMed Archive - cannmedevents.com/cannmed-video-archives
- CannMed Community Board [Facebook Group] - facebook.com/groups/cannmedcommunity
During our conversation, we discuss:
◎ What makes CBG one of Bonni’s favorite new cannabinoids
◎ What makes CBG a “bridge” cannabinoid between THC and CBD
◎ The difference between CBGA and CBG
◎ How CBG enhances the body’s natural endocannabinoid system
◎ How CBG works in combination with other cannabinoids
◎ Conditions for which CBG is a good fit
◎ Potential adverse reactions to CBG
◎ A preview of the CannMed Medical Practicum
Danielle and her colleagues recently published a systematic review of 20 studies that examine the next-day effects of THC. As the study states, “The length of time an individual should wait following cannabis use before performing safety-sensitive tasks, is a critical issue.” Some government agencies and experts recommend individuals avoid performing safety-sensitive tasks for at least 24 hours. It should not surprise you to learn that the data suggests a much shorter impairment window.
During our conversation, we discuss:
- The different types of studies the authors reviewed and the criteria they used to evaluate them
- The different tests administered to measure impairment
- How next-day effects of THC compare to acute effects
- How next-day effects are different in medicinal cannabis patients vs recreational users
- What methods are available to determine THC impairment in drivers
- What is a reasonable impairment window for THC
Additional Resources
- The “Next Day” Effects of Cannabis Use: A Systematic Review - liebertpub.com/doi/10.1089/can.2022.0185
- Determining the magnitude and duration of acute Δ9-tetrahydrocannabinol (Δ9-THC)-induced driving and cognitive impairment: A systematic and meta-analytic review - sciencedirect.com/science/article/pii/S0149763421000178?via%3Dihub#!
- Lambert Initiative for Cannabinoid Therapeutics - https://www.sydney.edu.au/lambert/
- Review the Podcast! - podcasts.apple.com/tt/podcast/cannmed-coffee-talk/id1504218804
- CannMed Archive - cannmedevents.com/cannmed-video-archives
- CannMed Community Board [Facebook Group] - facebook.com/groups/cannmedcommunity
Nat and his team have been supplying high-quality cannabis seeds to growers since 2001. In 2018 they hosted the World’s Largest Phenotype Hunt, teaming with local farmers, industry experts, and top researchers. We talked about the Mega Phenotype Project as well as Nat’s process for breeding consistent and reproducible cannabis seeds.
Topics include:
- The Phenotype Rating Sheet used to evaluate plants
- The process of creating stable, pure-bred lines
- Why Humboldt Seed Company chooses to sell pure-bred lines
- Benefits of growing from seed rather than clone
- Benefits of autoflower varieties and common misconceptions
- The importance of legacy growers collaborating with academics and researchers
Danielle and her colleagues recently published a systematic review of 20 studies that examine the next-day effects of THC. As the study states, “The length of time an individual should wait following cannabis use before performing safety-sensitive tasks, is a critical issue.” Some government agencies and experts recommend individuals avoid performing safety-sensitive tasks for at least 24 hours. It should not surprise you to learn that the data suggests a much shorter impairment window.
During our conversation, we discuss:
- The different types of studies the authors reviewed and the criteria they used to evaluate them
- The different tests administered to measure impairment
- How next-day effects of THC compare to acute effects
- How next-day effects are different in medicinal cannabis patients vs recreational users
- What methods are available to determine THC impairment in drivers
- What is a reasonable impairment window for THC
Additional Resources
- The “Next Day” Effects of Cannabis Use: A Systematic Review - liebertpub.com/doi/10.1089/can.2022.0185
- Determining the magnitude and duration of acute Δ9-tetrahydrocannabinol (Δ9-THC)-induced driving and cognitive impairment: A systematic and meta-analytic review - sciencedirect.com/science/article/pii/S0149763421000178?via%3Dihub#!
- Lambert Initiative for Cannabinoid Therapeutics - https://www.sydney.edu.au/lambert/
- Review the Podcast! - podcasts.apple.com/tt/podcast/cannmed-coffee-talk/id1504218804
- CannMed Archive - cannmedevents.com/cannmed-video-archives
- CannMed Community Board [Facebook Group] - facebook.com/groups/cannmedcommunity
Allow us to introduce you to the CannMed 24 Innovation and Investment Summit, an exclusive experience of discovery, development, and networking with innovators from around the world. Since 2016, CannMed has regularly featured some of the greatest minds in medicinal plant medicine, cultivation, and safety testing. It is the most sought-after forum in which to announce the latest research and technologies while networking with current and prospective customers.
In this supercharged environment, CannMed 24 gathers stakeholders from across the industry, along with leaders from financial institutions who come together to forge enduring partnerships.
