Prostate Cancer Research Institute
A Masterclass In Prostate Cancer Pathology 2026 | Jonathan Epstein, MD & Mark Moyad, MD, MPH #PCRI
updated
For more information, visit pcri.org
1:02 The DIY manual for combating Prostate Cancer series
7:57 QR code for DIY Combat Manual for Beating Prostate Cancer Videos
9:07 The different types of Prostate Cancer - Local, Focal, Zonal, Diffuse
11:03 Metastatic Spread of Prostate Cancer
12:47 Clonal Model for Cancer Progression
13:52 Heterogeneous Model for Cancer Progression
15:01 Immunotherapy
16:24 Systemic Treatments 2024
17:50 Directed Therapies 2024
19:18 Regular and Comprehensive Follow Up is Key
21:42 Live Discussion - Fact or Fiction
23:58 Stage 4 Prostate Cancer = "Put your affairs in order?"
31:00 The higher the PSA the more aggressive the cancer
35:40 If my PSA has been undetectable or not moving for years is everything ok?
38:17 Should I ask for a second opinion?
43:23 When an insurance company says "no" is there anything I can do?
54:22 If you've had radiation treatment once can you have it again?
56:57 How many people receive spot radiation and later another spot radiation?
1:01:16 With radiation targeting spots is it better for spots close together or spread out?
1:02:32 With reoccurrence what about other treatments other than radiation?
1:05:56 Chemotherapy is rarely needed because of too many side effects? True of False?
1:10:35 How long are you on chemotherapy?
1:12:54 Does chemo therapy work against mutated cancer cells?
1:14:39 Is chemotherapy good for low and high volume disease?
1:20:08 In the era of PET imaging disease is being seen earlier
1:21:10 A lot of times the things you see in a scan aren't what needs to be worried about
1:21:40 Will Pluvicto get FDA approval for castrate sensitive prostate cancer?
1:25:54 Actinium-225 radioligand therapy possible approval in the next 3 years?
1:33:33 As you get older recovery becomes as important as the actual physical activity
1:34:20 Is Provenge the only approved immune therapy for castrate resistant prostate cancer?
1:35:47 Genetic testing may reveal enough mutations for good response to immune therapy
1:41:32 Melanoma, renal cell carcinoma, bladder cancer, have highest level of mutations
1:43:27 One liquid biopsy is better than no liquid biopsy?
1:47:58 Is PSMA PET/CT scan better than any other type of PET/CT scan?
1:50:30 10-20% of patients will have forms of disease that cannot be seen on PSMA PET scan
1:52:35 Top 5 slide topics
Don't know your stage? Take the quiz: visit http://www.prostatecancerstaging.org
To learn more about prostate cancer, visit http://www.pcri.org
Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: pcri.org/join
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
For more information, visit pcri.org
0:58 Genetics 101: Germline vs Somatic Mutations
5:04 Germline Genetic Assessment: It Takes Three
11:26 Single Nucleotide Polymorphisms (SNP's) and Prostate Cancer
13:08 What is a Genetic Risk Score (GRS)?
15:21 A Genetic Risk Score is More Informative than Family History
17:07 Benefits of Genetic Assessment in Prostate Cancer
19:30 Four Different Benefits of Germline Genetic Testing
19:45 Statistical Evidence for Guideline-recommended Genes
22:40 Genetic Risk Score (GRS)
23:28 Utility of Genetic Risk Score
25:13 Access prognosis for localized prostate cancer patients
26:18 Monogenic Genes for Prostate Cancer Progression
27:24 Mutation Carriers and Prostate Cancer Progression
29:08 Genetic Risk Score and Active Surveillance
30:30 Genetic factors associated with prostate cancer conversion from AS to treatment
32:09 Recommends therapeutic responses for advanced prostate cancer patients
32:40 Monogenetic Genes for PARPi
35:16 Monogenetic Genes for Prostate Cancer Response to ADT
37:00 Summary
38:36 What is New in the Field of Germline Genetic Testing?
41:32 Risks of Complications Among All Men with Prostate Cancer
43:38 Comparison of CVD Risk: Metastatic PC vs Localized PC
45:33 Comparison of Osteoporosis Risk: Metastatic PC vs Localized PC
46:41 Comparison of Depression Risk: Metastatic PC vs Localized PC
47:30 Comparison of Genetic Risk of Depression Among Men with Metastatic PC
1:00:16 Two types of genetic testing - Germline and Somatic
1:01:57 BRCA 2 mutation found on Somatic test- does the family need to be tested?
1:05:40 BRCA 2 mutation found on Somatic test - should you get a germline test?
1:08:38 60% of patients who don't meet insurance family history criteria will harbor a mutation
1:10:47 Most companies charge $249 or less for germline test
1:11:43 When would I know to get these tests?
1:15:50 Is a Polygenic Risk Score (PRS) recommended?
1:18:00 What critics are saying
1:20:33 Is PRS being used for Active Surveillance patients?
1:21:03 What does family history really mean?
1:26:53 Why aren't all men on active surveillance tested for BRCA mutations?
1:35:46 NCCN Germline Testing Guidelines
1:37:57 Obstacles to Genetic Testing
1:42:12 Lynch Syndrome
1:48:51 Does a heart healthy lifestyle change genes and lower/eliminate lethal PCa risk?
1:53:45 Is the PRS test ready for primetime?
1:54:31 What does "Gene variation of unknown significance" mean?
1:56:58 What are the drawbacks of Over The Counter testing?
2:00:48 Liquid biopsy - what are the pitfalls?
