The State of Apps with Olivia Moore a16z 2023-02-09 | A few weeks ago, Apple released a stunning statistic: they’ve paid developers over $320B — yes, billion! — since the launch of the App Store in 2008, highlighting the cast opportunity in the marketplace.And around the same time, a16z Consumer Partner, Olivia Moore, compiled a list of the top apps across the US app store throughout 2022.In this episode, you’ll get to hear which apps made it to the top and what they have in common. Hint: the big winners were in social, but perhaps a new wave of social apps!We also get the scoop on what it really takes to not just hit #1, but stay there. This episode highlights numerous surprising examples ranging from a new-age Beanie Baby app, a viral talking dog, an app from 2012 that finally broke the top 10, and the Chinese app that’s been at #1 for a majority of 2023, and it’s not TIkTok!There are endless learnings about how new founders can take advantage of these opportunities.Timestamps:00:00 - Top apps in 202203:23 - A new era of social?06:55 - Hitting #108:57 - Staying on top10:43 - Building a sticky product13:29 - Growing an app in 202314:57 - User-generated growth17:07 - 2022 category winners20:00 - Anonymous social21:37 - Early monetization25:45 - Monetization trends30:27 - Leveraging platform shifts34:58 - Surprising hits37:21 - Looking toward 202339:09 - Invisible AI products41:19 - Limiting virality44:43 - Vertical social networks48:16 - When digital goes physical51:19 - TikTok growth53:01 - Geographic trends55:33 - A decade old app59:58 - App challengeResources: * Follow Olivia on Twitter: twitter.com/omooretweets * Olivia's 2022 analysis: twitter.com/omooretweets/status/1605983056682045440 * Olivia's 2021 analysis: twitter.com/omooretweets/status/1483482099562602500 * Justine’s Boating app commentary: twitter.com/venturetwins/status/1616121691830390784 * Olivia’s Tinder subscription commentary: twitter.com/omooretweets/status/1616480480546942976 Apps mentioned: * BeReal: apps.apple.com/us/app/bereal-your-friends-for-real/id1459645446 * TikTok: apps.apple.com/us/app/tiktok/id835599320 * Gas App: apps.apple.com/us/app/gas/id1641791746 * Talking Ben the Dog: apps.apple.com/us/app/talking-ben-the-dog/id416345319 * Argo Boating Navigation: apps.apple.com/us/app/argo-boating-navigation/id1463869636 * NoteIt: apps.apple.com/us/app/noteit-widget-get-it-now/id1570369625 * Locket Widget: apps.apple.com/us/app/locket-widget/id1600525061 * LiveIn: apps.apple.com/us/app/livein-share-your-moment/id1606780589 * Slay: apps.apple.com/de/app/slay-komplimente-umfragen/id1645858841 * Lensa AI: apps.apple.com/us/app/lensa-photo-editing/id1436732536* Starlink: apps.apple.com/us/app/starlink/id1537177988* NOAA Weather: apps.apple.com/us/app/noaa-weather/id436760574 * Stardust Period Tracker: apps.apple.com/us/app/stardust-period-tracker/id1495829322 * Temu: apps.apple.com/us/app/temu-team-up-price-down/id1641486558 * SquadApp: apps.apple.com/us/app/squadapp-collection-database/id1623120952 * TravelBoast: apps.apple.com/us/app/travelboast-my-journey-routes/id1476504378 * Subway Surfers: apps.apple.com/us/app/subway-surfers/id512939461Stay Updated: Find a16z on Twitter: twitter.com/a16z Find a16z on LinkedIn: linkedin.com/company/a16z Subscribe on your favorite podcast app: a16z.simplecast.com Follow our host: twitter.com/stephsmithio Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. For more details please see a16z.com/disclosures.
How to Build a Thriving AI Ecosystem with Lisa Su, CEO of AMD a16z 2024-10-17 | High-performance compute is the bedrock of generative AI, and if there’s anyone who knows about high-performance chips, it’s AMD CEO Lisa Su. In this wide-ranging conversation with a16z Operating Partner Bob Swan—himself formerly CEO of Intel—Lisa lays out her vision for the evolution of compute within the AI ecosystem, touching not only on raw power and the continuation of Moore’s Law, but also how AMD will support “the right compute for each form factor” for a wider ranges of real-world gen AI use cases. Lisa also shares her perspective on the state of chip manufacturing, how AMD matches their R&D cycles to fast-moving industries, and how partnerships build strong ecosystems.Read more, including a full transcript, here: a16z.com/how-to-build-ai-ecosystem-lisa-su-ceo-of-amdTime stamps:[00:01:37] Lisa's career in compute[00:04:48] Compute in the genAI era[00:09:39] High performance or multimodal?[00:10:47] Making the genAI ecosystem open[00:14:16] The chip supply chain[00:17:53] Resiliency and the CHIPS Act[00:20:54] How AMD balances long development cycles with short term innovation[00:24:48] Learnings from the hyperscaler market[00:26:54] What being fabless means for AMD[00:31:24] Lisa's advice for startup foundersIn our conversation series AI Revolution, we ask industry leaders how they’re harnessing the power of generative AI and steering their companies through the next platform shift. Find more content from our AI Revolution series on www.a16z.com/AIRevolution.Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
Can Open Source Collaboration Train AI? a16z 2024-10-11 | How can the open-source community collectively build and train AI? Listen to the full conversation with Nous Research's Bowen Peng and Jeffrey Quesnelle along with a16z's Anjney Midha: youtu.be/goMey2Ir-m0?si=sVAWuuhx9lnAc8JV
Unlocking New AI Training Possibilities: How Emerging Architectures Could Transform GPU Use a16z 2024-10-07 | Bowen Peng shares AI possibilities as people become aware of different methods for training LLMs.Watch the entire interview with Jeffrey Quesnelle, Bowen Peng and a16z host, Anjney Midha here: youtu.be/goMey2Ir-m0?si=E5zQ-KgMgVrxFed4
AI at the Intersection of Bio | Vijay Pande, Surya Ganguli & Bowen Liu a16z 2024-10-03 | In this episode, Vijay Pande is joined by AI experts Surya Ganguli, venture partner, and Bowen Liu, investment partner, to explore the transformational role of AI in drug discovery and biology. Together, they delve into how machine learning and self-supervised models are reshaping the foundational tasks of drug design, from protein folding to molecular synthesis. The conversation highlights cutting-edge breakthroughs like generative AI for drug discovery and the growing potential of foundation models to accelerate innovation. For biotech entrepreneurs, this episode offers an essential overview of how AI is untangling the complexity of biology, paving the way for faster, cheaper, and more effective drug development. Tune in to gain timely insights on the future of AI in healthcare and actionable takeaways that can sharpen your competitive edge in the rapidly evolving landscape of life sciences innovation.Resources: Find Vijay on X: https://x.com/vijaypande Learn more about a16z Bio+Health: a16z.com/bio-health Learn more about Raising Health: a16z.com/podcasts/raising-health Stay Updated: Find a16z Bio+Health on LinkedIn: linkedin.com/showcase/a16z-bio-health Find a16z Bio+Health on X: https://x.com/a16zBioHealth Subscribe on your favorite podcast app: a16z.com/podcasts/raising-healthDisclosure: Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
The Quest for Community-Trained Open Source AI Models a16z 2024-10-01 | Bowen Peng and Jeffrey Quesnelle of Nous Research join a16z General Partner Anjney Midha to discuss their mission to keep open source AI research alive and activate the community of independent builders. The focus is on a recent project called DisTrO, which demonstrates it's possible to train AI models across the public internet much faster than previously thought possible. However, Nous is behind a number of other successful open source AI projects, including the popular Hermes family of "neutral" and guardrail-free language models.
