Thomas Seyfried, Ph.D.: Press-Pulse - A Novel Strategy for the Metabolic Management of Cancer Epigenix Foundation 2017-11-14 | 2nd Annual Conference on Nutritional Ketosis and Metabolic Therapeutics February 2017, Tampa, FLPress-Pulse: A Novel Therapeutic Strategy for the Metabolic Management of CancerPresented by: Thomas Seyfried, Ph.D.This video is for informational purposes only. It should not be taken as medical advice.
Keith Runyan, M.D.: Management of Type 1 Diabetes with a Ketogenic Diet Epigenix Foundation 2017-11-13 | 2nd Annual Conference on Nutritional Ketosis and Metabolic Therapeutics February 2017, Tampa, FLManagement of Type 1 Diabetes with a Ketogenic DietPresented by: Keith Runyan, M.D.This video is for informational purposes only. It should not be taken as medical advice.
Raffaelle Pilla, Ph.D.: Bridging the Gap Between the Lab and Patients in Italy Epigenix Foundation 2017-11-12 | 2nd Annual Conference on Nutritional Ketosis and Metabolic Therapeutics February 2017, Tampa, FLBridging the Gap Between the Lab and Patients in Italy – a Multidisciplinary ApproachPresented by: Raffaelle Pilla, Ph.D.This video is for informational purposes only. It should not be taken as medical advice.
Mary Newport, M.D.: Medium Chain Triglycerides and Ketones for Alzheimer’s and Other Disorders Epigenix Foundation 2017-11-12 | 2nd Annual Conference on Nutritional Ketosis and Metabolic Therapeutics February 2017, Tampa, FLMedium Chain Triglycerides and Ketones for Alzheimer’s and Other DisordersPresented by: Mary Newport, M.D.This video is for informational purposes only. It should not be taken as medical advice.
Susan Masino, Ph.D.: Brain Health and Homeostasis: Ketogenic Diet, Autism, and Adenosine Epigenix Foundation 2017-11-12 | 2nd Annual Conference on Nutritional Ketosis and Metabolic Therapeutics February 2017, Tampa, FLBrain Health and Homeostasis: Ketogenic Diet, Autism, and AdenosinePresented by: Susan Masino, Ph.D.This video is for informational purposes only. It should not be taken as medical advice.
Zsolt Kovács, Ph.D.: Effect of Ketone Supplementation on Absence Seizures and Anxiety in Rats Epigenix Foundation 2017-11-12 | 2nd Annual Conference on Nutritional Ketosis and Metabolic Therapeutics February 2017, Tampa, FLEffect of Ketone Supplementation on Absence Epileptic Seizures and Anxiety in the WAG/Rjj Rat ModelPresented by: Zsolt Kovács, Ph.D.This video is for informational purposes only. It should not be taken as medical advice.
Andrew Koutnik, M.S.: Cancer Cachexia: Current and Future Therapeutics Epigenix Foundation 2017-11-12 | 2nd Annual Conference on Nutritional Ketosis and Metabolic Therapeutics February 2017, Tampa, FLCancer Cachexia: Current and Future TherapeuticsPresented by: Andrew Koutnik, M.S.This video is for informational purposes only. It should not be taken as medical advice.
Andrew Scarborough, B.Sc.: Metabolic Therapies for Anaplastic Astrocytoma and Related Epilepsy Epigenix Foundation 2017-11-12 | 2nd Annual Conference on Nutritional Ketosis and Metabolic Therapeutics February 2017, Tampa, FLBeyond Ketosis: Managing Anaplastic Astrocytoma and Brain Tumor-Related Epilepsy with Metabolic Therapies – My StoryPresented by: Andrew Scarborough, B.Sc.This video is for informational purposes only. It should not be taken as medical advice.
Adrienne Scheck, Ph.D.: The Ketogenic Diet for Glioma: Fighting the Perfect Storm Epigenix Foundation 2017-11-12 | 2nd Annual Conference on Nutritional Ketosis and Metabolic Therapeutics February 2017, Tampa, FLThe Ketogenic Diet for Glioma: Fighting the Perfect StormPresented by: Adrienne Scheck, Ph.D.This video is for informational purposes only. It should not be taken as medical advice.
Brent Reynolds, Ph.D.: An Ecological Approach to Diet Based Cancer Therapies Epigenix Foundation 2017-11-12 | 2nd Annual Conference on Nutritional Ketosis and Metabolic Therapeutics February 2017, Tampa, FLAn Ecological Approach to Diet Based Cancer TherapiesPresented by: Brent Reynolds, Ph.D.This video is for informational purposes only. It should not be taken as medical advice.