2:04:20 Artificial Intelligence - what is it's impact?
2:07:12 Final thoughts
Don't know your stage? Take the quiz: visit http://www.prostatecancerstaging.org
To learn more about prostate cancer, visit http://www.pcri.org
Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: pcri.org/join
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
For more information, visit pcri.org
0:22 What is the difference between a "genetic" and a "genomic" test?
1:12 How important is genetic or genomic testing to the average prostate cancer patient?
3:31 Do 5% of people have a BRCA mutation?
3:42 Should all prostate cancer patients test to see if they have a BRCA mutation?
5:09 What are "somatic" and "germline" testing?
5:56 What tests are most often used to check for BRCA mutation, and when?
7:40 Why is that patients on active surveillance are so unlikely to die from prostate cancer?
8:21 In what other contexts are genetic tests useful for prostate cancer patients?
10:14 What are the usual next steps after a patient gets their genetic test results?
10:45 How can patients best understand the results of their genetic test?
12:19 Are genetic tests usually covered by insurance and Medicare?
12:34 Is it a matter of all men should be tested?
14:01 How impactful are genetic tests on the average patient's treatment plan?
15:08 Alex's conclusions
16:39 If you need more information
Don't know your stage? Take the quiz: visit http://www.prostatecancerstaging.org
To learn more about prostate cancer, visit http://www.pcri.org
Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: pcri.org/join
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
Donate to PCRI: pcri.org/donate
Timestamps provided by viewer David Yost. (Thank you, David!)
00:19:55 Prostate Imaging — Steven Raman, MD
02:38:49 Genetic & Germline Testing — Brian Helfand, MD
04:50:55 Fact or Fiction: Advanced Prostate Cancer Treatments Q&A Session — Eugene Kwon, MD + Mark Moyad, MD
06:55:36 Extended Q+A — Mark Moyad, MD + Mark Scholz, MD
09:03:02 Closing Remarks — Alex Scholz
RSVP FOR OUR NEXT SEPTEMBER PROSTATE CANCER PATIENT CONFERENCE HERE: pcri.org/2024-conference
The 2024 Moyad + Scholz Mid-Year Update is a one-day online educational event for prostate cancer patients and caregivers. Join other patients and caregivers who will be attending from across the US and internationally. This year will be the 9th annual mid-year conference, and we are proud to welcome a distinguished faculty. This virtual conference will feature a wide range of expert speakers presenting the latest research and advances in prostate cancer treatments, imaging, and side effects. Our helpline will be available to answer questions. We welcome all patients, caregivers, advocates, and healthcare professionals interested in learning about prostate cancer. Overall, the Moyad + Scholz Mid-Year Update is a unique, full-featured educational experience for patients to access valuable resources and information and ultimately find hope and empowerment.
AGENDA
8:30am - 10:30am / Prostate Imaging / Steven Raman, MD
10:30am - 12:30pm / Genetic & Germline Testing / Brian Helfand, MD
12:30pm - 2:30pm / Fact or Fiction: Advanced Prostate Cancer Treatments Q&A Session / Eugene Kwon, MD + Mark Moyad, MD
2:30pm - 4:30pm / Extended Q+A / Mark Moyad, MD + Mark Scholz, MD
4:30pm / Closing Remarks / Alex Scholz
To learn more about prostate cancer visit http://www.pcri.org
To receive the latest updates on prostate cancer and the PCRI, sign up for our online newsletter here: pcri.org/join
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians, for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website or call our free helpline at 1 (800) 641-7274 with any questions that you have. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
The information on the Prostate Cancer Research Institute's YouTube channel is provided with the understanding that the Institute is not engaged in rendering medical advice or recommendation. The information provided in these videos should not replace consultations with qualified health care professionals to meet your individual medical needs.
Donate to PCRI: pcri.org/donate
For more information, visit pcri.org
0:30 What is hormone therapy and what are the side effects usually associated with it?
2:43 How can a loss of libido affect a prostate cancer patient?
4:10 How advisable is it for patients to use Viagra or Cialis after hormone therapy?
5:38 What is the recommended dosage for a drug like Viagra or Cialis?
6:55 How long does it take testosterone to recover following hormone therapy?
8:35 How long does it take testosterone to recover following Lupron?
9:53 Do different generations of hormone therapy have different testosterone recovery periods?
11:07 How long does it take testosterone to recover following longer course of hormone therapy?
12:04 How is testosterone recovery usually monitored?
13:48 Can testosterone replacement therapy cause cancer to grow?
16:00 When should a patient start receiving testosterone artificially after treatment?
18:08 What are types and dosages of testosterone replacement therapies?
19:00 Are there any side effects associated with testosterone replacement therapy?
20:17 How should patients and caregivers approach the return of libido?
22:34 Alex's conclusions
23:33 If you would like more information
Don't know your stage? Take the quiz: visit http://www.prostatecancerstaging.org
To learn more about prostate cancer, visit http://www.pcri.org
Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: pcri.org/join
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
Donate to PCRI: pcri.org/donate
For more information, visit pcri.org
0:39 Should hormone therapy always accompany radiation therapy?
6:24 Should age play a role in deciding whether or not to get short-term hormone therapy?
8:01 At what point does short-term hormone therapy become with the side effects?
9:55 Is it ever appropriate to delay hormone therapy after radiation?