Learn more at cannmedevents.com
His team just published the results of a 3-year study that identified several factors related to growing, drying, and trimming cannabis that have a direct affect on Yeast and Mold levels. This is important because when growers fail for microbial testing, yeast and mold is most often the reason. So if you are a grower who has struggled with total yeast and mold, perhaps these findings can help you get back on track. I’ve put a link to the paper in the show description, and if you are watching on YouTube, I have added several figures and images from the paper throughout the conversation.
Thanks to This Episode's Sponsor: Agilent Technologies.
Whether you manufacture or test cannabis, you face the challenge of delivering high-quality products, increasing sample volume, and meeting emerging regulations. Agilent offers best-in-class cannabis and hemp analysis solutions featuring robust instruments, software, services, and consumables. Their team of experts can develop, implement, and optimize methods to get you up and running quickly.
Learn more at agilent.com
Additional Resources
- Total yeast and mold levels in high THC-containing cannabis (Cannabis sativa L.) inflorescences are influenced by genotype, environment, and pre-and post-harvest handling practices
- frontiersin.org/articles/10.3389/fmicb.2023.1192035/full
- 5 Factors Causing Cannabis to Fail Total Yeast and Mold - medicinalgenomics.com/5-factors-causing-cannabis-to-fail-total-yeast-and-mold
- Review the Podcast! - podcasts.apple.com/tt/podcast/cannmed-coffee-talk/id1504218804
- CannMed Archive - cannmedevents.com/cannmed-video-archives
- CannMed Community Board [Facebook Group] - facebook.com/groups/cannmedcommunity
His team just published the results of a 3-year study that identified several factors related to growing, drying, and trimming cannabis that have a direct affect on Yeast and Mold levels. This is important because when growers fail for microbial testing, yeast and mold is most often the reason. So if you are a grower who has struggled with total yeast and mold, perhaps these findings can help you get back on track. I’ve put a link to the paper in the show description, and if you are watching on YouTube, I have added several figures and images from the paper throughout the conversation.
Thanks to This Episode's Sponsor: Agilent Technologies.
Whether you manufacture or test cannabis, you face the challenge of delivering high-quality products, increasing sample volume, and meeting emerging regulations. Agilent offers best-in-class cannabis and hemp analysis solutions featuring robust instruments, software, services, and consumables. Their team of experts can develop, implement, and optimize methods to get you up and running quickly.
Learn more at agilent.com
Additional Resources
- Total yeast and mold levels in high THC-containing cannabis (Cannabis sativa L.) inflorescences are influenced by genotype, environment, and pre-and post-harvest handling practices
- frontiersin.org/articles/10.3389/fmicb.2023.1192035/full
- 5 Factors Causing Cannabis to Fail Total Yeast and Mold - medicinalgenomics.com/5-factors-causing-cannabis-to-fail-total-yeast-and-mold
- Review the Podcast! - podcasts.apple.com/tt/podcast/cannmed-coffee-talk/id1504218804
- CannMed Archive - cannmedevents.com/cannmed-video-archives
- CannMed Community Board [Facebook Group] - facebook.com/groups/cannmedcommunity
His team just published the results of a 3-year study that identified several factors related to growing, drying, and trimming cannabis that have a direct affect on Yeast and Mold levels. This is important because when growers fail for microbial testing, yeast and mold is most often the reason. So if you are a grower who has struggled with total yeast and mold, perhaps these findings can help you get back on track. I’ve put a link to the paper in the show description, and if you are watching on YouTube, I have added several figures and images from the paper throughout the conversation.
We covered:
* The different species of yeast and mold that are commonly found on cannabis and which are potentially harmful to humans
* The value of TYM testing as an indicator of product safety and quality
* What is a reasonable threshold for Total Yeast and Mold
* How Cannabis genotype affects TYM levels
* Why leaf litter drives up TYM levels
* Why hang drying is a better method than wet trimming
* The drawbacks of irradiation
* And more
Thanks to This Episode's Sponsor: Agilent Technologies.
Whether you manufacture or test cannabis, you face the challenge of delivering high-quality products, increasing sample volume, and meeting emerging regulations. Agilent offers best-in-class cannabis and hemp analysis solutions featuring robust instruments, software, services, and consumables. Their team of experts can develop, implement, and optimize methods to get you up and running quickly.
Learn more at agilent.com
Additional Resources
- Total yeast and mold levels in high THC-containing cannabis (Cannabis sativa L.) inflorescences are influenced by genotype, environment, and pre-and post-harvest handling practices
- frontiersin.org/articles/10.3389/fmicb.2023.1192035/full
- 5 Factors Causing Cannabis to Fail Total Yeast and Mold - medicinalgenomics.com/5-factors-causing-cannabis-to-fail-total-yeast-and-mold
- Review the Podcast! - podcasts.apple.com/tt/podcast/cannmed-coffee-talk/id1504218804
- CannMed Archive - cannmedevents.com/cannmed-video-archives
- CannMed Community Board [Facebook Group] - facebook.com/groups/cannmedcommunity