Jacob Wilson, Ph.D.: Emerging Areas of Physical Performance Across Lifespan Epigenix Foundation 2017-11-12 | 2nd Annual Conference on Nutritional Ketosis and Metabolic Therapeutics February 2017, Tampa, FLEmerging Areas of Physical Performance Across LifespanPresented by: Jacob Wilson, Ph.D.This video is for informational purposes only. It should not be taken as medical advice.
Eric Westman, M.D.: Update on Ketogenic Diet for Obesity, Diabetes, and Metabolic Syndrome Epigenix Foundation 2017-11-12 | 2nd Annual Conference on Nutritional Ketosis and Metabolic Therapeutics February 2017, Tampa, FLUpdate on Ketogenic Diet for Obesity, Diabetes, and Metabolic SyndromePresented by: Eric Westman, M.D.This video is for informational purposes only. It should not be taken as medical advice.
Jeff Volek, Ph.D.: Relevance of Keto-adaptation for Augmenting Human Performance and Resilience Epigenix Foundation 2017-11-12 | 2nd Annual Conference on Nutritional Ketosis and Metabolic Therapeutics February 2017, Tampa, FLRelevance of Keto-adaptation for Augmenting Human Performance and ResiliencePresented by: Jeff Volek, Ph.D.This video is for informational purposes only. It should not be taken as medical advice.
Jeff Volek, Ph.D.: Keto-adaptation Counteracts Insulin Resistance and Reverses Type-2 Diabetes Epigenix Foundation 2017-11-12 | 2nd Annual Conference on Nutritional Ketosis and Metabolic Therapeutics February 2017, Tampa, FLKeto-adaptation Counteracts Insulin Resistance and Reverses Type-2 DiabetesPresented by: Jeff Volek, Ph.D.This video is for informational purposes only. It should not be taken as medical advice.
Balázs Györffy, M.S.: Mitochondrial Dysfunction Underlies Complement-Mediated Synapse Elimination Epigenix Foundation 2017-11-12 | 2nd Annual Conference on Nutritional Ketosis and Metabolic Therapeutics February 2017, Tampa, FLMitochondrial Dysfunction Underlies the Elimination of Synapses Mediated by the Complement SystemPresented by: Balázs Györffy, M.S.This video is for informational purposes only. It should not be taken as medical advice.
Stephanie Ciarlone, Ph.D.: Ketone Ester Supplementation in the Angelman Syndrome Mouse Model Epigenix Foundation 2017-11-12 | 2nd Annual Conference on Nutritional Ketosis and Metabolic Therapeutics February 2017, Tampa, FLKetone Ester Supplementation in the Angelman Syndrome Mouse ModelPresented by: Stephanie Ciarlone, Ph.D.This video is for informational purposes only. It should not be taken as medical advice.
Laszlo Boros, M.D.: The Illusion of Genomic Personalized Medicine Epigenix Foundation 2017-11-12 | 2nd Annual Conference on Nutritional Ketosis and Metabolic Therapeutics February 2017, Tampa, FLGenetically Claimed Metabolic Drugs: the Illusion of Genomic Personalized MedicinePresented by: Laszlo Boros, M.D.This video is for informational purposes only. It should not be taken as medical advice.
Christos Chinopoulos, M.D., Ph.D.: Mitochondrial SLP as an Energetic Bail-In Mechanism in Cancer Epigenix Foundation 2017-11-11 | 2nd Annual Conference on Nutritional Ketosis and Metabolic Therapeutics February 2017, Tampa, FLMitochondrial Substrate Level Phosphorylation as a Potential Energetic Bail-In Mechanism in CancerPresented by: Christos Chinopoulos, M.D., Ph.D.This video is for informational purposes only. It should not be taken as medical advice.
Miriam Kalamian, M.S.: Responding to Diet Saboteurs, Critics, and Skeptics Epigenix Foundation 2017-11-11 | 2nd Annual Conference on Nutritional Ketosis and Metabolic Therapeutics February 2017, Tampa, FLResponding to Diet Saboteurs, Critics, and SkepticsPresented by: Miriam Kalamian, M.S.This video is for informational purposes only. It should not be taken as medical advice.
Eugene Fine, M.D.: Ketosis and Cancer in Cells, Animals, and People Epigenix Foundation 2017-11-10 | 2nd Annual Conference on Nutritional Ketosis and Metabolic Therapeutics February 2017, Tampa, FLKetosis and Cancer in Cells, Animals, and People - A Program for Translation and PreventionPresented by: Eugene Fine, M.D.This video is for informational purposes only. It should not be taken as medical advice.