Why Human Data is Key to AI: Alexandr Wang from Scale AI a16z 2024-09-24 | In this conversation with a16z general partner David George, Scale AI founder and CEO Alexandr Wang discusses the three pillars of AI—models, compute, and data—and how creating abundant data is core to the evolution of gen AI. With Scale’s work across enterprise, automotive, and the public sector, Alex is also building the critical infrastructure that will allow any organization to use their proprietary data to build bespoke gen AI applications. In addition to talking about frontier data, Alex also shares his learnings from the growth of Scale, his approach to leadership, and what he thinks growth-stage founder/CEOs tend to get wrong about hiring. Read more, including a full transcript, here: a16z.com/frontier-data-foundries-alex-wang-scale-aiTimestamps:[00:00:58] How frontier data will change gen AI[00:08:47] Are big tech companies over-investing in AI?[00:14:39] Where the best AI businesses will thrive[00:17:05] How enterprise businesses are approaching AI adoption[00:19:50] What does the next phase of gen AI products look like?[00:23:23] Alex's approach to scaling Scale[00:25:36] The founder fallacy[00:30:12] MEI and how Alex views talent acquisitionIn our conversation series AI Revolution, we ask industry leaders how they’re harnessing the power of generative AI and steering their companies through the next platform shift. Find more content from our AI Revolution series on www.a16z.com/AIRevolution.Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
“The Future of AI is Here” — Fei-Fei Li Unveils the Next Frontier of AI a16z 2024-09-20 | Fei-Fei Li and Justin Johnson are pioneers in AI. While the world has only recently witnessed a surge in consumer AI, our guests have long been laying the groundwork for innovations that are transforming industries today.In this episode, a16z General Partner Martin Casado joins Fei-Fei and Justin to explore the journey from early AI winters to the rise of deep learning and the rapid expansion of multimodal AI. From foundational advancements like ImageNet to the cutting-edge realm of spatial intelligence, Fei-Fei and Justin share the breakthroughs that have shaped the AI landscape and reveal what's next for innovation at World Labs.If you're curious about how AI is evolving beyond language models and into a new realm of 3D, generative worlds, this episode is a must-listen.Timestamps: 00:00 - Spatial Intelligence: A New Frontier01:38 - Scaling AI: The Impact of ImageNet on Computer Vision06:56 - The Role of Compute09:16 - Data as the Key Driver17:01 - Defining AI’s Ultimate Goal18:58 - What is Spatial Intelligence? Unlocking 3D Understanding in AI26:35 - Comparing Models: Spatial Intelligence vs. Language-Based AI29:41 - 1D vs. 3D32:39 - Building Immersive Worlds with Spatial Intelligence 35:11 - From Static Scenes to Dynamic Worlds37:42 - The Future of VR and AR40:42 - Creating Deep Tech Platforms44:26 - Building a World-Class Team45:54 - Measuring Success: Milestones in Spatial IntelligenceResources: Learn more about World Labs: worldlabs.aiFind Fei-Fei on Twitter: https://x.com/drfeifeiFind Justin on Twitter: https://x.com/jcjohnssFind Martin on Twitter: https://x.com/martin_casadoStay Updated: Let us know what you think: ratethispodcast.com/a16z Find a16z on Twitter: twitter.com/a16z Find a16z on LinkedIn: linkedin.com/company/a16z Subscribe on your favorite podcast app: a16z.simplecast.com Follow our host: twitter.com/stephsmithio Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
Lumas Dream Machine and Reasoning in Video Models a16z 2024-09-09 | a16z General Partner Anjney Midha speaks with Luma Chief Scientist Jiaming Song about the company's recently released Dream Machine model. Among the amazing features of Dream Machine are how it learned to accurate generate 3D structures and elements from 2D videos, and how it is able to reason about things such as shot consistency and fictional worlds without explicit priors.
Implementation, Data, Impact of Healthcare AI with Julie and Vijay a16z 2024-09-05 | In this episode, Julie Yoo and Vijay Pande dive into the potential and challenges of implementing AI in healthcare. They revisit the grand challenges discussed in Part 1 of this conversation, Grand Challenges in Healthcare AI, and address new questions that have emerged, focusing on three main areas: the cost of healthcare and AI implementation, the data landscape for AI training, and patient experience.Topics covered: 00:00 - Intro00:03 - Overview of three clusters of Part 1 questions: cost, data, and patient experience00:30 - Vijay Pande discusses AI's potential to lower healthcare costs03:00 - Julie Yoo examines the impact of AI on cost structure and labor06:39 - Challenges in reducing healthcare costs in America08:15 - The role of AI in shifting from sick care to preventative care12:00 - Financial incentives and barriers to AI adoption among clinicians15:39 - Emotional and practical aspects driving AI adoption in healthcare19:42 - The importance of data sharing and the role of AI in healthcare innovation22:36 - The data advantage (or lack thereof) of legacy healthcare companies24:00 - Balancing AI-driven recommendations with clinician expertise27:00 - The role of AI in enhancing patient experience through choice and automation30:00 - Long-term vision for AI in personalized and preventative healthcareResources: Find Julie Yoo on Twitter: https://x.com/julieyooFind Vijay Pande on Twitter: https://x.com/vijaypandeLearn more about a16z Bio+Health: a16z.com/bio-healthStay Updated:Find a16z Bio+Health on LinkedIn: linkedin.com/showcase/a16z-bio-healthFind a16z Bio+Health on X: https://x.com/a16zBioHealthSubscribe on your favorite podcast app: a16z.com/podcasts/raising-healthPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
Ideogram: Unlocking Precision Image Generation a16z 2024-08-15 | Imagine a world where anyone, regardless of their artistic skill, can create stunning visual stories. In this episode, Mohammad Norouzi, cofounder and CEO of Ideogram, shares his insights on designing a platform to democratize creativity and enhance visual storytelling.Mohammad discusses Ideogram’s unique text rendering capabilities, how user feedback has helped set new standards in visual communication, and the key technical challenges they've faced. He explains how they maintain prompt adherence, achieve aesthetically-pleasing text integration, and serve a diverse user base—from professional designers to casual creators.To explore more AI applications for video, audio, photography, and animation, visit the AI Artist Retreat webpage: http://a16z.com/aiartTimestamps:00:00 - The Possibilities of AI00:21 - Ideogram’s Mission: Rekindling the Inner Creative Child01:06 - The Genesis: Why Image Generation Specifically?01:37 - Communicating With Images: Advanced Text Rendering 02:19 - Version 0.102:53 - User Input and Interactions04:20 - Prompt Adherence: What Sets Ideogram Apart05:00 - Pushing the Limits05:44 - Addressing Issues Through User FeedbackResources:Find Mohammad on X: https://x.com/mo_norouziLearn more about Ideogram: ideogram.aiStay Updated: Let us know what you think: ratethispodcast.com/a16z Find a16z on Twitter: twitter.com/a16z Find a16z on LinkedIn: linkedin.com/company/a16z Subscribe on your favorite podcast app: a16z.simplecast.com Follow our host: twitter.com/stephsmithio Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
Why will healthcare be the industry that benefits the most from AI? a16z 2024-08-15 | Julie Yoo, a16z general partner, discusses the significant impact AI can have on the healthcare industry, focusing on the unique opportunities and challenges it presents.Julie elaborates on how the healthcare sector, despite being a technological laggard, can benefit from AI due to its lack of legacy systems, contrasting it with other industries that face high costs in transitioning to AI tools.Topics covered:00:00 - Introduction to AI in healthcare00:04 - The leapfrog opportunity for AI in healthcare00:22 - Manual labor and outdated technology in healthcare00:46 - AI adoption without legacy system constraints01:12 - Workforce shortage and clinical judgment scalability01:40 - Enabling all healthcare professionals to excel02:10 - Evaluating and building trust in AI products for clinical use02:44 - Regulatory framework and FDA's role in approving AI products03:12 - Barriers to entry and market opportunities for AI in healthcare03:40 - The scale of the healthcare AI opportunity04:10 - Conclusion and future of AI in healthcareResources:Read the related article: a16z.com/why-will-healthcare-be-the-industry-that-benefits-the-most-from-aiFind Julie on LinkedIn: linkedin.com/in/juliekyooStay Updated:Find a16z Bio+Health on LinkedIn: linkedin.com/showcase/a16z-bio-healthFind a16z Bio+Health on X: https://x.com/a16zBioHealth Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures
a16z Podcast Live Panel Recording at NYTW a16z 2024-08-14 | Deliver an experience so compelling that once tried, there’s no going back.
a16z Talent x Opportunity Initiative a16z 2024-08-13 | The a16z Talent x Opportunity initiative is building a new system of funding, training, and mentorship for under networked founders building cultural breakthroughs. Take a look at the program in action!