11:32 Alex's conclusions
13:23 If you need more help
Don't know your stage? Take the quiz: visit http://www.prostatecancerstaging.org
To learn more about prostate cancer, visit http://www.pcri.org
Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: pcri.org/join
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
Visit our 2024 Moyad + Scholz Mid-Year Update webpage here: pcri.org/2024-midyear-update
The 2024 Moyad + Scholz Mid-Year Update is a one-day online educational event for prostate cancer patients and caregivers. Join other patients and caregivers who will be attending from across the US and internationally. This year will be the 9th annual mid-year conference, and we are proud to welcome a distinguished faculty. This virtual conference will feature a wide range of expert speakers presenting the latest research and advances in prostate cancer treatments, imaging, and side effects. Our helpline will be available to answer questions. We welcome all patients, caregivers, advocates, and healthcare professionals interested in learning about prostate cancer. Overall, the Moyad + Scholz Mid-Year Update is a unique, full-featured educational experience for patients to access valuable resources and information and ultimately find hope and empowerment.
AGENDA
8:30am - 10:30am / Prostate Imaging / Steven Raman, MD
10:30am - 12:30pm / Genetic & Germline Testing / Brian Helfand, MD
12:30pm - 2:30pm / Fact or Fiction: Advanced Prostate Cancer Treatments Q&A Session / Eugene Kwon, MD + Mark Moyad, MD
2:30pm - 4:30pm / Extended Q+A / Mark Moyad, MD + Mark Scholz, MD
4:30pm / Closing Remarks / Alex Scholz
To learn more about prostate cancer visit http://www.pcri.org
To receive the latest updates on prostate cancer and the PCRI, sign up for our online newsletter here: pcri.org/join
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians, for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website or call our free helpline at 1 (800) 641-7274 with any questions that you have. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
The information on the Prostate Cancer Research Institute's YouTube channel is provided with the understanding that the Institute is not engaged in rendering medical advice or recommendation. The information provided in these videos should not replace consultations with qualified health care professionals to meet your individual medical needs.
SHOW LESS
For more information, visit pcri.org
0:49 What should recently diagnosed patient prioritize when trying to decide on treatment?
3:19 What does it mean to "still have time" in the context of advanced prostate cancer?
4:29 Where can patients go to find reliable information about their treatment options?
6:06 How should patients go about confirming the facts about their prostate cancer?
7:15 How should a patient go about narrowing down their best treatment options?
8:57 What should patients do to prioritize their own quality of life during treatment?
9:50 How can a patient know that the tools they are using to research are reliable?
11:34 How can patients be confident in their treatment choices?
13:56 How should a patient approach selecting the best practitioner for them?
15:19 What can patients do to feel more comfortable to make the best decision possible?
17:45 Alex's conclusions
20:17 If you need more help
Don't know your stage? Take the quiz: visit http://www.prostatecancerstaging.org
To learn more about prostate cancer, visit http://www.pcri.org
Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: pcri.org/join
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
For more information, visit pcri.org
0:24 How does prostate cancer metastasize invocations like the liver or the lungs?
2:04 How likely are Gleason 8 & 9 cancers likely to metastasize?
3:51 How common are liver and lung metastases in prostate cancer?
4:47 What treatments are available for liver metastases?
5:51 What side effects of liver metastases treatment should patients look to avoid?
6:47 What treatments are available for lung metastases?
8:22 Is Xofigo effective for treating non-bone metastases?
8:52 What is the usual prognosis for a prostate cancer patient with liver or lung metastases?
10:58 Alex's conclusions
12:03 If you need more help
Don't know your stage? Take the quiz: visit http://www.prostatecancerstaging.org
To learn more about prostate cancer, visit http://www.pcri.org
Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: pcri.org/join
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
Donate to PCRI: pcri.org/donate
For more information, visit pcri.org
0:52 When is it right for a patient with a stable PSA to discontinue hormone therapy?
3:36 What are the upsides to discontinuing treatment and regaining testosterone?
4:43 How can a patient feel safe from recurrence after discontinuing hormone therapy?
8:03 How soon after promising treatment response should a treatment be discontinued?
9:42 How effective is treating a metastasis with spot radiation and forgoing hormone therapy?
10:52 At what PSA level would a patient be urged to go back on treatment?
11:26 Is testosterone replacement available to patients with stable PSA's following treatment?
13:21 How can patients navigate the decision to end treatment with their physician/caregiver?
14:19 Alex's conclusions
Don't know your stage? Take the quiz: visit http://www.prostatecancerstaging.org
To learn more about prostate cancer, visit http://www.pcri.org
Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: pcri.org/join
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
For more information, visit pcri.org
0:33 How does prostate cancer metastasize to the bones?
2:09 Can a patient go from having bone metastases to a full remission?
4:55 What options, other than spot radiation, are there for treating bone metastases?
7:52 Is hormone therapy always a necessity for those with bone metastases?
9:02 How flexible is the timeframe for a typical course of hormone therapy?
11:00 How do treatments like Xgeva work to treat bone metastases?
12:23 What treatment options are there after first/second-generation hormone therapies?
13:28 How is the effectiveness of Provenge usually tracked?
14:05 What is the next step after Provenge?
15:51 When would Xofigo be prescribed as opposed to Pluvicto?
17:18 How quickly should patients be adjusting their treatment strategies?
19:09 How well do patients usually handle the side effects of these treatments?