Richard Feinman, Ph.D.: Whats Really Wrong with Medical Research and How to Fix It Epigenix Foundation 2017-11-10 | 2nd Annual Conference on Nutritional Ketosis and Metabolic Therapeutics February 2017, Tampa, FLWhat's Really Wrong with Medical Research and How to Fix ItPresented by: Richard Feinman, Ph.D.This video is for informational purposes only. It should not be taken as medical advice.
Eric Kossoff, M.D. and Mackenzie Cervenka, M.D.: Ketogenic Diet Therapy for Epilepsy Across the Ages Epigenix Foundation 2017-11-10 | 2nd Annual Conference on Nutritional Ketosis and Metabolic Therapeutics February 2017, Tampa, FLKetogenic Diet Therapy for Epilepsy Across the Ages - Opportunities and Challenges Presented by: Eric Kossoff, M.D. and Mackenzie Cervenka, M.D.This video is for informational purposes only. It should not be taken as medical advice.
Beth Zupec-Kania, R.D.: Eating Ketogenically with Optimal Nutrition Epigenix Foundation 2017-11-10 | 2nd Annual Conference on Nutritional Ketosis and Metabolic Therapeutics February 2017, Tampa, FLEating Ketogenically with Optimal NutritionPresented by: Beth Zupec-Kania, R.D.This video is for informational purposes only. It should not be taken as medical advice.
Rainer Klement, Ph.D.: Fats and Physics - Adding a Ketogenic Diet to Radiation in Cancer Treatment Epigenix Foundation 2017-11-10 | 2nd Annual Conference on Nutritional Ketosis and Metabolic Therapeutics February 2017, Tampa, FLFats and Physics - Adding a Ketogenic Diet to Radiation Therapy in Cancer TreatmentPresented by: Rainer Klement, Ph.D.This video is for informational purposes only. It should not be taken as medical advice.
David Diamond, Ph.D.: Assessing the Myth that Elevated Cholesterol Causes Cardiovascular Disease Epigenix Foundation 2017-11-10 | 2nd Annual Conference on Nutritional Ketosis and Metabolic Therapeutics February 2017, Tampa, FLA Rigorous Assessment of the Myth that Elevated Serum Cholesterol Causes Cardiovascular DiseasePresented by: David Diamond, Ph.D.This video is for informational purposes only. It should not be taken as medical advice.
Patricia Daly, MS: From Patient to Practitioner: Lessons Learned and Challenges Ahead Epigenix Foundation 2017-11-10 | 2nd Annual Conference on Nutritional Ketosis and Metabolic Therapeutics February 2017, Tampa, FLFrom Patient to Practitioner: Lessons Learned and Challenges AheadPresented by: Patricia Daly, MSThis video is for informational purposes only. It should not be taken as medical advice. Dietary changes should always be implemented with the approval and supervision of a licensed medical doctor.
Angela Poff, Ph.D.: Current Evidence and Questions on the Ketogenic Diet and Cancer in 2017 Epigenix Foundation 2017-11-10 | 2nd Annual Conference on Nutritional Ketosis and Metabolic Therapeutics February 2017, Tampa, FLWhere are we in 2017? Current Evidence and Questions on the Ketogenic Diet and CancerPresented by: Angela Poff, Ph.D.The science being presented is in the investigatory stage and has not been fully tested in human clinical studies. Angela Poff is not a medical doctor and is not promoting the use of ketosis as a medical treatment. The information in this lecture is purely educational and should not be taken as medical advice. Dietary changes should always be implemented with the approval and supervision of a licensed medical doctor.
Brendan Egan, BSc, MSc, PhD: Fueling Athletic Performance: from Carbs to Ketones Epigenix Foundation 2017-11-09 | 2nd Annual Conference on Nutritional Ketosis and Metabolic Therapeutics February 2017, Tampa, FLFueling Athletic Performance: from Carbs to KetonesPresented by: Brendan Egan, BSc, MSc, PhDThis video is for informational purposes only. It should not be taken as medical advice.
Colin Champ, M.D.: Cancer Prevention through Dietary Manipulation - Tangible Takeaways Epigenix Foundation 2017-11-09 | 2nd Annual Conference on Nutritional Ketosis and Metabolic Therapeutics February 2017, Tampa, FLCancer Prevention through Dietary Manipulation - Tangible TakeawaysPresented by: Colin E. Champ, M.D.This video is for informational purposes only. It should not be taken as medical advice.