Udio: From Text to Tune a16z 2024-08-13 | What happens when generative AI meets the universal language of music?Conor Durkan, cofounder of Udio, discusses the evolution of generative AI in music—from research curiosity to mainstream application—and how Udio is paving the way for a new era in music creation.Recorded at the AI Artist Retreat, this episode explores overcoming traditional music production's steep learning curves, showcases demos of Udio’s features, and highlights its impact on the creative community.Stay tuned for more episodes in the AI Artist Retreat series, where we spotlight founders and their platforms. For more details, visit our webpage: http://a16z.com/aiartTimestamps:00:00 - Generative AI Meets Music00:23 - The Emotional Resonance of Music01:19 - From Research Curiosity to Mainstream Application02:22 - DEMO: Creating a Song04:17 - Samples by Metro Boomin & Drake05:16 - Catering to musicians and hobbyistsResources:Find Connor Durkan on X: https://x.com/conormdurkanLearn more about Udio: udio.comStay Updated: Let us know what you think: ratethispodcast.com/a16z Find a16z on Twitter: twitter.com/a16z Find a16z on LinkedIn: linkedin.com/company/a16z Subscribe on your favorite podcast app: a16z.simplecast.com Follow our host: twitter.com/stephsmithio Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
Building upon existing breakthroughs in AI a16z 2024-08-12 | Despite all the recent breakthroughs in AI, Waymo co-CEO Dmitri Dolgov believes that the most challenging problems lie within the remaining 0.001% of the curve, and solving them requires building upon existing innovations.
Optimizing simulation for autonomous driving a16z 2024-08-08 | Waymo is changing the way we move through its simulation technology, Co-CEO Dmitri Dolgov told a16z at AI Revolution.
Viggle: When Memes Become 3D a16z 2024-08-08 | Hang Chu, co-founder of Viggle, discusses redefining video creation by providing precise control over character movements and animations. Unlike traditional tools, Viggle simplifies generating lifelike animations using image and motion prompts, making it accessible to professionals and meme creators."For it to have real entertaining value, it has to work well. We're pretty serious about being silly," says Hang. He also talks about the critical role of R&D, strategies for achieving virality, personalizing content, and being open to unexpected product applications.Catch upcoming episodes of the AI Artists Retreat series, where we feature more founders and explore their platforms and company-building journeys: http://a16z.com/aiartTimestamps:00:00 - Achieving Real Entertainment Value00:25 - Controllable Video Generation00:52 - User-Friendly Design01:20 - Going Viral: Joker Meets Lil Yachty02:26 - DEMO: Combining Motion and Character Prompts03:02 - Building a Creative Community 03:56 - Scaling with Precision: Ensuring Controllability04:54 - Personalized ExperiencesResources:Find Hang on X: https://x.com/chuhang1122Learn more about Viggle: viggle.aiStay Updated: Let us know what you think: ratethispodcast.com/a16z Find a16z on Twitter: twitter.com/a16z Find a16z on LinkedIn: linkedin.com/company/a16z Subscribe on your favorite podcast app: a16z.simplecast.com Follow our host: twitter.com/stephsmithio Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
Krea: Building the UI for AI Art a16z 2024-08-06 | "What are the interactions? What are the dials that we need to expose for people to be able to use this technology creatively?"Victor Perez and Diego Rodriguez, Krea's cofounders, share how Krea empowers artists to generate and enhance images and videos using AI without needing to master complex technical skills.Victor and Diego discuss their journey from deep research to creating user-friendly interfaces that make AI a seamless creative medium. They highlight the importance of turning complex technology into accessible products, building community-driven development, and staying agile in a fast-moving tech landscape.Stay tuned for more episodes in the AI Artist Retreat series, where we spotlight founders and their platforms. For more details, visit our webpage: www.a16z.com/aiart Timestamps:00:00 - Introduction to Krea00:42 - Identifying Market Needs01:18 - DEMO: Real-Time Image Generation and User Controls02:17 - Fine-Tuning AI Creativity for Artists02:38 - Empowering Artists with AI03:13 - Layering: Refining Your Creative Output03:56 - Achieving Viral Success05:13 - Krea's Unique Value PropositionResources:Find Victor on: linkedin.com/in/iamvictorperezFind Diego on X: https://x.com/asciidiegoLearn more about Krea: krea.ai/homeStay Updated: Let us know what you think: ratethispodcast.com/a16z Find a16z on Twitter: twitter.com/a16z Find a16z on LinkedIn: linkedin.com/company/a16z Subscribe on your favorite podcast app: a16z.simplecast.com Follow our host: twitter.com/stephsmithio Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
Waymo And A Safer Future, From AI Revolution #autonomousvehicles a16z 2024-08-05 | Does the perfect driver exist?
How Waymo Is Using GenAI to Build a Better Driver a16z 2024-08-05 | Waymo co-CEO Dmitri Dolgov discusses how genAI is propelling Waymo’s autonomous vehicles to the next level, especially with an additional simulation layer on top of Waymo’s existing AI/ML stack. Waymo co-CEO Dmitri Dolgov joined a16z general partner David George to discuss how Waymo is using genAI to help them build safer, sustainable, and more accessible transportation. In the conversation, Dmitri talks about the potential of embodied AI, the value of simulations and building training data, and his approach to leading a company focused on solving the challenges of building AI that can navigate the real world.[00:01:22] The early days of autonomous vehicles[00:05:27] Layering genAI into traditional AI/ML[00:09:42] The value of simulation[00:15:56] The hard part about integrating AI in autonomous systems[00:22:45] AI in the real world[00:28:47] Where does Waymo go from here?[00:37:21] Dmitri's learnings from hard problemsThis conversation is part of our AI Revolution series, which features some of the most impactful builders in the field of AI discussing and debating where we are, where we’re going, and the big open questions in AI. Find more content from our AI Revolution series on www.a16z.com/AIRevolution.
On Fast Growth with Capital Groups Mark Casey a16z 2024-08-02 | Why it's crucial to ask: Is the moat wide enough to ensure profitability?