20:35 Alex's conclusions
21:19 If you need more help
Don't know your stage? Take the quiz: visit http://www.prostatecancerstaging.org
To learn more about prostate cancer, visit http://www.pcri.org
Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: pcri.org/join
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
#prostatecancer #pcri
youtu.be/-RVVq0uDAEE
Prostate Cancer Support Groups:
ancan.org/prostate-cancer
zerocancer.org/help-and-support/find-support-group
healthunlocked.com/advanced-prostate-cancer
Prostate Cancer Survival Statistics:
American Cancer Society Prostate Cancer 5-Year Survival Rates
cancer.org/cancer/types/prostate-cancer/detection-diagnosis-staging/survival-rates.html
Donate to PCRI: pcri.org/donate
For more information, visit pcri.org
0:58 How and why does prostate cancer metastasize in the bones?
2:51 How common are metastases in the liver and lungs?
3:45 Can bone metastases cause noticeable pain as a symptom?
5:19 How is the pain from bone metastasis usually treated?
7:47 At what point would a patient have too many metastases to undergo spot radiation?
10:13 Where can patients find the best spot radiation treatment?
11:02 How effective are modern beam radiation treatments?
13:08 How does beam radiation affect PSA for oligometastatic disease?
14:47 How is a patient's treatment progress usually monitored?
17:07 Alex's conclusions
19:05 If you need help
Don't know your stage? Take the quiz: visit http://www.prostatecancerstaging.org
To learn more about prostate cancer, visit http://www.pcri.org
Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: pcri.org/join
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
#ProstateCancer #PCRI
For more information, visit pcri.org
2:07 What is the pathology process, and what does a Gleason score mean?
4:54 How should a patient broach questions about treatment with their physician?
9:27 Should patients seek out their pathology report? Can they trust it?
11:22 Can Gleason 6 ever metastasize?
13:04 How likely is a Gleason 3+4 cancer to metastasize, vs a 4+3?
16:27 Are Gleason 8 cancers more likely to spread than Gleason 7 cancers?
17:12 How likely is metastasis with Gleason 9 cancer?
17:36 How likely is metastasis with Gleason 10 cancer?
18:14 What Gleason score is the most common in active cancer patients?
19:06 How dangerous is a cancer with a higher Gleason score?
20:59 Alex's conclusions
22:16 If you need more help
Don't know your stage? Take the quiz: visit http://www.prostatecancerstaging.org
To learn more about prostate cancer, visit http://www.pcri.org
Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: pcri.org/join
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
Donate to PCRI: pcri.org/donate
For more information, visit pcri.org
1:13 What is intermittent hormone therapy, and how does it work?
4:43 How is intermittent hormone therapy administered?
6:12 Is letting a patient's PSA rise to 2 advisable during therapy?
8:24 Is nine months a reasonable treatment period before considering a holiday?
9:12 How often is PSA checked during intermittent hormone therapy?
9:33 Does the type of therapy matter during intermittent hormone therapy?
11:13 Is intermittent hormone therapy complicated for insurance coverage?
12:00 How much do side effects usually recede during the holiday period?
13:45 How long can intermittent hormone therapy last?
14:45 Alex's conclusions
15:13 If you need help
Don't know your stage? Take the quiz: visit http://www.prostatecancerstaging.org
To learn more about prostate cancer, visit http://www.pcri.org
Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: pcri.org/join
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
Donate to PCRI: pcri.org/donate
For more information, visit pcri.org
1:02 What was the outcome of the recent EMBARK trial?
5:27 What side effects are typically related to Lupron?
6:08 Is combination therapy going to become increasingly prescribed?
7:15 Is combination therapy advisable for high Gleason scores?
8:54 Can you use any second generation hormone therapy for combination therapy?
9:58 Alex's conclusions
11:49 If you need help
Don't know your stage? Take the quiz: visit http://www.prostatecancerstaging.org
To learn more about prostate cancer, visit http://www.pcri.org
Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: pcri.org/join
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
For more information, visit pcri.org
0:23 What are lymph nodes, and where are they in the body, relative to the prostate gland?
1:49 How are different degrees of lymph node metastasis usually treated?
4:30 Is there a likelihood of metastasis associated with each Gleason score?
6:06 Can Gleason grade indicate the location of a potential metastasis?
6:46 How many metastatic lymph nodes constitutes a "serious" metastatic condition?
8:57 Is a specific form of radiation more effective for treating metastatic lymph nodes?
10:06 Could radiation potentially damage tissues near the lymph nodes during treatment?
11:22 What should a previously treated patient who discovers new metastasis do?
13:17 What should a post-surgery patient with just one abdominal metastasis do?
14:26 Can metastasis in the chest or neck lymph nodes be treated with radiation?
16:17 What differentiates lymph node metastasis from bone metastasis?
17:48 Alex's conclusions
18:20 If you need help
Don't know your stage? Take the quiz: visit http://www.prostatecancerstaging.org
To learn more about prostate cancer, visit http://www.pcri.org
Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: pcri.org/join
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
For more information, visit pcri.org
0:28 What is micrometastatic disease, and how is it relevant in prostate cancer treatment?
3:53 How has the advent of the PSMA PET scan affected treatment of micrometastatic disease?
7:17 Should every new prostate cancer patient be getting a PSMA PET scan?
9:58 What options are there for those who've already received treatment and are now monitoring?
12:18 How might a prostate cancer patient be monitored after treatment?
12:53 What "cured" mean in the context of prostate cancer?
13:45 What hormone therapy options are there for treating micrometastatic disease?
17:39 How should a patient go about communicating their treatment preferences to their doctor?
18:57 Have PSMA PET scans changed the definition of micrometastatic disease?