Epigenix Foundation: An Update on the Effects of Ketogenic Diets in Canine and Human Studies Epigenix Foundation 2017-11-09 | 2nd Annual Conference on Nutritional Ketosis and Metabolic Therapeutics February 2017, Tampa, FLEpigenix Foundation: An Update on the Effects of Ketogenic Diets in Canine and Human StudiesPresented by: Ron Penna; Shannon Kesl, Ph.D.; Jethro Hu, MD; Isabella Sledge, MD, MPH; John Sledge, MDThis video is for informational purposes only. It should not be taken as medical advice.
Back into the Blue - A Pro Surfers Brain Tumor Battle & the Ketogenic Diet Epigenix Foundation 2017-01-23 | In 2016, Tim Reda was diagnosed with a brain tumor at the height of his professional surfing career. For several months, Tim lost his ability to surf when he began chemo and radiation treatments. Through the support of his physician at Cedars Sinai and alongside standard of care, Tim decided to participate in Epigenix Foundation’s ketogenic diet pilot study. The progress he’s made since his diagnosis is nothing short of extraordinary. We are proud to share with you the inspiring story of how Tim Reda made it back into the blue. NOTE: This video contains the personal views and experiences of the individual(s) in the video, and does not represent any statements or claims made or implied by Epigenix or any other person, company or organization
Nutritional Ketosis & Metabolic Therapeutics Conference 2016 Epigenix Foundation 2017-01-18 | The Conference on Nutritional Ketosis and Metabolic Therapeutics brings together international experts who speak about their research involving the science of low-carbohydrate nutrition, ketogenic diets, metabolic supplementation and medications that can be used in the treatment and prevention of cancer, metabolic disorders, and neurological diseases. For more information on our 2017 event, please go to www.metabolictherapeutics.com.
Jeff Volek, PhD Discussion on Ketogenic Diet for Dyslipidemia & Metabolic Syndrome Epigenix Foundation 2016-07-15 | Jeff Volek, PhDProfessorDepartment of Human Sciences, The Ohio State UniversityJeff Volek, Ph.D. Dr. Jeff Volek is a registered dietitian and professor in the Department of Human Sciences at the Ohio State University. For the last two decades he has been performing cutting edge research elucidating how humans adapt to diets restricted in carbohydrate with a dual focus on clinical and performance applications. His work has contributed to the existing robust science of ketones and ketogenic diets, their use as a therapeutic tool to manage insulin resistance, plus their emerging potential to augment human performance and resiliency. This research indicates that that well formulated ketogenic diets result in substantial improvements in insulin resistance and the myriad of cardio-metabolic biomarkers associated with metabolic syndrome, including favorable changes in fatty acid composition and saturated fat metabolism, cholesterol and lipoprotein profiles. He has also performed seminal research on a wide range of dietary supplements (e.g., creatine, chromium, whey protein, caffeine, carnitine, HMB, etc.) that can augment performance and recovery. He has accumulated an enormous amount of laboratory and clinical data as it pertains to biomarker discovery and formulation of personalized, effective and sustainable low-carbohydrate diets. His team is currently exploring the role of nutritional ketosis induced by diet and/or supplements to: 1) reverse type-2 diabetes, 2) alter gut microbiota, 3) favorable impact tumor metabolism and health outcomes in women with advanced breast cancer, and 4) extend human physical and cognitive capabilities in elite athletes and military personnel. Dr. Volek has secured several million dollars in research funds from federal sources, industry, and foundations. He has been invited to lecture on his research nearly 200 times at scientific and industry conferences in a dozen countries. His scholarly work includes 300+ peer-reviewed scientific manuscripts and five books, including a New York Times Best Seller.
David Ludwig, MD, PhD Which Comes First: Overeating or Obesity? Epigenix Foundation 2016-07-15 | David Ludwig, MD, PhDProfessor of Pediatrics: Harvard Medical SchoolProfessor of Nutrition: Harvard School of Public HealthDavid Ludwig, M.D., Ph.D. David S. Ludwig, MD, PhD is a practicing endocrinologist and researcher at Boston Children’s Hospital. He holds the rank of Professor of Pediatrics at Harvard Medical School and Professor of Nutrition at Harvard School of Public Health. Dr Ludwig is Founding Director of the Optimal Weight for Life (OWL) program at Children’s Hospital, one of the country’s oldest and largest multidisciplinary clinics for the care of overweight children. He also directs the New Balance Foundation Obesity Prevention Center. His research focuses on the effects of diet on hormones, metabolism and body weight. In particular, he developed a novel “low glycemic load” diet (i.e., one that decreases the surge in blood sugar after meals) for the treatment of obesity and prevention of type 2 diabetes and heart disease. Dr. Ludwig is Principal Investigator on numerous grants from the National Institutes of Health, has published over 150 scientific articles, and presently serves as Contributing Writer for JAMA. He is author of the forthcoming book, Always, Hungry? Conquer Cravings, Retrain your Fat Cells, and Lose Weight Permanently (Grand Central Publishing, January 2016).