AI in Pharmaceutical R&D with Kim Branson a16z 2024-08-01 | In this episode, Vijay Pande talks with Kim Branson, the SVP and Global Head of AI and Machine Learning for GSK, about his journey from a childhood fascination with computers to leading AI efforts in a major pharmaceutical company.They discuss Branson's career path, the intersection of computation and biology, and the challenges and opportunities in integrating AI into drug discovery and development.Topics covered:00:00 - Introduction to Kim Branson and his background00:15 - Early interest in computers and transition to molecular biology01:20 - Experience with computational methods in drug design02:10 - Differences between working in startups and large pharmaceutical companies04:05 - Decision to join GSK and the company’s commitment to AI06:10 - Implementing AI in drug discovery processes08:35 - Use of genetic databases and machine learning in target identification10:55 - Application of AI in clinical trials and pathology12:40 - Importance of data in AI-driven drug discovery16:55 - Challenges of integrating AI into existing pharmaceutical frameworks18:15 - Advice for startups in the AI and drug discovery space24:20 - Future of AI in personalized medicine and computational biologyResources:Find Vijay on Twitter: https://x.com/vijaypande Learn more about a16z Bio+Health: a16z.com/bio-healthLearn more about Raising Health: a16z.com/podcasts/raising-healthStay Updated:Find a16z Bio+Health on LinkedIn: linkedin.com/showcase/a16z-bio-healthFind a16z Bio+Health on X: https://x.com/a16zBioHealth Subscribe on your favorite podcast app: raisinghealth.simplecast.comPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
Civitai: Open Sourcing AI Art a16z 2024-08-01 | “The home of the open source artist”. Justin Maier and Maxfield Hulker, cofounders of Civitai, share how they transformed a niche idea into a platform with millions of users, fostering a community that shares tools and know-how for creating unique AI art. Listen to the podcast episode where they cover topics like balancing monetization with open source principles, incentivizing and rewarding the community, and more: a16z.simplecast.com/episodes/when-ai-meets-artStay tuned for more episodes from the AI Artist Retreat series, featuring founders and their cutting-edge AI platforms. Learn more about the AI Artist Retreat on our webpage: a16z.com/aiartTimecodes:00:00 - The Motivation Behind Civitai00:40 - The Need for a Dedicated Ecosystem Platform01:07 - Building the Home of the Open Source Artist 01:40 - DEMO: Generation Data, Community Models and LoRas 02:30 - Fostering Community02:54 - The Policies and Moderation of AI Art03:36 - Audits and Semi-Permeable Membrane Technology (SPM)05:00 - DEMO: Training Data 05:42 - Engaging and Rewarding the Community06:30 - Innovations and Next StepsResources:Find Justin on Twitter: https://x.com/JustMaierFind Maxfield on: linkedin.com/in/maxfield-hulker-5222aa230Learn more about Civitai: civitai.comStay Updated: Let us know what you think: ratethispodcast.com/a16z Find a16z on Twitter: twitter.com/a16z Find a16z on LinkedIn: linkedin.com/company/a16z Subscribe on your favorite podcast app: a16z.simplecast.com Follow our host: twitter.com/stephsmithio Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
ElevenLabs: Bringing Voice to Life a16z 2024-07-30 | AI-driven voice technology is revolutionizing how we interact with digital content. Recorded at the a16z AI Artist Retreat, Head of Design Ammaar Reshi walks through the advancements in AI-driven voice interactions and sound design, showing how technology enables us to bring our creative visions to life by imagining and creating the perfect soundscapes for any project.Keep an eye out for more in our series highlighting the founders building groundbreaking foundation models and AI applications for video, audio, photography, animation, and more. Learn more about the AI Artist Retreat on our webpage: a16z.com/aiartResources:Find Ammaar on Twitter: https://x.com/ammaarLearn more about ElevenLabs: elevenlabs.ioListen to the full episode 'When AI Meets Art': a16z.simplecast.com/episodes/when-ai-meets-artTimestamps:00:00 - The dream of voice interactions with AI products00:48 - The potential of general AI audio models01:37 - Creating the perfect sounds for projects03:09 - Balancing familiarity with cutting-edge tools03:37 - Multilingual voices and content creation for new audiences04:02 - Safety and moderation in audio contentStay Updated: Let us know what you think: ratethispodcast.com/a16z Find a16z on Twitter: twitter.com/a16z Find a16z on LinkedIn: linkedin.com/company/a16z Subscribe on your favorite podcast app: a16z.simplecast.com Follow our host: twitter.com/stephsmithio Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
Investor Insights: Attracting the Right Audience for Long-Term Success a16z 2024-07-23 | Customer focus is key to enduring success.
Public Market and Macro Perspectives a16z 2024-07-23 | In this episode, which took place at a16z's Connect Fintech event, a16z General Partner David George interviews Capital Group's Mark Casey on his investment philosophy, what sends him into what he calls "barnacle mode," his preference for customer-focused North Star metrics, and more. “In the Vault” is a new audio podcast series by the a16z Fintech team, where we sit down with the most influential figures in financial services to explore key trends impacting the industry and the pressing innovations that will shape our future. 0:00 - Intro1:42 - Approach to investing5:58 - What Casey told Jeff Bezos, and what he learned8:20 - How CEOs communicate with public market investors; unconventional North Star metrics12:57 - Why Casey loves dividends15:48 - Macro trends and investing theses20:44 - Ecommerce predictions21:37 - Opportunities and choke points in AI23:15 - What makes a great public company?Full transcript: a16z.com/podcast/in-the-vault-public-market-and-macro-perspectives Resources:Find "In The Vault" on a16z.com: a16z.com/podcasts/in-the-vault Find more about a16z's vision for the future of fintech: a16z.com/banking-on-AIFind David George on X: https://x.com/DavidGeorge83Find Mark Casey on LinkedIn: linkedin.com/in/markcasey92Find a16z on X: https://x.com/a16zFind a16z on LinkedIn: linkedin.com/company/a16zSubscribe to the a16z Fintech newsletter:info.a16z.com/newsletters-fintech.html
Trump Vs. Biden: Tech Policy a16z 2024-07-16 | Welcome to "The Ben & Marc Show," featuring a16z co-founders Marc Andreessen and Ben Horowitz. In this new episode, Marc and Ben discuss their latest article, “The Little Tech Agenda,” and why the future of American innovation is at a critical juncture.In a one-on-one conversation, Ben and Marc compare the policies of Donald Trump and Joe Biden regarding Little Tech, explore the potential futures for blockchain, crypto, and AI, and examine how tax policies could shape the future of startups and venture capital.They also address the recent assassination attempt on President Trump and reveal which candidate they’ll be supporting in the upcoming election. Enjoy!*Read Marc and Ben's “The Little Tech Agenda”: a16z.com/the-little-tech-agenda Topics Covered:00:00:49 Intro to Little Tech Agenda and presidential election impact00:03:33 Involvement in presidential politics00:11:24 Importance of Little Tech00:24:01 Blockchain, crypto and stakeholder capitalism00:28:52 Challenges faced in the crypto industry 00:35:59 Trump's stance on emerging industries00:37:20 Biden admin's assault on a nascent industry00:38:51 Significance of AI in America00:42:42 Discussion on Executive Order limiting math operations in AI00:53:33 Trump's position on AI00:55:17 AI regulation00:58:23 Biotech and the Biden administration01:00:09 AI and military technology01:03:52 Biden admin's destructive tax policy for startups01:17:18 President Trump and Little Tech01:18:42 Assassination attempt on President Trump01:25:27 The strength of American presidents01:26:38 Closing remarks01:30:44 Sign off#tech #technology #startup #vc #LittleTechAgenda #PresidentialRace2024 #business #blockchain #crypto #artificialintelligence #ai #fintech #innovation #techpolicy #donaldtrump #joebiden #politics #policy #washington Book mentioned on this episode:- “Men, Machines, and Modern Times” by Elting Morison amzn.to/4f4eWrtListen to Us! - Apple: bit.ly/3SdsfNt - Spotify: https://spoti.fi/3SclPOr Resources: Marc on X: twitter.com/pmarca Marc’s Substack: pmarca.substack.com Ben on X: twitter.com/bhorowitz Stay Updated: Find us on X: twitter.com/a16z Find us on LinkedIn: linkedin.com/company/a16z The views expressed here are those of the individual personnel quoted and are not the views of a16z or its affiliates. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors and may not under any circumstances be relied upon when making a decision to invest in any a16z funds. PLEASE SEE MORE HERE: a16z.com/disclosures