20:05 Alex's conclusions
21:00 If you need help
Don't know your stage? Take the quiz: visit http://www.prostatecancerstaging.org
To learn more about prostate cancer, visit http://www.pcri.org
Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: pcri.org/join
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
Watch Howard's previous interview, where he shares his advice to patients seeking Active Surveillance: youtu.be/jEJg6ZPCT8E
If you would like to nominate someone for PCRI's Harry Pinchot Award, please submit information about your nominee here: pcri.org/harry-pinchot-award-nomination
1:39 Honoring Howard Wolinsky
3:37 Howard's reaction to his nomination
4:36 Howard's story
9:17 Dr. Scholz, Dr. Moyad, Howard Wolinsky, Alex Scholz
10:35 Active Surveillance/Howard Wolinsky Club
12:49 Harry Pinchot showed the way
Don't know your stage? Take the quiz: visit http://www.prostatecancerstaging.org
To learn more about prostate cancer, visit http://www.pcri.org
Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: pcri.org/join
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
For more information, visit pcri.org
Contact our Helpline: www.pcri.org/helpline
1:02 What is PSA used for, and how is it measured?
2:36 Is PSA the only way to screen for prostate cancer?
4:53 Is there any reason to get a Digital Rectal Exam?
5:47 What is PSA density, and how large is the average prostate?
7:13 How accessible and affordable are MRI's, usually?
7:38 How should a patient approach their physician about MRI's?
8:24 What happens next if an MRI detects a potentially cancerous spot?
10:29 What constitutes a "center of excellence"?
10:56 How much does a person's PSA usually fluctuate?
12:54 Can PSA be used to monitor the effectiveness of treatments?
15:43 At what rate does prostate cancer normally develop?
17:00 Alex's conclusions
18:14 If you have questions
Don't know your stage? Take the quiz: visit http://www.prostatecancerstaging.org
To learn more about prostate cancer, visit http://www.pcri.org
Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: pcri.org/join
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
For more information, visit pcri.org
0:26 What is micro-ultrasound and how does it work?
3:09 How well does micro-ultrasound compare to 3T MRI's?
4:57 How well does micro-ultrasound compare to PSMA-PET scans?
6:03 How does micro-ultrasound fit into the realm of biopsies for prostate cancer?
7:38 Is there a chance that micro-ultrasound might one day replace MRI's?
9:03 Is micro-ultrasound usually covered by most insurance plans?
9:18 How widespread and available is micro-ultrasound?
9:53 How might micro-ultrasound affect active surveillance protocol in the future?
11:18 Alex's conclusions
12:22 If you need help
Don't know your stage? Take the quiz: visit http://www.prostatecancerstaging.org
To learn more about prostate cancer, visit http://www.pcri.org
Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: pcri.org/join
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
For more information, visit pcri.org
1:03 At what stage of prostate cancer would TULSA-PRO be most useful?
3:15 At what Gleason score is TULSA-PRO most often recommended?
4:15 How long does a usual TULSA-PRO procedure usually take to complete?
4:58 What are the most common TULSA-PRO side effects?
5:45 Is urethral scar tissue a concern when undergoing TULSA-PRO treatment?
6:50 Comparatively, how likely is TULSA-PRO to cause sexual side effects?
8:16 Does the location or quantity of tumors affect focal therapy?
10:07 How does TULSA-PRO affect PSA after treatment?
10:44 How often should PSA be checked, in addition to yearly MRI's?
11:02 What does a tumor look like on an MRI following TULSA-PRO?
11:28 Is TULSA-PRO a good option for those with metastatic disease looking to treat locally?
12:09 Are there treatments for localized cancer that work as well or better than TULSA-PRO?
14:45 Alex's conclusions
Don't know your stage? Take the quiz: visit http://www.prostatecancerstaging.org
To learn more about prostate cancer, visit http://www.pcri.org
Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: pcri.org/join
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
Donate to PCRI: pcri.org/donate
For more information, visit pcri.org
0:40: What is Gleason 6 prostate cancer?
3:40: What benefits does an MRI have over a random needle biopsy?
5:34: Does Gleason 6 metastasize?
7:10: What are the most important results of this recent study?
9:48: Are there any cases in which a random needle biopsy is necessary?
10:51: Why opt for an MRI first, instead of PSMA pet scan?
11:36: Should patients always try to get a 3T instead of a 1.5T MRI?
12:22: What are the downsides of treating Gleason 6 prostate cancer?
13:59: Alex's Conclusion
Don't know your stage? Take the quiz: visit http://www.prostatecancerstaging.org
To learn more about prostate cancer, visit http://www.pcri.org
Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: pcri.org/join
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors. #PCRI
For more information, visit pcri.org
Videos For Further Information:
PARP Inhibitors: youtu.be/61PO5NpBeWE
PSMA: youtu.be/pYfewhyUZJs
Active Surveillance: youtu.be/i8-5TlDEVGg
PROSTOX: youtu.be/kIWAv9oRD0c
Zepbound: youtu.be/ycZ2wdzU4ZU
1:08 What are the new PARP Inhibitors, Talzenna and Akegga?
2:18 How effective has PSMA been at helping patients delay chemotherapy?
5:08 What was the state of active surveillance in 2023?
5:56 What is Prostox and can it apply to spot radiation?
7:49 What was the state of Pluvicto as a treatment in 2023?
10:02 How have Zepbound and other semaglutides affected prostate cancer?
11:39 How has prostate cancer treatment been affected by all these new developments?
13:26 Alex's conclusions
Don't know your stage? Take the quiz: visit http://www.prostatecancerstaging.org
To learn more about prostate cancer, visit http://www.pcri.org
Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: pcri.org/join
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
For more information, visit aspatients.org
0:35 Diagnosed with prostate cancer in 2009 at age 57
1:26 Was the family physician involved?