Beth Zupec-Kania Nutritional Considerations In Managing Ketogenic Diets Epigenix Foundation 2016-07-15 | Beth Zupec-KaniaConsultant NutritionistKetogenic Therapies, LLC and The Charlie Foundation
Jacob Wilson, PhD Human Optimization: The Role of Ketogenic Dieting and Resistance Training Epigenix Foundation 2016-07-15 | Jacob Wilson, PhDAssistant ProfessorDepartment of Health Sciences and Human Performance, University of Tampa
Eric Westman, MD, MHS LCHF Treatment of Diabetes Epigenix Foundation 2016-07-15 | Eric Westman, MD, MHSAssociate Professor of Medicine: Duke UniversityDirector: Duke Lifestyle Medicine Clinic, Duke UniversityMedical Director: Duke Center for Smoking Cessation, Duke UniversityDr. Westman received his MD from the University of Wisconsin/Madison, completed an internal medicine residency and chief residency at the University of Kentucky/Lexington, and completed a General Internal Medicine Fellowship at Duke University, which included a Masters Degree in clinical research. He has been at Duke since 1990, has over 90 peer-reviewed publications, and is currently the Director of the Duke Lifestyle Medicine Clinic. He is Chairman of the Board of the Obesity Medicine Association (formerly, the American Society of Bariatric Physicians) and a Fellow of the Obesity Medicine Association and the Obesity Society. He is author of the New York Times Bestseller The New Atkins for a New You, Cholesterol Clarity, and Keto Clarity.
Keto Human Study Effects of Ketogenic Diets in Canine Cancer Epigenix Foundation 2016-07-15 | John Sledge, M.D.Dr. Sledge is a board certified orthopedic surgeon who has been practicing adult reconstructive and spinal surgery for 25 years. He is also a Founder and Medical Director of Tides Medical, an orthopedic and biologic implant company. He holds several patents for both spinal and hip implants. He has received grant support from Paralyzed Veterans of America, Orthopedic Research and Education Foundation and North American Spine Society (NASS) for his research on patient outcomes following spine and hip surgery. He was assistant chief of orthopedics at the North Shore Medical Center from 2007 to 2009 and had a clinical appointment as Assistant Professor of Orthopedic Surgery at Harvard. Dr. Sledge has conducted NIH-funded animal research for 16 years at the Harvard and University of Wisconsin primate research centers. Dr. Sledge received a medical degree from the University Of Rochester School Of Medicine. He completed the Harvard Orthopedic Residency and Mueller Fellowship programs.Ron PennaAs co-founder of Quest Nutrition and two 501c3 public charities (Ketopet Sanctuary and Epigenix Foundation), Ron has a deep passion for nutrition and its vastly underappreciated role in human health. His role as CEO of Quest Nutrition allows hims the opportunity to learn from nutrition science thought leaders and to use that information to change food manufacturing so that it impacts human health positively. A serial enterpreneur in many diverse fields including software and credit card processing, one of his current objectives is to determine the place of ketogenic diets in the treatment of cancer and enhancing human performance.
Thomas Seyfried, PhD Cancer as a Mitochondrial Metabolic Disease Epigenix Foundation 2016-07-15 | Thomas Seyfried, PhDProfessor of BiologyDepartment of Biology, Boston CollegeThomas N. Seyfried is Professor of Biology at Boston College. He received his Ph.D. in Genetics and Biochemistry from the University of Illinois, Urbana, in 1976. He did his undergraduate work at the University of New England where he recently received the distinguished Alumni Achievement Award. He also holds a Master’s degree in genetics from Illinois State University, Normal, IL. Thomas Seyfried served with distinction in the United States Army’s First Cavalry Division during the Vietnam War, and received numerous medals and commendations. He was a Postdoctoral Fellow in the Department of Neurology at the Yale University School of Medicine, and then served on the faculty as an Assistant Professor in Neurology. Other awards and honors have come from such diverse organizations as the American Oil Chemists Society, the National Institutes of Health, The American Society for Neurochemistry, and the Ketogenic Diet Special Interest Group of the American Epilepsy Society. Dr. Seyfried previously served as Chair, Scientific Advisory Committee for the National Tay-Sachs and Allied Diseases Association and presently serves on several editorial boards, including those for Nutrition & Metabolism, Neurochemical Research, the Journal of Lipid Research, and ASN Neuro. Dr. Seyfried has over 170 peer-reviewed publications and is author of the book, Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer (Wiley Press). His full list of peer-reviewed publications can be found on PubMed (http://www.ncbi.nlm.nih.gov/pubmed). The link to his professional web page follows (http://www.bc.edu/schools/cas/biology/facadmin/seyfried.html).