Marc Andreessen on Building Netscape & the Birth of the Browser a16z 2024-06-28 | "We decided to design for the future." – Marc Andreessen | Welcome back to "The Ben & Marc Show," featuring a16z co-founders Marc Andreessen and Ben Horowitz. In this special episode, Marc and Ben dive deep into the REAL story behind the creation of Netscape—a web browser co-created by Marc that revolutionized the internet and changed the world. As Ben notes at the top, until today, this story has never been fully told either in its entirety or accurately.In this one-on-one conversation, Marc and Ben discuss Marc's early life and how it shaped his journey into technology, the pivotal moments at the University of Illinois that led to the development of Mosaic (a renegade browser that Marc developed as an undergrad), and the fierce competition and legal battles that ensued as Netscape rose to prominence.Ben and Marc also reflect on the broader implications of Netscape's success, the importance of an open internet, and the lessons learned that still resonate in today's tech landscape (especially with AI). That and much more. Enjoy!Topics covered:00:00:00 Teaser00:00:30 Intro00:02:09 Disclaimers00:04:08 Marc's early life and education00:08:18 Early exposure to personal computers and BBSs00:13:44 University of Illinois 00:16:21 Credit to Al Gore00:18:09 "The internet would never be a business."00:22:02 Interactive television / Reed Hastings' vision for Netflix00:25:16 Early internet usage and community00:29:13 Paul Baran 00:33:46 Consumer online services in the early 90s 00:39:15 NCSA 00:49:27 Development of Mosaic / Design philosophy00:58:20 Opposition in the internet community 01:01:04 Going rogue and building Mosaic01:05:06 Marc becomes customer support for the entire internet01:08:26 Media and press reaction to Mosaic01:14:46 The ping pong effect / Key moments for the Internet01:19:27 First E-commerce site 01:22:06 Graduation from UIUC01:25:39 Jim Clark / Decision to build an internet browser01:34:30 Marc on expert predictions01:38:43 Building Mosaic / Conflict w/ Spyglass01:44:05 Lawsuit against the University of Illinois 01:49:34 Parallels to modern AI discussions01:51:40 The end of Spyglass ("A happy ending")01:54:40 Sign off#internet #podcast #history #tech #technology #entrepreneur #entrepreneurship #vc #founder #ai #artificialintelligence #business #vr #starwars #netflix #computer #netscape #marcandreessen #benhorowitz Book mentioned on this episode:- “Expert Political Judgment” by Philip E. Tetlock bit.ly/45KzP6M TV Series mentioned on this episode:- “The Mandalorian” (Disney+) bit.ly/3W0Zyoq Listen to Us! - Apple: bit.ly/3SdsfNt - Spotify: https://spoti.fi/3SclPOr Resources: Marc on X: twitter.com/pmarca Marc’s Substack: pmarca.substack.com Ben on X: twitter.com/bhorowitz Stay Updated: Find us on X: twitter.com/a16z Find us on LinkedIn: linkedin.com/company/a16z The views expressed here are those of the individual personnel quoted and are not the views of a16z or its affiliates. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors and may not under any circumstances be relied upon when making a decision to invest in any a16z funds. PLEASE SEE MORE HERE: a16z.com/disclosures
Grand Challenges in Healthcare AI with Vijay Pande and Julie Yoo a16z 2024-06-28 | In this episode, Julie and Vijay discuss the transformative potential of AI in the healthcare industry, an area traditionally resistant to technological adoption. They dive into the grand challenges facing healthcare AI builders and explore the immediate and long-term impacts AI could have on healthcare.Topics covered:00:00 - Introduction to the potential of AI in healthcare00:16 - Immediate impacts of AI: Technology and human adoption01:36 - Addressing labor shortages and technology burdens in healthcare02:50 - The importance of behavior change and scaling proven solutions04:14 - Use cases for AI in healthcare: Administrative and clinical applications06:08 - Automating revenue cycle management and payment flows08:08 - Enhancing healthcare scheduling and reducing waste10:16 - The role of AI in optimizing healthcare systems11:36 - Integrating AI into electronic health records (EHR) for better patient stories13:40 - The potential of AI co-pilots for doctors and nurses16:18 - Regulatory considerations for AI in healthcare18:14 - The concept of an AI doctor and the future of AI in clinical decision-making20:40 - Always-on clinical trial infrastructure powered by AIResources:Find Julie on X: https://x.com/julesyoo Find Vijay on X: https://x.com/vijaypande Learn more about a16z Bio+Health: a16z.com/bio-healthLearn more about Raising Health: a16z.com/podcasts/raising-healthStay Updated:Find a16z Bio+Health on LinkedIn: linkedin.com/showcase/a16z-bio-health Find a16z Bio+Health on X: https://x.com/a16zBioHealth Subscribe on your favorite podcast app: raisinghealth.simplecast.comPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
How Discord Became a Developer Platform a16z 2024-06-23 | In 2009 Discord cofounder and CEO, Jason Citron, started building tools and infrastructure for games. Fast forward to today and the platform has over 200 million monthly active users. In this episode, Jason, alongside a16z General Partner Anjney Midha—who merged his company Ubiquity6 with Discord in 2021—shares insights on the nuances of community-driven product development, the shift from gamer to developer, and Discord’s longstanding commitment to platform extensibility. Now, with Discord's recent release of embeddable apps, what can we expect now that it's easier than ever for developers to build? Timecodes:00:00 - Introduction02:30 - From Player to Developer: Building Game Infrastructure and Early Projects07:45 - The Evolution of Discord: The Vision for Discord in 2012 and Its Rapid Growth11:33 - How the Discord Community Shapes the Product15:40 - The Importance of an Open API and Developer Tools16:59 - The Rise of Generative AI on Discord18:48 - Discord’s Embeddable Apps21:01 - The Future of Apps on Discord: New Genres in Gaming and Apps34:16 - Launch of the Embedded App SDK36:39 - Building Sustainable Businesses on Discord44:01 - Future Outlook and Developer AspirationsResources: Find Jason on Twitter: twitter.com/jasoncitronFind Anjney on Twitter: twitter.com/AnjneyMidhaStay Updated: Find a16z on Twitter: twitter.com/a16z Find a16z on LinkedIn: linkedin.com/company/a16z Subscribe on your favorite podcast app: a16z.simplecast.com Follow our host: twitter.com/stephsmithio Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
Embedded Payments a16z 2024-06-20 | The future of payments is not just in fintech….But in embedded finance.Full episode: youtube.com/watch?v=8CVBEk0PnVI
New Applications in Fintech a16z 2024-06-20 | In this conversation from 16z's Connect Fintech event, a16z General Partner Angela Strange, Plaid CEO and cofounder Zach Perret, and Marqeta CEO Simon Khalaf discuss how AI will shape the future of banking, the battle between payment rails in the U.S., and how there's still opportunity to transform the basic credit card into a fully digital product. “In the Vault” is a new audio podcast series by the a16z Fintech team, where we sit down with the most influential figures in financial services to explore key trends impacting the industry and the pressing innovations that will shape our future. 0:00 - Intro1:56 - GenAI's potential impact on credit modeling and fraud4:46 - Implications of payment products becoming digital products 7:09 - Why brands will embed finance8:33 - The card vs. pay-by-bank debate11:01 - New infrastructure to combat fraud12:24 - Reassessing traditional "top-of-wallet" tactics, historic business models17:27 - Potential implications of the Visa/Mastercard antitrust suit20:04 - Regulation around open banking and sponsor banks24:12 - OutroFull transcript: a16z.com/podcast/in-the-vault-new-applications-in-fintech-with-plaid-and-marqetaResources:Find "In The Vault" on a16z.com: a16z.com/podcasts/in-the-vault Find more about a16z's vision for the future of fintech: a16z.com/banking-on-AIFind Angela Strange on X: https://x.com/astrangeFind Zach Perret on X: https://x.com/zachperretFind Simon Khalaf on X: https://x.com/SimonkhalafFind a16z on X: https://x.com/a16zFind a16z on LinkedIn: linkedin.com/company/a16zSubscribe to the a16z Fintech newsletter:info.a16z.com/newsletters-fintech.html