2:13 What did the urologist explain?
3:15 Not typical to be referred to a counselor and support group
3:53 What type of biopsy?
4:35 What lead to decision to choice Active Surveillance?
6:22 An important discovery made at the support group meeting
7:41 How was your wife's anxiety brought down?
8:46 Value of the second support group
9:42 Watchful Waiting vs Active Surveillance
9:52 Another tool for the toolbox
11:10 First steps for Active Surveillance
11:52 What was the PSA at that time and monitoring process?
14:31 Was there a time for a second biopsy?
16:42 Did switching to Medicare make the options for selecting a doctor easier?
17:06 The importance of being your own case manager
18:35 What should a newly diagnosed patient be told?
20:23 A plan for management
21:35 Personal monitoring system
24:04 Alex's conclusions
Don't know your stage? Take the quiz: visit http://www.prostatecancerstaging.org
To learn more about prostate cancer, visit http://www.pcri.org
Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: pcri.org/join
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
For more information. visit www.pcri.org
0:48 How should patients weigh new and old treatments?
3:12 What should patients try to keep in mind when deciding on treatments?
4:42 How does prostate cancer "staging" affect treatment?
5:42 How important is it to get a second opinion on treatment?
7:06 Selection of who is going to guide you in the treatment
8:52 How can a patient know if their doctor is qualified to perform a procedure?
10:45 Addressing the "Grey Zone"
11:59 How long does it take a treatment to become proven effective?
15:28 Cure at any cost vs side effect ratio
17:13 Alex's conclusions
20:11 If you need support
Don't know your stage? Take the quiz: visit http://www.prostatecancerstaging.org
To learn more about prostate cancer, visit http://www.pcri.org
Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: pcri.org/join
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians, for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
For more information. visit www.pcri.org
0:43 Low Dose Rate (LDR) Prostate Brachytherapy
3:13 Overview
3:52 History
9:24 Why LDR Brachytherapy?
10:18 Treatment Recommendations/Patient Selection
11:41 Role of Brachytherapy by risk category
14:36 The Evolution of Prostate Brachytherapy
15:05 Pre-planned Brachytherapy
16:08 Intraoperatively Planned Brachytherapy
18:44 Real-time Intraoperatively Planned Brachytherapy
19:37 The patient experience
20:14 Post procedure:patient recovery
22:24 Toxicity and Outcomes are Operator Dependent
25:11 Outcomes: Low/favorable Intermediate risk prostate cancer
26:18 Intermediate risk prostate cancer
28:04 High risk prostate cancer
28:53 Brachytherapy boost achieves surgical PSA below 0.2
29:49 ADT role in high risk prostate cancer
32:06 Summary of Patient Outcomes
32:37 LDR Brachytherapy Toxicity and Outcomes are Operator Dependent
33:43 Brachytherapy vs other options
35:23 LDR vs EBRT
37:14 Comparing LDR Brachytherapy to External Beam Radiation
39:38 Comparing LDR Brachytherapy to Prostatectomy
42:10 Comparing LDR Brachytherapy to HDR Brachytherapy
45:07 Comparing LDR Brachytherapy to Proton Therapy
47:09 Why isn't LDR Brachytherapy more prevalent?
50:17 Final thoughts
51:38 Q & A
53:56 What is the age range of the patents you see?
56:35 Debate over surgery first vs radiation first for treatment
1:00:55 Brachytherapy Pro vs Amateur
1:04:46 Different types of seed implants
1:06:56 How many seeds?
1:08:42 How many doctors have performed high quantity of implants?
1:09:30 Where can the treatment be performed?
1:10:55 How long does treatment take?
1:11:35 What is the step by step procedure?
1:13:48 Can I have a baby after treatment?
1:14:30 Dry orgasms?
1:16:04 Who is a bad candidate for Brachytherapy?
1:20:18 How do I measure results?
1:22:43 Is there a diet or supplement I should go on?
1:24:11 How do I know that I don't have lymph node disease?
1:26:11 What about a PET/CT scan before treatment?
1:26:34 What about genetic testing?
1:28:48 How often do I follow up?
1:29:59 Do you have to deal with radiation resistant tumors?
1:30:27 How often do I take medication for side effects?
1:33:22 What about seed migration?
1:34:29 Are you doing focal therapy?
1:36:29 What about cancer just beyond the prostate?
1:38:02 What about secondary cancers?
1:38:51 Testosterone reduction after seed implant?
Don't know your stage? Take the quiz: visit http://www.prostatecancerstaging.org
To learn more about prostate cancer, visit http://www.pcri.org
Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: pcri.org/join
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians, for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
For more information, visit www.pcri.org
0:50 Is chemotherapy for prostate cancer different than chemotherapies for other cancers?
1:28 How is chemotherapy useful for prostate cancer?
2:53 What kind of patient is best suited for chemotherapy?
4:18 What its the chemotherapy process like for a prostate cancer patient?
6:29 What type of side effects often accompany chemotherapy during treatment?
8:19 How accurate is the usual media portrayal of the chemotherapy process?
9:26 Can chemotherapy cause numbness in the extremities and salivary glands?
10:54 How long do side effects generally last after chemotherapy is done?
12:07 Can fasting mitigate any of the side effects of chemotherapy?
13:32 Can lifting weights help with minimizing the side effects of chemotherapy?
14:36 Alex's conclusions
16:52 If you need more information
Don't know your stage? Take the quiz: visit http://www.prostatecancerstaging.org
To learn more about prostate cancer, visit http://www.pcri.org
Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: pcri.org/join
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
Donate to PCRI: pcri.org/donate
For more information, visit www.pcri.org
0:34 What is BPH and how are TURP's used to treat it?