Mary Newport, MD Hyperketonemia for Alzheimers Disease: A Case Report Epigenix Foundation 2016-07-15 | Mary Newport, MDHospice Care PhysicianMary T. Newport, M.D. grew up in Cincinnati, Ohio, USA and was educated at Xavier University and University of Cincinnati College of Medicine, both in Cincinnati, Ohio. She is board certified in pediatrics and neonatology, and completed her training at Children’s Hospital Medical Center in Cincinnati, and Medical University Hospital in Charleston, SC. She practiced neonatology in Florida for thirty years and was founding medical director of two newborn intensive care units in the Tampa Bay area. Dr. Newport now practices at the opposite end of the spectrum, providing care for hospice patients in the Tampa Bay area of Florida. Dr. Newport is also caregiver for her husband of forty-three years, Steve, who suffers from early onset Alzheimer’s disease. They have two daughters and a grandson. She is author of Alzheimer’s Disease: What If There Was a Cure? The Story of Ketones, now in its second edition, which has been translated into French, German, and Japanese, and also author of The Coconut Oil and Low Carb Solution for Alzheimer’s, Parkinson’s and Other Diseases. Dr. Newport has been an invited speaker on this subject for symposia and conferences in the USA, Canada, France, Greece, Germany, and Japan, such as for the MCT Symposium in Tokyo, Biofach 2014, University of South Florida, the American College of Nutrition, the Institute for Human and Machine Cognition, the Fellowship in Anti-Aging and Regenerative Medicine, the International College of Integrative Medicine, Weston A. Price Foundation, and other medical and nutrition-related conferences. She has also given numerous lectures for university students and for the public.
Susan Masino, PhD The Role of Adenosine in the Ketogenic Diet for Epilepsy Epigenix Foundation 2016-07-15 | Susan Masino, PhDVernon Roosa Professor of Applied ScienceTrinity CollegeSusan Masino, Ph.D. Dr. Susan Masino is the Vernon Roosa Professor of Applied Science and Professor of Psychology and Neuroscience at Trinity College. Her laboratory uses electrophysiology, behavior and pharmacology to understand the dynamic regulation of brain activity. Her research interests span among metabolism, health and disease, and the role of adenosine in ketogenic diet therapy is a major focus. In addition to her research, Dr. Masino is dedicated to educational, environmental and public policy issues affecting brain health.
Richard Feinman, PhD Ketogenic Diets and Diabetes Epigenix Foundation 2016-07-15 | Richard Feinman, PhDProfessorSUNY Downstate Medical Center
David Diamond, PhD Dietary Sense and Nonsense in the War on Saturated Fat Epigenix Foundation 2016-07-15 | David Diamond, PhDProfessorDepartment of Psychology, University of South Florida
Stephanie Ciarlone, MS Treatment of an Angelman syndrome mouse model with a ketone ester Epigenix Foundation 2016-07-15 | Stephanie Ciarlone, MS Stephanie Ciarlone is a Graduate Research Assistant in the Department of Molecular Pharmacology and Physiology at the University of South Florida (USF). She holds a Bachelor’s degree in Biology, Psychology, and Health Sciences from Guilford College in Greensboro, NC, and a Master’s degree in Medical Sciences from USF. During her time as a graduate student she has served on the Executive Board of the Association for Medical Sciences Graduate Students from 2012 – 2015, holding the position of Vice President during the 2014 – 2015 academic year. She is currently completing her PhD in the laboratory of Dr. Edwin Weeber, where her research focuses on therapeutic options for Angelman syndrome with an emphasis on seizure treatment. Her findings have been presented at the annual Society for Neuroscience conference, where she recently received the 2015 SFN Trainee Professional Development Award.
Adam Hartman, M.D. Mechanisms of Anti-Epileptic Efficacy of KD Epigenix Foundation 2016-06-16 | Adam Hartman, M.D. Dr. Adam Hartman received his MD from Northwestern University Medical School. After completing a residency in Pediatrics in the National Capital Uniformed Services Pediatric Residency Program, he served as a general pediatrician in the US Navy for five years (the last as division head of general pediatrics at Naval Medical Center San Diego). He completed his residency in pediatric neurology and a fellowship in clinical neurophysiology/pediatric epilepsy, both at Johns Hopkins. Now an Associate Professor at Johns Hopkins, Dr. Hartman focuses on treating children with medically intractable epilepsy. In the lab, he studies metabolism-based antiseizure treatments.