Marc Andreessen & Andrew Chen Talk Creative Computers a16z 2024-06-19 | The gaming industry is a pioneer of cutting-edge technologies, ushering in innovations like GPUs, virtual and augmented reality, physics engines, and immersive multiplayer experiences.Recorded as part of a16z's games fund accelerator, SPEEDRUN, the a16z cofounder Marc Andreessen and Andrew Chen, General Partner at a16z Games, discuss why a16z was compelled to establish a dedicated games fund. They explore the origins of tech pessimism, effective engagement with government in tech, its significance for the gaming community, the ongoing AI revolution, and even what Marc himself would build today if he didn’t have his hands full.Timecodes: 00:00 - Introduction00:42 - The Bonding Power of Gaming02:32 - How Gaming Drives Technological Innovation05:32 - Technological Transitions: Moral Panics and the Promise of Progress11:48 - Government, Innovation, and the Role of Regulation21:37 - Envisioning the Future of Immersive Experiences25:32 - AI as a Partner33:00 - Big Models vs. Open Innovation36:28 - Why a16z launched a games fund43:29 - Shaping the Future of Gaming and TechnologyResources: Find Marc on Twitter: twitter.com/pmarcaFind Andrew on Twitter: twitter.com/andrewchenLearn more about SPEEDRUN: a16z.com/games/speedrunStay Updated: Find a16z on Twitter: twitter.com/a16z Find a16z on LinkedIn: linkedin.com/company/a16z Subscribe on your favorite podcast app: a16z.simplecast.com Follow our host: twitter.com/stephsmithio Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
SPEEDRUN: Building AI Souls with Personality a16z 2024-06-14 | SPEEDRUN is all about rapid innovation: go fast, learn, and build better. In Speedrun 002, dozens of game founders pushed the boundaries of AI, AR, VR, Web3, and more.One of those founders was Kevin Fischer, founder and CEO of Open Souls, who’s on a mission to create AI souls that deeply resonate with humanity. Kevin’s journey started in childhood and now, with the Soul Engine, his team empowers developers to easily create lifelike AI, transforming how we connect and interact with computers.Resources:Learn more about SPEEDRUN: a16z.com/games/speedrunLearn more about Open Souls: https://www.opensouls.studioFind Kevin on Twitter: twitter.com/KevinAFischerFind Andrew on Twitter: twitter.com/andrewchenFind Josh on Twitter: twitter.com/JoshLuStay Updated: Find a16z on Twitter: twitter.com/a16z Find a16z on LinkedIn: linkedin.com/company/a16z Subscribe on your favorite podcast app: a16z.simplecast.com Follow our host: twitter.com/stephsmithio Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.Digital Souls: The Future of AI in Gaming
The Future of Prosumer: The Rise of “AI Native” Workflows a16z 2024-06-11 | Generative AI presents an incredible opportunity for founders to completely reinvent workflows, paving the way for a new wave of companies that are not just AI-augmented but fully AI-native. These companies will leverage the latest technology to build products around the unique generation, editing, and composition capabilities made possible by AI.a16z Partner Olivia Moore highlights the features of today's most successful Gen AI-native workflows and offers insights into how these products are expected to evolve in the future.Timecodes:00:00 - The Shift from AI-Augmented to AI-Native Products04:28 - Mastering Iteration and Refinement in AI Products08:23 - AI Remixing: Transforming Creativity Across Media10:24 - The Evolution of AI Integration: From Single Features to Comprehensive PlatformsResources:Link to Olivia’s article: a16z.com/the-future-of-prosumer-the-rise-of-ai-native-workflowsFind Olivia on Twitter: https://x.com/omooretweets Stay Updated: Find a16z on Twitter: twitter.com/a16z Find a16z on LinkedIn: linkedin.com/company/a16z Subscribe on your favorite podcast app: a16z.simplecast.com Follow our host: twitter.com/stephsmithio Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
The Top 100 GenAI Consumer Apps a16z 2024-06-04 | Consumer AI is moving fast. Who’s leading the charge?Olivia Moore, partner at a16z, took a renewed look at our Top 100 Gen AI Consumer Apps list with Steph Smith on the a16z podcast and, for the first time, broke the list down by web and mobile categories.Timecodes:00:00 - The top 100 genAI list01:30 - Mobile vs. web04:53 - Newcomers and companies that moved up the list07:38 - User visits and interactions 09:03 - AI is a global pursuit 10:18 - New categories: music, productivity tools12:11 - Upcoming trends Resources:Link to the Gen AI 100: a16z.com/100-gen-ai-appsFind Olivia on Twitter: https://x.com/omooretweetsStay Updated: Find a16z on Twitter: twitter.com/a16z Find a16z on LinkedIn: linkedin.com/company/a16z Subscribe on your favorite podcast app: a16z.simplecast.com Follow our host: twitter.com/stephsmithio Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
7 Ways to Boost Retention (Both Pre- and Post-AI) a16z 2024-05-31 | For consumer products, the rubber hits the road at user retention. In this episode, a16z Partner Bryan Kim covers the seven most effective ways for AI-native consumer companies to improve user retention. From essential strategies to proven methods, Bryan reveals how leading AI-native products are already benefiting from these approaches. Featuring real-world examples from companies like Snapchat, Google, Perplexity, and BeReal, this is a must-watch for founders, product managers, and anyone interested in the latest AI and consumer application trends. Packed with valuable insights, this video will help you enhance your product's retention and success.Timecodes:03:26 - Obsess Over Delivering the Core Product Value. Fast.06:11 - Feature-Gated Onboarding10:07 - Designing Reciprocity12:10 - Building Smart Notifications17:12 - Give Them Summaries19:54 - Keeping Streaks Alive22:14 - Status for the Power UsersResources:Link to Bryan’s article: a16z.com/7-ways-ai-native-companies-can-improve-retentionFind Bryan on Twitter: twitter.com/kirbyman01Stay Updated: Find a16z on Twitter: twitter.com/a16z Find a16z on LinkedIn: linkedin.com/company/a16z Subscribe on your favorite podcast app: a16z.simplecast.com Follow our host: twitter.com/stephsmithio Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
What Happens If Theres ZERO AI Regulation? a16z 2024-05-28 | What happens if there is zero regulation of AI? In this clip from a recent episode of "The Ben & Marc Show", the guys weigh in on the "good, bad and ugly" of this scenario.* Watch the FULL episode: youtu.be/dX7d6bRJI9k #clips #ai #politics #business #tech #technology #artificialintelligence #entrepreneur #entrepreneurship #government #startups Resources: Marc on X: twitter.com/pmarca Marc’s Substack: pmarca.substack.com Ben on X: twitter.com/bhorowitz Stay Updated: Find us on X: twitter.com/a16z Find us on LinkedIn: linkedin.com/company/a16z The views expressed here are those of the individual personnel quoted and are not the views of a16z or its affiliates. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors and may not under any circumstances be relied upon when making a decision to invest in any a16z funds. PLEASE SEE MORE HERE: a16z.com/disclosures
Can AI Advance Science? DeepMinds VP of Science Weighs In a16z 2024-05-21 | DeepMind's VP of Research for Science, Pushmeet Kohli, and a16z General Partner Vijay Pande discuss AI's transformative potential in scientific exploration. Can AI lead to fundamentally new discoveries in science? Topics Covered: 00:00 - The Incomprehensibility of Modern Data00:52 - AI Discovering New Mathematical Insights02:30 - Cultural Shifts in the Perception of AIResources: Listen to the full episode: a16z.simplecast.com/episodes/can-ai-advance-science-deepminds-vp-of-science-weighs-inFind Pushmeet on Twitter: twitter.com/pushmeetFind Vijay on Twitter: twitter.com/vijaypandeLearn more about Google DeepMind: https://deepmind.googleStay Updated: Find a16z on Twitter: twitter.com/a16z Find a16z on LinkedIn: linkedin.com/company/a16z Subscribe on your favorite podcast app: a16z.simplecast.com Follow our host: twitter.com/stephsmithio Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.