1:47 Are TURP's usually go-to procedure for treating BPH?
2:30 Is scar tissue a common complication of TURP's?
3:09 What are the recommended alternatives to TURP's?
4:45 What side effects can be expected from REZUM/Urolift/iTIND?
5:56 If TURP is ineffective at first, it is advisable to try it again?
7:17 Is age a risk factor when undergoing one these procedures?
7:51 Are some BPH treatments incompatible with other prostate cancer procedures?
9:35 Alex's conclusions
Don't know your stage? Take the quiz: visit http://www.prostatecancerstaging.org
To learn more about prostate cancer, visit http://www.pcri.org
Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: pcri.org/join
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
For more information, visit www.pcri.org
0:30 What are Actinium and PSMA and how do they work?
1:17 PSMA PET Scans
1:39 Actinium-255
2:17 Does Actinium have stronger side effects than Lutetium?
3:49 Can the salivary glands be protected during treatment?
4:10 When should a patient consider Actinium?
5:46 Does Actinium have a noticeable effect on tumor size?
6:37 Is Actinium effective at treating very advanced cancer?
7:44 What advantages does Actinium have over Lutetium?
9:09 Alex's conclusions
Don't know your stage? Take the quiz: visit http://www.prostatecancerstaging.org
To learn more about prostate cancer, visit http://www.pcri.org
Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: pcri.org/join
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
Donate to PCRI: pcri.org/donate
For more information, visit www.pcri.org
1:48 Diagnosis of Prostate Cancer is the tip of the iceberg
2:41 Can we prevent Prostate Cancer?
2:54 What about diet?
3:59 Should men start getting MRI's of their prostate starting at age 40?
5:30 How likely is the average person to be diagnosed with low-grade prostate cancer?
5:55 Is susceptibility to prostate cancer genetically heritable?
6:34 Can frequent ejaculation have an effect on one's chances of getting prostate cancer?
8:38 Alex's conclusions
10:40 If you need more information
Don't know your stage? Take the quiz: visit http://www.prostatecancerstaging.org
To learn more about prostate cancer, visit http://www.pcri.org
Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: pcri.org/join
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
Subscribe to our YouTube Channel!
#ProstateCancer #Prostate #PCRI
For more information, visit www.pcri.org
0:25 What should patients with a negative PSMA but rising PSA do?
2:06 What was the character of the cancer before treatment?
3:06 Many factors influence whether to have treatment or not
4:06 Can an Axumin scan pick up a cancer that a PSMA scan may have missed?
5:42 What is a Choline C-11 PET Scan?
6:21 What is a FDG PET Scan?
6:37 Should MRI scans usually be administered before PSMA scans?
7:50 Is jumping right to hormone therapy instead of imaging an option?
8:50 How should patients navigate the imaging process with their physician?
10:24 How often should post-surgery patients be monitoring their PSA?
11:17 Alex's conclusions
13:45 If you need more information
Don't know your stage? Take the quiz: visit http://www.prostatecancerstaging.org
To learn more about prostate cancer, visit http://www.pcri.org
Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: pcri.org/join
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
For more information. visit www.pcri.org
0:45 If your having elective surgery you need to stop weight loss drugs
1:44 Why not get medication to help with your weight?
2:45 One of the biggest catches
3:05 The SELECT Trial
4:47 Diet and exercise
5:42 Are these new medicines the real deal?
6:35 These medications are for people who need immediate weight loss
Don't know your stage? Take the quiz: visit http://www.prostatecancerstaging.org
To learn more about prostate cancer, visit http://www.pcri.org
Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: pcri.org/join
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
For more information. visit www.pcri.org
1:44 "It takes 50 years to get a wrong idea out of medicine"
2:25 Adrenaline is the most potent anti-erection chemical
3:35 Achieving optimal outcomes
4:04 The word cancer is scary
5:45 Barriers to optimal sexual outcomes
10:45 Realistic expectations
13:09 Cause of ED
21:28 Radical Prostatectomy things to remember
25:50 RP-Sexual Incontinence
27:22 RP-Penile Length Loss
28:56 Radiation
32:21 ADT
35:38 Obsessive Oncocentricity - absolute focus on cancer outcome
37:08 Is Active Surveillance an option?
37:47 How important is your future sex life?
38:49 What is "erectile function preservation/recovery"
39:58 Get realistic expectations
43:53 If you have ED before treatment
44:36 Open vs. Robotic surgery outcomes
45:20 Physical experience key to success
47:25 Penile Rehabilitation
49:43 Sexual function outcomes between different modalities
51:13 Testosterone deficient with ADT
52:08 Erection pills
55:14 Penile injection
56:50 Triple therapy
57:07 Testosterone levels
58:51 Restorative therapies
59:57 Words of advice for partners
1:00:51 Q & A with Dr. Moyad
1:05:58 Journal of Sexual Medicine
1:06:58 Saving your sex life
1:08:55 Sexual Medicine Society of North America
1:10:55 Being careful as a consumer using the internet as a resource
1:11:29 Lifestyles
1:12:28 What's good for your heart is good for your penis
1:14:41 ED is a harbinger of cardiovascular disease
1:16:55 Adrenaline is the worlds most potent anti-erection chemical
1:18:26 Alcohol
1:20:18 Marijuana
1:21:39 Over the counter space
1:28:08 Penile rehabilaitation
1:40:40 Sex drive issues
1:42:42 Neurovascular bundles
1:49:04 Shockwave therapy
1:53:01 Testosterone replacement
1:58:03 Perone's disease
Don't know your stage? Take the quiz: visit http://www.prostatecancerstaging.org
To learn more about prostate cancer, visit http://www.pcri.org
Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: pcri.org/join
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians, for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
For more information, visit www.pcri.org
0:34 What are the different stages of prostate cancer?