Miriam Kalamian Optimizing KD therapy to meet the diverse needs of individuals Epigenix Foundation 2016-06-16 | Miriam Kalamian, Ed.M., M.S., C.N.S. Miriam Kalamian is a nutrition consultant and educator specializing in the implementation of ketogenic therapies, primarily for individuals with cancer. She earned her Master’s in Education (EdM) from Smith College and her Master’s in Human Nutrition (MS) from Eastern Michigan University. She is board certified in nutrition by the Board for Certification of Nutrition Specialists. In 2009-2010, she developed and implemented a low-carbohydrate lifestyle intervention for children and teens (BMI 99th percentile) at the South Valley Child and Family Center in Hamilton, Montana. In 2010, she formed Dietary Therapies LLC. She has served as a resource for the MaxLove Project, a nonprofit advocacy and information group for families of children with cancer. Miriam’s current work demonstrates passion and competency in adapting ketogenic therapies to accommodate the diverse and often complex needs of individuals. Specifics include: 1) identifying and addressing relative contraindications and comorbidities that may interfere with initiating or maintaining a ketogenic diet, 2) developing a personalized plan for each individual that includes diet modifications and ketone supplementation as adjuncts to conventional and alternative therapies, and 3) problem-solving complex social, emotional and environmental issues that impede dietary compliance. Beyond cancer, Miriam integrates metabolic strategies and lifestyle modifications into a therapeutic approach that optimizes health outcomes in a broad spectrum of conditions that are currently considered intractable, including age-related, neurodegenerative and bariatric diseases. To that end, she is committed to participating in collaborations that lead to the development and dissemination of best-practice guidelines for ketogenic therapies.
Angela Poff, Ph.D. Targeting Cancer Metabolism with Hyperbaric Oxygen Epigenix Foundation 2016-06-16 | Angela Poff, Ph.D. Dr. Angela Poff is a Research Associate in the Department of Molecular Pharmacology and Physiology at the University of South Florida in Tampa, FL. She holds a Bachelor’s degree in Biochemistry and Molecular Biology from Hendrix College in Conway, AR. She completed her graduate work at the University of South Florida where she earned a Master’s degree and Ph.D. in Medical Sciences. During that time, Angela served on the Executive Board of the Association for Medical Sciences Graduate Students at USF from 2010 – 2014, serving as President of the board from 2012 – 2013. Angela worked as a postdoctoral research scholar in the Department of Molecular Pharmacology and Physiology at USF from 2014 – 2015. Her research focuses on the development and characterization of metabolic-based, non-toxic therapies for cancer and neurological disorders. She has presented her work at many national and international scientific conferences, including the Keystone Symposia on Tumor Metabolism, Federation of American Societies for Experimental Biology, and the Global Symposium on Ketogenic Therapies. Angela is passionate about teaching and worked as an adjunct professor at Hillsborough Community College in Tampa where she instructed night classes in Anatomy and Physiology during her doctoral and postdoctoral tenure. She currently works as an adjunct professor in the Department of Health Sciences and Human Performance at the University of Tampa where she teaches a Master’s course on Cellular Bioenergetics and Metabolism. In her free time, she enjoys spending time with her husband, Franklin, and her two dogs and two cats.
Brent A. Reynolds, Ph.D. The Ketogenic Diet and Targeting Cancer Stem Cells Epigenix Foundation 2016-06-16 | Brent A. Reynolds, Ph.D. attended the University of Calgary where he received his M.Sc. and Ph.D. in 1989 and 1994, respectively. While working of his Ph.D. thesis Reynolds’ discovered the existence of stem cells in the adult mammalian brain, a finding that overcame a century old dogma that the mature brain did not have the capacity to repair itself. After graduating Reynolds co-founded the first neural stem cell company (NeuroSpheres, Ltd.) where he was a Director and VP-Research. Here he developed a strong patent portfolio in the neural stem cell field developing and protecting protocols related to the application of stem cell technology in brain repair. Today, these patents and technology have been licensed to numerous biotechnology companies that are testing the efficacy in over half a dozen clinical trials for diseases such as spinal cord injury, stroke, ALS and pediatric disorders. After a brief hiatus, where Reynolds studied and practiced Chinese Medicine, he returned to industry and assisted in the development and launching of several products in the stem cell field while working in Vancouver, Canada. In 2004 Reynolds returned to academic science as a Professor at the Queensland Brain Institute at the University of Queensland in Australia where he continued to refining the application of neural stem cells for repairing the damaged brain. In 2008, Reynolds’ was recruited to the Dept. of Neurosurgery at the University of Florida and has focused his efforts on studying aggressive pediatric and adult brain cancer and developing novel translational approaches to combat this lethal disease. Working with a multidisciplinary group of scientists the team is taking the unique approach that cancer can be managed as a chronic disease by applying the principles that have been used in ecology to manage wildlife and pest populations. Based on the lessons learned over the past 80 years by ecologists, the team is focused on using multimodal low toxicity therapeutics to enforcing a stable tumor population that exists below a threshold that has any harmful effects. Reynolds has more than 70 publications including papers in Science, Nature and Cell with several manuscripts receiving over 1000 citations. In addition, he is an inventor on 18 granted US patents and numerous patent applications. Reynolds is currently an Associate Professor in the Dept. of Neurosurgery at the University of Florida, Adjunct Professor at the University of New South Wales, Sydney, Australia, an Honorary Professor at the Queensland Brain Institute, Australia and Program Director for StepAhead, Australia. NIH, NHMRC and numerous foundations have funded his lab.