The Future of the American Dream a16z 2024-05-20 | Are we on the verge of a new American Dream?Welcome back to "The Ben & Marc Show," featuring a16z co-founders Marc Andreessen and Ben Horowitz. In this timely new episode, Marc and Ben explore the foundations of American life and identity.From the material aspects of home ownership, education, and healthcare, to the intangible aspects of community and self-actualization, Ben and Marc reveal what it truly means to be American today. They also examine the numerous challenges our nation now faces, as well as reveal how technology can soon revolutionize American life, business and culture in unprecedented ways. That and more. Enjoy!Topics covered:00:00:00 Teaser00:00:31 Intro00:02:28 Home ownership, education and healthcare00:05:43 Self-actualization00:07:57 Industrial Revolution's impact on the American Dream00:09:21 Cultural aspects00:10:02 The Promised Land 00:15:52 Anybody can become American00:20:24 Protestant ethics as a foundation to the American Dream00:27:40 Tribalism 00:31:53 Economy bifurcated into Fast vs. Slow categories00:36:33 Subsidizing demand and restricting supply leads to high prices00:39:18 The Doom Loop00:41:30 How tech can help us achieve the American Dream00:43:43 Accreditation process in higher ed00:48:25 Zero-sum mentality as a foundation for populism00:50:19 Are we on the verge of a new American Dream?00:53:10 American Dream in the AI era00:57:20 Rise of general purpose robotics 01:00:16 Automation of bureaucracy 01:02:24 Sign off#america #americandream #history #tech #technology #entrepreneur #entrepreneurship #vc #founder #podcast #robot #robotics #ai #artificialintelligence #education #housing #politicsListen to Us! - Apple: bit.ly/3SdsfNt - Spotify: https://spoti.fi/3SclPOr Books mentioned on this episode:- "America Betrayed" by David Horowitz amzn.to/3QNSGrm- "The Weirdest People in the World" by Joseph Henrich amzn.to/4bL2CKfChart:- Mark J. Perry's "Chart of the Century" bit.ly/4asusKuResources: Marc on X: twitter.com/pmarca Marc’s Substack: pmarca.substack.com Ben on X: twitter.com/bhorowitz Stay Updated: Find us on X: twitter.com/a16z Find us on LinkedIn: linkedin.com/company/a16z The views expressed here are those of the individual personnel quoted and are not the views of a16z or its affiliates. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors and may not under any circumstances be relied upon when making a decision to invest in any a16z funds. PLEASE SEE MORE HERE: a16z.com/disclosures
AI, Robotics & the Future of Manufacturing a16z 2024-05-16 | Welcome back to "The Ben & Marc Show," featuring a16z co-founders Marc Andreessen and Ben Horowitz. In this new episode – the second in a 2 part series – Marc and Ben address a new round of questions regarding the "State of AI" in relation to company building.**Watch Part 1: youtu.be/XyrBJ0gk-is In light of recent developments at Boeing, Marc and Ben commence the episode with a discussion on the real criteria boards utilize to select a CEO. Returning to the topic of AI, they explore the potential for emerging chip startups, the incorporation of AI in robotics, and what America will need to do in order to regain its position as the world's leading manufacturer. That and more. Enjoy!Topics Covered: 00:00:00 Teaser00:00:44 Intro / Nascent meme alert!00:01:51 Boeing CEOs background raises questions00:05:30 How a Board hires a CEO00:06:51 Hiring for magnitude of strength vs. lack of weakness00:10:46 Importance of incentive at the board level00:12:35 When personal incentives override goal of the organization00:14:50 Career path for CEOs 00:17:10 Most essential skill of a CEO00:20:30 Long-suffering #2 executive & external recruitment00:25:17 How boards are really selected 00:29:32 Poor laws around boards; pressure from social activists00:32:38 Energy innovation and the future of AI00:35:38 Potential for new chip startups00:37:32 Challenges of building hardware companies 00:39:18 Investing in hardware vs. software companies00:43:24 Venture process: What the smartest founders know00:49:04 Low-cost Power Data Centers for AI00:51:23 Flexibility in training runs 00:53:45 Government scrutiny00:55:03 AIs impact on service businesses00:58:24 Most overblown fear of AI01:00:33 Integration of AI in robotics01:05:41 Tesla and The Bitter Lesson of AI01:12:02 Revitalizing U.S. manufacturing with AI and robots01:19:35 Sign off#ai #startups #business #technology #entrepreneur #entrepreneurship #tech #vc #founder #podcast #boeing #robot #robotics #artificialintelligence #manufacturing #america Listen to Us!- Apple: bit.ly/3SdsfNt- Spotify: https://spoti.fi/3SclPOrArticle mentioned:- "Ones and Twos" by Ben Horowitz a16z.com/ones-and-twosBook mentioned:- "Elon Musk" by Walter Isaacson amzn.to/3wyGOmoResources:Marc on X: twitter.com/pmarca Marc’s Substack: pmarca.substack.com Ben on X: twitter.com/bhorowitz Stay Updated: Find us on X: twitter.com/a16z Find us on LinkedIn: linkedin.com/company/a16z The views expressed here are those of the individual personnel quoted and are not the views of a16z or its affiliates. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors and may not under any circumstances be relied upon when making a decision to invest in any a16z funds. PLEASE SEE MORE HERE: a16z.com/disclosures
AI Boom Vs. Internet Boom a16z 2024-05-13 | How does the current AI boom compare to the past internet boom? Marc Andreessen and Ben Horowitz explain in this clip.Watch the FULL episode of "The Ben & Marc Show" here: youtu.be/XyrBJ0gk-is#clips #ai #internet #business #tech #technology #founders #90s #artificialintelligence #entrepreneur #entrepreneurship #culture Resources:Marc on X: twitter.com/pmarca Marc’s Substack: pmarca.substack.com Ben on X: twitter.com/bhorowitz Stay Updated: Find us on X: twitter.com/a16z Find us on LinkedIn: linkedin.com/company/a16z The views expressed here are those of the individual personnel quoted and are not the views of a16z or its affiliates. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors and may not under any circumstances be relied upon when making a decision to invest in any a16z funds. PLEASE SEE MORE HERE: a16z.com/disclosures
Time to Change the World 🌎 #entrepreneur #ai #technology a16z 2024-05-11 | NEW episode out now! Ben Horowitz & Marc Andreessen unpack the current “State of AI” as it relates to building a company on the latest “Ben & Marc Show”.Watch & join the conversation! youtu.be/XyrBJ0gk-is
Build Your Startup With AI a16z 2024-05-09 | Welcome back to "The Ben & Marc Show," featuring a16z co-founders Marc Andreessen and Ben Horowitz. In this new episode – the first of two parts – Marc and Ben answer YOUR questions on the “State of AI” as it relates to company building.In this one-on-one conversation, Ben and Marc discuss how small AI startups can compete with Big Tech’s massive compute and data scale advantages, unpack the reasons why data is overrated as a sellable asset, and uncover all the ways the AI boom compares to the internet boom. That and much more. Enjoy!**Watch Part II: youtu.be/QyyWsr1NMt8Topics Covered:00:00:00 Teaser00:00:42 Intro00:01:14 How AI startups can compete with the bigger players00:05:57 Will the the "God models" get 100x better?00:09:19 Counter argument: Are the tests too simple?00:10:14 Internet data represents average human activity00:11:50 AI's ability to unlock latent super genius limits00:15:30 Neural networks exhibit generalized learning and computation functions00:17:01 Reports of self improvement loops00:19:10 Current data improvements00:22:05 Challenges for AI applications00:25:48 Business value-based pricing model00:29:38 Two diametrically opposed questions about AI's impact on tech investment00:32:48 The Jevons Paradox 00:36:46 John Maynard Keynes vs. Karl Marx00:39:29 Demand for softwares is perfectly elastic 00:41:12 AI based medical diagnosis00:42:09 Reality of data moats 00:48:06 Big companies and actionable data validation 00:52:05 Big companies using stolen data00:53:07 Genetic Information Nondiscrimination Act (GINA)00:57:53 Comparison of AI boom and internet boom01:02:23 Marc's prediction for the AI industry01:08:07 Lessons learned from internet era 01:12:12 Big companies trying to lock down AI01:13:28 Core VC assumes half of investments will fail01:19:25 Sign off#ai #startup #business #tech #technology #founders #artificialintelligence #internet #entrepreneur #entrepreneurship #culture #news Listen to Us!- Apple: bit.ly/3SdsfNt- Spotify: https://spoti.fi/3SclPOrResources:Marc on X: twitter.com/pmarca Marc’s Substack: pmarca.substack.com Ben on X: twitter.com/bhorowitz Stay Updated: Find us on X: twitter.com/a16z Find us on LinkedIn: linkedin.com/company/a16z The views expressed here are those of the individual personnel quoted and are not the views of a16z or its affiliates. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors and may not under any circumstances be relied upon when making a decision to invest in any a16z funds. PLEASE SEE MORE HERE: a16z.com/disclosures