2:26 What are the different staging systems?
4:25 Does staging affect treatment choices?
5:06 How common is it for patients to prioritize quality of life during treatment?
7:33 How well known are the stages among prostate cancer patients?
8:46 What is low/intermediate/high-risk prostate cancer?
12:37 Alex's conclusions
14:14 If you need more information
Don't know your stage? Take the quiz: visit http://www.prostatecancerstaging.org
To learn more about prostate cancer, visit http://www.pcri.org
Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: pcri.org/join
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
For more information, visit www.pcri.org
5:17 The Number of people on Active Surveillance is increasing?
5:37 Proper to diagnose someone with an insignificant tumor?
5:53 Do I have "cancer"?
6:28 What is cancer?
8:05 PSA is the best screening biomarker in the history of oncology if used well
8:22 Newer screening practices
9:33 Does this mean Grade Group 1, 3+3, Dr. Cooperberg says not cancer?
10:34 GG1 is not a normal finding, but A.S. is recommended
11:58 Continuum of Biology
12:57 Arbitrary line drawn for cancer
13:45 What if we don't call it cancer?
14:49 Why the largest PSA screening trial failed
19:25 Should men go for PSA screening?
20:57 Median PSA is 0.7 between 45 and 50
21:22 If it's under 1.0, you're done
22:30 PSA values vary
23:23 What does act on PSA mean?
24:50 Liquid tests
25:54 Why not have everyone get an MRI?
26:23 What inter-observer variability exists with MRI's?
32:27 Cooperberg screening policy
33:59 DRE (Digital Rectal Exam)
40:26 How should a man choose his localized treatment?
43:15 Is there an age limit for Active Surveillance?
45:45 Mental health considerations
49:31 Confirmatory biopsy
52:01 Why can't everyone diagnosed get a BRCA/Genetic test?
56:10 What do we do differently now we know you have a BRCA mutation?
1:00:25 What about Pathology?
1:01:10 Sub-types of Pattern 4
1:02:38 Cribriform patterns
1:04:14 All GS 3+4 is not created equal
1:05:25 Is PSA density of 0.15 a valid cutoff for Active Surveillance?
1:05:50 Intraductal/large cribriform patterns for Active Surveillance?
1:06:54 Cancer is driven by the worst corner of it
1:08:06 Most Gleason 7's sent for genomic test
1:08:34 Intraductal worst pattern followed by cribriform
1:09:24 DRE's for Active Surveillance?
1:09:48 How often for PSA's/MRI's?
1:10:26 Active Surveillance 2023 (one opinion)
1:12:59 How do you choose your urologist?
1:15:00 Do PSA kinetics matter?
1:16:05 MEAL trial
1:18:22 What about exercise?
1:19:35 What about testosterone replacement therapy?
1:21:32 What about the two types of PSA tests?
Don't know your stage? Take the quiz: visit http://www.prostatecancerstaging.org
To learn more about prostate cancer, visit http://www.pcri.org
Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: pcri.org/join
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
For more information. visit www.pcri.org
0:41 What is prostate cancer treatment like for younger patients?
2:49 What non-surgical options would a Gleason 8-9 patient generally have?
4:16 What forms of radiation treatments have the best clinical outcomes?
5:11 What side effects do brachytherapy and hormone therapy have?
6:15 How does the new PSMA scan affect treatment for younger patients?
6:55 How can younger patients treat drug-resistant erectile dysfunction?
7:42 Can radiation treatment cause urinary side effects?
8:51 What cure rates do modern forms of radiation treatment have?
10:18 Can younger patients get prescribed early chemotherapy?
11:37 How should younger patients prioritize quality of life when deciding treatment?
13:11 Alex's conclusions
Don't know your stage? Take the quiz: visit http://www.prostatecancerstaging.org
To learn more about prostate cancer, visit http://www.pcri.org
Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: pcri.org/join
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians, for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
eventbrite.com/e/prostate-cancer-abcs-fl-a-free-conference-for-patients-caregivers-tickets-636124083257?aff=erelexpmlt
Donate to Cancer ABCs: cancerabcs.org/new-page-2
Jan's Story | Her Husband's PSA Was 7,000 | youtu.be/zOGvCNxDO-8
PCRI's CEO, Alex Scholz, interviews Cancer ABC's Executive Vice President, Jan Manarite, about the ins and outs of planning your doctor's visits, how to ask the right questions, who should you talk to, and much more.
Visit Cancer ABC's website cancerabcs.org.
Cancer ABC's is a non-profit organization in New York City whose mission is to provide education and other resources that bring tangible improvements in the lives of cancer patients. Although the organization provides support to people afflicted by all types of cancer, it has always had a special focus on prostate cancer.
Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: pcri.org/join
Don’t know your stage? Take the quiz: Visit http://www.prostatecancerstaging.org
To learn more about prostate cancer visit http://www.pcri.org
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians, for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
The information on the Prostate Cancer Research Institute's YouTube channel is provided with the understanding that the Institute is not engaged in rendering medical advice or recommendation. The information provided in these videos should not replace consultations with qualified health care professionals to meet your individual medical needs.
#ProstateCancer #CancerABCs #PCRI