Adrienne C. Scheck, PhD The Ketogenic Diet as an Adjuvant to Standard of Care Epigenix Foundation 2016-06-16 | Adrienne C. Scheck, PhD, is an Associate Professor at the Barrow Neurological Institute in Phoenix Arizona. She is also an Adjunct Professor in the School of Life Sciences at Arizona State University and an Associate Investigator in the Cancer Biology Program at the Arizona Cancer Center of the University of Arizona. Dr. Scheck received her undergraduate degree from the University of Rochester in NY and her PhD from Rensselaer Polytechnic Institute in Troy, NY. After a postdoctoral fellowship in viral oncology at the Pennsylvania State College of Medicine in Hershey, Pennsylvania she moved to Memorial Sloan-Kettering Cancer Center to study AIDS-related dementia. She began her studies of brain tumors while at Sloan-Kettering and moved to the Barrow Neurological Institute in 1989. Current work in her laboratory has 2 major goals. The first is to devise novel therapeutic regimens to improve survival and minimize side effects for patients with malignant brain tumors. To this end, her laboratory has been studying the use of the ketogenic diet (KD) for the treatment of malignant brain tumors. Their work has shown that the KD reduces the growth of malignant brain tumors through a variety of mechanisms, and it potentiates the effect of radiation and temozolomide chemotherapy. These preclinical studies have led to a clinical trial for patients with glioblastoma multiforme (www.clinicaltrials.gov NCT02046187). The second main goal of her research is to identify markers that improve on the current methods of diagnosis and prognosis for this devastating disease. In addition to her love for horses, one of Adrienne’s pet projects comes from her interest in science education. Her laboratory team includes 7-10 high school students and college undergraduates. She directs a program that places high school students in research laboratories around the Phoenix area and gives Cancer Biology lectures to area high school and college students.
Jeff Volek, Ph.D. Harnessing the Power of Fat for Performance Epigenix Foundation 2016-06-16 | Jeff Volek, Ph.D.Dr. Jeff Volek is a registered dietitian and professor in the Department of Human Sciences at the Ohio State University. For the last two decades he has been performing cutting edge research elucidating how humans adapt to diets restricted in carbohydrate with a dual focus on clinical and performance applications. His work has contributed to the existing robust science of ketones and ketogenic diets, their use as a therapeutic tool to manage insulin resistance, plus their emerging potential to augment human performance and resiliency. This research indicates that that well formulated ketogenic diets result in substantial improvements in insulin resistance and the myriad of cardio-metabolic biomarkers associated with metabolic syndrome, including favorable changes in fatty acid composition and saturated fat metabolism, cholesterol and lipoprotein profiles. He has also performed seminal research on a wide range of dietary supplements (e.g., creatine, chromium, whey protein, caffeine, carnitine, HMB, etc.) that can augment performance and recovery. He has accumulated an enormous amount of laboratory and clinical data as it pertains to biomarker discovery and formulation of personalized, effective and sustainable low-carbohydrate diets. His team is currently exploring the role of nutritional ketosis induced by diet and/or supplements to: 1) reverse type-2 diabetes, 2) alter gut microbiota, 3) favorable impact tumor metabolism and health outcomes in women with advanced breast cancer, and 4) extend human physical and cognitive capabilities in elite athletes and military personnel. Dr. Volek has secured several million dollars in research funds from federal sources, industry, and foundations. He has been invited to lecture on his research nearly 200 times at scientific and industry conferences in a dozen countries. His scholarly work includes 300+ peer-reviewed scientific manuscripts and five books, including a New York Times Best Seller.