Truth About Boeings CEO ✈️ #boeing a16z 2024-05-03 | "The Ben & Marc Show" features a16z co-founders Marc Andreessen and Ben Horowitz. In this second episode of a two-part series, Marc and Ben answer MORE questions about startup building in the post-COVID world.In this one-on-one conversation, Ben and Marc discuss how startups can think differently about organizational design and talent deployment, unpack the lore around layoffs, and even tackle the future of customer service. They also reveal some unexpected benefits of nicotine and Ozempic. That and more!* Watch the Full Episode: youtu.be/Fw4p85jSfQc?si=61qpPCCLEXOFOrS3
Startup Building: Challenges & Opportunities a16z 2024-05-02 | "It turns out the spreadsheet is not actually the business, despite what you may have learned in business school." - Ben HorowitzWelcome back to "The Ben & Marc Show" featuring a16z co-founders Marc Andreessen and Ben Horowitz. In this second episode of a two-part series, Marc and Ben answer MORE questions about startup building in the post-COVID world.In this one-on-one conversation, Ben and Marc discuss how startups can think differently about organizational design and talent deployment, unpack the lore around layoffs, and even tackle the future of customer service. They also reveal some unexpected benefits of nicotine and Ozempic. That and much more. Enjoy!*Watch Part 1→ youtu.be/-zzrGs5Z1ykTopics Covered:00:00:00 Teaser00:00:33 Intro00:01:04 How startups should think differently about talent deployment00:06:29 How a CEO can designate hybrid vs. remote 00:09:14 Extreme barbell for truly creative work00:11:46 Can you have a high functioning company where executives are not together?00:17:18 Productivity improvement in the economy is the function of downs cycles 00:29:18 The lore around layoffs 00:34:01 Price's Law00:41:30 Is a one person $1B company possible?00:47:34 Llama 3 and training AI models00:50:18 AI and customer service00:55:23 California's Covid policy and it's repercussions01:01:19 New forms of customer service01:05:02 Caffeine and nicotine01:09:18 Weight loss drugs and fertility01:11:10 Post-Covid real estate crisis 01:14:27 Regional bank crisis01:20:54 Sign off#startups #business #work #technology #entrepreneur #realestate #ai #entrepreneurship #boeing #tech #covid19 #vc #founders #future #a16z Listen to Us!- Apple: bit.ly/3SdsfNt- Spotify: https://spoti.fi/3SclPOrResources:Marc on X: twitter.com/pmarca Marc’s Substack: pmarca.substack.com Ben on X: twitter.com/bhorowitz Stay Updated: Find us on X: twitter.com/a16z Find us on LinkedIn: linkedin.com/company/a16z The views expressed here are those of the individual personnel quoted and are not the views of a16z or its affiliates. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors and may not under any circumstances be relied upon when making a decision to invest in any a16z funds. PLEASE SEE MORE HERE: a16z.com/disclosures
Placing Multiple Bets On a Mosaic of Solutions a16z 2024-04-30 | In a new episode of In the Vault, a16z General Partner Angela Strange talks with Jeff Sloan, former CEO of Global Payments, about how he was early to spot significant industry trends, how to make bets that move an organization, and the sea change that AI represents for the financial services industry.“In the Vault” is a new audio podcast series by the a16z Fintech team, where we sit down with the most influential figures in financial services to explore key trends impacting the industry and the pressing innovations that will shape our future. Follow this show on our podcast feed so you don't miss an episode.0:00 - Intro1:40 - Joining Global Payments8:15 - Placing many bets19:30 - Deal integration and scale advantage26:10 - GenAI sea change32:19 - OutroResources: Find "In The Vault" on a16z.com: a16z.com/podcasts/in-the-vault Find more about a16z's vision for the future of fintech: a16z.com/banking-on-AIFind Name Angela Strange on Twitter: twitter.com/astrangeFind a16z on Twitter: twitter.com/a16z Find a16z on LinkedIn: linkedin.com/company/a16z Subscribe to the a16z Fintech newsletter: info.a16z.com/newsletters-fintech.html
Turning Developers into Clients a16z 2024-04-30 | In a new episode of In the Vault, a16z General Partner David Haber talks with Marco Argenti, the chief information officer at Goldman Sachs, about bringing fintech processes into financial services, turning developers into clients, and how AI is a major inflection point in the history of technology.“In the Vault” is a new audio podcast series by the a16z Fintech team, where we sit down with the most influential figures in financial services to explore key trends impacting the industry and the pressing innovations that will shape our future.0:00 - Intro1:30 - From tech to financial services12:05 - Turning developers into clients17:30 - GenAI and productivity23:50 - The future of financial services28:50 - OutroResources: Find "In The Vault" on a16z.com: a16z.com/podcasts/in-the-vault Find more about a16z's vision for the future of fintech: a16z.com/banking-on-AIFind David Haber on Twitter: twitter.com/dhaberFind Marco Argenti on Twitter: twitter.com/marcoargenti?lang=enFind a16z on Twitter: twitter.com/a16z Find a16z on LinkedIn: linkedin.com/company/a16z Subscribe to the a16z Fintech newsletter: info.a16z.com/newsletters-fintech.html
Finding a Single Source of AI Truth a16z 2024-04-30 | In a new episode of In the Vault, a16z General Partner David Haber talks with Marty Chavez, vice chairman and partner at Sixth Street Partners, about the foundational role he’s had in merging technology and finance throughout his career, and the magical promises and regulatory pitfalls of AI.“In the Vault” is a new audio podcast series by the a16z Fintech team, where we sit down with the most influential figures in financial services to explore key trends impacting the industry and the pressing innovations that will shape our future.0:00 - Intro1:30 - From tech to Wall Street12:50 - SecDB in the 2008 financial crisis32:10 - GenAI's impact on finance36:15 - AI and biotech37:06 OutroResources: Find "In The Vault" on a16z.com: a16z.com/podcasts/in-the-vault Find more about a16z's vision for the future of fintech: a16z.com/banking-on-AIFind David Haber on Twitter: twitter.com/dhaberFind Name #2 on Twitter: twitter.com/RMartinChavezFind a16z on Twitter: twitter.com/a16z Find a16z on LinkedIn: linkedin.com/company/a16z Subscribe to the a16z Fintech newsletter: info.a16z.com/newsletters-fintech.html
Startup Building: Major Shifts in Tech & Culture a16z 2024-04-24 | Welcome to "The Ben & Marc Show" featuring a16z co-founders Marc Andreessen and Ben Horowitz. In this first episode in a two-part series, Marc and Ben answer YOUR questions about startup building in the post-COVID world.In this one-on-one conversation, Ben and Marc unpack the biggest tech and cultural disruptions in recent time, including loss of trust in institutions, major problems facing American cities – including crime and the commercial real estate crisis – and even the relevancy of our 40-hour work week. That and much more. Enjoy! * WATCH PART 2 → youtu.be/Fw4p85jSfQcTopics Covered:00:00:00 Teaser00:00:34 Intro00:01:32 Biggest tech disruptions out of COVID 00:07:42 Massive blow to societal trust in institutions and authority00:14:57 How our cities have evolved post-COVID00:17:43 Commercial real estate crisis00:21:54 Rise of urban crime 00:27:02 Massive societal shifts during COVID00:33:05 Future of the 40 hour work week00:48:50 How do we measure productivity?00:50:22 A need for education AND productive work00:57:27 Prognosis of HR departments01:09:05 Culture in the new post-COVID world01:14:18 What a CEO can do to maintain cultural coherence 01:18:20 Sign off#startups #business #work #technology #entrepreneur #entrepreneurship #tech #covid19 #vc #realestate #future #culture #a16z Listen to Us!- Apple: bit.ly/3SdsfNt- Spotify: https://spoti.fi/3SclPOrResources:Marc on X: twitter.com/pmarca Marc’s Substack: pmarca.substack.com Ben on X: twitter.com/bhorowitz Book mentioned on this episode: - “The Jungle” by Upton Sinclair amzn.to/3Ue2snAFilms mentioned on this episode: - “The Graduate” (1967; Dir. Mike Nichols) amzn.to/44a7BSi- “The Hunt for Red October” (1990; Dir. John McTiernan) amzn.to/3UvYc4jStay Updated: Find us on X: twitter.com/a16z Find us on LinkedIn: linkedin.com/company/a16z The views expressed here are those of the individual personnel quoted and are not the views of a16z or its affiliates. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors and may not under any circumstances be relied upon when making a decision to invest in any a16z funds. PLEASE SEE MORE HERE: a16z.com/disclosures
